{"id":"https://openalex.org/W54598900","doi":null,"title":"Postoperative acute adrenal failure caused by transient corticotropin deficiency.","display_name":"Postoperative acute adrenal failure caused by transient corticotropin deficiency.","publication_year":1994,"publication_date":"1994-12-01","ids":{"openalex":"https://openalex.org/W54598900","mag":"54598900","pmid":"https://pubmed.ncbi.nlm.nih.gov/7985093"},"language":"en","primary_location":{"id":"pmid:7985093","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7985093","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054953356","display_name":"W.H. Merry","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210127659","display_name":"Gundersen Lutheran Hospital","ror":"https://ror.org/03tmy2526","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1284541357","https://openalex.org/I4210127659"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W H Merry","raw_affiliation_strings":["Department of Surgery, Gundersen/Lutheran Medical Center, La Crosse, Wis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Gundersen/Lutheran Medical Center, La Crosse, Wis","institution_ids":["https://openalex.org/I4210127659"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028052828","display_name":"Robert H. Caplan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R H Caplan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060565747","display_name":"Gary G. Wickus","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G G Wickus","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043200820","display_name":"Richard H. Reynertson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R H Reynertson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078815936","display_name":"William A. Kisken","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W A Kisken","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078071180","display_name":"Thomas H. Cogbill","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T H Cogbill","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5026870426","display_name":"Jeffrey Landercasper","orcid":"https://orcid.org/0000-0002-4000-4546","observed_orcids":["https://orcid.org/0000-0002-4000-4546"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Landercasper","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0652,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.72817478,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"116","issue":"6","first_page":"1095","last_page":"100"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/postoperative-adrenal-insufficiency","display_name":"postoperative adrenal insufficiency","score":0.9369999766349792},{"id":"https://openalex.org/keywords/adrenal-crisis","display_name":"adrenal crisis","score":0.7950000166893005},{"id":"https://openalex.org/keywords/corticotropin-deficiency","display_name":"corticotropin deficiency","score":0.875},{"id":"https://openalex.org/keywords/secondary-adrenal-insufficiency","display_name":"secondary adrenal insufficiency","score":0.8529999852180481},{"id":"https://openalex.org/keywords/addison-s-disease","display_name":"Addison's disease","score":0.9319999814033508},{"id":"https://openalex.org/keywords/serum-cortisol","display_name":"serum cortisol","score":0.6499999761581421},{"id":"https://openalex.org/keywords/glucocorticoid-therapy","display_name":"glucocorticoid therapy","score":0.843999981880188},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.4740000069141388},{"id":"https://openalex.org/keywords/thyrotropin-deficiency","display_name":"thyrotropin deficiency","score":0.7850000262260437},{"id":"https://openalex.org/keywords/luteinizing-hormone-deficiency","display_name":"luteinizing hormone deficiency","score":0.8579999804496765}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9327410459518433},{"id":"https://openalex.org/C2908704050","wikidata":"https://www.wikidata.org/wiki/Q560542","display_name":"Cosyntropin","level":4,"score":0.9296287298202515},{"id":"https://openalex.org/C2778129406","wikidata":"https://www.wikidata.org/wiki/Q2507454","display_name":"Adrenal insufficiency","level":2,"score":0.8580710291862488},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5785804986953735},{"id":"https://openalex.org/C2909972456","wikidata":"https://www.wikidata.org/wiki/Q2507454","display_name":"Adrenocortical