{"id":"https://openalex.org/W49371899","doi":null,"title":"Molecular detection of B-cell neoplasms by specific DNA methylation biomarkers.","display_name":"Molecular detection of B-cell neoplasms by specific DNA methylation biomarkers.","publication_year":2010,"publication_date":"2010-01-28","ids":{"openalex":"https://openalex.org/W49371899","mag":"49371899","pmid":"https://pubmed.ncbi.nlm.nih.gov/20224725","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2836504"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2836504","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2836504","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Clin Exp Pathol","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2836504","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001516916","display_name":"Michael Wang","orcid":"https://orcid.org/0000-0001-7009-6958","observed_orcids":["https://orcid.org/0000-0001-7009-6958"]},"institutions":[{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael X Wang","raw_affiliation_strings":["Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO, USA. wangmx@health.missouri.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO, USA. wangmx@health.missouri.edu","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111422129","display_name":"Huan-You Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Huan-You Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101785912","display_name":"Xiaohui Zhao","orcid":"https://orcid.org/0000-0002-6921-2787","observed_orcids":["https://orcid.org/0000-0002-6921-2787"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaohui Zhao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013760854","display_name":"Srilatha Nalluri","orcid":"https://orcid.org/0000-0002-7265-8165","observed_orcids":["https://orcid.org/0000-0002-7265-8165"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nalluri Srilatha","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004769278","display_name":"Dali Zheng","orcid":"https://orcid.org/0000-0003-2345-4040","observed_orcids":["https://orcid.org/0000-0003-2345-4040"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dali Zheng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061372791","display_name":"Huidong Shi","orcid":"https://orcid.org/0000-0003-1137-3390","observed_orcids":["https://orcid.org/0000-0003-1137-3390"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Huidong Shi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Jie Ning","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jie Ning","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015112123","display_name":"Deiter James Duff","orcid":"https://orcid.org/0000-0002-7595-6141","observed_orcids":["https://orcid.org/0000-0002-7595-6141"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Deiter J Duff","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073848797","display_name":"Kristen H. Taylor","orcid":"https://orcid.org/0000-0001-9336-9824","observed_orcids":["https://orcid.org/0000-0001-9336-9824"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kristen H Taylor","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057689555","display_name":"Barbara A. Gruner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barbara A Gruner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5035776237","display_name":"Charles W. Caldwell","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charles W Caldwell","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9807,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.76576221,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"3","issue":"3","first_page":"265","last_page":"79"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.9564999938011169,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.9564999938011169,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.03660000115633011,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/b-cell-malignancies","display_name":"B-cell malignancies","score":0.9399999976158142},{"id":"https://openalex.org/keywords/dna-methylation-markers","display_name":"DNA methylation biomarkers","score":0.9010000228881836},{"id":"https://openalex.org/keywords/b-cell-acute-lymphoblastic-leukemia","display_name":"B-cell acute lymphoblastic leukemia","score":0.8159999847412109},{"id":"https://openalex.org/keywords/dlc1","display_name":"DLC1","score":0.8539999723434448},{"id":"https://openalex.org/keywords/cpg-island-methylation","display_name":"CpG island methylation","score":0.9580000042915344},{"id":"https://openalex.org/keywords/pcr-detection","display_name":"PCR detection","score":0.7409999966621399},{"id":"https://openalex.org/keywords/bone-marrow","display_name":"bone marrow","score":0.7149999737739563},{"id":"https://openalex.org/keywords/peripheral-blood","display_name":"peripheral blood","score":0.8849999904632568},{"id":"https://openalex.org/keywords/clinical-outcome-correlation","display_name":"clinical outcome correlation","score":0.4480000138282776}],"concepts":[{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.7389106750488281},{"id":"https://openalex.org/C196166836","wikidata":"https://www.wikidata.org/wiki/Q902926","display_name":"Immunophenotyping","level":3,"score":0.7117066979408264},{"id":"https://openalex.org/C140173407","wikidata":"https://www.wikidata.org/wiki/Q1138358","display_name":"CpG