{"id":"https://openalex.org/W565395440","doi":null,"title":"Metabolic profiling : methods and protocols","display_name":"Metabolic profiling : methods and protocols","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W565395440","mag":"565395440"},"language":"en","primary_location":{"id":"pmh:oai:aleph.bib-bvb.de:BVB01-022481345","doi":null,"is_oa":false,"landing_page_url":"https://bvbr.bib-bvb.de:443/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022481345&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034592694","display_name":"Thomas Metz","orcid":"https://orcid.org/0000-0001-6049-3968","observed_orcids":["https://orcid.org/0000-0001-6049-3968","https://orcid.org/0000-0003-2448-6845"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Thomas Metz","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6049-3968","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5034592694"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.725,"has_fulltext":true,"cited_by_count":42,"citation_normalized_percentile":{"value":0.79145516,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.9229000210762024,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.9229000210762024,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.07509999722242355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metabolic-profiling","display_name":"metabolite profiling","score":0.9639999866485596},{"id":"https://openalex.org/keywords/metabolomics","display_name":"metabolomics","score":0.8299999833106995},{"id":"https://openalex.org/keywords/inborn-errors-of-metabolism","display_name":"inborn errors of metabolism","score":0.9909999966621399},{"id":"https://openalex.org/keywords/amino-acid-profiling","display_name":"amino acid profiling","score":0.8500000238418579},{"id":"https://openalex.org/keywords/acylcarnitines","display_name":"acylcarnitines","score":0.9829999804496765},{"id":"https://openalex.org/keywords/organic-acids","display_name":"organic acids","score":0.9490000009536743},{"id":"https://openalex.org/keywords/purines-and-pyrimidines","display_name":"purines and pyrimidines","score":0.8880000114440918},{"id":"https://openalex.org/keywords/bile-acids","display_name":"bile acids","score":0.9959999918937683},{"id":"https://openalex.org/keywords/glycolytic-intermediates","display_name":"glycolytic intermediates","score":0.9679999947547913},{"id":"https://openalex.org/keywords/citric-acid-cycle-intermediates","display_name":"citric acid cycle intermediates","score":0.9869999885559082},{"id":"https://openalex.org/keywords/pentose-phosphate-pathway","display_name":"pentose phosphate pathway","score":0.8980000019073486},{"id":"https://openalex.org/keywords/gcxgc-tofms","display_name":"GCxGC-TOFMS","score":0.8669999837875366},{"id":"https://openalex.org/keywords/polar-metabolites","display_name":"polar metabolites","score":0.8309999704360962},{"id":"https://openalex.org/keywords/tandem-mass-spectrometry","display_name":"tandem mass spectrometry","score":0.8420000076293945}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.764728307723999},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.7295190095901489},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.7113367319107056},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.5416150689125061},{"id":"https://openalex.org/C123460561","wikidata":"https://www.wikidata.org/wiki/Q677065","display_name":"Gas chromatography","level":2,"score":0.5250111222267151},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.4424329996109009},{"id":"https://openalex.org/C21565614","wikidata":"https://www.wikidata.org/wiki/Q12149006","display_name":"Metabolomics","level":2,"score":0.4368486702442169},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11250185966491699}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:aleph.bib-bvb.de:BVB01-022481345","doi":null,"is_oa":false,"landing_page_url":"https://bvbr.bib-bvb.de:443/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022481345&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"mag:565395440","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/ncid/BB09150604","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Humana Press