Insufficiency","level":3,"score":0.5586952567100525},{"id":"https://openalex.org/C2780841215","wikidata":"https://www.wikidata.org/wiki/Q422549","display_name":"Glucocorticoid","level":2,"score":0.5190594792366028},{"id":"https://openalex.org/C51296783","wikidata":"https://www.wikidata.org/wiki/Q1645498","display_name":"Microgram","level":3,"score":0.5159364342689514},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4856332838535309},{"id":"https://openalex.org/C2781300812","wikidata":"https://www.wikidata.org/wiki/Q178061","display_name":"Shock (circulatory)","level":2,"score":0.4815845489501953},{"id":"https://openalex.org/C2778709874","wikidata":"https://www.wikidata.org/wiki/Q190875","display_name":"Hydrocortisone","level":2,"score":0.4629533886909485},{"id":"https://openalex.org/C2780546910","wikidata":"https://www.wikidata.org/wiki/Q185690","display_name":"Adrenocorticotropic hormone","level":3,"score":0.4428200125694275},{"id":"https://openalex.org/C2911038130","wikidata":"https://www.wikidata.org/wiki/Q8282","display_name":"Primary Adrenal Insufficiency","level":3,"score":0.4317416548728943},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.41098737716674805},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3260255753993988},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000309","descriptor_name":"Adrenal Insufficiency","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006854","descriptor_name":"Hydrocortisone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D013972","descriptor_name":"Thyrotropin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:7985093","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7985093","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"Journal Article"},{"id":"mag:54598900","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7985093","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2050387233","https://openalex.org/W2413188208","https://openalex.org/W2413410245","https://openalex.org/W2133657830","https://openalex.org/W2405869600","https://openalex.org/W2033133207","https://openalex.org/W4413802071","https://openalex.org/W4234058427","https://openalex.org/W2052179488","https://openalex.org/W3153206803"],"abstract_inverted_index":{"BACKGROUND:":[0],"Acute":[1],"adrenal":[2,25,32,182,215],"insufficiency":[3,26,33],"after":[4,38,74,120],"a":[5,39],"surgical":[6,40,77],"procedure":[7,41],"or":[8,42,166,177],"trauma":[9],"is":[10,191],"rarely":[11],"reported.":[12],"In":[13,57,150],"recent":[14],"years,":[15],"however,":[16],"we":[17,60,88],"have":[18],"treated":[19],"seven":[20],"patients":[21,29,65,119,152,162,195],"with":[22,30,36,140],"acute":[23],"primary":[24],"and":[27,92,98,107,143],"three":[28],"secondary":[31,214],"who":[34,70,123],"presented":[35],"shock":[37],"trauma.":[43],"The":[44,199],"standard":[45,93,147,210],"cosyntropin":[46,96,155,202],"test":[47,203,211],"was":[48,83],"misleading":[49],"for":[50,212],"the":[51,80,172,209],"diagnosis":[52],"of":[53,117,126],"corticotropin":[54,127,189],"deficiency.":[55,169],"METHODS:":[56],"this":[58],"study":[59],"measured":[61,99],"serum":[62,81,130],"cortisol":[63,82,131,159],"in":[64,104,110,194],"older":[66],"than":[67,85,196,208],"65":[68],"years":[69],"had":[71,164],"unexplained":[72],"hypotension":[73],"an":[75,121],"abdominal":[76],"procedure.":[78],"If":[79],"less":[84],"15":[86,133],"micrograms/dl,":[87],"performed":[89],"1":[90,153,200],"microgram":[91,154,201],"(250":[94],"micrograms)":[95],"tests":[97],"thyroxine,":[100],"thyrotropin,":[101],"leutinizing":[102,167],"hormone":[103,168,174],"all":[105],"patients,":[106],"free":[108],"testosterone":[109],"men.":[111],"RESULTS:":[112],"We":[113],"identified":[114],"five":[115],"(5%)":[116],"105":[118],"operation":[122],"displayed":[124],"evidence":[125],"deficiency":[128],"(i.e.,":[129],"<":[132],"micrograms/dl":[134],"during":[135],"hypotension,":[136],"prompt":[137],"hemodynamic":[138],"improvement":[139],"glucocorticoid":[141],"therapy,":[142],"normal":[144],"response":[145],"to":[146],"dose":[148],"cosyntropin).":[149],"these":[151],"produced":[156],"abnormal":[157],"peak":[158],"levels.":[160],"These":[161],"also":[163],"thyrotropin":[165],"After":[170],"recovery":[171],"low":[173],"levels":[175],"improved":[176],"became":[178],"normal.":[179],"CONCLUSIONS:":[180],"Postoperative":[181],"insufficiency,":[183],"particularly":[184],"that":[185],"caused":[186],"by":[187],"transient":[188],"deficiency,":[190],"more":[192,206],"common":[193],"currently":[197],"recognized.":[198],"may":[204],"be":[205],"sensitive":[207],"identifying":[213],"insufficiency.":[216]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}