{"id":"https://openalex.org/W5279327","doi":null,"title":"Stimulus response coupling in the carotid body: a role for metabolic signalling","display_name":"Stimulus response coupling in the carotid body: a role for metabolic signalling","publication_year":2013,"publication_date":"2013-07-01","ids":{"openalex":"https://openalex.org/W5279327","mag":"5279327"},"language":"en","primary_location":{"id":"pmh:oai:etheses.bham.ac.uk:4192","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/4192/1/Holmes13PhD.pdf","pdf_url":"http://etheses.bham.ac.uk/4192/1/Holmes13PhD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://etheses.bham.ac.uk/4192/1/Holmes13PhD.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005046951","display_name":"Andrew P. Holmes","orcid":"https://orcid.org/0000-0001-9270-9401","observed_orcids":["https://orcid.org/0000-0001-9270-9401"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Andrew P. Holmes","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9270-9401","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5005046951"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carotid-body","display_name":"carotid body","score":1.0},{"id":"https://openalex.org/keywords/hypoxia","display_name":"hypoxia","score":0.8880000114440918},{"id":"https://openalex.org/keywords/metabolic-signalling","display_name":"metabolic signalling","score":0.6980000138282776},{"id":"https://openalex.org/keywords/mitochondrial-bioenergetics","display_name":"mitochondrial bioenergetics","score":0.9129999876022339},{"id":"https://openalex.org/keywords/glucose-deprivation","display_name":"glucose deprivation","score":0.9330000281333923},{"id":"https://openalex.org/keywords/glycogen-metabolism","display_name":"glycogen metabolism","score":0.9710000157356262},{"id":"https://openalex.org/keywords/adenosine","display_name":"adenosine","score":0.9369999766349792},{"id":"https://openalex.org/keywords/neuromodulation","display_name":"neuromodulation","score":0.8270000219345093},{"id":"https://openalex.org/keywords/respiratory-reflexes","display_name":"respiratory reflexes","score":0.503000020980835},{"id":"https://openalex.org/keywords/cardiopulmonary-disease","display_name":"cardiopulmonary disease","score":0.8820000290870667}],"concepts":[{"id":"https://openalex.org/C2778113364","wikidata":"https://www.wikidata.org/wiki/Q1532008","display_name":"Carotid body","level":3,"score":0.6472078561782837},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.6034706830978394},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.5075737237930298},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4915975034236908},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4534017741680145},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4501233398914337},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.43864336609840393},{"id":"https://openalex.org/C2779918689","wikidata":"https://www.wikidata.org/wiki/Q3771842","display_name":"Stimulus (psychology)","level":2,"score":0.43052002787590027},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4080731272697449},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35567349195480347},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2603170871734619},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.11066043376922607},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:etheses.bham.ac.uk:4192","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/4192/1/Holmes13PhD.pdf","pdf_url":"http://etheses.bham.ac.uk/4192/1/Holmes13PhD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"pmh:oai:uilis.unsyiah.ac.id:58888","doi":null,"is_oa":true,"landing_page_url":"http://uilis.unsyiah.ac.id/opentheses/items/show/58888","pdf_url":"http://uilis.unsyiah.ac.id/opentheses/items/show/58888","source":{"id":"https://openalex.org/S4377196378","display_name":"UPT. Syiah Kuala University Library (Syiah Kuala University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187494767","host_organization_name":"Universitas Syiah Kuala","host_organization_lineage":["https://openalex.org/I187494767"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:5279327","doi":null,"is_oa":false,"landing_page_url":"http://etheses.bham.ac.uk/4192/1/Holmes13PhD.