{"id":"https://openalex.org/W55014226","doi":"https://doi.org/10.1155/2012/235476","title":"Patient Satisfaction with Medication for Gastroesophageal Reflux Disease: A Systematic Review","display_name":"Patient Satisfaction with Medication for Gastroesophageal Reflux Disease: A Systematic Review","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W55014226","doi":"https://doi.org/10.1155/2012/235476","mag":"55014226","pmid":"https://pubmed.ncbi.nlm.nih.gov/22506259","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3354888"},"language":"en","primary_location":{"id":"doi:10.1155/2012/235476","doi":"https://doi.org/10.1155/2012/235476","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2012/235476","pdf_url":"https://downloads.hindawi.com/journals/cjgh/2012/235476.pdf","source":{"id":"https://openalex.org/S4210173357","display_name":"Canadian Journal of Gastroenterology","issn_l":"0835-7900","issn":["0835-7900","1916-7237"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310313016","host_organization_name":"Pulsus Group","host_organization_lineage":["https://openalex.org/P4310313016","https://openalex.org/P4310320466"],"host_organization_lineage_names":["Pulsus Group","OMICS Publishing Group"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://downloads.hindawi.com/journals/cjgh/2012/235476.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041177228","display_name":"Sander Veldhuyzen van Zanten","orcid":"https://orcid.org/0000-0002-1702-8750","observed_orcids":["https://orcid.org/0000-0002-1702-8750"]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Sander Veldhuyzen van Zanten","raw_affiliation_strings":["Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017114097","display_name":"Catherine Henderson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Catherine Henderson","raw_affiliation_strings":["Research Evaluation Unit, Oxford PharmaGenesis Ltd, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Evaluation Unit, Oxford PharmaGenesis Ltd, Oxford, UK","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032087491","display_name":"Nesta Hughes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nesta Hughes","raw_affiliation_strings":["Research Evaluation Unit, Oxford PharmaGenesis Ltd, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Evaluation Unit, Oxford PharmaGenesis Ltd, Oxford, UK","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5041177228"],"corresponding_institution_ids":["https://openalex.org/I154425047"],"apc_list":{"value":2100,"currency":"USD","value_usd":2100},"apc_paid":{"value":2100,"currency":"USD","value_usd":2100},"fwci":0.3037,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.27752809,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"26","issue":"4","first_page":"196","last_page":"204"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10671","display_name":"Gastroesophageal reflux and treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10671","display_name":"Gastroesophageal reflux and treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11722","display_name":"Patient Satisfaction in Healthcare","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gastroesophageal-reflux-disease","display_name":"gastroesophageal reflux disease","score":0.9629999995231628},{"id":"https://openalex.org/keywords/patient-satisfaction","display_name":"patient satisfaction","score":0.9980000257492065},{"id":"https://openalex.org/keywords/proton-pump-inhibitors","display_name":"proton pump inhibitors","score":0.9980000257492065},{"id":"https://openalex.org/keywords/symptom-improvement","display_name":"symptom improvement","score":0.8980000019073486},{"id":"https://openalex.org/keywords/health-related-quality-of-life","display_name":"health-related quality of life","score":0.9869999885559082},{"id":"https://openalex.org/keywords/on-demand-treatment","display_name":"on-demand treatment","score":0.8479999899864197},{"id":"https://openalex.org/keywords/continuous-treatment","display_name":"continuous treatment","score":0.7749999761581421}],"concepts":[{"id":"https://openalex.org/C2777014526","wikidata":"https://www.wikidata.org/wiki/Q223591","display_name":"GERD","level":4,"score":0.8667553663253784},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8460524082183838},{"id":"https://openalex.org/C2775944032","wikidata":"https://www.wikidata.org/wiki/Q22907659","display_name":"Patient