{"id":"https://openalex.org/W48185203","doi":"https://doi.org/10.1016/s0021-9258(17)30239-9","title":"Detergent-solubilized NADPH-cytochrome c(P-450) reductase from the higher plant, Catharanthus roseus. Purification and characterization","display_name":"Detergent-solubilized NADPH-cytochrome c(P-450) reductase from the higher plant, Catharanthus roseus. Purification and characterization","publication_year":1979,"publication_date":"1979-04-01","ids":{"openalex":"https://openalex.org/W48185203","doi":"https://doi.org/10.1016/s0021-9258(17)30239-9","mag":"48185203","pmid":"https://pubmed.ncbi.nlm.nih.gov/107158"},"language":"en","primary_location":{"id":"doi:10.1016/s0021-9258(17)30239-9","doi":"https://doi.org/10.1016/s0021-9258(17)30239-9","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0021-9258(17)30239-9","pdf_url":"https://doi.org/10.1016/s0021-9258(17)30239-9","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/s0021-9258(17)30239-9","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111582674","display_name":"K. Madhava Madyastha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K.M. Madyastha","raw_affiliation_strings":["Department of Biochemistry, St. Louis University School of Medicine, St. Louis, Missouri 63104"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, St. Louis University School of Medicine, St. Louis, Missouri 63104","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110041723","display_name":"Carmine James Coscia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.J. Coscia","raw_affiliation_strings":["Department of Biochemistry, St. Louis University School of Medicine, St. Louis, Missouri 63104"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, St. Louis University School of Medicine, St. Louis, Missouri 63104","institution_ids":["https://openalex.org/I47838141"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I47838141"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":1.3158,"has_fulltext":true,"cited_by_count":76,"citation_normalized_percentile":{"value":0.76241072,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"254","issue":"7","first_page":"2419","last_page":"2427"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.5609999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.5609999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.0778999999165535,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.020600000396370888,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nadph-cytochrome-p450-reductase","display_name":"NADPH-cytochrome P450 reductase","score":0.9850000143051147},{"id":"https://openalex.org/keywords/catharanthus-roseus","display_name":"Catharanthus roseus","score":0.8970000147819519},{"id":"https://openalex.org/keywords/detergent-solubilization","display_name":"detergent solubilization","score":0.9229999780654907},{"id":"https://openalex.org/keywords/enzyme-purification","display_name":"enzyme purification","score":0.8550000190734863},{"id":"https://openalex.org/keywords/enzyme-characterization","display_name":"enzyme characterization","score":0.9599999785423279},{"id":"https://openalex.org/keywords/higher-plants","display_name":"higher plants","score":0.48899999260902405},{"id":"https://openalex.org/keywords/cytochrome-p450","display_name":"cytochrome P450","score":0.8420000076293945}],"concepts":[{"id":"https://openalex.org/C2779906556","wikidata":"https://www.wikidata.org/wiki/Q161093","display_name":"Catharanthus roseus","level":2,"score":0.959019124507904},{"id":"https://openalex.org/C4863142","wikidata":"https://www.wikidata.org/wiki/Q907920","display_name":"Solubilization","level":2,"score":0.7654457688331604},{"id":"https://openalex.org/C134651460","wikidata":"https://www.wikidata.org/wiki/Q3100717","display_name":"Reductase","level":3,"score":0.6145164370536804},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5786927938461304},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.571039080619812},{"id":"https://openalex.org/C2780768313","wikidata":"https://www.wikidata.org/wiki/Q408068","display_name":"Cytochrome","level":3,"score":0.5307647585868835},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3268328905105591},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.32151368260383606},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25836509466171265}],"mesh":[{"descriptor_ui":"D002793","descriptor_name":"Cholic Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003579","descriptor_name":"Cytochrome Reductases","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009251","descriptor_name":"NADPH-Ferrihemoprotein Reductase","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D009251","descriptor_name":"NADPH-Ferrihemoprotein Reductase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010944","descriptor_name":"Plants","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D012995","descriptor_name":"Solubility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013053","descriptor_name":"Spectrophotometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0021-9258(17)30239-9","doi":"https://doi.org/10.1016/s0021-9258(17)30239-9","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0021-9258(17)30239-9","pdf_url":"https://doi.org/10.1016/s0021-9258(17)30239-9","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:107158","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/107158","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0021-9258(17)30239-9","doi":"https://doi.org/10.1016/s0021-9258(17)30239-9","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0021-9258(17)30239-9","pdf_url":"https://doi.org/10.1016/s0021-9258(17)30239-9","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":true},"content_urls":{"grobid_xml":"https://content.openalex.org/works/W48185203.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W87746259","https://openalex.org/W126145571","https://openalex.org/W1038379704","https://openalex.org/W1488511002","https://openalex.org/W1538509373","https://openalex.org/W1569108294","https://openalex.org/W1582769766","https://openalex.org/W1587838414","https://openalex.org/W1775749144","https://openalex.org/W1855109296","https://openalex.org/W1978609573","https://openalex.org/W1982966354","https://openalex.org/W1987545492","https://openalex.org/W2002131874","https://openalex.org/W2008687694","https://openalex.org/W2015656344","https://openalex.org/W2019934106","https://openalex.org/W2028884824","https://openalex.org/W2028924242","https://openalex.org/W2031107830","https://openalex.org/W2046559874","https://openalex.org/W2062254955","https://openalex.org/W2072291087","https://openalex.org/W2078773935","https://openalex.org/W2079106335","https://openalex.org/W2080418255","https://openalex.org/W2082514058","https://openalex.org/W2085804137","https://openalex.org/W2091560133","https://openalex.org/W2092766035","https://openalex.org/W2092906257","https://openalex.org/W2100837269","https://openalex.org/W2110173014","https://openalex.org/W2111301002","https://openalex.org/W2114166458","https://openalex.org/W2135184471","https://openalex.org/W2138990748","https://openalex.org/W2735482738","https://openalex.org/W3118710269","https://openalex.org/W3215323180"],"related_works":["https://openalex.org/W2305629912","https://openalex.org/W1983184576","https://openalex.org/W2002310279","https://openalex.org/W2108922833","https://openalex.org/W2045289045","https://openalex.org/W1582769766","https://openalex.org/W2005749628","https://openalex.org/W1826714264","https://openalex.org/W2134432484","https://openalex.org/W2936668804"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}