{"id":"https://openalex.org/W54678783","doi":"https://doi.org/10.1152/jn.2002.88.2.699","title":"Cisplatin-Induced Hyperactivity in the Dorsal Cochlear Nucleus and Its Relation to Outer Hair Cell Loss: Relevance to Tinnitus","display_name":"Cisplatin-Induced Hyperactivity in the Dorsal Cochlear Nucleus and Its Relation to Outer Hair Cell Loss: Relevance to Tinnitus","publication_year":2002,"publication_date":"2002-08-01","ids":{"openalex":"https://openalex.org/W54678783","doi":"https://doi.org/10.1152/jn.2002.88.2.699","mag":"54678783","pmid":"https://pubmed.ncbi.nlm.nih.gov/12163523"},"language":"en","primary_location":{"id":"doi:10.1152/jn.2002.88.2.699","doi":"https://doi.org/10.1152/jn.2002.88.2.699","is_oa":false,"landing_page_url":"https://doi.org/10.1152/jn.2002.88.2.699","pdf_url":null,"source":{"id":"https://openalex.org/S142952003","display_name":"Journal of Neurophysiology","issn_l":"0022-3077","issn":["0022-3077","1522-1598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurophysiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000235420","display_name":"James A. Kaltenbach","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James A. Kaltenbach","raw_affiliation_strings":["Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082679186","display_name":"John D. Rachel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John D. Rachel","raw_affiliation_strings":["Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077958144","display_name":"T. Alecia Mathog","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T. Alecia Mathog","raw_affiliation_strings":["Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100714820","display_name":"Jinsheng Zhang","orcid":"https://orcid.org/0000-0002-8311-2678","observed_orcids":["https://orcid.org/0000-0002-8311-2678"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jinsheng Zhang","raw_affiliation_strings":["Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048502049","display_name":"Pamela R. Falzarano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pamela R. Falzarano","raw_affiliation_strings":["Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"last","author":{"id":null,"display_name":"Matthew Lewandowski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew Lewandowski","raw_affiliation_strings":["Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201","institution_ids":["https://openalex.org/I185443292"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I185443292"],"apc_list":null,"apc_paid":null,"fwci":2.6495,"has_fulltext":false,"cited_by_count":160,"citation_normalized_percentile":{"value":0.90054127,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"88","issue":"2","first_page":"699","last_page":"714"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10542","display_name":"Vestibular and auditory disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10283","display_name":"Hearing Loss and Rehabilitation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cisplatin","display_name":"cisplatin","score":0.9049999713897705},{"id":"https://openalex.org/keywords/tinnitus","display_name":"tinnitus","score":0.9459999799728394},{"id":"https://openalex.org/keywords/dorsal-cochlear-nucleus","display_name":"dorsal cochlear nucleus","score":0.9909999966621399},{"id":"https://openalex.org/keywords/spontaneous-neuronal-activity","display_name":"spontaneous neuronal activity","score":0.7870000004768372},{"id":"https://openalex.org/keywords/hyperactivity","display_name":"hyperactivity","score":0.8479999899864197},{"id":"https://openalex.org/keywords/outer-hair-cell-loss","display_name":"outer hair cell loss","score":0.9419999718666077},{"id":"https://openalex.org/keywords/cochlear-hair-cells","display_name":"cochlear hair cells","score":0.5820000171661377},{"id":"https://openalex.org/keywords/ototoxicity","display_name":"ototoxicity","score":0.7440000176429749},{"id":"https://openalex.org/keywords/hamster","display_name":"hamster","score":0.4699999988079071}],"concepts":[{"id":"https://openalex.org/C2779091101","wikidata":"https://www.wikidata.org/wiki/Q5298771","display_name":"Dorsal cochlear nucleus","level":4,"score":0.8387068510055542},{"id":"https://openalex.org/C2776992516","wikidata":"https://www.wikidata.org/wiki/Q192309","display_name":"Tinnitus","level":2,"score":0.7562513947486877},{"id":"https://openalex.org/C33612138","wikidata":"https://www.wikidata.org/wiki/Q82654","display_name":"Tonotopy","level":3,"score":0.6315234899520874},{"id":"https://openalex.org/C2780493683","wikidata":"https://www.wikidata.org/wiki/Q16035842","display_name":"Hearing loss","level":2,"score":0.6058267951011658},{"id":"https://openalex.org/C2780130748","wikidata":"https://www.wikidata.org/wiki/Q317857","display_name":"Cochlea","level":2,"score":0.5798646807670593},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.5674357414245605},{"id":"https://openalex.org/C2778585322","wikidata":"https://www.wikidata.org/wiki/Q1566641","display_name":"Hair