{"id":"https://openalex.org/W50808647","doi":"https://doi.org/10.1182/blood.v92.10.3546","title":"Bone Marrow Transplantation for Children Less Than 2 Years of Age With Acute Myelogenous Leukemia or Myelodysplastic Syndrome","display_name":"Bone Marrow Transplantation for Children Less Than 2 Years of Age With Acute Myelogenous Leukemia or Myelodysplastic Syndrome","publication_year":1998,"publication_date":"1998-11-15","ids":{"openalex":"https://openalex.org/W50808647","doi":"https://doi.org/10.1182/blood.v92.10.3546","mag":"50808647","pmid":"https://pubmed.ncbi.nlm.nih.gov/9808546"},"language":"en","primary_location":{"id":"doi:10.1182/blood.v92.10.3546","doi":"https://doi.org/10.1182/blood.v92.10.3546","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v92.10.3546","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045176208","display_name":"Ann E. Woolfrey","orcid":"https://orcid.org/0000-0001-7222-3607","observed_orcids":["https://orcid.org/0000-0001-7222-3607"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ann E. Woolfrey","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023949296","display_name":"Ted Alan Gooley","orcid":"https://orcid.org/0000-0002-8182-3652","observed_orcids":["https://orcid.org/0000-0002-8182-3652"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ted A. Gooley","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031662456","display_name":"Eric L. Sievers","orcid":"https://orcid.org/0000-0002-0794-9441","observed_orcids":["https://orcid.org/0000-0002-0794-9441"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric L. Sievers","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075729666","display_name":"Laurie A. Milner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurie A. Milner","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108214574","display_name":"Robert G. Andrews","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert G. Andrews","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040299600","display_name":"Mark C. Walters","orcid":"https://orcid.org/0000-0002-6515-4559","observed_orcids":["https://orcid.org/0000-0002-6515-4559"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Walters","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081853916","display_name":"Paul A. Hoffmeister","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul Hoffmeister","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030733029","display_name":"John A. Hansen","orcid":"https://orcid.org/0000-0001-5984-9701","observed_orcids":["https://orcid.org/0000-0001-5984-9701"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John A. Hansen","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060783496","display_name":"Claudio Anasetti","orcid":"https://orcid.org/0000-0002-0119-0622","observed_orcids":["https://orcid.org/0000-0002-0119-0622"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Claudio Anasetti","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111564617","display_name":"Eileen M. Bryant","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eileen Bryant","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056405520","display_name":"Frederick R. Appelbaum","orcid":"https://orcid.org/0000-0002-1839-5069","observed_orcids":["https://orcid.org/0000-0002-1839-5069"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frederick R. Appelbaum","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103391116","display_name":"Jean E. Sanders","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jean E. Sanders","raw_affiliation_strings":["From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Fred Hutchinson Cancer Research Center and University of Washington Departments of Pediatrics and Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":2.6748,"has_fulltext":false,"cited_by_count":53,"citation_normalized_percentile":{"value":0.8898264,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"92","issue":"10","first_page":"3546","last_page":"3556"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12900","display_name":"Organ and Tissue Transplantation Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-marrow-transplantation","display_name":"bone marrow transplantation","score":0.9440000057220459},{"id":"https://openalex.org/keywords/infants","display_name":"infants","score":0.6000000238418579},{"id":"https://openalex.org/keywords/acute-myeloid-leukemia","display_name":"acute