{"id":"https://openalex.org/W52424167","doi":"https://doi.org/10.1093/oxfordjournals.jbchem.a122762","title":"Studies on the Sugar Chains of Interferon-\u03b3 from Human Peripheral-Blood Lymphocytes1","display_name":"Studies on the Sugar Chains of Interferon-\u03b3 from Human Peripheral-Blood Lymphocytes1","publication_year":1989,"publication_date":"1989-06-01","ids":{"openalex":"https://openalex.org/W52424167","doi":"https://doi.org/10.1093/oxfordjournals.jbchem.a122762","mag":"52424167","pmid":"https://pubmed.ncbi.nlm.nih.gov/2504704"},"language":"en","primary_location":{"id":"doi:10.1093/oxfordjournals.jbchem.a122762","doi":"https://doi.org/10.1093/oxfordjournals.jbchem.a122762","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oxfordjournals.jbchem.a122762","pdf_url":null,"source":{"id":"https://openalex.org/S184547178","display_name":"The Journal of Biochemistry","issn_l":"0021-924X","issn":["0021-924X","1756-2651"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101539127","display_name":"Shigeto Yamamoto","orcid":"https://orcid.org/0000-0002-1456-8794","observed_orcids":["https://orcid.org/0000-0002-1456-8794"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeto Yamamoto","raw_affiliation_strings":["Department of Chemistry, Osaka University College of Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Osaka University College of Science","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111512948","display_name":"Sumihiro Hase","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Sumihiro Hase","raw_affiliation_strings":["Department of Chemistry, Osaka University College of Science Toyonaka, Osaka 560"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Osaka University College of Science Toyonaka, Osaka 560","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hiroshi Yamauchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210104993","display_name":"Hayashibara (Japan)","ror":"https://ror.org/01rvpy991","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210104993"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Yamauchi","raw_affiliation_strings":["Hayashibara Biochemical Lab. Inc. Okayama, Okayama 700"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hayashibara Biochemical Lab. Inc. Okayama, Okayama 700","institution_ids":["https://openalex.org/I4210104993"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110404737","display_name":"Tadao Tanimoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210104993","display_name":"Hayashibara (Japan)","ror":"https://ror.org/01rvpy991","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210104993"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tadao Tanimoto","raw_affiliation_strings":["Hayashibara Biochemical Lab. Inc. Okayama, Okayama 700"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hayashibara Biochemical Lab. Inc. Okayama, Okayama 700","institution_ids":["https://openalex.org/I4210104993"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088909164","display_name":"Tokuji Ikenaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tokuji Ikenaka","raw_affiliation_strings":["Department of Chemistry, Osaka University College of Science Toyonaka, Osaka 560"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Osaka University College of Science Toyonaka, Osaka 560","institution_ids":["https://openalex.org/I98285908"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5111512948"],"corresponding_institution_ids":["https://openalex.org/I98285908"],"apc_list":{"value":3276,"currency":"USD","value_usd":3276},"apc_paid":null,"fwci":0.4307,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.53415997,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"105","issue":"6","first_page":"1034","last_page":"1039"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.9980000257492065},{"id":"https://openalex.org/keywords/glycosylation","display_name":"glycosylation","score":0.7160000205039978},{"id":"https://openalex.org/keywords/sugar-chains","display_name":"sugar chains","score":0.6320000290870667},{"id":"https://openalex.org/keywords/peripheral-blood-lymphocytes","display_name":"peripheral blood lymphocytes","score":0.8090000152587891},{"id":"https://openalex.org/keywords/sialic-acid","display_name":"sialic acid","score":0.7480000257492065},{"id":"https://openalex.org/keywords/n-acetylneuraminic-acid","display_name":"N-acetylneuraminic acid","score":0.8190000057220459},{"id":"https://openalex.org/keywords/fucose","display_name":"fucose","score":0.7580000162124634},{"id":"https://openalex.org/keywords/biantennary-glycans","display_name":"biantennary glycans","score":0.6499999761581421},{"id":"https://openalex.org/keywords/glycan-structure","display_name":"glycan