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:etheses.bham.ac.uk:4192","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/4192/1/Holmes13PhD.pdf","pdf_url":"http://etheses.bham.ac.uk/4192/1/Holmes13PhD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320339","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W5279327.pdf","grobid_xml":"https://content.openalex.org/works/W5279327.grobid-xml"},"referenced_works_count":390,"referenced_works":["https://openalex.org/W8515037","https://openalex.org/W20224721","https://openalex.org/W90732631","https://openalex.org/W147389121","https://openalex.org/W177097277","https://openalex.org/W184164879","https://openalex.org/W200203716","https://openalex.org/W589402727","https://openalex.org/W1492017050","https://openalex.org/W1504646568","https://openalex.org/W1512074319","https://openalex.org/W1526357026","https://openalex.org/W1527062564","https://openalex.org/W1528220495","https://openalex.org/W1536619169","https://openalex.org/W1545421197","https://openalex.org/W1560802690","https://openalex.org/W1561624774","https://openalex.org/W1562098826","https://openalex.org/W1568357466","https://openalex.org/W1580575515","https://openalex.org/W1586219596","https://openalex.org/W1593537432","https://openalex.org/W1744173909","https://openalex.org/W1789910835","https://openalex.org/W1824296425","https://openalex.org/W1850822705","https://openalex.org/W1858776810","https://openalex.org/W1880484442","https://openalex.org/W1891751615","https://openalex.org/W1900961504","https://openalex.org/W1913661755","https://openalex.org/W1963555278","https://openalex.org/W1964058612","https://openalex.org/W1964320031","https://openalex.org/W1966475752","https://openalex.org/W1966607171","https://openalex.org/W1966706887","https://openalex.org/W1968885616","https://openalex.org/W1969053875","https://openalex.org/W1969232036","https://openalex.org/W1969489400","https://openalex.org/W1970225649","https://openalex.org/W1970572439","https://openalex.org/W1971183383","https://openalex.org/W1972205940","https://openalex.org/W1973300372","https://openalex.org/W1973510703","https://openalex.org/W1973637907","https://openalex.org/W1974669825","https://openalex.org/W1974870493","https://openalex.org/W1976217538","https://openalex.org/W1976399922","https://openalex.org/W1977473423","https://openalex.org/W1978301872","https://openalex.org/W1978763812","https://openalex.org/W1978938889","https://openalex.org/W1979033680","https://openalex.org/W1980047913","https://openalex.org/W1980114985","https://openalex.org/W1980739152","https://openalex.org/W1980815873","https://openalex.org/W1982030800","https://openalex.org/W1983905487","https://openalex.org/W1984055521","https://openalex.org/W1985026594","https://openalex.org/W1987095470","https://openalex.org/W1987326893","https://openalex.org/W1988875133","https://openalex.org/W1988884715","https://openalex.org/W1990278643","https://openalex.org/W1990363153","https://openalex.org/W1990988256","https://openalex.org/W1991463589","https://openalex.org/W1992362833","https://openalex.org/W1992553177","https://openalex.org/W1992686674","https://openalex.org/W1993148572","https://openalex.org/W1993633986","https://openalex.org/W1994041994","https://openalex.org/W1995335718","https://openalex.org/W1995437664","https://openalex.org/W1995731325","https://openalex.org/W1996459115","https://openalex.org/W1996713672","https://openalex.org/W1996906985","https://openalex.org/W1997583884","https://openalex.org/W1998505516","https://openalex.org/W1998939044","https://openalex.org/W1999675865","https://openalex.org/W2000028741","https://openalex.org/W2000160678","https://openalex.org/W2001000107","https://openalex.org/W2002999036","https://openalex.org/W2003660947","https://openalex.org/W2003947350","https://openalex.org/W2005110301","https://openalex.org/W2006560929","https://openalex.org/W2006598620","https://openalex.org/W2006774640","https://openalex.org/W2006964476","https://openalex.org/W2008201498","https://openalex.org/W2008346798","https://openalex.org/W2009078172","https://openalex.org/W2009506694","https://openalex.org/W2011393189","https://openalex.org/W2012903526","