{"id":"https://openalex.org/W53601173","doi":null,"title":"A review of body water status and the effects of age and body fatness in children and adults.","display_name":"A review of body water status and the effects of age and body fatness in children and adults.","publication_year":2007,"publication_date":"2007-03-01","ids":{"openalex":"https://openalex.org/W53601173","mag":"53601173","pmid":"https://pubmed.ncbi.nlm.nih.gov/17435953"},"language":"en","primary_location":{"id":"pmid:17435953","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17435953","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of nutrition, health & aging","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113452598","display_name":"W. C. Chumlea","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19648265","display_name":"Wright State University","ror":"https://ror.org/04qk6pt94","country_code":"US","type":"education","lineage":["https://openalex.org/I19648265"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wm C Chumlea","raw_affiliation_strings":["Wright State University Boonshoft School of Medicine, Department of Community Health, Lifespan Health, Research Center, 3171 Research Blvd, Dayton, OH 45420, 937-775-1428, USA. cameron.chumlea@wright.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wright State University Boonshoft School of Medicine, Department of Community Health, Lifespan Health, Research Center, 3171 Research Blvd, Dayton, OH 45420, 937-775-1428, USA. cameron.chumlea@wright.edu","institution_ids":["https://openalex.org/I19648265"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113463574","display_name":"Christine M. Schubert","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C M Schubert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102019997","display_name":"Shumei S. Sun","orcid":"https://orcid.org/0000-0003-2945-4762","observed_orcids":["https://orcid.org/0000-0003-2945-4762"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S S Sun","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075195377","display_name":"Ellen W. Demerath","orcid":"https://orcid.org/0000-0002-4585-4064","observed_orcids":["https://orcid.org/0000-0002-4585-4064"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Demerath","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026845322","display_name":"Bradford Towne","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Towne","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5113576139","display_name":"R. M. Siervogel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R M Siervogel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.161,"has_fulltext":false,"cited_by_count":54,"citation_normalized_percentile":{"value":0.75316264,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"11","issue":"2","first_page":"111","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12279","display_name":"Body Composition Measurement Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12279","display_name":"Body Composition Measurement Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10010","display_name":"Obesity, Physical Activity, Diet","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11109","display_name":"Thermoregulation and physiological responses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/total-body-water","display_name":"total body water","score":0.9890000224113464},{"id":"https://openalex.org/keywords/extracellular-water","display_name":"extracellular water","score":0.9900000095367432},{"id":"https://openalex.org/keywords/body-composition","display_name":"body composition","score":0.75},{"id":"https://openalex.org/keywords/adiposity","display_name":"adiposity","score":0.7269999980926514},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.597000002861023},{"id":"https://openalex.org/keywords/fat-free-mass","display_name":"fat-free mass","score":0.7319999933242798},{"id":"https://openalex.org/keywords/age-differences","display_name":"age differences","score":0.5320000052452087},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.6190000176429749},{"id":"https://openalex.org/keywords/adults","display_name":"adults","score":0.6019999980926514},{"id":"https://openalex.org/keywords/body-water-distribution","display_name":"body water distribution","score":0.5329999923706055},{"id":"https://openalex.org/keywords/nhanes-iii","display_name":"NHANES III","score":0.781000018119812},{"id":"https://openalex.org/keywords/body-fat-estimation","display_name":"body fat estimation","score":0.45500001311302185}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8331950902938843},{"id":"https://openalex.org/C84029825","wikidata":"https://www.wikidata.org/wiki/Q4936981","display_name":"Body water","level":3,"score":0.7368971705436707},{"id":"https://openalex.org/C2780586474","wikidata":"https://www.wikidata.org/wiki/Q332428","display_name":"Overweight","level":3,"score":0.5957029461860657},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.5578685998916626},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.4356766641139984},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.4154585301876068},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4149583578109741},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.4079996347427368},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20797666907310486},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.09936490654945374},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001834","descriptor_name":"Body