structure","score":0.6729999780654907},{"id":"https://openalex.org/keywords/desialylation","display_name":"desialylation","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7985442876815796},{"id":"https://openalex.org/C73826308","wikidata":"https://www.wikidata.org/wiki/Q684907","display_name":"Elution","level":2,"score":0.6614768505096436},{"id":"https://openalex.org/C2777108408","wikidata":"https://www.wikidata.org/wiki/Q11002","display_name":"Sugar","level":2,"score":0.6381599307060242},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5906683206558228},{"id":"https://openalex.org/C97428945","wikidata":"https://www.wikidata.org/wiki/Q15305109","display_name":"Fractionation","level":2,"score":0.563595175743103},{"id":"https://openalex.org/C193363816","wikidata":"https://www.wikidata.org/wiki/Q1617865","display_name":"Size-exclusion chromatography","level":3,"score":0.5273512005805969},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.4925699830055237},{"id":"https://openalex.org/C119157956","wikidata":"https://www.wikidata.org/wiki/Q796604","display_name":"Acetylation","level":3,"score":0.4297976791858673},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.42805057764053345},{"id":"https://openalex.org/C2909179924","wikidata":"https://www.wikidata.org/wiki/Q6046488","display_name":"Alpha interferon","level":3,"score":0.4255140721797943},{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.3336431384086609},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1023716926574707},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.09748724102973938},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002241","descriptor_name":"Carbohydrates","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002852","descriptor_name":"Chromatography, Ion Exchange","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006868","descriptor_name":"Hydrolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009439","descriptor_name":"Neuraminidase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012794","descriptor_name":"Sialic Acids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/oxfordjournals.jbchem.a122762","doi":"https://doi.org/10.1093/oxfordjournals.jbchem.a122762","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oxfordjournals.jbchem.a122762","pdf_url":null,"source":{"id":"https://openalex.org/S184547178","display_name":"The Journal of Biochemistry","issn_l":"0021-924X","issn":["0021-924X","1756-2651"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Biochemistry","raw_type":"journal-article"},{"id":"pmid:2504704","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2504704","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4043000042438507}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1936498676","https://openalex.org/W1579840516","https://openalex.org/W2095428324","https://openalex.org/W2167054990","https://openalex.org/W1969519053","https://openalex.org/W2132801999","https://openalex.org/W2091398768","https://openalex.org/W1505004647","https://openalex.org/W2114041574","https://openalex.org/W2588189599"],"abstract_inverted_index":{"Sugar":[0],"chains":[1,23,44,71],"of":[2,20,49,69,72,96,119],"interferon-gamma":[3],"(IFN-gamma)":[4],"from":[5,74],"human":[6,76],"peripheral-blood":[7],"lymphocytes":[8],"(PBL)":[9,108],"were":[10,24,33,45],"liberated":[11],"by":[12,35,55,94],"hydrazinolysis.":[13],"After":[14],"N-acetylation,":[15],"the":[16,21,29,75,128],"reducing":[17],"end":[18],"residues":[19],"sugar":[22],"tagged":[25],"with":[26,67,114],"2-aminopyridine":[27],"and":[28,38,64,92,111,147],"pyridylamino":[30],"(PA-)":[31],"derivatives":[32],"purified":[34],"gel":[36],"filtration":[37],"reversed-phase":[39],"HPLC.":[40],"Five":[41],"major":[42],"PA-sugar":[43,51,70],"obtained.":[46],"The":[47,103],"structure":[48],"each":[50],"chain":[52],"was":[53,133],"estimated":[54],"comparing":[56],"its":[57],"elution":[58,98],"times":[59,99],"on":[60],"anion":[61],"exchange,":[62],"reversed-phase,":[63],"size-fractionation":[65],"HPLC":[66],"those":[68],"IFN-gamma":[73,107,125,136,139],"myelomonocyte":[77],"cell":[78],"line":[79],"HBL-38":[80],"(Yamamoto,":[81],"S.":[82],"et":[83],"al.":[84],"(1989)":[85],"J.":[86],"Biochem.":[87],"105,":[88],"547-555)":[89],"as":[90,122],"standards,":[91],"also":[93],"comparison":[95],"their":[97],"after":[100],"partial":[101],"desialylation.":[102],"results":[104],"showed":[105],"that":[106],"contained":[109],"mono-":[110],"disialo-biantennary":[112],"structures":[113],"0":[115],"or":[116],"1":[117],"mol":[118],"fucose":[120],"residue,":[121],"found":[123],"for":[124],"(HBL-38),":[126,140],"but":[127],"N-acetylneuraminyl":[129,144],"alpha":[130,145,148],"2-6":[131,149],"linkage":[132],"dominant":[134],"in":[135],"(PBL),":[137],"unlike":[138],"which":[141],"contains":[142],"both":[143],"2-3":[146],"linkages.":[150]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}