{"id":"https://openalex.org/W58012858","doi":"https://doi.org/10.1007/s00213-012-2953-0","title":"The relationship between antipsychotic D2 occupancy and change in frontal metabolism and working memory","display_name":"The relationship between antipsychotic D2 occupancy and change in frontal metabolism and working memory","publication_year":2012,"publication_date":"2012-12-27","ids":{"openalex":"https://openalex.org/W58012858","doi":"https://doi.org/10.1007/s00213-012-2953-0","mag":"58012858","pmid":"https://pubmed.ncbi.nlm.nih.gov/23271192"},"language":"en","primary_location":{"id":"doi:10.1007/s00213-012-2953-0","doi":"https://doi.org/10.1007/s00213-012-2953-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00213-012-2953-0","pdf_url":null,"source":{"id":"https://openalex.org/S80334769","display_name":"Psychopharmacology","issn_l":"0033-3158","issn":["0033-3158","1432-2072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychopharmacology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020102478","display_name":"Euitae Kim","orcid":"https://orcid.org/0000-0003-0914-2331","observed_orcids":["https://orcid.org/0000-0003-0914-2331"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I2801748203","display_name":"Hammersmith Hospital","ror":"https://ror.org/05jg8yp15","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2801748203"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB","KR"],"is_corresponding":false,"raw_author_name":"Euitae Kim","raw_affiliation_strings":["Department of Psychiatry, Seoul National University College of Medicine, 28 Yeongon-dong, Chongno-gu, Seoul, 110-744, South Korea","Department of Psychiatry, Seoul National University College of Medicine, Chongno-gu, South Korea","King\u2019s College London, Institute of Psychiatry, London, UK","Psychiatric Imaging, Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Seoul National University College of Medicine, 28 Yeongon-dong, Chongno-gu, Seoul, 110-744, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Psychiatry, Seoul National University College of Medicine, Chongno-gu, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"King\u2019s College London, Institute of Psychiatry, London, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Psychiatric Imaging, Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, London, UK","institution_ids":["https://openalex.org/I2801748203","https://openalex.org/I47508984","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001601365","display_name":"Oliver David Howes","orcid":"https://orcid.org/0000-0002-2928-1972","observed_orcids":["https://orcid.org/0000-0002-2928-1972"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I2801748203","display_name":"Hammersmith Hospital","ror":"https://ror.org/05jg8yp15","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2801748203"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Oliver D. Howes","raw_affiliation_strings":["King\u2019s College London, Institute of Psychiatry, London, SE5 8AF, UK","Psychiatric Imaging, Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, London, W12 0NN, UK","King\u2019s College London, Institute of Psychiatry, London, UK","Psychiatric Imaging, Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King\u2019s College London, Institute of Psychiatry, London, SE5 8AF, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Psychiatric Imaging, Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, London, W12 0NN, UK","institution_ids":["https://openalex.org/I2801748203","https://openalex.org/I47508984","https://openalex.org/I90344618"]},{"raw_affiliation_string":"King\u2019s College London, Institute of Psychiatry, London, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Psychiatric Imaging, Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, London, UK","institution_ids":["https://openalex.org/I2801748203","https://openalex.org/I47508984","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079810332","display_name":"Federico Turkheimer","orcid":"https://orcid.org/0000-0002-3766-3815","observed_orcids":["https://orcid.org/0000-0002-3766-3815"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Federico E. Turkheimer","raw_affiliation_strings":["Department of Neuroimaging, Institute of Psychiatry, King\u2019s College London, London, SE5 8AF, UK","Department of Neuroimaging, Institute of Psychiatry, King's College London London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroimaging, Institute of Psychiatry, King\u2019s College London, London, SE5 8AF, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Department of Neuroimaging, Institute of Psychiatry, King's College London London, UK","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030905874","display_name":"Bo\u2010Hyung Kim","orcid":"https://orcid.org/0000-0003-3233-2918","observed_orcids":["https://orcid.org/0000-0003-3233-2918"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Bo-Hyung Kim","raw_affiliation_strings":["Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 110-744, South Korea","Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 110-744, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, South Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090893923","display_name":"Jae Min