satisfaction","level":2,"score":0.7533252239227295},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5869413614273071},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.516853392124176},{"id":"https://openalex.org/C43270747","wikidata":"https://www.wikidata.org/wiki/Q898610","display_name":"Reflux","level":3,"score":0.5089144706726074},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.483036607503891},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.4620800018310547},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.35963425040245056},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.17551380395889282}],"mesh":[{"descriptor_ui":"D000863","descriptor_name":"Antacids","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000863","descriptor_name":"Antacids","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D005764","descriptor_name":"Gastroesophageal Reflux","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D005764","descriptor_name":"Gastroesophageal Reflux","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D005764","descriptor_name":"Gastroesophageal Reflux","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006356","descriptor_name":"Heartburn","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006356","descriptor_name":"Heartburn","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006356","descriptor_name":"Heartburn","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010358","descriptor_name":"Patient Participation","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017060","descriptor_name":"Patient Satisfaction","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D018434","descriptor_name":"Sickness Impact Profile","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054328","descriptor_name":"Proton Pump Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D054328","descriptor_name":"Proton Pump Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D057045","descriptor_name":"Laryngopharyngeal Reflux","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D057045","descriptor_name":"Laryngopharyngeal Reflux","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D057045","descriptor_name":"Laryngopharyngeal Reflux","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1155/2012/235476","doi":"https://doi.org/10.1155/2012/235476","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2012/235476","pdf_url":"https://downloads.hindawi.com/journals/cjgh/2012/235476.pdf","source":{"id":"https://openalex.org/S4210173357","display_name":"Canadian Journal of Gastroenterology","issn_l":"0835-7900","issn":["0835-7900","1916-7237"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310313016","host_organization_name":"Pulsus Group","host_organization_lineage":["https://openalex.org/P4310313016","https://openalex.org/P4310320466"],"host_organization_lineage_names":["Pulsus Group","OMICS Publishing Group"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Gastroenterology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2611327","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3354888","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3354888","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3354888","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Can J Gastroenterol","raw_type":"Text"},{"id":"pmid:22506259","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22506259","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian journal of gastroenterology = Journal canadien de gastroenterologie","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:79aa3dfa08b049c98bed41d3548e07e2","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/79aa3dfa08b049c98bed41d3548e07e2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Canadian Journal of Gastroenterology, Vol 26, Iss 4, Pp 196-204 (2012)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1155/2012/235476","doi":"https://doi.org/10.1155/2012/235476","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2012/235476","pdf_url":"https://downloads.hindawi.com/journals/cjgh/2012/235476.pdf","source":{"id":"https://openalex.org/S4210173357","display_name":"Canadian Journal of Gastroenterology","issn_l":"0835-7900","issn":["0835-7900","1916-7237"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310313016","host_organization_name":"Pulsus Group","host_organization_lineage":["https://openalex.org/P4310313016","https://openalex.org/P4310320466"],"host_organization_lineage_names":["Pulsus Group","OMICS Publishing Group"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Gastroenterology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W55014226.pdf","grobid_xml":"https://content.openalex.org/works/W55014226.