{"id":"https://openalex.org/W55681016","doi":"https://doi.org/10.13097/archive-ouverte/unige:25589","title":"Dynamin-mediated membrane fission","display_name":"Dynamin-mediated membrane fission","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W55681016","doi":"https://doi.org/10.13097/archive-ouverte/unige:25589","mag":"55681016"},"language":"en","primary_location":{"id":"pmh:oai:unige.ch:unige:25589","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:25589","pdf_url":"https://archive-ouverte.unige.ch/unige:25589","source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://archive-ouverte.unige.ch/unige:25589","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041721488","display_name":"Sandrine Morlot","orcid":"https://orcid.org/0000-0002-0326-6694","observed_orcids":["https://orcid.org/0000-0002-0326-6694"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Morlot, Sandrine","raw_affiliation_strings":["Roux Lab, D\u00e9partement de Biochimie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roux Lab, D\u00e9partement de Biochimie","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5041721488"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dynamin","display_name":"dynamin","score":0.9900000095367432},{"id":"https://openalex.org/keywords/membrane-fission","display_name":"membrane fission","score":0.9959999918937683},{"id":"https://openalex.org/keywords/gtpase","display_name":"GTPase","score":0.7059999704360962},{"id":"https://openalex.org/keywords/clathrin-mediated-endocytosis","display_name":"clathrin-mediated endocytosis","score":0.9589999914169312},{"id":"https://openalex.org/keywords/membrane-constriction","display_name":"membrane constriction","score":0.7670000195503235},{"id":"https://openalex.org/keywords/giant-unilamellar-vesicles","display_name":"giant unilamellar vesicles","score":0.9110000133514404},{"id":"https://openalex.org/keywords/membrane-curvature","display_name":"membrane curvature","score":0.8140000104904175},{"id":"https://openalex.org/keywords/energy-barrier","display_name":"energy barrier","score":0.8730000257492065},{"id":"https://openalex.org/keywords/membrane-tension","display_name":"membrane tension","score":0.8840000033378601},{"id":"https://openalex.org/keywords/membrane-stiffness","display_name":"membrane rigidity","score":0.8899999856948853},{"id":"https://openalex.org/keywords/intracellular-transport","display_name":"intracellular transport","score":0.5479999780654907},{"id":"https://openalex.org/keywords/microbeads","display_name":"microbeads","score":0.40299999713897705}],"concepts":[{"id":"https://openalex.org/C12294094","wikidata":"https://www.wikidata.org/wiki/Q929080","display_name":"Fission","level":3,"score":0.8529272675514221},{"id":"https://openalex.org/C156407911","wikidata":"https://www.wikidata.org/wiki/Q420160","display_name":"Dynamin","level":4,"score":0.8213101625442505},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5874321460723877},{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.5656014680862427},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.5519275069236755},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.4631148874759674},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46106016635894775},{"id":"https://openalex.org/C207332259","wikidata":"https://www.wikidata.org/wiki/Q769143","display_name":"GTPase","level":2,"score":0.4482347369194031},{"id":"https://openalex.org/C2777278457","wikidata":"https://www.wikidata.org/wiki/Q6815124","display_name":"Membrane curvature","level":4,"score":0.4373665452003479},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21764478087425232},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.17579907178878784},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.17194581031799316},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13741856813430786},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.09237250685691833},{"id":"https://openalex.org/C152568617","wikidata":"https://www.wikidata.org/wiki/Q2348","display_name":"Neutron","level":2,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"pmh:oai:unige.ch:unige:25589","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:25589","pdf_url":"https://archive-ouverte.unige.ch/unige:25589","source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:55681016","doi":null,"is_oa":true,"landing_page_url":"https://theses.hal.science/tel-00766694","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"HAL (Le Centre pour la Communication Scientifique Directe)","raw_type":null},{"id":"pmh:hdl:10068/884342","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10068/884342","pdf_url":null,"source":{"id":"https://openalex.org/S4377196900","display_name":"OpenGrey (Institut de l'Information Scientifique et Technique)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1295345811","host_organization_name":"Institut de l'Information Scientifique et Technique","host_organization_lineage":["https://openalex.org/I1295345811"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"U - Thesis"},{"id":"pmh:oai:HAL:tel-00766694v1","doi":null,"is_oa":true,"landing_page_url":"https://theses.hal.science/tel-00766694","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biological Physics [physics.bio-ph]. University of Geneva; Universit\u00e9 Paris-Diderot - Paris VII, 2012. English. &#x27E8;NNT : &#x27E9;","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:unige.ch:aou:unige:25589","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:25589","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"doi:10.13097/archive-ouverte/unige:25589","doi":"https://doi.org/10.13097/archive-ouverte/unige:25589","is_oa":true,"landing_page_url":"https://doi.org/10.13097/archive-ouverte/unige:25589","pdf_url":null,"source":{"id":"https://openalex.org/S7407051284","display_name":"Uni Genf","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"}],"best_oa_location":{"id":"pmh:oai:unige.ch:unige:25589","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:25589","pdf_url":"https://archive-ouverte.unige.ch/unige:25589","source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"},{"id":"https://openalex.org/F4320324547","display_name":"Soci\u00e9t\u00e9 Acad\u00e9mique de Gen\u00e8ve","ror":"https://ror.org/04p4avd56"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W55681016.pdf","grobid_xml":"https://content.openalex.org/works/W55681016.grobid-xml"},"referenced_works_count":97,"referenced_works":["https://openalex.org/W267879079","https://openalex.org/W1493752155","https://openalex.org/W1554579611","https://openalex.org/W1564784444","https://openalex.org/W1570552209","https://openalex.org/W1574831557","https://openalex.org/W1585616862","https://openalex.org/W1603606435","https://openalex.org/W1618955965","https://openalex.org/W1963573377","https://openalex.org/W1965940344","https://openalex.org/W1968827563","https://openalex.org/W1970916267","https://openalex.org/W1971060242","https://openalex.org/W1972812883","https://openalex.org/W1972859350","https://openalex.org/W1979870487","https://openalex.org/W1980798766","https://openalex.org/W1981054060","https://openalex.org/W1981431290","https://openalex.org/W1989417741","https://openalex.org/W1989540421","https://openalex.org/W1990363090","https://openalex.org/W1992425845","https://openalex.org/W1992721127","https://openalex.org/W1993706961","https://openalex.org/W1995950736","https://openalex.org/W1999679029","https://openalex.org/W1999819298","https://openalex.org/W2000678571","https://openalex.org/W2003959866","https://openalex.org/W2004083812","https://openalex.org/W2004939344","https://openalex.org/W2004942398","https://openalex.org/W2005025746","https://openalex.org/W2005374373","https://openalex.org/W2006999571","https://openalex.org/W2009612127","https://openalex.org/W2010651460","https://openalex.org/W2012085812","https://openalex.org/W2013327420","https://openalex.org/W2015011519","https://openalex.org/W2015276938","https://openalex.org/W2015737472","https://openalex.org/W2023236182","https://openalex.org/W2023863818","https://openalex.org/W2024136850","https://openalex.org/W2026007053","https://openalex.org/W2026049773","https://openalex.org/W2028416032","https://openalex.org/W2029732834","https://openalex.org/W2032145912","https://openalex.org/W2040010587","https://openalex.org/W2041848251","https://openalex.org/W2053527054","https://openalex.org/W2054922048","https://openalex.org/W2055473408","https://openalex.org/W2058886576","https://openalex.org/W2059571424","https://openalex.org/W2062087600","https://openalex.org/W2067257899","https://openalex.org/W2069655536","https://openalex.org/W2074033410","https://openalex.org/W2075457034","https://openalex.org/W2079390173","https://openalex.org/W2079900215","https