{"id":"https://openalex.org/W5482163","doi":"https://doi.org/10.2967/jnumed.108.060467","title":"123I-MIBG scintigraphy and 18F-FDG PET in neuroblastoma.","display_name":"123I-MIBG scintigraphy and 18F-FDG PET in neuroblastoma.","publication_year":2009,"publication_date":"2009-08-01","ids":{"openalex":"https://openalex.org/W5482163","doi":"https://doi.org/10.2967/jnumed.108.060467","mag":"5482163","pmid":"https://pubmed.ncbi.nlm.nih.gov/19617326"},"language":"en","primary_location":{"id":"pmid:19617326","doi":"https://doi.org/10.2967/jnumed.108.060467","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19617326","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","raw_type":"Comparative Study"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051234105","display_name":"Susan E. Sharp","orcid":"https://orcid.org/0000-0002-0477-8624","observed_orcids":["https://orcid.org/0000-0002-0477-8624"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan E Sharp","raw_affiliation_strings":["Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA. susan.sharp@cchmc.org","2Cincinnati Children's Hospital, Cincinnati, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA. susan.sharp@cchmc.org","institution_ids":["https://openalex.org/I1285204247"]},{"raw_affiliation_string":"2Cincinnati Children's Hospital, Cincinnati, Ohio","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059358967","display_name":"Barry Lynn Shulkin","orcid":"https://orcid.org/0000-0003-4784-7914","observed_orcids":["https://orcid.org/0000-0003-4784-7914"]},"institutions":[{"id":"https://openalex.org/I1313298211","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313298211","https://openalex.org/I2802152183"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Barry L Shulkin","raw_affiliation_strings":["1St Jude Children's Research Hospital,Memphis,Tennessee"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1St Jude Children's Research Hospital,Memphis,Tennessee","institution_ids":["https://openalex.org/I1313298211"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079003174","display_name":"Michael J. Gelfand","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1313298211","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313298211","https://openalex.org/I2802152183"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J Gelfand","raw_affiliation_strings":["1St Jude Children's Research Hospital,Memphis,Tennessee"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1St Jude Children's Research Hospital,Memphis,Tennessee","institution_ids":["https://openalex.org/I1313298211"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shelia Salisbury","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shelia Salisbury","raw_affiliation_strings":["2Cincinnati Children's Hospital, Cincinnati, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Cincinnati Children's Hospital, Cincinnati, Ohio","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034374604","display_name":"Wayne Lee Furman","orcid":"https://orcid.org/0000-0001-7352-3556","observed_orcids":["https://orcid.org/0000-0001-7352-3556"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wayne L Furman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8505,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.7486529,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"50","issue":"8","first_page":"1237","last_page":"43"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12226","display_name":"Neuroblastoma Research and Treatments","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12226","display_name":"Neuroblastoma Research and Treatments","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.00839999970048666,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroblastoma","display_name":"neuroblastoma","score":0.7990000247955322},{"id":"https://openalex.org/keywords/123i-mibg-scintigraphy","display_name":"123I-MIBG scintigraphy","score":0.9860000014305115},{"id":"https://openalex.org/keywords/18f-fdg-pet","display_name":"18F-FDG PET","score":0.9950000047683716},{"id":"https://openalex.org/keywords/tumor-staging","display_name":"tumor staging","score":0.6439999938011169},{"id":"https://openalex.org/keywords/metastasis-detection","display_name":"metastasis detection","score":0.675000011920929},{"id":"https://openalex.org/keywords/diagnostic-imaging-comparison","display_name":"diagnostic imaging comparison","score":0.5479999780654907}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8773380517959595},{"id":"https://openalex.org/C2776715637","wikidata":"https://www.wikidata.org/wiki/Q938205","display_name":"Neuroblastoma","level":3,"score":0.7725929617881775},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.6836103200912476},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.6703016757965088},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.535910427570343},{"id":"https://openalex.org/C2780283643","wikidata":"https://www.wikidata.org/wiki/Q2110267","display_name":"Primary