https://openalex.org/W2013075447","https://openalex.org/W2014292100","https://openalex.org/W2014670133","https://openalex.org/W2015463169","https://openalex.org/W2016249568","https://openalex.org/W2017907872","https://openalex.org/W2018016689","https://openalex.org/W2018205667","https://openalex.org/W2018485343","https://openalex.org/W2019315506","https://openalex.org/W2019332869","https://openalex.org/W2020079132","https://openalex.org/W2020088210","https://openalex.org/W2020358342","https://openalex.org/W2020855492","https://openalex.org/W2021017307","https://openalex.org/W2021861734","https://openalex.org/W2021925516","https://openalex.org/W2022424814","https://openalex.org/W2022997798","https://openalex.org/W2023384807","https://openalex.org/W2023629143","https://openalex.org/W2025704372","https://openalex.org/W2027048243","https://openalex.org/W2027512930","https://openalex.org/W2027685228","https://openalex.org/W2028286745","https://openalex.org/W2028553047","https://openalex.org/W2028717822","https://openalex.org/W2028863158","https://openalex.org/W2030636484","https://openalex.org/W2031374244","https://openalex.org/W2031630739","https://openalex.org/W2031755372","https://openalex.org/W2031923131","https://openalex.org/W2032411573","https://openalex.org/W2033357754","https://openalex.org/W2033497590","https://openalex.org/W2033791434","https://openalex.org/W2033830908","https://openalex.org/W2036305202","https://openalex.org/W2036441257","https://openalex.org/W2036766356","https://openalex.org/W2036829402","https://openalex.org/W2036962855","https://openalex.org/W2037426474","https://openalex.org/W2037748911","https://openalex.org/W2039979152","https://openalex.org/W2040328845","https://openalex.org/W2041050549","https://openalex.org/W2041634756","https://openalex.org/W2042422091","https://openalex.org/W2042446277","https://openalex.org/W2043403270","https://openalex.org/W2044041417","https://openalex.org/W2044709180","https://openalex.org/W2044737129","https://openalex.org/W2044871388","https://openalex.org/W2045702655","https://openalex.org/W2046133716","https://openalex.org/W2046321352","https://openalex.org/W2047545717","https://openalex.org/W2047595976","https://openalex.org/W2048201868","https://openalex.org/W2048623726","https://openalex.org/W2048870600","https://openalex.org/W2048900931","https://openalex.org/W2049483576","https://openalex.org/W2049860782","https://openalex.org/W2050344897","https://openalex.org/W2050357506","https://openalex.org/W2051892537","https://openalex.org/W2052371796","https://openalex.org/W2052749003","https://openalex.org/W2053011922","https://openalex.org/W2053095249","https://openalex.org/W2053195761","https://openalex.org/W2053269045","https://openalex.org/W2054704723","https://openalex.org/W2054710495","https://openalex.org/W2055799029","https://openalex.org/W2057808940","https://openalex.org/W2057998788","https://openalex.org/W2058093835","https://openalex.org/W2058818025","https://openalex.org/W2059576421","https://openalex.org/W2059920352","https://openalex.org/W2060727108","https://openalex.org/W2061513669","https://openalex.org/W2063093688","https://openalex.org/W2065249636","https://openalex.org/W2067522487","https://openalex.org/W2067979493","https://openalex.org/W2068027702","https://openalex.org/W2068063361","https://openalex.org/W2068275163","https://openalex.org/W2068474073","https://openalex.org/W2068628705","https://openalex.org/W2068910243","https://openalex.org/W2069728361","https://openalex.org/W2070102839","https://openalex.org/W2070232301","https://openalex.org/W2070910260","https://openalex.org/W2073345848","https://openalex.org/W2073618740","https://openalex.org/W2074007285","https://openalex.org/W2074214422","https://openalex.org/W2074351642","https://openalex.org/W2075156030","https://openalex.org/W2075366948","https://openalex.org/W2076510866","https://openalex.org/W2076551952","https://openalex.org/W2077214593","https://openalex.org/W2078178926","https://openalex.org/W2078324060","https://openalex.org/W2078509049","https://openalex.org/W2079213411","https://openalex.org/W2079227077","https://openalex.org/W2080128777","https://openalex.org/W2080578842","https://openalex.org/