{"id":"https://openalex.org/W5279569","doi":null,"title":"The effect of ephedrine plus caffeine on plasma lipids and lipoproteins during a 4.2 MJ/day diet.","display_name":"The effect of ephedrine plus caffeine on plasma lipids and lipoproteins during a 4.2 MJ/day diet.","publication_year":1994,"publication_date":"1994-05-01","ids":{"openalex":"https://openalex.org/W5279569","mag":"5279569","pmid":"https://pubmed.ncbi.nlm.nih.gov/8061726"},"language":"en","primary_location":{"id":"pmid:8061726","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8061726","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107004534","display_name":"B Buemann","orcid":"https://orcid.org/0000-0002-8657-419X","observed_orcids":["https://orcid.org/0000-0002-8657-419X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Buemann","raw_affiliation_strings":["Research Department of Human Nutrition, Royal Veterinary and Agricultural University, Frederiksberg, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Department of Human Nutrition, Royal Veterinary and Agricultural University, Frederiksberg, Denmark","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047855759","display_name":"Peter Marckmann","orcid":"https://orcid.org/0000-0002-7458-8172","observed_orcids":["https://orcid.org/0000-0002-7458-8172"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Marckmann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113739168","display_name":"N. J. Christensen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N J Christensen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5048067129","display_name":"Arne Vernon Astrup","orcid":"https://orcid.org/0000-0001-8968-8996","observed_orcids":["https://orcid.org/0000-0001-8968-8996"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Astrup","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2704,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.51962025,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"18","issue":"5","first_page":"329","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12539","display_name":"Pharmacology and Obesity Treatment","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12539","display_name":"Pharmacology and Obesity Treatment","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts","score":0.015599999576807022,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ephedrine","display_name":"ephedrine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/caffeine","display_name":"caffeine","score":0.996999979019165},{"id":"https://openalex.org/keywords/caloric-restriction","display_name":"caloric restriction","score":0.7509999871253967},{"id":"https://openalex.org/keywords/plasma-lipids","display_name":"plasma lipids","score":0.7509999871253967},{"id":"https://openalex.org/keywords/lipoproteins","display_name":"lipoproteins","score":0.9309999942779541},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9039999842643738},{"id":"https://openalex.org/keywords/total-cholesterol","display_name":"total cholesterol","score":0.8629999756813049},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.8870000243186951},{"id":"https://openalex.org/keywords/weight-loss","display_name":"weight loss","score":0.8600000143051147},{"id":"https://openalex.org/keywords/fat-loss","display_name":"fat loss","score":0.9470000267028809},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.6259999871253967},{"id":"https://openalex.org/keywords/beta-adrenergic-agonists","display_name":"beta-adrenergic agonists","score":0.7289999723434448},{"id":"https://openalex.org/keywords/obese-women","display_name":"obese women","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C2778984665","wikidata":"https://www.wikidata.org/wiki/Q219626","display_name":"Ephedrine","level":2,"score":0.8198363184928894},{"id":"https://openalex.org/C2778500429","wikidata":"https://www.wikidata.org/wiki/Q60235","display_name":"Caffeine","level":2,"score":0.7577967643737793},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7333567142486572},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7256053686141968},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.718496561050415},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.6970920562744141},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.6648788452148438},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.5942399501800537},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46556758880615234},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3959096670150757},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.3642997145652771},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.13973981142044067},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002110","descriptor_name":"Caffeine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002110","descriptor_name":"Caffeine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004038","descriptor_name":"Diet, Reducing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004809","descriptor_name":"Ephedrine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004809","descriptor_name":"Ephedrine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008076","descriptor_name":"Cholesterol, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D013006","descriptor_name":"Growth Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015431","descriptor_name":"Weight Loss","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:8061726","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8061726","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity","raw_type":"Clinical Trial"},{"id":"mag:5279569","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8061726","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2290920852","https://openalex.org/W111275053","https://openalex.org/W2133101055","https://openalex.org/W67149165","https://openalex.org/W3501369","https://openalex.org/W2331366182","https://openalex.org/W36044457","https://openalex.org/W2075830334","https://openalex.org/W3216627833","https://openalex.org/W2157583412"],"abstract_inverted_index":{"The":[0],"effect":[1,124],"of":[2,7,58,125,169],"treatment":[3],"with":[4,86],"a":[5,138],"combination":[6],"ephedrine":[8,36],"and":[9,56,106],"caffeine":[10,40],"during":[11,160],"eight":[12],"weeks'":[13],"energy":[14],"restriction":[15],"(4.2":[16],"MJ/day)":[17],"on":[18,129],"the":[19,70,91,110,120,134,143,156,166],"fasting":[20],"plasma":[21,130],"lipid":[22],"profile":[23],"was":[24,96,127,140],"studied":[25],"in":[26,109,119,133,142,158],"obese":[27],"women.":[28],"Thirty-two":[29],"women":[30],"were":[31],"randomly":[32],"assigned":[33],"to":[34,79,165],"either":[35],"20":[37],"mg":[38,42],"plus":[39],"200":[41],"(EC)":[43],"or":[44],"placebo":[45,111,135],"three":[46],"times":[47],"per":[48],"day.":[49],"Weight":[50],"loss":[51,57,163],"(7.8":[52],"+/-":[53,62,83,100],"0.63":[54],"kg)":[55,64],"fat":[59],"mass":[60],"(6.2":[61],"0.49":[63],"did":[65],"not":[66],"differ":[67],"significantly":[68],"between":[69,90],"two":[71,92],"groups.":[72,93],"Total":[73],"cholesterol":[74],"concentration":[75,95,132],"declined":[76],"from":[77],"baseline":[78],"week":[80,104,107,147],"8":[81,108],"(0.58":[82],"0.13":[84],"mmol/l)":[85],"no":[87],"significant":[88],"difference":[89],"HDL-cholesterol":[94,159],"decreased":[97],"by":[98],"0.14":[99],"0.03":[101],"mmol/l":[102],"at":[103,146],"4":[105],"group":[112,136,145],"(P":[113],"<":[114],"0.05)":[115],"but":[116,137],"remained":[117],"unchanged":[118],"EC":[121,144,153],"group.":[122],"No":[123],"dieting":[126],"seen":[128],"triglyceride":[131],"decrease":[139],"observed":[141],"8.":[148],"It":[149],"is":[150],"suggested":[151],"that":[152],"combinations":[154],"abolish":[155],"decline":[157],"active":[161],"weight":[162],"due":[164],"beta-agonistic":[167],"properties":[168],"ephedrine.":[170]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}