{"id":"https://openalex.org/W48692949","doi":"https://doi.org/10.1520/jfs11240j","title":"Ingestion of Isobutyl Nitrite, A Recreational Chemical of Abuse, Causing Fatal Methemoglobinemia","display_name":"Ingestion of Isobutyl Nitrite, A Recreational Chemical of Abuse, Causing Fatal Methemoglobinemia","publication_year":1987,"publication_date":"1987-11-01","ids":{"openalex":"https://openalex.org/W48692949","doi":"https://doi.org/10.1520/jfs11240j","mag":"48692949","pmid":"https://pubmed.ncbi.nlm.nih.gov/3430141"},"language":"en","primary_location":{"id":"doi:10.1520/jfs11240j","doi":"https://doi.org/10.1520/jfs11240j","is_oa":false,"landing_page_url":"https://doi.org/10.1520/jfs11240j","pdf_url":null,"source":{"id":"https://openalex.org/S62072220","display_name":"Journal of Forensic Sciences","issn_l":"0022-1198","issn":["0022-1198","1556-4029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Forensic Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"JB O'Toole","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4391768165","display_name":"Commonwealth of Massachusetts","ror":"https://ror.org/05h4vvj02","country_code":"US","type":"government","lineage":["https://openalex.org/I4391768165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JB O'Toole","raw_affiliation_strings":["Commonwealth of Massachusetts, Office of the Medical Examiner 1 Medical examiner of Bristol County, Massachusetts and pathologist for medical examiner of Bristol County , respectively, , Boston, MA "],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Commonwealth of Massachusetts, Office of the Medical Examiner 1 Medical examiner of Bristol County, Massachusetts and pathologist for medical examiner of Bristol County , respectively, , Boston, MA ","institution_ids":["https://openalex.org/I4391768165"]}]},{"author_position":"middle","author":{"id":null,"display_name":"GB Robbins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4391768165","display_name":"Commonwealth of Massachusetts","ror":"https://ror.org/05h4vvj02","country_code":"US","type":"government","lineage":["https://openalex.org/I4391768165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"GB Robbins","raw_affiliation_strings":["Commonwealth of Massachusetts, Office of the Medical Examiner 1 Medical examiner of Bristol County, Massachusetts and pathologist for medical examiner of Bristol County , respectively, , Boston, MA "],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Commonwealth of Massachusetts, Office of the Medical Examiner 1 Medical examiner of Bristol County, Massachusetts and pathologist for medical examiner of Bristol County , respectively, , Boston, MA ","institution_ids":["https://openalex.org/I4391768165"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108373836","display_name":"Douglas S. Dixon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"DS Dixon","raw_affiliation_strings":["Office of the Coroner, County of San Diego 2 deputy medical examiner , , Bldg. 14 5555 Overland Ave. San Diego, CA92123","Deputy medical examiner, Office of the Coroner, County of San Diego, Bldg. 14 5555 Overland Ave. San Diego, CA 92123, US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Office of the Coroner, County of San Diego 2 deputy medical examiner , , Bldg. 14 5555 Overland Ave. San Diego, CA92123","institution_ids":[]},{"raw_affiliation_string":"Deputy medical examiner, Office of the Coroner, County of San Diego, Bldg. 14 5555 Overland Ave. San Diego, CA 92123, US","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4330,"currency":"USD","value_usd":4330},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.00437324,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"32","issue":"6","first_page":"1811","last_page":"1812"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12845","display_name":"Methemoglobinemia and Tumor Lysis Syndrome","score":0.5932999849319458,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12845","display_name":"Methemoglobinemia and Tumor Lysis Syndrome","score":0.5932999849319458,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.36820000410079956,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11635","display_name":"Poisoning and overdose treatments","score":0.02889999933540821,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/isobutyl-nitrite","display_name":"isobutyl nitrite","score":1.0},{"id":"https://openalex.org/keywords/methemoglobinemia","display_name":"methemoglobinemia","score":0.9559999704360962},{"id":"https://openalex.org/keywords/drug-ingestion","display_name":"drug