cell","level":3,"score":0.5570985674858093},{"id":"https://openalex.org/C2778239845","wikidata":"https://www.wikidata.org/wiki/Q412415","display_name":"Cisplatin","level":3,"score":0.5344718098640442},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.506290078163147},{"id":"https://openalex.org/C2777662796","wikidata":"https://www.wikidata.org/wiki/Q387776","display_name":"Cochlear nucleus","level":3,"score":0.439744770526886},{"id":"https://openalex.org/C2778534666","wikidata":"https://www.wikidata.org/wiki/Q1351381","display_name":"Ototoxicity","level":4,"score":0.4386724829673767},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.43478843569755554},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.43059226870536804},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.385824054479599},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.3765691816806793},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32266145944595337},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2922884523868561},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21670198440551758},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.0},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D003051","descriptor_name":"Cochlea","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014012","descriptor_name":"Tinnitus","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D014012","descriptor_name":"Tinnitus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D016923","descriptor_name":"Cell Death","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017626","descriptor_name":"Cochlear Nucleus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017626","descriptor_name":"Cochlear Nucleus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D018072","descriptor_name":"Hair Cells, Auditory, Outer","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018072","descriptor_name":"Hair Cells, Auditory, Outer","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1152/jn.2002.88.2.699","doi":"https://doi.org/10.1152/jn.2002.88.2.699","is_oa":false,"landing_page_url":"https://doi.org/10.1152/jn.2002.88.2.699","pdf_url":null,"source":{"id":"https://openalex.org/S142952003","display_name":"Journal of Neurophysiology","issn_l":"0022-3077","issn":["0022-3077","1522-1598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurophysiology","raw_type":"journal-article"},{"id":"pmid:12163523","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12163523","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurophysiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[{"id":"https://openalex.org/G852459952","display_name":null,"funder_award_id":"DC03258","funder_id":"https://openalex.org/F4320337352","funder_display_name":"National Institute on Deafness and Other Communication Disorders"}],"funders":[{"id":"https://openalex.org/F4320337352","display_name":"National Institute on Deafness and Other Communication Disorders","ror":"https://ror.org/04mhx6838"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":91,"referenced_works":["https://openalex.org/W56902722","https://openalex.org/W121179915","https://openalex.org/W139265535","https://openalex.org/W636888806","https://openalex.org/W1454570422","https://openalex.org/W1832113570","https://openalex.org/W1916238437","https://openalex.org/W1923026367","https://openalex.org/W1964937949","https://openalex.org/W1966494376","https://openalex.org/W1967886764","https://openalex.org/W1971656751","https://openalex.org/W1971801795","https://openalex.org/W1973682545","https://openalex.org/W1974980963","https://openalex.org/W1975680073","https://openalex.org/W1976439352","https://openalex.org/W1978822998","https://openalex.org/W1988784445","https://openalex.org/W1994247895","https://openalex.org/W1997632715","https://openalex.org/W2000154309","https://openalex.org/W2000203072","https://openalex.org/W2000935754","https://openalex.org/W2001107554","https://openalex.org/W2002867951","https://openalex.org/W2004561169","https://openalex.org/W2005311360","https://openalex.org/W2005999253","https://openalex.org/W2006876877","https://openalex.org/W2007506370","https://openalex.org/W2017266290","https://openalex.org/W2017786805","https://openalex.org/W2025481300","https://openalex.org/W2026579849","https://openalex.org/W2030475281","https://openalex.org/W2031001883","https://openalex.org/W2033640882","https://openalex.org/W2034646869","https://openalex.org/W2036960554","https://openalex.org/W2038004504","https://openalex.org/W2040261790","https://openalex.org/W2044233212","https://openalex.org/W2045166981","https://openalex.org/W2052343427","https://openalex.org/W2052754106","https://openalex.org/W2055796375","https://openalex.org/W2056630997","https://openalex.org/W2058890288","https://openalex.org/W2059938754","https://openalex.org/W2059998155","https://openalex.org/W2066517527","https://openalex.org/W2069201336","https://openalex.org/W2071430419","https://openalex.org/W2072577970","https://openalex.org/W2073627536","https://openalex.org/W2075050776","https://openalex.org/W2075373281","https://openalex.org/W2078381451","https://openalex.org/W2079214207","https://