W2080627140","https://openalex.org/W2082177070","https://openalex.org/W2083808836","https://openalex.org/W2083809966","https://openalex.org/W2084570418","https://openalex.org/W2085472665","https://openalex.org/W2086676754","https://openalex.org/W2086689426","https://openalex.org/W2087004550","https://openalex.org/W2087911936","https://openalex.org/W2088239014","https://openalex.org/W2088252120","https://openalex.org/W2088440522","https://openalex.org/W2090351704","https://openalex.org/W2090566779","https://openalex.org/W2091268562","https://openalex.org/W2091306376","https://openalex.org/W2092390663","https://openalex.org/W2092510134","https://openalex.org/W2092544150","https://openalex.org/W2093388651","https://openalex.org/W2093889998","https://openalex.org/W2095755999","https://openalex.org/W2095893583","https://openalex.org/W2096118264","https://openalex.org/W2097099406","https://openalex.org/W2098453482","https://openalex.org/W2099782420","https://openalex.org/W2100288030","https://openalex.org/W2100781232","https://openalex.org/W2102223905","https://openalex.org/W2102891343","https://openalex.org/W2103939721","https://openalex.org/W2104194825","https://openalex.org/W2104467794","https://openalex.org/W2105900110","https://openalex.org/W2106324494","https://openalex.org/W2106659867","https://openalex.org/W2106838679","https://openalex.org/W2107522886","https://openalex.org/W2110040640","https://openalex.org/W2111056062","https://openalex.org/W2112007824","https://openalex.org/W2112331117","https://openalex.org/W2113065956","https://openalex.org/W2113620884","https://openalex.org/W2114952735","https://openalex.org/W2115274363","https://openalex.org/W2116365398","https://openalex.org/W2116376555","https://openalex.org/W2116603854","https://openalex.org/W2116948662","https://openalex.org/W2119711962","https://openalex.org/W2119727059","https://openalex.org/W2120311544","https://openalex.org/W2120714892","https://openalex.org/W2121315957","https://openalex.org/W2122533794","https://openalex.org/W2122725744","https://openalex.org/W2124022771","https://openalex.org/W2124451529","https://openalex.org/W2124536446","https://openalex.org/W2124737580","https://openalex.org/W2124920380","https://openalex.org/W2125916741","https://openalex.org/W2125953019","https://openalex.org/W2127031045","https://openalex.org/W2127192155","https://openalex.org/W2127224156","https://openalex.org/W2129057950","https://openalex.org/W2130019684","https://openalex.org/W2130400779","https://openalex.org/W2130770984","https://openalex.org/W2131648558","https://openalex.org/W2132377842","https://openalex.org/W2133479500","https://openalex.org/W2134175058","https://openalex.org/W2135806640","https://openalex.org/W2137992270","https://openalex.org/W2138011583","https://openalex.org/W2138226825","https://openalex.org/W2138319716","https://openalex.org/W2138340725","https://openalex.org/W2138598651","https://openalex.org/W2138709499","https://openalex.org/W2138956994","https://openalex.org/W2139490991","https://openalex.org/W2139704316","https://openalex.org/W2140058549","https://openalex.org/W2140432562","https://openalex.org/W2140664776","https://openalex.org/W2141174309","https://openalex.org/W2141260882","https://openalex.org/W2141835651","https://openalex.org/W2141852739","https://openalex.org/W2142784061","https://openalex.org/W2143540423","https://openalex.org/W2145530136","https://openalex.org/W2146041732","https://openalex.org/W2147949152","https://openalex.org/W2147993424","https://openalex.org/W2148072839","https://openalex.org/W2148601598","https://openalex.org/W2149980494","https://openalex.org/W2151913862","https://openalex.org/W2153376781","https://openalex.org/W2153416196","https://openalex.org/W2154628078","https://openalex.org/W2155481474","https://openalex.org/W2156587759","https://openalex.org/W2157253654","https://openalex.org/W2157849239","https://openalex.org/W2158124791","https://openalex.org/W2158197357","https://openalex.org/W2158787215","https://openalex.org/W2158802782","https://openalex.org/W2159310780","https://openalex.org/W2159620999","https://openalex.org/W2160005411","https://openalex.org/W2160806878","https://openalex.org/W2161480852","https://