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W78086645","https://openalex.org/W207352992","https://openalex.org/W1512390910","https://openalex.org/W1935581134","https://openalex.org/W1954997772","https://openalex.org/W1963493659","https://openalex.org/W1964519086","https://openalex.org/W1965463528","https://openalex.org/W1977139604","https://openalex.org/W1981877378","https://openalex.org/W1989194917","https://openalex.org/W1993346080","https://openalex.org/W1998052119","https://openalex.org/W1999600314","https://openalex.org/W2002036551","https://openalex.org/W2010738941","https://openalex.org/W2022547798","https://openalex.org/W2022688944","https://openalex.org/W2032521184","https://openalex.org/W2036222272","https://openalex.org/W2042791083","https://openalex.org/W2042809466","https://openalex.org/W2044025770","https://openalex.org/W2053253142","https://openalex.org/W2060152915","https://openalex.org/W2064646374","https://openalex.org/W2067428872","https://openalex.org/W2074018949","https://openalex.org/W2080750722","https://openalex.org/W2089448885","https://openalex.org/W2090248636","https://openalex.org/W2094187658","https://openalex.org/W2114442699","https://openalex.org/W2115538863","https://openalex.org/W2118953347","https://openalex.org/W2126373160","https://openalex.org/W2129344224","https://openalex.org/W2130187548","https://openalex.org/W2136821381","https://openalex.org/W2151971125","https://openalex.org/W2156485717","https://openalex.org/W2163976024","https://openalex.org/W2324803705","https://openalex.org/W2345030036","https://openalex.org/W4233162397","https://openalex.org/W4237600793","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W1984352906","https://openalex.org/W4283313850","https://openalex.org/W2977392258","https://openalex.org/W2089448885","https://openalex.org/W2080750722","https://openalex.org/W1981877378","https://openalex.org/W2027018951","https://openalex.org/W1499387674","https://openalex.org/W63398132","https://openalex.org/W2054531470"],"abstract_inverted_index":{"BACKGROUND:":[0],"Patient":[1,95],"satisfaction":[2,40,96,181,189,206,239,248],"is":[3,249],"increasingly":[4],"regarded":[5],"as":[6,41],"an":[7],"important":[8],"aspect":[9],"of":[10,38,55,80,113,122,149,194,205,214],"measuring":[11],"treatment":[12,92,123,155,201,257],"success":[13],"in":[14,106,124,222],"individuals":[15],"with":[16,27,30,49,87,116,133,152,218,229],"gastroesophageal":[17],"reflux":[18],"disease":[19],"(GERD).":[20],"OBJECTIVE:":[21],"To":[22],"review":[23],"how":[24],"satisfied":[25,217,228],"patients":[26,81,114,150,215,226],"GERD":[28,104,256],"are":[29],"their":[31,117,153,219],"medication,":[32],"and":[33,58,64,70,163,182,185,190,224,240],"to":[34,78,131,138,161,168],"analyze":[35],"the":[36,56,146],"usefulness":[37],"patient":[39,65,180,238,247],"a":[42,176,250],"clinical":[43,62],"end":[44,252],"point":[45,253],"by":[46],"comparing":[47],"it":[48],"symptom":[50,183,241],"improvement.":[51],"METHODS:":[52],"Systematic":[53],"searches":[54],"PubMed":[57],"EMBASE":[59],"databases":[60],"identified":[61],"trials":[63,74,125,174,197],"surveys":[66,187],"published":[67],"between":[68,179,188,237],"1966":[69],"2009.":[71],"RESULTS:":[72],"Twelve":[73],"reported":[75],"that":[76,199,246],"56%":[77],"100%":[79],"were":[82,98,170,216,227],"'satisfied'":[83,115,151],"or":[84],"'very":[85,141,171],"satisfied'":[86],"proton":[88],"pump":[89],"inhibitor":[90],"(PPI)":[91],"for":[93,100,254],"GERD.":[94],"levels":[97],"higher":[99,203],"PPIs":[101,230],"than":[102,207,212,231],"other":[103,232],"medications":[105],"two":[107,186],"trials.":[108],"The":[109],"sample-size-weighted":[110],"average":[111,147],"proportion":[112,148],"PPI":[118,154,220],"after":[119],"four":[120,144],"weeks":[121],"was":[126,156,243],"93%":[127],"(95%":[128,135,158,165],"CI":[129,136,159,166],"87%":[130],"99%),":[132],"73%":[134,160],"62%":[137,164],"83%)":[139],"being":[140],"satisfied'.":[142,172],"In":[143],"surveys,":[145],"82%":[157],"90%)":[162],"48%":[167],"75%)":[169],"Seven":[173],"found":[175,198],"positive":[177],"association":[178,236],"improvement,":[184],"improved":[191],"health-related":[192],"quality":[193],"life.":[195],"Three":[196],"continuous":[200],"yielded":[202],"rates":[204],"on-demand":[208],"therapy.":[209],"CONCLUSIONS:":[210],"More":[211],"one-half":[213],"medication":[221,233],"trials,":[223],"more":[225],"types.":[234],"An":[235],"resolution":[242],"found,":[244],"suggesting":[245],"useful":[251],"evaluating":[255],"success.":[258]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":5}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
