{"id":"https://openalex.org/W5193830","doi":null,"title":"Abstract 16932: Melatonin Inhibits Large Conductance, Calcium-Activated K Channel Activity in Porcine Coronary Artery Smooth Muscle Cells by Activating MT2-Receptors","display_name":"Abstract 16932: Melatonin Inhibits Large Conductance, Calcium-Activated K Channel Activity in Porcine Coronary Artery Smooth Muscle Cells by Activating MT2-Receptors","publication_year":2011,"publication_date":"2011-11-22","ids":{"openalex":"https://openalex.org/W5193830","mag":"5193830"},"language":"en","primary_location":{"id":"mag:5193830","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/10.1161/circ.124.suppl_21.A16932","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null},"volume":null,"type":"conference-abstract","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036475364","display_name":"Praveen Shukla","orcid":"https://orcid.org/0000-0002-9675-9585","observed_orcids":["https://orcid.org/0000-0002-9675-9585"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Praveen Shukla","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9675-9585","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047397003","display_name":"Fanrong Yao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fanrong Yao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026126544","display_name":"Pawel P. Borowicz","orcid":"https://orcid.org/0000-0002-5604-5844","observed_orcids":["https://orcid.org/0000-0002-5604-5844"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pawel P. Borowicz","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5604-5844","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008684466","display_name":"Chengwen Sun","orcid":"https://orcid.org/0000-0001-5889-8448","observed_orcids":["https://orcid.org/0000-0001-5889-8448"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chengwen Sun","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5889-8448","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5024393450","display_name":"Stephen T. O\u2019Rourke","orcid":"https://orcid.org/0000-0002-5438-7816","observed_orcids":["https://orcid.org/0000-0002-5438-7816"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephen T. O\u2019Rourke","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5438-7816","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"124","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.04520000144839287,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.009100000374019146,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/melatonin","display_name":"melatonin","score":1.0},{"id":"https://openalex.org/keywords/bk-channels","display_name":"BK channels","score":0.9359999895095825},{"id":"https://openalex.org/keywords/bkca-channels","display_name":"BKCa channels","score":0.7440000176429749},{"id":"https://openalex.org/keywords/mt2-melatonin-receptor","display_name":"MT2 receptor","score":0.9210000038146973},{"id":"https://openalex.org/keywords/coronary-artery-smooth-muscle-cells","display_name":"coronary artery smooth muscle cells","score":0.9409999847412109},{"id":"https://openalex.org/keywords/vascular-tone","display_name":"vascular tone","score":0.6129999756813049},{"id":"https://openalex.org/keywords/blood-pressure-regulation","display_name":"blood pressure regulation","score":0.6980000138282776},{"id":"https://openalex.org/keywords/cardiovascular-homeostasis","display_name":"cardiovascular homeostasis","score":0.734000027179718}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8730478286743164},{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.7105241417884827},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.555428147315979},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.5544801354408264},{"id":"https://openalex.org/C2992686903","wikidata":"https://www.wikidata.org/wiki/Q208453","display_name":"Smooth muscle","level":2,"score":0.5374477505683899},{"id":"https://openalex.org/C2781269140","wikidata":"https://www.wikidata.org/wiki/Q24784310","display_name":"Melatonin receptor","level":3,"score":0.4688701927661896},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.46153414249420166},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4260874390602112},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4089365601539612},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.35904520750045776}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:5193830","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/10.1161/circ.124.suppl_21.A16932","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7246000170707703}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5199999809265137}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2226350994","https://openalex.org/W796708859","https://openalex.org/W2000086793","https://openalex.org/W2898204268","https://openalex.org/W2903759039","https://openalex.org/W2127986469","https://openalex.org/W2799469801","https://openalex.org/W2014017476","https://openalex.org/W7029915841","https://openalex.org/W3015613341"],"abstract_inverted_index":{"Introduction:":[0],"Increasing":[1],"evidence":[2],"indicates":[3],"that":[4],"melatonin":[5],"plays":[6],"a":[7],"role":[8],"in":[9],"cardiovascular":[10],"homeostasis":[11],"by":[12],"regulating":[13],"blood":[14,20,24],"vessel":[15],"diameter,":[16],"thereby":[17],"impacting":[18],"arterial":[19],"pressure":[21],"and":[22],"local":[23],"...":[25]},"counts_by_year":[{"year":2014,"cited_by_count":2}],"updated_date":"2026-08-08T07:41:36.138363","created_date":"2016-06-24T00:00:00"}