eBooks","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2954936567","https://openalex.org/W114963933","https://openalex.org/W97648961","https://openalex.org/W60557952","https://openalex.org/W4214590524","https://openalex.org/W2038946541","https://openalex.org/W1972367810","https://openalex.org/W1932721724","https://openalex.org/W1992717444","https://openalex.org/W2145130069"],"abstract_inverted_index":{"1.":[0],"Origins":[1],"of":[2,19,22,60,68,72,87,96,100,138,160,181,226,236,273,304,365],"Metabolic":[3,356,370],"Profiling":[4,15,208,320,357],"Arthur":[5],"B.":[6],"Robinson":[7,11],"and":[8,36,44,54,63,76,81,89,110,133,144,154,175,196,220,245,253,276,286,302,310,333,363,378],"Noah":[9],"E.":[10],"2.":[12],"Amino":[13],"Acid":[14,115,163],"for":[16,65,91,233,271,348],"the":[17,66,92,161],"Diagnosis":[18,67,95],"Inborn":[20,70,98],"Errors":[21,71,99],"Metabolism":[23,73,101],"Monique":[24],"Piraud,":[25],"Severine":[26],"Ruet,":[27],"Sylvie":[28],"Boyer,":[29],"Cecile":[30],"Acquaviva,":[31],"Pascale":[32],"Clerc-Renaud,":[33],"David":[34,51],"Cheillan,":[35],"Christine":[37],"Vianey-Saban":[38],"3.":[39],"Acylcarnitines:":[40],"Analysis":[41,59,86,116,137,159,235,303],"in":[42,117],"Plasma":[43],"Whole":[45],"Blood":[46],"Using":[47,121,166],"Tandem":[48,292],"Mass":[49,293],"Spectrometry":[50,127,147,169,190,204,215,231,260,268,294],"S.":[52,171],"Millington":[53],"Robert":[55],"D.":[56,210],"Stevens":[57],"4.":[58],"Organic":[61],"Acids":[62],"Acylglycines":[64],"Related":[69,97],"by":[74,187],"GC-":[75],"HPLC-MS":[77],"Giancarlo":[78],"la":[79],"Marca":[80],"Cristiano":[82],"Rizzo":[83],"5.":[84],"HPLC":[85],"Purines":[88],"Pyrimidines":[90],"Clinical":[93],"Biochemical":[94],"Giuseppe":[102],"Lazzarino,":[103],"Angela":[104,155],"Maria":[105,246],"Amorini,":[106],"Valentina":[107],"Di":[108],"Pietro,":[109],"Barbara":[111],"Tavazzi":[112],"6.":[113],"Bile":[114],"Various":[118],"Biological":[119],"Samples":[120],"Ultra":[122],"Performance":[123,201],"Liquid":[124,188,202,266],"Chromatography/Electrospray":[125],"Ionization-Mass":[126,259],"(LC/ESI-MS)":[128],"Masahito":[129],"Hagio,":[130],"Megumi":[131],"Matsumoto,":[132],"Satoshi":[134],"Ishizuka":[135],"7.":[136],"Glycolytic":[139],"Intermediates":[140,165],"with":[141],"Ion":[142],"Chromatography-":[143],"Gas":[145,167,213,229],"Chromatography-Mass":[146,168,189,203,214,267],"Jan":[148],"C.":[149,331,376],"van":[150],"Dam,":[151],"Cor":[152],"Ras,":[153],"ten":[156],"Pierick":[157],"8.":[158],"Citric":[162],"Cycle":[164],"Rajan":[170],"Kombu,":[172],"Henri":[173],"Brunengraber,":[174],"Michelle":[176],"A.":[177],"Puchowicz":[178],"9.":[179],"Quantification":[180],"Pentose":[182],"Phosphate":[183],"Pathway":[184],"(PPP)":[185],"Metabolites":[186,238],"(LC-MS)":[191],"Amber":[192,241],"Jannasch,":[193],"Miroslav":[194],"Sedlak,":[195],"Jiri":[197,243],"Adamec":[198],"10.":[199],"High":[200,349],"(HPLC-MS)-Based":[205],"Drug":[206,318],"Metabolite":[207,319],"Ian":[209],"Wilson":[211],"11.":[212],"(GC-MS)-Based":[216],"Metabolomics":[217,250,262,306,329],"Antonia":[218],"Garcia":[219],"Coral":[221],"Barbas":[222],"12.":[223],"The":[224],"Use":[225],"Two":[227],"Dimensional":[228],"Chromatography-Time-of-Flight-Mass":[230],"(GCxGC-TOF-MS)":[232],"Metabolomic":[234],"Polar":[237],"Kimberly":[239],"Ralston-Hooper,":[240],"Jannash,":[242],"Adamec,":[244],"Sepulveda":[247],"13.":[248],"LC-MS-Based":[249],"Sunil":[251],"Bajad":[252],"Vladimir":[254],"Shulaev":[255],"14.":[256],"Capillary":[257],"Electrophoresis-Electrospray":[258],"(CE-ESI-MS)-Based":[261],"Philip":[263],"Britz-McKibbin":[264],"15.":[265],"(LC-MS)-Based":[269],"Lipidomics":[270,297],"Studies":[272],"Body":[274],"Fluids":[275],"Tissues":[277],"Heli":[278],"Nygren,":[279],"Tuulikki":[280],"Seppanen-Laakso,":[281],"Sandra":[282],"Castillo,":[283],"Tuulia":[284],"Hyotylainen,":[285],"Matej":[287],"Oresic":[288],"16.":[289],"Electrospray":[290],"Ionization":[291],"(ESI-MS/MS)-Based":[295],"Shotgun":[296],"Giorgis":[298],"Isaac":[299],"17.":[300],"Processing":[301,362],"GC/LC-MS-Based":[305],"Data":[307],"Elizabeth":[308],"Want":[309],"Perrine":[311],"Masson":[312],"18.":[313],"Nuclear":[314,325,352,366],"Magnetic":[315,326,353,367],"Resonance":[316,327,354,368],"(NMR)-Based":[317,328],"Eva":[321],"M.":[322],"Lenz":[323],"19.":[324],"Hector":[330],"Keun":[332],"Toby":[334],"J.":[335],"Athersuch":[336],"20.":[337],"Slow":[338],"Magic":[339],"Angle":[340],"Sample":[341],"Spinning:":[342],"A":[343],"Non-":[344],"or":[345],"Minimal-Invasive":[346],"Method":[347],"Resolution":[350],"1H":[351],"(NMR)":[355,369],"Jian":[358],"Zhi":[359],"Hu":[360],"21.":[361],"Modeling":[364],"Profiles":[371],"Timothy":[372],"M.D.":[373],"Ebbels,":[374],"John":[375],"Lindon,":[377],"Muireann":[379],"Coen":[380]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}