{"id":"https://openalex.org/W47891013","doi":null,"title":"Whole body and skeletal muscle protein turnover in recovery from burns.","display_name":"Whole body and skeletal muscle protein turnover in recovery from burns.","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W47891013","mag":"47891013","pmid":"https://pubmed.ncbi.nlm.nih.gov/23386981","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3560488"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:2565548","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3560488","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3560488","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031903364","display_name":"Craig C. Porter","orcid":"https://orcid.org/0000-0003-3657-6645","observed_orcids":["https://orcid.org/0000-0003-3657-6645"]},"institutions":[{"id":"https://openalex.org/I2801713311","display_name":"Shriners Hospitals for Children - Galveston","ror":"https://ror.org/01v95tx09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801713311","https://openalex.org/I4210144267"]},{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Craig Porter","raw_affiliation_strings":["Metabolism Unit, Shriners Hospitals for Children - Galveston Galveston, Texas ; Department of Surgery, University of Texas Medical Branch Galveston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Metabolism Unit, Shriners Hospitals for Children - Galveston Galveston, Texas ; Department of Surgery, University of Texas Medical Branch Galveston, Texas","institution_ids":["https://openalex.org/I2801713311","https://openalex.org/I55302922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008292430","display_name":"Nicholas Michael Hurren","orcid":"https://orcid.org/0000-0003-2993-0079","observed_orcids":["https://orcid.org/0000-0003-2993-0079"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicholas M Hurren","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014429489","display_name":"David Newcomb Herndon","orcid":"https://orcid.org/0000-0002-3861-6463","observed_orcids":["https://orcid.org/0000-0002-3861-6463","https://orcid.org/0000-0003-0396-9442"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David N Herndon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5030048442","display_name":"Elisabet B\u00f8rsheim","orcid":"https://orcid.org/0000-0002-7842-0625","observed_orcids":["https://orcid.org/0000-0002-7842-0625"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elisabet B\u00f8rsheim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":6.1111,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.963447,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"3","issue":"1","first_page":"9","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11399","display_name":"Muscle metabolism and nutrition","score":0.8363999724388123,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11399","display_name":"Muscle metabolism and nutrition","score":0.8363999724388123,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":0.14180000126361847,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.010200000368058681,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/burns","display_name":"burns","score":0.9440000057220459},{"id":"https://openalex.org/keywords/skeletal-muscle-protein-turnover","display_name":"skeletal muscle protein turnover","score":0.9639999866485596},{"id":"https://openalex.org/keywords/whole-body-protein-metabolism","display_name":"whole body protein metabolism","score":0.906000018119812},{"id":"https://openalex.org/keywords/muscle-protein-degradation","display_name":"muscle protein degradation","score":0.7480000257492065},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.6060000061988831},{"id":"https://openalex.org/keywords/stress-response","display_name":"stress response","score":0.5839999914169312},{"id":"https://openalex.org/keywords/caloric-restriction","display_name":"caloric restriction","score":0.5950000286102295},{"id":"https://openalex.org/keywords/burn-recovery","display_name":"burn recovery","score":0.36000001430511475}],"concepts":[{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.8495073318481445},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.7075205445289612},{"id":"https://openalex.org/C2777499176","wikidata":"https://www.wikidata.org/wiki/Q174936","display_name":"Glycogen","level":2,"score":0.6782909631729126},{"id":"https://openalex.org/C96942376","wikidata":"https://www.wikidata.org/wiki/Q21130714","display_name":"Catabolism","level":3,"score":0.6081616878509521},{"id":"https://openalex.org/C2779572773","wikidata":"https://www.wikidata.org/wiki/Q4862551","display_name":"Protein metabolism","level":3,"score":0.5573157072067261},{"id":"https://openalex.org/C197683979","wikidata":"https://www.wikidata.org/wiki/Q14876077","display_name":"Protein catabolism","level":3,"score":0.5234646201133728},{"id":"https://openalex.org/C195580219","wikidata":"https://www.wikidata.org/wiki/Q7251511","display_name":"Protein turnover","level":3,"score":0.5209890007972717},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.519601047039032},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.47474581003189087},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4599543809890747},{"id":"https://openalex.org/C3675279","wikidata":"https://www.wikidata.org/wiki/Q211935","display_name":"Protein biosynthesis","level":2,"score":0.4309612810611725},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38988518714904785},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3513384461402893},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21822664141654968}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:europepmc.org:2565548","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3560488","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3560488","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3560488","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Burns Trauma","raw_type":"Text"},{"id":"pmid:23386981","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23386981","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of burns and trauma","raw_type":"Journal Article"},{"id":"mag:2185212118","doi":null,"is_oa":false,"landing_page_url":"http://ijbt.org/files/ijbt1212004.