{"id":"https://openalex.org/W51633192","doi":null,"title":"Iconography : Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies","display_name":"Iconography : Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies","publication_year":2012,"publication_date":"2012-12-09","ids":{"openalex":"https://openalex.org/W51633192","mag":"51633192"},"language":"en","primary_location":{"id":"mag:51633192","doi":null,"is_oa":false,"landing_page_url":"http://www.em-consulte.com/en/article/751580/iconosup","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054806342","display_name":"Jody T. Mack","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jody T. Mack","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003491112","display_name":"Carol B. Brown","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carol B. Brown","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050285439","display_name":"Tracy E. Garrett","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tracy E. Garrett","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072741568","display_name":"Joachim D. K. Uys","orcid":"https://orcid.org/0000-0002-4213-9356","observed_orcids":["https://orcid.org/0000-0002-4213-9356"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joachim D. Uys","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4213-9356","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000545163","display_name":"Danyelle M. Townsend","orcid":"https://orcid.org/0000-0003-4679-1891","observed_orcids":["https://orcid.org/0000-0003-4679-1891"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Danyelle M. Townsend","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4679-1891","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5068656271","display_name":"Kenneth D. Tew","orcid":"https://orcid.org/0000-0002-2117-7521","observed_orcids":["https://orcid.org/0000-0002-2117-7521"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kenneth D. Tew","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2117-7521","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0057556,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.007400000002235174,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abca2","display_name":"ABCA2","score":0.8579999804496765},{"id":"https://openalex.org/keywords/abc-transporters","display_name":"ABC transporters","score":0.9079999923706055},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.6549999713897705},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.7990000247955322},{"id":"https://openalex.org/keywords/multidrug-resistance","display_name":"multidrug resistance","score":0.5149999856948853},{"id":"https://openalex.org/keywords/estrogen-receptor","display_name":"estrogen receptor","score":0.39100000262260437}],"concepts":[{"id":"https://openalex.org/C44312359","wikidata":"https://www.wikidata.org/wiki/Q286958","display_name":"ATP-binding cassette transporter","level":4,"score":0.7129497528076172},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.6301382780075073},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.47550708055496216},{"id":"https://openalex.org/C501303744","wikidata":"https://www.wikidata.org/wiki/Q208145","display_name":"Iconography","level":2,"score":0.41395413875579834},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3902207612991333},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3133196234703064},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30967289209365845},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1822318434715271},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.1568376123905182},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:51633192","doi":null,"is_oa":false,"landing_page_url":"http://www.em-consulte.com/en/article/751580/iconosup","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1993591081","https://openalex.org/W2112047199","https://openalex.org/W2749273521","https://openalex.org/W7144520357","https://openalex.org/W2282463185","https://openalex.org/W1998333674","https://openalex.org/W2095741369","https://openalex.org/W2527721894","https://openalex.org/W6922821933","https://openalex.org/W2897184745"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2016-06-24T00:00:00"}