://openalex.org/W2083112247","https://openalex.org/W2084604716","https://openalex.org/W2087785106","https://openalex.org/W2090851364","https://openalex.org/W2091214639","https://openalex.org/W2094123735","https://openalex.org/W2096526911","https://openalex.org/W2100869615","https://openalex.org/W2104152706","https://openalex.org/W2104651163","https://openalex.org/W2121541490","https://openalex.org/W2121882207","https://openalex.org/W2122740029","https://openalex.org/W2125080444","https://openalex.org/W2125599080","https://openalex.org/W2125872855","https://openalex.org/W2133991651","https://openalex.org/W2134248543","https://openalex.org/W2136203552","https://openalex.org/W2136319664","https://openalex.org/W2139500266","https://openalex.org/W2139539366","https://openalex.org/W2140717014","https://openalex.org/W2146558872","https://openalex.org/W2153261854","https://openalex.org/W2153689647","https://openalex.org/W2157773619","https://openalex.org/W2158564511","https://openalex.org/W2168929121","https://openalex.org/W2264936970","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2022634792","https://openalex.org/W4296063840","https://openalex.org/W7096329074","https://openalex.org/W7148999216","https://openalex.org/W2096829751","https://openalex.org/W2976325446","https://openalex.org/W2035166519","https://openalex.org/W2082199934","https://openalex.org/W1985999321","https://openalex.org/W2129010183"],"abstract_inverted_index":{"La":[0,14,40,104,124,172,205],"cellule":[1],"eukaryote":[2],"est":[3,18,27,42,76,108,130,160,183,222],"organis\u00e9e":[4],"en":[5,61,110,211,215,220],"plusieurs":[6],"compartiments,":[7],"appel\u00e9s":[8],"organelles,":[9],"d\u00e9limit\u00e9s":[10],"par":[11,56,134,157,200],"des":[12,16,51,65,118,126,189],"membranes;":[13],"fission":[15,50,156,173,196,210,238],"membranes":[17],"n\u00e9cessaire":[19],"pour":[20,147],"le":[21,79,89,231],"transport":[22,31],"intracellulaire":[23],"entre":[24,137],"organelles.":[25,39],"L'endocytose":[26],"un":[28,100],"m\u00e9canisme":[29,101],"de":[30,74,83,92,102,106,114,122,128,164,168,178,191,195,209,213,217,234,237],"depuis":[32],"la":[33,49,57,72,112,135,142,148,155,158,181,193,235,245],"membrane":[34,138,182,218],"plasmique":[35],"vers":[36],"les":[37],"autres":[38],"Dynamine":[41,129,159],"une":[43,201],"guanosine":[44],"triphosphatase":[45],"(GTPase)":[46],"impliqu\u00e9e":[47],"dans":[48],"v\u00e9sicules":[52,169],"pendant":[53],"l'endocytose":[54],"m\u00e9di\u00e9e":[55],"Clathrine.":[58],"Elle":[59],"polymerise":[60],"h\u00e9lice":[62],"au":[63,176],"coup":[64],"bourgeons":[66],"endocytiques.":[67],"Apr\u00e8s":[68],"hydrolyse":[69],"du":[70,207],"GTP,":[71],"structure":[73],"l'h\u00e9lice":[75],"modifi\u00e9e":[77],":":[78],"rayon":[80],"interne":[81],"diminue":[82],"10":[84],"\u00e0":[85,94,117,162,242],"5":[86],"nm":[87],"et":[88,132,139,219,225,240],"pas":[90,146],"h\u00e9lical":[91],"13":[93],"9":[95],"nm.":[96],"Ces":[97],"modifications":[98],"indiquent":[99],"constriction.":[103],"dynamique":[105],"constriction":[107,143],"\u00e9tudi\u00e9e":[109,161],"suivant":[111],"rotation":[113],"microbilles":[115],"attach\u00e9es":[116],"tubes":[119,165],"lipidiques":[120,166],"recouverts":[121],"Dynamine.":[123,140],"d\u00e9formation":[125],"h\u00e9lices":[127],"concert\u00e9e":[131],"amortie":[133],"friction":[136],"Cependant":[141],"ne":[144],"suffit":[145],"fission.":[149],"Pour":[150],"comprendre":[151],"davantage":[152],"son":[153],"m\u00e9canisme,":[154],"l'aide":[163],"extraits":[167],"unilamellaires":[170],"g\u00e9antes.":[171],"se":[174],"produit":[175],"bord":[177],"l'h\u00e9lice,":[179],"o\u00f9":[180],"fortement":[184],"courb\u00e9e.":[185],"D'apr\u00e8s":[186],"l'analyse":[187],"statistique":[188],"temps":[190,208],"fission,":[192],"r\u00e9action":[194,236],"peut":[197],"\u00eatre":[198],"mod\u00e9lis\u00e9e":[199],"unique":[202],"barri\u00e8re":[203,246],"\u00e9nerg\u00e9tique.":[204,247],"d\u00e9pendance":[206],"rigidit\u00e9":[212],"membrane,":[214],"tension":[216],"couple":[221],"\u00e9tablie":[223],"th\u00e9oriquement":[224],"valid\u00e9e":[226],"exp\u00e9rimentalement.":[227],"Ce":[228],"travail":[229],"\u00e9tablit":[230],"profil":[232],"\u00e9nerg\u00e9tique":[233],"membranaire":[239],"\u00e9value":[241],"70":[243],"KBT":[244]},"counts_by_year":[],"updated_date":"2026-10-25T09:29:13.331239","created_date":"2016-06-24T00:00:00"}