tumor","level":4,"score":0.514232337474823},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4382808208465576},{"id":"https://openalex.org/C2779902710","wikidata":"https://www.wikidata.org/wiki/Q1130465","display_name":"Scintigraphy","level":2,"score":0.43826767802238464},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.34078508615493774},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2635653614997864},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.24842500686645508},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009447","descriptor_name":"Neuroblastoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019797","descriptor_name":"3-Iodobenzylguanidine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:19617326","doi":"https://doi.org/10.2967/jnumed.108.060467","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19617326","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","raw_type":"Comparative Study"},{"id":"mag:5482163","doi":null,"is_oa":false,"landing_page_url":"https://jnm.snmjournals.org/content/49/supplement_1/84P.3","pdf_url":null,"source":{"id":"https://openalex.org/S4210180780","display_name":"Journal of Nuclear Medicine","issn_l":"0161-5505","issn":["0161-5505","1535-5667","2159-662X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315767","host_organization_name":"Society of Nuclear Medicine and Molecular Imaging","host_organization_lineage":["https://openalex.org/P4310315767"],"host_organization_lineage_names":["Society of Nuclear Medicine and Molecular Imaging"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Nuclear Medicine","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.6499999761581421,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7098651555","https://openalex.org/W2132771521","https://openalex.org/W2080898936","https://openalex.org/W583016360","https://openalex.org/W2592394680","https://openalex.org/W2097004280","https://openalex.org/W2292344124","https://openalex.org/W7096111221","https://openalex.org/W1929880975","https://openalex.org/W2141078060"],"abstract_inverted_index":{"UNLABELLED:":[0],"The":[1],"purpose":[2],"of":[3,12,24,47,71,80,84,89,116,132,142,147,168,178,190,195,269,279,283],"this":[4],"study":[5],"was":[6],"to":[7,217],"compare":[8],"the":[9,257,267,280],"diagnostic":[10],"utility":[11],"(123)I-metaiodobenzylguanidine":[13],"((123)I-MIBG)":[14],"scintigraphy":[15],"and":[16,28,54,75,87,136,145,182,193,209,234,260],"(18)F-FDG":[17,29,61,76,119,137,171,183,202,221,249],"PET":[18,30],"in":[19,32,69,82,114,130,140,166,176,188,205,256,266],"neuroblastoma.":[20],"METHODS:":[21],"A":[22],"total":[23],"113":[25],"paired":[26],"(123)I-MIBG":[27,74,103,135,161,181,213,233,262],"scans":[31,41],"60":[33],"patients":[34,227],"with":[35,228],"neuroblastoma":[36,56,68,98,108,124,156,164,174],"were":[37,42,93,138,151,184,199],"retrospectively":[38],"reviewed.":[39],"Paired":[40],"acquired":[43],"within":[44],"14":[45],"days":[46],"each":[48],"other.":[49],"RESULTS:":[50],"For":[51,95,153],"stage":[52,96,154,207,270],"1":[53,83,208],"2":[55,141,210],"(13":[57],"scans,":[58,86,100,144,158,192],"10":[59,101],"patients),":[60,102,160],"depicted":[62,104,120,162,172],"more":[63,105,121,163,173],"extensive":[64,106,122],"primary":[65,107,123],"or":[66,109,111,125,127,186,246,285],"residual":[67],"9":[70],"13":[72,85,90,189],"scans.":[73,118,134,170,180],"showed":[77],"equal":[78,139],"numbers":[79],"lesions":[81],"3":[88,97],"scan":[91,149,197],"results":[92,150,198],"normal.":[94,152,200],"(15":[99],"local":[110,126],"regional":[112,128],"metastases":[113,129],"5":[115],"15":[117,133,143,148],"4":[131,146,155,271],"(85":[157],"40":[159],"sites":[165,175],"44":[167],"85":[169,179,191,196],"11":[177],"equivalent":[185],"complementary":[187],"17":[194],"CONCLUSION:":[201],"is":[203,263],"superior":[204,265],"depicting":[206],"neuroblastoma,":[211,272],"although":[212],"may":[214],"be":[215],"needed":[216],"exclude":[218],"higher-stage":[219],"disease.":[220],"also":[222,251],"provides":[223],"important":[224],"information":[225],"for":[226],"tumors":[229],"that":[230],"weakly":[231],"accumulate":[232],"at":[235],"major":[236],"decision":[237],"points":[238],"during":[239,274],"therapy":[240],"(i.e.,":[241],"before":[242,247],"stem":[243],"cell":[244],"transplantation":[245],"surgery).":[248],"can":[250],"better":[252,281],"delineate":[253],"disease":[254],"extent":[255],"chest,":[258],"abdomen,":[259],"pelvis.":[261],"overall":[264],"evaluation":[268],"especially":[273],"initial":[275],"chemotherapy,":[276],"primarily":[277],"because":[278],"detection":[282],"bone":[284],"marrow":[286],"metastases.":[287]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}