{"id":"https://openalex.org/W569188142","doi":null,"title":"PJ-396 Brain Natriuretic Peptide is Upregulated in Hypoxic Human Astrocytes Via Activation of c-Src-signaling Pathway and Exerts Anti-apoptotic Effect(Neurohumoral factors-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)","display_name":"PJ-396 Brain Natriuretic Peptide is Upregulated in Hypoxic Human Astrocytes Via Activation of c-Src-signaling Pathway and Exerts Anti-apoptotic Effect(Neurohumoral factors-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)","publication_year":2007,"publication_date":"2007-03-01","ids":{"openalex":"https://openalex.org/W569188142","mag":"569188142"},"language":"en","primary_location":{"id":"mag:569188142","doi":null,"is_oa":false,"landing_page_url":"https://ci.nii.ac.jp/naid/110006398072","pdf_url":null,"source":{"id":"https://openalex.org/S150042853","display_name":"Japanese Circulation Journal-english Edition","issn_l":"0047-1828","issn":["0047-1828","1347-4839"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Japanese Circulation Journal-english Edition","raw_type":null},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040104499","display_name":"Yoshitaka Shintomi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yoshitaka Shintomi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073078229","display_name":"Sunao Kojima","orcid":"https://orcid.org/0000-0002-1916-7252","observed_orcids":["https://orcid.org/0000-0002-1916-7252"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sunao Kojima","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1916-7252","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102713470","display_name":"Michihiro Yoshimura","orcid":"https://orcid.org/0000-0003-2828-7229","observed_orcids":["https://orcid.org/0000-0003-2828-7229"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michihiro Yoshimura","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2828-7229","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075403819","display_name":"Seigo Sugiyama","orcid":"https://orcid.org/0000-0003-2494-0374","observed_orcids":["https://orcid.org/0000-0003-2494-0374"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Seigo Sugiyama","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2494-0374","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079485654","display_name":"Koichi Kaikita","orcid":"https://orcid.org/0000-0003-2962-8056","observed_orcids":["https://orcid.org/0000-0003-2962-8056"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Koichi Kaikita","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2962-8056","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015115080","display_name":"Hirofumi Soejima","orcid":"https://orcid.org/0000-0002-7520-2008","observed_orcids":["https://orcid.org/0000-0002-7520-2008"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hirofumi Soejima","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7520-2008","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103984179","display_name":"Yoko Horibata","orcid":"https://orcid.org/0009-0000-5357-6773","observed_orcids":["https://orcid.org/0009-0000-5357-6773"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yoko Horibata","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032025783","display_name":"Yasuhiro Nagayoshi","orcid":"https://orcid.org/0000-0002-1696-0466","observed_orcids":["https://orcid.org/0000-0002-1696-0466"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yasuhiro Nagayoshi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1696-0466","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5020090012","display_name":"Hisao Ogawa","orcid":"https://orcid.org/0000-0003-2532-6130","observed_orcids":["https://orcid.org/0000-0003-2532-6130"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hisao Ogawa","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2532-6130","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"71","issue":null,"first_page":"571","last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.10920000076293945,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.10920000076293945,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12082","display_name":"Takotsubo Cardiomyopathy and Associated Phenomena","score":0.08869999647140503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.0723000019788742,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brain-natriuretic-peptide","display_name":"brain natriuretic peptide","score":1.0},{"id":"https://openalex.org/keywords/hypoxia","display_name":"hypoxia","score":0.8529999852180481},{"id":"https://openalex.org/keywords/astrocytes","display_name":"astrocytes","score":0.949999988079071},{"id":"https://openalex.org/keywords/anti-apoptotic-effects","display_name":"anti-apoptotic effects","score":0.9369999766349792},{"id":"https://openalex.org/keywords/neurohumoral-factors","display_name":"neurohumoral factors","score":0.7720000147819519},{"id":"https://openalex.org/keywords/cerebral-ischemia","display_name":"cerebral ischemia","score":0.4659999907016754}],"concepts":[{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.6673325300216675},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.5849575996398926},{"id":"https://openalex.org/C108636557","wikidata":"https://www.wikidata.org/wiki/Q21109354","display_name":"Proto-oncogene tyrosine-protein kinase Src","level":3,"score":0.5352702140808105},{"id":"https://openalex.org/C2775846464","wikidata":"https://www.wikidata.org/wiki/Q66360952","display_name":"Brain natriuretic peptide","level":3,"score":0.49814653396606445},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4457031786441803},{"id":"https://openalex.org/C8741621","wikidata":"https://www.wikidata.org/wiki/Q18030203","display_name":"NPR1","level":4,"score":0.439628928899765},{"id":"https://openalex.org/C2775915353","wikidata":"https://www.wikidata.org/wiki/Q1571529","display_name":"Natriuretic peptide","level":3,"score":0.4369077980518341},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.410243958234787},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.40870559215545654},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3597717881202698},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.34142744541168213},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3154970407485962},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28802648186683655},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2855287492275238},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09930825233459473},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09404310584068298},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:569188142","doi":null,"is_oa":false,"landing_page_url":"https://ci.nii.ac.jp/naid/110006398072","pdf_url":null,"source":{"id":"https://openalex.org/S150042853","display_name":"Japanese Circulation Journal-english Edition","issn_l":"0047-1828","issn":["0047-1828","1347-4839"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Japanese Circulation Journal-english Edition","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2122724197","https://openalex.org/W2474665929","https://openalex.org/W2048180287","https://openalex.org/W1980929921","https://openalex.org/W3147025502","https://openalex.org/W578457010","https://openalex.org/W18831324","https://openalex.org/W427640990","https://openalex.org/W4255466401","https://openalex.org/W2305272940"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-21T07:43:02.447757","created_date":"2016-06-24T00:00:00"}