Jeong","orcid":"https://orcid.org/0000-0003-2611-6020","observed_orcids":["https://orcid.org/0000-0003-2611-6020","https://orcid.org/0009-0007-4101-7262"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jae Min Jeong","raw_affiliation_strings":["Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, 110-744, South Korea","Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, 110-744, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074680518","display_name":"Ju Whi Kim","orcid":"https://orcid.org/0000-0001-8011-3547","observed_orcids":["https://orcid.org/0000-0001-8011-3547"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ji Who Kim","raw_affiliation_strings":["Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, 110-744, South Korea","Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, 110-744, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100411630","display_name":"Jae Sung Lee","orcid":"https://orcid.org/0000-0001-7623-053X","observed_orcids":["https://orcid.org/0000-0001-7623-053X"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jae Sung Lee","raw_affiliation_strings":["Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, 110-744, South Korea","Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, 110-744, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064370332","display_name":"In\u2010Jin Jang","orcid":"https://orcid.org/0000-0002-8384-3139","observed_orcids":["https://orcid.org/0000-0002-8384-3139"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"In-Jin Jang","raw_affiliation_strings":["Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 110-744, South Korea","Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 110-744, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, South Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111636503","display_name":"Sang\u2010Goo Shin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sang-Goo Shin","raw_affiliation_strings":["Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 110-744, South Korea","Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 110-744, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, South Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037602769","display_name":"Shitij Kapur","orcid":"https://orcid.org/0000-0002-2231-2924","observed_orcids":["https://orcid.org/0000-0002-2231-2924"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Shitij Kapur","raw_affiliation_strings":["King\u2019s College London, Institute of Psychiatry, London, SE5 8AF, UK","King's College London; Institute of Psychiatry; London UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King\u2019s College London, Institute of Psychiatry, London, SE5 8AF, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"King's College London; Institute of Psychiatry; London UK","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027055033","display_name":"Jun Soo Kwon","orcid":"https://orcid.org/0000-0002-1060-1462","observed_orcids":["https://orcid.org/0000-0002-1060-1462"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jun Soo Kwon","raw_affiliation_strings":["Brain and Cognitive Science-WCU program, Seoul National University College of Natural Sciences, Seoul, 151-747, South Korea","Department of Psychiatry, Seoul National University College of Medicine, 28 Yeongon-dong, Chongno-gu, Seoul, 110-744, South Korea","Brain and Cognitive Science-WCU program, Seoul National University College of Natural Sciences, Seoul, South Korea","Department of Psychiatry, Seoul National University College of Medicine, Chongno-gu, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brain and Cognitive Science-WCU program, Seoul National University College of Natural Sciences, Seoul, 151-747, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Psychiatry, Seoul National University College of Medicine, 28 Yeongon-dong, Chongno-gu, Seoul, 110-744, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Brain and Cognitive Science-WCU program, Seoul National University College of Natural Sciences, Seoul, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Psychiatry, Seoul National University College of Medicine, Chongno-gu, South Korea","institution_ids":["https://openalex.org/I139264467"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5027055033"],"corresponding_institution_ids":["https://openalex.org/I139264467"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":3.1808,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.90494438,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"227","issue":"2","first_page":"221","last_page":"229"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aripiprazole","display_name":"aripiprazole","score":1.0},{"id":"https://openalex.org/keywords/dopamine-d2-receptor-occupancy","display_name":"dopamine D2 receptor occupancy","score":0.9750000238418579},{"id":"https://openalex.org/keywords/working-memory","display_name":"working memory","score":0.9779999852180481},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.8059999942779541},{"id":"https://openalex.org/keywords/intermediate-biomarkers","display_name":"intermediate biomarkers","score":0.6489999890327454},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.5820000171661377},{"id":"https://openalex.org/keywords/reaction-time","display_name":"reaction