site","level":5,"score":0.6650038361549377},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.6296916007995605},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.6089960932731628},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5158921480178833},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4258022606372833},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.41586992144584656},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.4103385806083679},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.3819631338119507},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.36068496108055115},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3532848358154297},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2590990960597992},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.23529300093650818},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.20275378227233887},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19275814294815063},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.15833157300949097}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004273","descriptor_name":"DNA, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015448","descriptor_name":"Leukemia, B-Cell","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D015448","descriptor_name":"Leukemia, B-Cell","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015448","descriptor_name":"Leukemia, B-Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020690","descriptor_name":"GTPase-Activating Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025521","descriptor_name":"Tumor Suppressor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D025521","descriptor_name":"Tumor Suppressor Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047908","descriptor_name":"Intracellular Signaling Peptides and Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2836504","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2836504","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Clin Exp Pathol","raw_type":"Text"},{"id":"pmid:20224725","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20224725","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of clinical and experimental pathology","raw_type":"Evaluation Study"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt06s715vh","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/06s715vh","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Clinical and Experimental Pathology, vol 3, iss 3","raw_type":"article"},{"id":"mag:2188348079","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/06s715vh.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2836504","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2836504","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Clin Exp Pathol","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6332127958","display_name":"Integrated Genetic and Epigenetic Biomarkers for Molecular Epidemiology","funder_award_id":"R03CA123565","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7320102530","display_name":"Epigenetic Targeting in Non-Hodgkin's Lymphoma","funder_award_id":"R21CA123018","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W92289489","https://openalex.org/W183213617","https://openalex.org/W1529084294","https://openalex.org/W1582369285","https://openalex.org/W1605230984","https://openalex.org/W1755052449","https://openalex.org/W1965262464","https://openalex.org/W1965634393","https://openalex.org/W1968263601","https://openalex.org/W1994465394","https://openalex.org/W1996342200","https://openalex.org/W2013790801","https://openalex.org/W2043147472","https://openalex.org/W2046509449","https://openalex.org/W2048410884","https://openalex.org/W2054098724","https://openalex.org/W2059357064","https://openalex.org/W2065869497","https://openalex.org/W2071832186","https://openalex.org/W2075139424","https://openalex.org/W2076234267","https://openalex.org/W2080636110","https://openalex.org/W2087079130","https://openalex.org/W2088262832","https://openalex.org/W2098582295","https://openalex.org/W2100025372","https://openalex.org/W2102844816","https://openalex.org/W2104311978","https://openalex.org/W2106680700","https://openalex.org/W2128112098","https://openalex.org/W2143995836","https://openalex.org/W2145669281","https://openalex.org/W2147049379","https://openalex.org/W2156381424","https://openalex.org/W2157843820","https://openalex.org/W2166355785","https://openalex.org/W2167213955","https://openalex.org/W2169047291","https://openalex.org/W2171676482","https://openalex.org/W2583420140"],"related_works":["https://openalex.org/W2188348079","https://openalex.org/W2583420140","https://openalex.org/W4408273228","https://openalex.org/W2150293957","https://openalex.org/W1992703511","https://openalex.org/W2949231511","https://openalex.org/W2016025537","https://openalex.org/W2098582295","https://openalex.org/W2320625381","https://openalex.org/W1966324832"],"abstract_inverted_index":{"A":[0],"novel,":[1],"easy":[2],"to":[3,12,91,122],"perform":[4],"PCR-based":[5],"method":[6,33,109],"employing":[7],"specific":[8],"DNA":[9],"methylation":[10,98],"biomarkers":[11],"detect":[13],"B-cell":[14,20,118],"neoplasms":[15],"in":[16,45,76,114,120],"a":[17,52],"variety":[18],"of":[19,71,117],"lines":[21],"and":[22,67,95,131],"B":[23],"lymphoblastic":[24],"leukemia":[25],"(B-ALL)":[26],"patient":[27,102],"specimens":[28],"has":[29],"been":[30],"developed.":[31],"This":[32],"detects":[34],"as":[35,37,126],"few":[36],"5":[38],"B-ALL":[39,43,72,88],"cells,":[40],"or":[41],"1":[42],"cell":[44],"1,000,000":[46],"normal":[47],"background":[48],"blood":[49,82],"cells":[50],"using":[51],"single":[53],"marker,":[54],"DLC-1":[55,97],"gene":[56],"CpG":[57],"island":[58],"(CGI)":[59],"methylation.":[60],"By":[61],"adding":[62],"two":[63],"additional":[64],"markers":[65],"PCDHGA12":[66],"RPIB9,":[68],"over":[69],"80%":[70],"cases":[73,89],"were":[74],"detected":[75],"patients'":[77],"bone":[78],"marrow":[79],"and/or":[80],"peripheral":[81],"specimens.":[83],"We":[84],"have":[85],"traced":[86],"clinical":[87,103,127],"up":[90],"10":[92],"years":[93],"retrospectively":[94],"the":[96,115],"is":[99],"correlated":[100],"with":[101],"status.":[104],"Thus,":[105],"this":[106],"epigenetic-based":[107],"molecular":[108],"demonstrates":[110],"its":[111],"potential":[112],"use":[113],"diagnosis":[116],"neoplasia,":[119],"addition":[121],"traditional":[123],"approach":[124],"such":[125],"features,":[128],"morphology,":[129],"immunophenotype,":[130],"genetic":[132],"analysis.":[133]},"counts_by_year":[{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}