openalex.org/W2084059718","https://openalex.org/W2084459875","https://openalex.org/W2089114374","https://openalex.org/W2089925901","https://openalex.org/W2091194823","https://openalex.org/W2091457162","https://openalex.org/W2093708100","https://openalex.org/W2094519172","https://openalex.org/W2113683064","https://openalex.org/W2127893601","https://openalex.org/W2131040638","https://openalex.org/W2134821155","https://openalex.org/W2140215977","https://openalex.org/W2143935196","https://openalex.org/W2148773170","https://openalex.org/W2153844900","https://openalex.org/W2154422520","https://openalex.org/W2157433595","https://openalex.org/W2158592437","https://openalex.org/W2243757912","https://openalex.org/W2268765601","https://openalex.org/W2277946853","https://openalex.org/W2410842906","https://openalex.org/W2413383837","https://openalex.org/W2418032579","https://openalex.org/W2433212708","https://openalex.org/W2463352733","https://openalex.org/W2478735384","https://openalex.org/W2523753315","https://openalex.org/W4230355992","https://openalex.org/W4254786702"],"related_works":["https://openalex.org/W2148773170","https://openalex.org/W2040261790","https://openalex.org/W2165393423","https://openalex.org/W2003052230","https://openalex.org/W1488036047","https://openalex.org/W2004561169","https://openalex.org/W2084059718","https://openalex.org/W2189005084","https://openalex.org/W2395339786","https://openalex.org/W2068218991"],"abstract_inverted_index":{"Cisplatin":[0],"causes":[1],"both":[2],"acute":[3],"and":[4,72,142,238,323],"chronic":[5],"forms":[6],"of":[7,24,33,42,86,106,116,127,134,161,165,179,203,206,226,231,252,271,276,286,310,317],"tinnitus":[8],"as":[9,11],"well":[10],"increases":[12],"in":[13,18,35,61,80,171,189,198,222,268,288,294,320],"spontaneous":[14,121],"neural":[15],"activity":[16,123,166],"(hyperactivity)":[17],"the":[19,31,36,62,65,68,114,117,130,135,176,190,199,204,214,223,227,232,253,269,284,306,321],"dorsal":[20],"cochlear":[21,46],"nucleus":[22],"(DCN)":[23],"hamsters.":[25],"It":[26],"has":[27],"been":[28],"hypothesized":[29],"that":[30,153,216,256,308,325],"induction":[32],"hyperactivity":[34,71,188,194,287,319,327],"DCN":[37,118,205,270,322],"may":[38,313,328],"be":[39,314,329],"a":[40,125,146,315],"consequence":[41],"cisplatin's":[43],"effects":[44],"on":[45,113],"outer":[47],"hair":[48],"cells":[49],"(OHCs);":[50],"however,":[51],"systematic":[52],"studies":[53],"testing":[54],"this":[55,326],"hypothesis":[56],"have":[57,258],"yet":[58],"to":[59,93,119,168,245,281,334],"appear":[60],"literature.":[63],"In":[64,174,229],"present":[66],"investigation,":[67],"relationship":[69],"between":[70],"OHC":[73,184,217,236,298,311],"loss,":[74],"induced":[75,193],"by":[76,279,332],"cisplatin,":[77],"was":[78,195,211,219,241,265,291],"examined":[79],"detail.":[81],"Hamsters":[82],"received":[83],"five":[84],"treatments":[85],"cisplatin":[87],"at":[88],"doses":[89],"ranging":[90],"from":[91],"1.5":[92],"3":[94],"mg.":[95],"kg(-1).":[96],"day(-1),":[97],"every":[98],"other":[99],"day.":[100],"Beginning":[101],"1":[102],"mo":[103],"after":[104],"initiation":[105],"treatment,":[107],"electrophysiological":[108],"recordings":[109],"were":[110,140],"carried":[111],"out":[112],"surface":[115],"measure":[120],"multiunit":[122],"along":[124],"set":[126],"coordinates":[128],"spanning":[129],"medial-lateral":[131],"(tonotopic)":[132],"axis":[133],"DCN.":[136,191],"After":[137],"recordings,":[138],"cochleas":[139],"removed":[141],"studied":[143],"histologically":[144],"using":[145],"scanning":[147],"electron":[148],"microscope.":[149],"The":[150,192],"results":[151,304],"revealed":[152],"cisplatin-treated":[154,180],"animals":[155,181,233,272,290,295],"with":[156,182,213,234,260,296],"little":[157],"or":[158],"no":[159,242],"loss":[160,185,218,237,299,309],"OHCs":[162,277],"displayed":[163,186],"levels":[164],"similar":[167],"those":[169],"seen":[170,196],"saline-treated":[172],"controls.":[173],"contrast,":[175],"majority":[177],"(75%)":[178],"severe":[183,235,274,297],"well-developed":[187],"mainly":[197,221],"medial":[200],"(high-frequency)":[201],"half":[202,225],"treated":[207],"animals.":[208],"This":[209],"pattern":[210],"consistent":[212],"observation":[215],"distributed":[220],"basal":[224],"cochlea.":[228],"several":[230],"hyperactivity,":[239],"there":[240],"significant":[243],"damage":[244,280,333],"IHC":[246,262],"stereocilia":[247],"nor":[248],"any":[249],"observable":[250],"irregularities":[251],"reticular":[254],"lamina":[255],"might":[257],"interfered":[259],"normal":[261],"function.":[263],"Hyperactivity":[264],"also":[266],"observed":[267],"showing":[273],"losses":[275],"accompanied":[278],"IHCs,":[282],"although":[283],"degree":[285],"these":[289],"less":[292],"than":[293],"but":[300],"intact":[301],"IHCs.":[302,335],"These":[303],"support":[305],"view":[307],"function":[312],"trigger":[316],"tinnitus-related":[318],"suggest":[324],"somewhat":[330],"offset":[331]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":10}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}