myeloid leukemia","score":0.972000002861023},{"id":"https://openalex.org/keywords/myelodysplastic-syndrome","display_name":"myelodysplastic syndrome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.7139999866485596},{"id":"https://openalex.org/keywords/graft-versus-host-disease","display_name":"graft-versus-host disease","score":0.8790000081062317},{"id":"https://openalex.org/keywords/cyclophosphamide-conditioning","display_name":"cyclophosphamide conditioning","score":0.7720000147819519},{"id":"https://openalex.org/keywords/total-body-irradiation","display_name":"total body irradiation","score":0.9300000071525574},{"id":"https://openalex.org/keywords/busulfan","display_name":"busulfan","score":0.9399999976158142},{"id":"https://openalex.org/keywords/methotrexate-prophylaxis","display_name":"methotrexate prophylaxis","score":0.8059999942779541},{"id":"https://openalex.org/keywords/cyclosporine","display_name":"cyclosporine","score":0.9430000185966492},{"id":"https://openalex.org/keywords/haploidentical-donor","display_name":"haploidentical donor","score":0.7459999918937683},{"id":"https://openalex.org/keywords/unrelated-donor","display_name":"unrelated donor","score":0.5099999904632568},{"id":"https://openalex.org/keywords/second-transplant","display_name":"second transplant","score":0.48100000619888306},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.6389999985694885}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8194078207015991},{"id":"https://openalex.org/C2780611847","wikidata":"https://www.wikidata.org/wiki/Q348922","display_name":"Busulfan","level":4,"score":0.7825117111206055},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6176745891571045},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.5924879312515259},{"id":"https://openalex.org/C2778880498","wikidata":"https://www.wikidata.org/wiki/Q1986672","display_name":"Total body irradiation","level":4,"score":0.54804927110672},{"id":"https://openalex.org/C88879693","wikidata":"https://www.wikidata.org/wiki/Q217690","display_name":"Cumulative incidence","level":3,"score":0.5325184464454651},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5101957321166992},{"id":"https://openalex.org/C2780817109","wikidata":"https://www.wikidata.org/wiki/Q954625","display_name":"Myelodysplastic syndromes","level":3,"score":0.4976058304309845},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4899698793888092},{"id":"https://openalex.org/C2778720950","wikidata":"https://www.wikidata.org/wiki/Q424972","display_name":"Prednisone","level":2,"score":0.47630083560943604},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.47367674112319946},{"id":"https://openalex.org/C2781059491","wikidata":"https://www.wikidata.org/wiki/Q422232","display_name":"Methotrexate","level":2,"score":0.47180691361427307},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.46939247846603394},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4476553201675415},{"id":"https://openalex.org/C2779972918","wikidata":"https://www.wikidata.org/wiki/Q1194520","display_name":"Graft-versus-host disease","level":3,"score":0.4225544333457947},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.33926665782928467}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002423","descriptor_name":"Cause of Death","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006086","descriptor_name":"Graft vs Host Disease","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006086","descriptor_name":"Graft vs Host Disease","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D006086","descriptor_name":"Graft vs Host Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D006130","descriptor_name":"Growth Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007951","descriptor_name":"Leukemia, Myeloid","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D007951","descriptor_name":"Leukemia, Myeloid","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009190","descriptor_name":"Myelodysplastic Syndromes","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009190","descriptor_name":"Myelodysplastic Syndromes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012074","descriptor_name":"Remission Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014184","descriptor_name":"Transplantation, Homologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016026","descriptor_name":"Bone