openalex.org/W2163092377","https://openalex.org/W2163466069","https://openalex.org/W2163983650","https://openalex.org/W2165218367","https://openalex.org/W2166714586","https://openalex.org/W2168547726","https://openalex.org/W2168761712","https://openalex.org/W2169117289","https://openalex.org/W2171648839","https://openalex.org/W2215702250","https://openalex.org/W2216173657","https://openalex.org/W2229936737","https://openalex.org/W2236315019","https://openalex.org/W2245668509","https://openalex.org/W2255076808","https://openalex.org/W2260129756","https://openalex.org/W2264784497","https://openalex.org/W2268005092","https://openalex.org/W2268662053","https://openalex.org/W2270917078","https://openalex.org/W2275333482","https://openalex.org/W2278292778","https://openalex.org/W2286574444","https://openalex.org/W2299692056","https://openalex.org/W2313758577","https://openalex.org/W2316838121","https://openalex.org/W2333343699","https://openalex.org/W2335449614","https://openalex.org/W2394867512","https://openalex.org/W2407527155","https://openalex.org/W2409926494","https://openalex.org/W2413669248","https://openalex.org/W2414388451","https://openalex.org/W2415054248","https://openalex.org/W2416137082","https://openalex.org/W2417777551","https://openalex.org/W2432349214","https://openalex.org/W2440203661","https://openalex.org/W2466590699","https://openalex.org/W2472099219","https://openalex.org/W2575137241","https://openalex.org/W2785563066"],"related_works":["https://openalex.org/W2747095934","https://openalex.org/W1516745984","https://openalex.org/W2799937394","https://openalex.org/W2120311544","https://openalex.org/W2151195490","https://openalex.org/W7099344345","https://openalex.org/W2226618432","https://openalex.org/W2288382560","https://openalex.org/W2771963480","https://openalex.org/W2980325027"],"abstract_inverted_index":{"The":[0],"mammalian":[1],"carotid":[2],"body":[3],"(CB)":[4],"is":[5,91,100,146],"the":[6,21,47,58,73,77,83,95,113,127,135,144],"primary":[7],"sensory":[8],"organ":[9],"that":[10,39,94,143,154],"responds":[11],"to":[12,41,81,98,132,150],"a":[13,30,63,101,104,182],"reduction":[14,105],"in":[15,57,85,106,139,159,196],"arterial":[16],"O\\\\(_2\\\\)":[17,44],"tension.":[18],"Activation":[19],"of":[20,25,32,62,65,75,103,112,164,194],"CB":[22,54,84,96,145],"and":[23,36,60,110,153,175],"stimulation":[24,111],"its":[26],"chemoafferent":[27,55,168,198],"fibres":[28],"evokes":[29],"series":[31],"well":[33],"characterised":[34],"cardiovascular":[35],"respiratory":[37],"reflexes":[38],"act":[40],"restore":[42],"normal":[43],"levels":[45],"throughout":[46],"organism.":[48],"A":[49],"role":[50,187],"for":[51,129,188],"an":[52],"elevated":[53],"outflow":[56,169],"aetiology":[59],"progression":[61],"number":[64],"cardiorespiratory":[66],"disease":[67],"states":[68],"has":[69],"been":[70],"identified,":[71],"underlying":[72],"importance":[74],"understanding":[76],"signalling":[78,121],"mechanisms":[79],"required":[80],"activate":[82],"hypoxia.":[86],"In":[87],"this":[88,140],"thesis":[89,180],"evidence":[90],"provided":[92],"indicating":[93],"response":[97],"hypoxia":[99],"consequence":[102],"mitochondrial":[107],"energy":[108,157],"metabolism":[109,163],"liver":[114],"kinase":[115,120],"B":[116],"1/AMP":[117],"activated":[118],"protein":[119],"cascade.":[122],"Questions":[123],"also":[124],"remain":[125],"over":[126],"potential":[128],"other":[130],"stimuli":[131],"acutely":[133],"stimulate":[134],"CB.":[136],"Observations":[137],"described":[138],"investigation":[141],"suggest":[142],"not":[147],"directly":[148],"sensitive":[149],"glucose":[151],"deprivation":[152],"it":[155],"preserves":[156],"status":[158],"these":[160],"conditions":[161],"by":[162],"stored":[165],"glycogen.":[166],"Finally,":[167],"is,":[170],"ultimately,":[171],"dependent":[172],"upon":[173],"neurotransmission":[174],"small":[176],"molecule":[177],"neuromodulation.":[178],"This":[179],"demonstrates":[181],"previously":[183],"uncharacterised":[184],"key":[185],"functional":[186],"adenosine":[189],"derived":[190],"from":[191],"extracellular":[192],"catabolism":[193],"ATP":[195],"mediating":[197],"activity.":[199]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