Water","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005006","descriptor_name":"Ethnicity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045604","descriptor_name":"Extracellular Fluid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050154","descriptor_name":"Adiposity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:17435953","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17435953","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of nutrition, health & aging","raw_type":"Journal Article"},{"id":"mag:53601173","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17435953","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G360715533","display_name":"Genetic Epidemiology of CVD Risk Factors","funder_award_id":"R01HL069995","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3945160214","display_name":"Genetic Regulation of Adiposity and Associated CVD Risks","funder_award_id":"R01DK064391","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4145764554","display_name":"Adiposity, Disease Risk Factors, and Lifetime Health","funder_award_id":"R01HD012252","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G5155956369","display_name":"Longitudinal Cardiac Outcomes and Body Composition","funder_award_id":"R01HL072838","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5962070475","display_name":"Visceral Adiposity: Genetic and Environmental Influences","funder_award_id":"R01DK064870","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G7528252063","display_name":"GENETIC EPIDEMIOLOGY OF AGING AND BODY COMPOSITION","funder_award_id":"R01AG018719","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G7728803868","display_name":"Childhood Precursors for Adulthood Metabolic Syndrome","funder_award_id":"R01DK071485","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1859790856","https://openalex.org/W2366792331","https://openalex.org/W2308059317","https://openalex.org/W4376645622","https://openalex.org/W2319030332","https://openalex.org/W1589932840","https://openalex.org/W4402823987","https://openalex.org/W1959002436","https://openalex.org/W3091983593","https://openalex.org/W366564166"],"abstract_inverted_index":{"BACKGROUND:":[0],"Most":[1],"investigations":[2],"of":[3,11,43,61,75,132,164,170,179,184,220,228,240,278,290],"TBW,":[4],"ECW":[5,23,71,188,279],"and":[6,9,22,52,70,79,83,92,122,142,174,176,214,225,252,270,272,283,295],"body":[7,27,76,81,101,241,266,291],"composition":[8,46],"reports":[10],"their":[12,73],"intra-body":[13],"relationships":[14,24,37,296],"were":[15,38],"published":[16],"prior":[17,158],"to":[18,66,159,195,211],"1980.":[19,160],"Distributional":[20],"TBW":[21,69,118,146],"within":[25],"the":[26,41,59,62,109,130,133,167,182,257,276],"have":[28],"been":[29],"considered":[30,88],"fixed,":[31],"but":[32,234],"there":[33],"was":[34],"evidence":[35],"these":[36],"affected":[39],"by":[40],"level":[42,169,178],"fatness.":[44,242],"Body":[45],"models":[47],"based":[48,222,286],"on":[49,97,223,249],"past":[50,288],"findings":[51],"assumptions":[53,289],"could":[54,230,297],"produce":[55,231,298],"inaccurate":[56,299],"estimates":[57],"when":[58],"majority":[60],"population":[63],"is":[64,245],"overweight":[65,269],"obese.":[67],"METHODS:":[68],"volumes,":[72,293],"proportions":[74,294],"weight,":[77],"FFM":[78,221],"percent":[80],"fat":[82],"associations":[84],"with":[85,129,268],"age":[86],"are":[87,124,148,193],"in":[89,172,206,265,275,280],"U.S.":[90],"children":[91,121,173],"adults.":[93],"This":[94],"review":[95],"focuses":[96],"studies":[98],"reporting":[99],"measured":[100,250],"water":[102,254,267,292],"volumes":[103,119,147,189,255],"from":[104,113,127,136],"large":[105],"samples":[106],"except":[107],"for":[108,120,139,190,256],"national":[110],"predicted":[111],"values":[112,135],"NHANES":[114,137],"III.":[115],"RESULTS:":[116],"Measured":[117],"adults":[123,192],"almost":[125],"exclusively":[126],"whites":[128],"exception":[131],"estimated":[134],"III":[138],"non-Hispanic":[140],"black":[141],"Mexican-Americans.":[143],"Mean":[144,187],"adult":[145],"as":[149,151],"much":[150],"9":[152],"liters":[153,197],"greater":[154,168,204],"than":[155,199],"those":[156,200],"reported":[157,201],"Low":[161],"mean":[162],"percentages":[163],"TBW%WT":[165],"reflect":[166],"adiposity":[171,180],"adults,":[175,207],"this":[177,215],"affects":[181],"value":[183],"TBW%":[185],"FFM.":[186],"white":[191],"10":[194],"12":[196],"larger":[198],"previously.":[202],"With":[203],"fatness":[205],"ECW%TBW":[208,227],"has":[209],"increased":[210],"near":[212],"60%,":[213],"implies":[216],"that":[217],"a":[218,262,273],"calculation":[219],"73%":[224],"an":[226,232,238],"25-45%":[229],"overestimation":[233],"more":[235],"important":[236],"clinically":[237],"underestimation":[239],"CONCLUSION:":[243],"There":[244],"inadequate":[246],"timely":[247],"information":[248],"total":[251],"extra-cellular":[253],"population.":[258],"Available":[259],"data":[260],"indicate":[261],"coincident":[263],"increase":[264],"obesity,":[271],"shifting":[274],"proportion":[277],"TBW.":[281],"Clinical":[282],"pharmacological":[284],"treatments":[285],"upon":[287],"estimates.":[300]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}