{"id":"https://openalex.org/W56322622","doi":null,"title":"Expression of Chemerin and it\u2032s receptor in liver of mouse with nonalcoholic fatty liver disease induced by high fat diet","display_name":"Expression of Chemerin and it\u2032s receptor in liver of mouse with nonalcoholic fatty liver disease induced by high fat diet","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W56322622","mag":"56322622"},"language":"en","primary_location":{"id":"mag:56322622","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-XXYX200903002.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764624436","display_name":"Xinxiang yixueyuan xuebao","issn_l":"1004-7239","issn":["1004-7239"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4324262947","host_organization_name":"Xinxiang Medical College","host_organization_lineage":["https://openalex.org/P4324262947"],"host_organization_lineage_names":["Xinxiang Medical College"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Xinxiang yixueyuan xuebao","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100786366","display_name":"Qiang Zhang","orcid":"https://orcid.org/0000-0002-0769-7096","observed_orcids":["https://orcid.org/0000-0002-0769-7096"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qiang Zhang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0769-7096","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103737471","display_name":"Zhu Rong-feng","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhu Rong-feng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5003705114","display_name":"Shuang Liu","orcid":"https://orcid.org/0000-0002-6401-7317","observed_orcids":["https://orcid.org/0000-0002-6401-7317"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shuang Liu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6401-7317","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00632753,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"3","first_page":"224","last_page":"228"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.005799999926239252,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemerin","display_name":"chemerin","score":0.9629999995231628},{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":0.9160000085830688},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.9430000185966492},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.8809999823570251},{"id":"https://openalex.org/keywords/liver","display_name":"liver","score":0.4410000145435333},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9319999814033508},{"id":"https://openalex.org/keywords/triglyceride-accumulation","display_name":"triglyceride accumulation","score":0.6949999928474426},{"id":"https://openalex.org/keywords/hepatic-gene-expression","display_name":"hepatic gene expression","score":0.5559999942779541}],"concepts":[{"id":"https://openalex.org/C199901988","wikidata":"https://www.wikidata.org/wiki/Q18031045","display_name":"Chemerin","level":5,"score":0.906150221824646},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8451840281486511},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8382236361503601},{"id":"https://openalex.org/C2776954865","wikidata":"https://www.wikidata.org/wiki/Q1546498","display_name":"Nonalcoholic fatty liver disease","level":4,"score":0.8284837007522583},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.6233058571815491},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.582637369632721},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.5371986031532288},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40775778889656067},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3653500974178314},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.3296669125556946},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.3050878047943115},{"id":"https://openalex.org/C194832188","wikidata":"https://www.wikidata.org/wiki/Q2638593","display_name":"Adipokine","level":4,"score":0.15072637796401978},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.06878811120986938}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:56322622","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-XXYX200903002.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764624436","display_name":"Xinxiang yixueyuan xuebao","issn_l":"1004-7239","issn":["1004-7239"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4324262947","host_organization_name":"Xinxiang Medical College","host_organization_lineage":["https://openalex.org/P4324262947"],"host_organization_lineage_names":["Xinxiang Medical College"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Xinxiang yixueyuan xuebao","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2591269639","https://openalex.org/W2103749847","https://openalex.org/W2327303882","https://openalex.org/W2182518296","https://openalex.org/W2548217573","https://openalex.org/W3030507229","https://openalex.org/W2006307216","https://openalex.org/W2359812883","https://openalex.org/W7097735237","https://openalex.org/W2050253851"],"abstract_inverted_index":{"Objective":[0],"To":[1],"investigate":[2],"the":[3,62,83,97,181],"expression":[4,103,172],"of":[5,12,71,85,100,105,128,155,167,183],"Chemerin":[6,8,129,168,170],"and":[7,36,51,82,90,107,135,140,169],"receptor(Chemerin-like-receptor1,CMKLR1)":[9],"in":[10,111,131,138,146,174],"liver":[11,17,86,112,132,158,176,186],"mouse":[13,175],"with":[14,122,163],"nonalcoholic":[15,156,184],"fatty":[16,74,157,185],"disease(NAFLD)induced":[18],"by":[19,115,189],"high":[20,37,43,147,190],"fat":[21,38,44,148,191],"diet.Methods":[22],"22":[23],"C57BL/6":[24],"mice":[25,63],"were":[26,32,41,55,64,88,113,144],"randomly":[27],"divided":[28],"into":[29],"control":[30,123],"group(n=10)which":[31],"given":[33,42],"common":[34],"feed":[35],"diet":[39,149],"group(n=12)which":[40],"diet.Eighteen":[45],"weeks":[46],"later,intraperitoneal":[47],"glucose":[48],"tolerance":[49,53],"test(IPGTT)":[50],"insulin":[52,59,125,164],"test(ITT)":[54],"performed":[56],"for":[57],"estimating":[58],"sensitivity,and":[60],"all":[61],"executed":[65],"three":[66],"days":[67],"after":[68],"ITT.The":[69],"levels":[70,104,127,173],"serum":[72],"free":[73],"acid(FFA),total":[75],"cholesterol(TC),triglyceride(TG),low":[76],"density":[77,79],"lipoprotein(LDL),high":[78],"lipoprotein(HDL),alanine":[80],"aminotransferase(ALT)":[81],"content":[84],"TG":[87,136],"detected":[89],"HE":[91],"dying":[92],"was":[93,133,160],"done":[94],"to":[95,180],"observe":[96],"morphologic":[98],"change":[99,166],"liver.The":[101],"mRNA":[102,130,142],"Chemerin,CMKLR1":[106],"tumor":[108],"necrosis":[109],"factor-\u03b1(TNF-\u03b1)":[110],"measured":[114],"real-time":[116],"polymerase":[117],"chain":[118],"reaction(RT-time":[119],"PCR).Results":[120],"Compared":[121],"group,the":[124],"sensitivity,expression":[126],"lower(P0.05)":[134],"contents":[137],"liver,CMKLR1":[139],"TNF-\u03b1":[141],"level":[143],"higher":[145],"group(P0.05).Conclusion":[150],"After":[151],"18":[152],"weeks,the":[153],"model":[154],"disease":[159,187],"constructed":[161],"successfully":[162],"resistance.The":[165],"receptor":[171],"may":[177],"be":[178],"related":[179],"development":[182],"induced":[188],"diet.":[192]},"counts_by_year":[],"updated_date":"2025-10-10T17:16:08.811792","created_date":"2016-06-24T00:00:00"}