Marrow Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D016026","descriptor_name":"Bone Marrow Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016026","descriptor_name":"Bone Marrow Transplantation","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D016879","descriptor_name":"Salvage Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017211","descriptor_name":"Treatment Failure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017567","descriptor_name":"Karnofsky Performance Status","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019172","descriptor_name":"Transplantation Conditioning","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1182/blood.v92.10.3546","doi":"https://doi.org/10.1182/blood.v92.10.3546","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v92.10.3546","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"doi:10.1182/blood.v92.10.3546.422k37_3546_3556","doi":"https://doi.org/10.1182/blood.v92.10.3546.422k37_3546_3556","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v92.10.3546.422k37_3546_3556","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"pmid:9808546","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9808546","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G30144808","display_name":null,"funder_award_id":"CA18029","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3034927040","display_name":"AUTOLOGOUS MORROW TRANSPLANTATION","funder_award_id":"P01CA047748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3949574488","display_name":null,"funder_award_id":"DK 02431","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G486636648","display_name":"DEVELOPMENTAL REGULATION OF HLA DQ GENES","funder_award_id":"K08DK002431","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G5715338687","display_name":null,"funder_award_id":"CA-47748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000906164","display_name":"Adult Leukemia Research Center","funder_award_id":"P01CA018029","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":63,"referenced_works":["https://openalex.org/W4474461","https://openalex.org/W5387557","https://openalex.org/W100647374","https://openalex.org/W138215329","https://openalex.org/W149850588","https://openalex.org/W178828275","https://openalex.org/W285482863","https://openalex.org/W1274344746","https://openalex.org/W1532190041","https://openalex.org/W1562876511","https://openalex.org/W1564109452","https://openalex.org/W1573785776","https://openalex.org/W1579352764","https://openalex.org/W1707184873","https://openalex.org/W1772206618","https://openalex.org/W1879738845","https://openalex.org/W1934171667","https://openalex.org/W1937764639","https://openalex.org/W1954992673","https://openalex.org/W1979300931","https://openalex.org/W1993561248","https://openalex.org/W1995609278","https://openalex.org/W2008201186","https://openalex.org/W2017569714","https://openalex.org/W2028295142","https://openalex.org/W2034740985","https://openalex.org/W2054582792","https://openalex.org/W2056097741","https://openalex.org/W2058507451","https://openalex.org/W2084886561","https://openalex.org/W2096321034","https://openalex.org/W2106881064","https://openalex.org/W2115402396","https://openalex.org/W2129843915","https://openalex.org/W2139195420","https://openalex.org/W2150113701","https://openalex.org/W2157633619","https://openalex.org/W2240289126","https://openalex.org/W2255045134","https://openalex.org/W2257559310","https://openalex.org/W2272218722","https://openalex.org/W2276362528","https://openalex.org/W2303583010","https://openalex.org/W2322358118","https://openalex.org/W2335701371","https://openalex.org/W2341266869","https://openalex.org/W2343385965","https://openalex.org/W2396590217","https://openalex.org/W2404754711","https://openalex.org/W2407208193","https://openalex.org/W2408431432","https://openalex.org/W2408612068","https://openalex.org/W2416756744","https://openalex.org/W2416876555","https://openalex.org/W2427820435","https://openalex.org/W2443378833","https://openalex.org/W2466106285","https://openalex.org/W2467788979","https://openalex.org/W3022425467","https://openalex.org/W3041047318","https://openalex.org/W4232845608","https://openalex.org/W4285719527","https://openalex.org/W4299659288"],"related_works":["https://openalex.org/W2054