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:47891013","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23386981","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2565548","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3560488","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000888026","display_name":"UTMB Claude D. Pepper Older Americans Independence Center","funder_award_id":"P30AG024832","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":63,"referenced_works":["https://openalex.org/W1492214939","https://openalex.org/W1507816258","https://openalex.org/W1512838032","https://openalex.org/W1967775253","https://openalex.org/W1974750981","https://openalex.org/W1981177170","https://openalex.org/W1983176108","https://openalex.org/W1983984331","https://openalex.org/W1984380517","https://openalex.org/W1985645871","https://openalex.org/W1985693526","https://openalex.org/W1985895564","https://openalex.org/W1992656598","https://openalex.org/W1993356654","https://openalex.org/W1993983307","https://openalex.org/W1997462178","https://openalex.org/W1999017023","https://openalex.org/W2003680888","https://openalex.org/W2004606127","https://openalex.org/W2005965768","https://openalex.org/W2008757332","https://openalex.org/W2010869486","https://openalex.org/W2012891214","https://openalex.org/W2022482829","https://openalex.org/W2025532982","https://openalex.org/W2026394198","https://openalex.org/W2028618233","https://openalex.org/W2030015146","https://openalex.org/W2031684439","https://openalex.org/W2031929993","https://openalex.org/W2033713750","https://openalex.org/W2036116757","https://openalex.org/W2037831347","https://openalex.org/W2040872874","https://openalex.org/W2047910355","https://openalex.org/W2052230840","https://openalex.org/W2053008838","https://openalex.org/W2056681753","https://openalex.org/W2061825971","https://openalex.org/W2064803824","https://openalex.org/W2069199585","https://openalex.org/W2073070813","https://openalex.org/W2080031014","https://openalex.org/W2081195991","https://openalex.org/W2084688209","https://openalex.org/W2085657776","https://openalex.org/W2089914620","https://openalex.org/W2095299732","https://openalex.org/W2096487945","https://openalex.org/W2114986671","https://openalex.org/W2121320168","https://openalex.org/W2121931449","https://openalex.org/W2122089466","https://openalex.org/W2130574458","https://openalex.org/W2135666344","https://openalex.org/W2150364761","https://openalex.org/W2150766174","https://openalex.org/W2154042628","https://openalex.org/W2156979899","https://openalex.org/W2161337359","https://openalex.org/W2181216182","https://openalex.org/W2327431910","https://openalex.org/W2464726485"],"related_works":["https://openalex.org/W2185212118","https://openalex.org/W2031941799","https://openalex.org/W6893759678","https://openalex.org/W648264047","https://openalex.org/W2047910355","https://openalex.org/W2327431910","https://openalex.org/W1980313571","https://openalex.org/W1987454614","https://openalex.org/W2280656477","https://openalex.org/W2078120455"],"abstract_inverted_index":{"Trauma":[0],"and":[1,90,109,114,120,177,202,270],"critical":[2],"illness":[3],"are":[4,154],"associated":[5],"with":[6],"a":[7,44,76,88,163,170],"stress":[8],"response":[9,183],"that":[10,83,243],"results":[11],"in":[12,29,37,141,161,169,182,233,252,278],"increased":[13],"skeletal":[14,166,188,207,238,244,271,297],"muscle":[15,101,189,199,208,239,245,272,298],"protein":[16,200,240,251,273,299],"catabolism,":[17],"which":[18],"is":[19,49,62,70],"thought":[20],"to":[21,96,105,138,143,158,184,210,236,281],"facilitate":[22,97],"the":[23,30,50,57,73,84,103,151,191,223,262,283,287,294],"synthesis":[24],"of":[25,47,52,59,75,79,93,129,174,193,222,250,264,286,289,296],"acute":[26],"phase":[27],"proteins":[28,35,176],"liver":[31],"as":[32,34],"well":[33],"involved":[36],"immune":[38],"function.":[39],"What":[40],"makes":[41],"burn":[42,257,265],"injury":[43,266,292],"unique":[45],"form":[46],"trauma":[48],"existence":[51],"vast":[53],"skin":[54],"lesions,":[55],"where":[56,118,198],"majority":[58],"afflicted":[60],"tissue":[61],"often":[63],"surgically":[64],"excised":[65],"post":[66],"injury.":[67],"Thereafter,":[68],"recovery":[69],"dependent":[71],"on":[72,150,267,293],"formation":[74],"significant":[77],"quantity":[78],"new":[80],"skin,":[81],"meaning":[82],"burned":[85,225],"patient":[86,226],"requires":[87],"large":[89],"sustained":[91],"supply":[92,230],"amino":[94,195,203,213,231],"acids":[95,111,122,232],"wound":[98],"healing.":[99],"Skeletal":[100],"has":[102],"capacity":[104],"store":[106,249],"surplus":[107],"glucose":[108],"fatty":[110,121],"within":[112,165],"glycogen":[113,119],"triacylglycerol":[115],"depots":[116],"respectively,":[117],"can":[123],"be":[124,139,159,276],"mobilized":[125],"during":[126],"prolonged":[127],"periods":[128],"caloric":[130],"restriction":[131],"or":[132],"heightened":[133],"metabolic":[134],"demand":[135],"(e.g.,":[136],"exercise),":[137],"catabolized":[140],"order":[142],"maintain":[144],"cellular":[145,178],"ATP":[146],"availability.":[147],"Amino":[148],"acids,":[149],"other":[152],"hand,":[153],"not":[155,228],"generally":[156],"considered":[157],"stored":[160],"such":[162],"manner":[164],"muscle,":[167],"i.e.,":[168],"temporary":[171],"pool":[172],"independent":[173],"structural":[175],"organelles":[179],"etc.":[180],"Subsequently,":[181],"severe":[185,256],"thermal":[186],"trauma,":[187],"assumes":[190],"role":[192],"an":[194,247,279],"acid":[196,204,214],"reserve":[197],"breakdown":[201],"release":[205],"from":[206,255],"serves":[209],"buffer":[211],"plasma":[212],"concentrations.":[215],"Interestingly,":[216],"it":[217],"seems":[218],"like":[219],"aggressive":[220],"feeding":[221],"severely":[224],"may":[227],"necessarily":[229],"sufficient":[234],"abundance":[235],"normalize":[237],"metabolism,":[241],"suggesting":[242],"becomes":[246],"essential":[248],"patients":[253],"suffering":[254],"trauma.":[258],"In":[259],"this":[260,290],"article,":[261],"effects":[263],"whole":[268],"body":[269],"metabolism":[274],"will":[275],"discussed":[277],"attempt":[280],"distill":[282],"current":[284],"understanding":[285],"impact":[288],"debilitating":[291],"redistribution":[295],"stores.":[300]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}