ingestion","score":0.5370000004768372},{"id":"https://openalex.org/keywords/recreational-drug-abuse","display_name":"recreational drug abuse","score":0.8870000243186951},{"id":"https://openalex.org/keywords/sexual-stimulants","display_name":"sexual stimulants","score":0.824999988079071},{"id":"https://openalex.org/keywords/fatal-poisoning","display_name":"fatal poisoning","score":0.5929999947547913},{"id":"https://openalex.org/keywords/forensic-toxicology","display_name":"forensic toxicology","score":0.6110000014305115}],"concepts":[{"id":"https://openalex.org/C2777737778","wikidata":"https://www.wikidata.org/wiki/Q748442","display_name":"Methemoglobinemia","level":2,"score":0.9435864686965942},{"id":"https://openalex.org/C193230392","wikidata":"https://www.wikidata.org/wiki/Q1663054","display_name":"Ingestion","level":2,"score":0.7878250479698181},{"id":"https://openalex.org/C2776963261","wikidata":"https://www.wikidata.org/wiki/Q27888090","display_name":"Amyl nitrite","level":2,"score":0.6747360825538635},{"id":"https://openalex.org/C26865036","wikidata":"https://www.wikidata.org/wiki/Q416833","display_name":"Methemoglobin","level":3,"score":0.5472067594528198},{"id":"https://openalex.org/C2776954882","wikidata":"https://www.wikidata.org/wiki/Q840343","display_name":"Inhalation","level":2,"score":0.5349479913711548},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5158175826072693},{"id":"https://openalex.org/C2780557958","wikidata":"https://www.wikidata.org/wiki/Q211036","display_name":"Stimulant","level":2,"score":0.5061590075492859},{"id":"https://openalex.org/C2776179834","wikidata":"https://www.wikidata.org/wiki/Q72158415","display_name":"Nitrite","level":3,"score":0.48578503727912903},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.44842249155044556},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.37873485684394836},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3614789843559265},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32844698429107666},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3087256848812103},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.27151381969451904},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15102243423461914},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09625574946403503},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.07431402802467346},{"id":"https://openalex.org/C2776384668","wikidata":"https://www.wikidata.org/wiki/Q182168","display_name":"Nitrate","level":2,"score":0.07092520594596863},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008708","descriptor_name":"Methemoglobinemia","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D009573","descriptor_name":"Nitrites","qualifier_ui":"Q000506","qualifier_name":"poisoning","is_major_topic":true},{"descriptor_ui":"D019966","descriptor_name":"Substance-Related Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1520/jfs11240j","doi":"https://doi.org/10.1520/jfs11240j","is_oa":false,"landing_page_url":"https://doi.org/10.1520/jfs11240j","pdf_url":null,"source":{"id":"https://openalex.org/S62072220","display_name":"Journal of Forensic Sciences","issn_l":"0022-1198","issn":["0022-1198","1556-4029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Forensic Sciences","raw_type":"journal-article"},{"id":"pmid:3430141","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3430141","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of forensic sciences","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W1807780199"],"related_works":["https://openalex.org/W1807780199","https://openalex.org/W2005697360","https://openalex.org/W4416385120","https://openalex.org/W2070711298","https://openalex.org/W3132727390","https://openalex.org/W1990822447","https://openalex.org/W1999322043","https://openalex.org/W2414064943","https://openalex.org/W2031054581","https://openalex.org/W2425045847"],"abstract_inverted_index":{"Isobutyl":[0],"nitrite":[1],"is":[2,39,49],"widely":[3],"abused":[4],"as":[5],"a":[6],"sexual":[7],"stimulant":[8],"and":[9],"enhancer":[10],"of":[11,18,45],"discotheque":[12],"dancing.":[13],"Though":[14],"the":[15,37],"usual":[16],"route":[17],"administration":[19],"by":[20],"inhalation":[21],"has":[22],"not":[23],"resulted":[24],"in":[25],"any":[26],"toxicologically":[27],"verified":[28],"deaths,":[29],"there":[30],"may":[31],"be":[32],"fatal":[33],"toxic":[34],"methemoglobinemia":[35],"if":[36],"chemical":[38],"orally":[40],"ingested.":[41],"A":[42],"second":[43],"case":[44],"death":[46],"following":[47],"ingestion":[48],"discussed.":[50]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}