433465","https://openalex.org/W1907798206","https://openalex.org/W2060336095","https://openalex.org/W2464167268","https://openalex.org/W2401486723","https://openalex.org/W2395081506","https://openalex.org/W2325621095","https://openalex.org/W2061873065","https://openalex.org/W7063682349","https://openalex.org/W2418956611"],"abstract_inverted_index":{"We":[0],"analyzed":[1],"results":[2],"of":[3,10,26,93,135,155,187,195,229,233,248,261,288,303,310,326,378],"40":[4],"infants":[5,345,379],"less":[6],"than":[7,239,254],"2":[8],"years":[9,256],"age":[11],"who":[12],"received":[13,223],"bone":[14],"marrow":[15,225],"transplants":[16,226],"(BMT)":[17],"between":[18],"May":[19],"1974":[20],"and":[21,44,65,109,143,158,179,183,200,215,219,231,246,263,268,276,278,307,318,331,357],"January":[22],"1995":[23],"for":[24,120,126,132,169,189,203,227,237,270,280,334,339,375],"treatment":[25,228],"acute":[27],"myelogenous":[28],"leukemia":[29],"(AML;":[30],"N":[31,38,84],"=":[32,39,85,90],"34)":[33],"or":[34,62,87,128,212,284],"myelodysplastic":[35],"syndrome":[36],"(MDS;":[37],"6)":[40],"to":[41,329],"determine":[42],"outcome":[43,350],"survival":[45,262,265],"performance.":[46],"Among":[47],"the":[48,165,185,289,376],"AML":[49,181,221,250,347],"patients,":[50,157],"13":[51],"were":[52,57,67,72],"in":[53,58,68,76,153,162,171,175,206,273,363],"first":[54,60,207,210,274,282,364],"remission,":[55,64,208,214],"9":[56],"untreated":[59,209,281],"relapse":[61,196,211,283,294],"second":[63,213,224,285],"12":[66],"refractory":[69,293],"relapse.":[70,216],"Patients":[71],"conditioned":[73],"with":[74,78,292,301,346,354,380],"cyclophosphamide":[75],"combination":[77],"either":[79],"total":[80],"body":[81],"irradiation":[82],"(TBI;":[83],"29)":[86],"busulfan":[88],"(N":[89],"11).":[91],"Source":[92],"stem":[94],"cells":[95],"included":[96,315],"6":[97,243],"autologous":[98],"donors,":[99],"15":[100],"HLA":[101],"genotypically":[102],"identical":[103],"siblings,":[104],"14":[105],"haploidentical":[106],"family":[107],"members,":[108],"5":[110,232],"unrelated":[111],"donors.":[112],"Graft-versus-host":[113],"disease":[114,304],"(GVHD)":[115],"prophylaxis":[116],"was":[117,141,146,184,298,323,337],"methotrexate":[118],"(MTX)":[119],"17,":[121],"MTX":[122],"plus":[123,130],"cyclosporine":[124],"(CSP)":[125],"14,":[127],"CSP":[129],"prednisone":[131],"3.":[133],"Incidence":[134],"severe":[136],"(grade":[137],"3-4)":[138],"regimen-related":[139],"toxicity":[140],"10%":[142],"transplant-related":[144],"mortality":[145],"10%.":[147],"Acute":[148],"GVHD":[149,160],"(grades":[150],"II-III)":[151],"occurred":[152,174],"39%":[154],"allogeneic":[156,370],"chronic":[159],"developed":[161],"40%.":[163],"Relapse,":[164],"most":[166],"significant":[167],"problem":[168],"patients":[170,182,204,222,245,251,271,290],"this":[172],"study,":[173],"1":[176],"MDS":[177,218,244],"patient":[178],"23":[180],"cause":[186],"death":[188],"19":[190],"patients.":[191],"The":[192,258],"2-year":[193],"probabilities":[194,260],"are":[197,266],"46%,":[198],"67%,":[199],"92%,":[201],"respectively,":[202],"transplanted":[205,272,291],"One":[217],"8":[220],"relapse,":[230],"these":[234],"survive":[235,252,295],"disease-free":[236,264],"more":[238,253],"1.5":[240,255],"years.":[241],"All":[242],"11":[247],"34":[249],"later.":[257],"5-year":[259],"54%":[267],"38%":[269],"remission":[275,365],"33%":[277],"22%":[279],"remission.":[286],"None":[287],"disease-free.":[296],"Outcome":[297],"significantly":[299],"associated":[300],"phase":[302],"at":[305],"transplantation":[306],"pretransplant":[308],"diagnosis":[309],"extramedullary":[311],"disease.":[312],"Long-term":[313],"sequelae":[314],"growth":[316],"failure":[317],"hormonal":[319],"deficiencies.":[320],"Survival":[321],"performance":[322],"a":[324],"median":[325],"100%":[327],"(80%":[328],"100%)":[330],"neurologic":[332],"development":[333],"all":[335],"survivors":[336],"appropriate":[338],"age.":[340],"This":[341],"study":[342],"indicates":[343],"that":[344,358],"have":[348],"similar":[349],"after":[351],"BMT":[352,359,371],"compared":[353],"older":[355],"children":[356],"should":[360],"be":[361],"performed":[362],"whenever":[366],"possible.":[367],"In":[368],"addition,":[369],"provides":[372],"effective":[373],"therapy":[374],"majority":[377],"MDS.":[381]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}