{"id":"https://openalex.org/W5095783","doi":null,"title":"Multiple primary cancers and HPV infection: are they related?","display_name":"Multiple primary cancers and HPV infection: are they related?","publication_year":1999,"publication_date":"1999-03-01","ids":{"openalex":"https://openalex.org/W5095783","mag":"5095783","pmid":"https://pubmed.ncbi.nlm.nih.gov/10374677"},"language":"en","primary_location":{"id":"pmid:10374677","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10374677","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of experimental & clinical cancer research : CR","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006026544","display_name":"Elin M. Hennig","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"E M Hennig","raw_affiliation_strings":["Department of Pathology and Institute for Cancer Research, The Norwegian Radium Hospital, University of Oslo, Montebello"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Institute for Cancer Research, The Norwegian Radium Hospital, University of Oslo, Montebello","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112801154","display_name":"John M. Nesland","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J M Nesland","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064085531","display_name":"Anna Di Lonardo","orcid":"https://orcid.org/0000-0003-1462-7659","observed_orcids":["https://orcid.org/0000-0003-1462-7659"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Di Lonardo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5084435760","display_name":"Aldo Venuti","orcid":"https://orcid.org/0000-0003-2322-6857","observed_orcids":["https://orcid.org/0000-0003-2322-6857"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Venuti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6902,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.6713446,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"18","issue":"1","first_page":"53","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14078","display_name":"Multiple and Secondary Primary Cancers","score":0.5565999746322632,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T14078","display_name":"Multiple and Secondary Primary Cancers","score":0.5565999746322632,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.4242999851703644,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.010499999858438969,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-primary-neoplasms","display_name":"multiple primary neoplasms","score":0.9300000071525574},{"id":"https://openalex.org/keywords/hpv-16","display_name":"HPV16","score":0.9309999942779541},{"id":"https://openalex.org/keywords/hodgkin-lymphoma","display_name":"Hodgkin's disease","score":0.9129999876022339},{"id":"https://openalex.org/keywords/cervical-carcinoma-in-situ","display_name":"cervical carcinoma in situ","score":0.828000009059906},{"id":"https://openalex.org/keywords/breast-adenocarcinoma","display_name":"breast adenocarcinoma","score":0.949999988079071},{"id":"https://openalex.org/keywords/second-primary-tumours","display_name":"second primary tumours","score":0.8709999918937683},{"id":"https://openalex.org/keywords/exogenous-risk-factors","display_name":"exogenous risk factors","score":0.6499999761581421},{"id":"https://openalex.org/keywords/viral-etiology-of-cancer","display_name":"viral etiology of cancer","score":0.5929999947547913}],"concepts":[{"id":"https://openalex.org/C2777740455","wikidata":"https://www.wikidata.org/wiki/Q666412","display_name":"Cervix","level":3,"score":0.6246106624603271},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.5768359899520874},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.47477149963378906},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4720234274864197},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4602133333683014},{"id":"https://openalex.org/C2994532551","wikidata":"https://www.wikidata.org/wiki/Q184627","display_name":"Human papillomavirus","level":2,"score":0.41615837812423706},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.40704819560050964},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39313244819641113},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37413841485977173},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.36996281147003174},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.33060014247894287}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D002278","descriptor_name":"Carcinoma in Situ","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006689","descriptor_name":"Hodgkin Disease","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009378","descriptor_name":"Neoplasms, Multiple Primary","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D014412","descriptor_name":"Tumor Virus Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:10374677","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10374677","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of experimental & clinical cancer research : CR","raw_type":"Case Reports"},{"id":"mag:5095783","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10374677","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":5,"referenced_works":["https://openalex.org/W1979675537","https://openalex.org/W1981616671","https://openalex.org/W2036918065","https://openalex.org/W2333455927","https://openalex.org/W4245765693"],"related_works":["https://openalex.org/W2006488690","https://openalex.org/W2072499828","https://openalex.org/W2115882661","https://openalex.org/W93105641","https://openalex.org/W1956336792","https://openalex.org/W2468673155","https://openalex.org/W2052072751","https://openalex.org/W7129219104","https://openalex.org/W2410756357","https://openalex.org/W2070372307"],"abstract_inverted_index":{"Multiple":[0],"primary":[1,92],"cancers":[2],"have":[3],"been":[4,33],"reported":[5],"with":[6,42],"increasing":[7],"frequency":[8],"in":[9,22,25,90],"recent":[10],"years,":[11],"but":[12],"the":[13,26,54,62,67],"presence":[14,68],"of":[15,19,39,53,69,73,94],"foreign":[16],"DNA":[17,70],"sequences":[18,72],"infectious":[20],"agents":[21],"tumours":[23,93],"arising":[24],"same":[27],"patient":[28,41],"has":[29],"so":[30],"far":[31],"not":[32],"investigated.":[34],"We":[35],"report":[36],"a":[37,40],"case":[38],"Hodgkin's":[43],"lymphoma,":[44],"an":[45,51,85],"\"in":[46],"situ\"":[47],"cervix":[48],"carcinoma":[49],"and":[50,56],"adenocarcinoma":[52],"right":[55],"left":[57],"mammary":[58],"gland.":[59],"In":[60],"all":[61],"tumour":[63],"samples":[64],"we":[65],"detected":[66],"genomic":[71],"Papillomavirus":[74],"type":[75],"16.":[76],"Our":[77],"results":[78],"suggest":[79],"that":[80],"HPV":[81],"infection":[82],"may":[83],"be":[84],"exogenous":[86],"risk":[87],"factor":[88],"even":[89],"second":[91],"non-epithelial":[95],"origin.":[96]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}