time","score":0.7509999871253967},{"id":"https://openalex.org/keywords/n-back-task","display_name":"n-back task","score":0.718999981880188},{"id":"https://openalex.org/keywords/fdg-pet","display_name":"FDG-PET","score":0.6330000162124634},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.6600000262260437}],"concepts":[{"id":"https://openalex.org/C21963081","wikidata":"https://www.wikidata.org/wiki/Q11337567","display_name":"Working memory","level":3,"score":0.682301938533783},{"id":"https://openalex.org/C2780494398","wikidata":"https://www.wikidata.org/wiki/Q208144","display_name":"Antipsychotic","level":3,"score":0.6696070432662964},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6141013503074646},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.565622091293335},{"id":"https://openalex.org/C160331591","wikidata":"https://www.wikidata.org/wiki/Q7075743","display_name":"Occupancy","level":2,"score":0.4272942543029785},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3535783886909485},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.31578052043914795},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.16299617290496826},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12106180191040039},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000068180","descriptor_name":"Aripiprazole","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002250","descriptor_name":"Carbon Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D010879","descriptor_name":"Piperazines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010879","descriptor_name":"Piperazines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011930","descriptor_name":"Reaction Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D016037","descriptor_name":"Single-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020891","descriptor_name":"Raclopride","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s00213-012-2953-0","doi":"https://doi.org/10.1007/s00213-012-2953-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00213-012-2953-0","pdf_url":null,"source":{"id":"https://openalex.org/S80334769","display_name":"Psychopharmacology","issn_l":"0033-3158","issn":["0033-3158","1432-2072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychopharmacology","raw_type":"journal-article"},{"id":"pmid:23271192","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23271192","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychopharmacology","raw_type":"Journal Article"},{"id":"pmh:oai:kclpure.kcl.ac.uk:publications/76a3faf8-af0c-421e-8939-c4dfcfcb03dc","doi":null,"is_oa":false,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/76a3faf8-af0c-421e-8939-c4dfcfcb03dc","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Kim, E, Howes, O D, Turkheimer, F E, Kim, B-H, Jeong, J M, Kim, J W, Lee, J S, Jang, I-J, Shin, S-G, Kapur, S & Kwon, J S 2013, 'The relationship between antipsychotic D-2 occupancy and change in frontal metabolism and working memory', Psychopharmacology, vol. 227, no. 2, pp. 221-229. https://doi.org/10.1007/s00213-012-2953-0","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W777578576","https://openalex.org/W1518890501","https://openalex.org/W1561375480","https://openalex.org/W1601443637","https://openalex.org/W1969133861","https://openalex.org/W1977138162","https://openalex.org/W1988694821","https://openalex.org/W1993326639","https://openalex.org/W1993693164","https://openalex.org/W1993734032","https://openalex.org/W1994357188","https://openalex.org/W1996065499","https://openalex.org/W1998601548","https://openalex.org/W2000697043","https://openalex.org/W2004729128","https://openalex.org/W2007709475","https://openalex.org/W2012007142","https://openalex.org/W2021872479","https://openalex.org/W2029814456","https://openalex.org/W2034457280","https://openalex.org/W2045930618","https://openalex.org/W2046835548","https://openalex.org/W2047016005","https://openalex.org/W2055569585","https://openalex.org/W2059669521","https://openalex.org/W2063017390","https://openalex.org/W2066640528","https://openalex.org/W2075093733","https://openalex.org/W2081308285","https://openalex.org/W2082654634","https://openalex.org/W2083618483","https://openalex.org/W2099797299","https://openalex.org/W2099921986","https://openalex.org/W2104281515","https://openalex.org/W2107266956","https://openalex.org/W2110387945","https://openalex.org/W2114801996","https://openalex.org/W2117671988","https://openalex.org/W2135333366","https://openalex.org/W2143870537","https://openalex.org/W2145056060","https://openalex.org/W2145602532","https://openalex.org/W2148538805","https://openalex.org/W2150311857","https://openalex.org/W2151331628","https://openalex.org/W2151444170","https://openalex.org/W2151818004","https://openalex.org/W2155554204","https://openalex.org/W2162707091","https://openalex.org/W2164512116","https://openalex.org/W2403157534"],"related_works":["https://openalex.org/W2799804903","https://openalex.org/W2281590068","https://openalex.org/W7118021967","https://openalex.org/W1988694821","https://openalex.org/W4412520699","https://openalex.org/W1552756713","https://openalex.org/W1993693164","https://openalex.org/W1934926274","https://openalex.org/W2055656125","https://openalex.org/W2145619523"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}