{"id":"https://openalex.org/W45728653","doi":null,"title":"Secretory piece and IgA deficiency in a patient with Waldenstrom's macroglobulinemia.","display_name":"Secretory piece and IgA deficiency in a patient with Waldenstrom's macroglobulinemia.","publication_year":1986,"publication_date":"1986-10-01","ids":{"openalex":"https://openalex.org/W45728653","mag":"45728653","pmid":"https://pubmed.ncbi.nlm.nih.gov/3094364"},"language":"en","primary_location":{"id":"pmid:3094364","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3094364","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Case Reports"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064396906","display_name":"Elchanan Nussinson","orcid":"https://orcid.org/0000-0003-4475-8406","observed_orcids":["https://orcid.org/0000-0003-4475-8406"]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]},{"id":"https://openalex.org/I2799294462","display_name":"Emek Medical Center","ror":"https://ror.org/02b988t02","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799294462","https://openalex.org/I64767286"]},{"id":"https://openalex.org/I2800052317","display_name":"Kaplan Medical Center","ror":"https://ror.org/00t0n9020","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2800052317","https://openalex.org/I64767286"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"E Nussinson","raw_affiliation_strings":["Emek Medical Center","Kaplan Medical Center Israel","Tel Aviv University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emek Medical Center","institution_ids":["https://openalex.org/I2799294462"]},{"raw_affiliation_string":"Kaplan Medical Center Israel","institution_ids":["https://openalex.org/I2800052317"]},{"raw_affiliation_string":"Tel Aviv University","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047295157","display_name":"Meir Lahav","orcid":"https://orcid.org/0000-0002-6574-2510","observed_orcids":["https://orcid.org/0000-0002-6574-2510"]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]},{"id":"https://openalex.org/I2799294462","display_name":"Emek Medical Center","ror":"https://ror.org/02b988t02","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799294462","https://openalex.org/I64767286"]},{"id":"https://openalex.org/I2800052317","display_name":"Kaplan Medical Center","ror":"https://ror.org/00t0n9020","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2800052317","https://openalex.org/I64767286"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"M Lahav","raw_affiliation_strings":["Emek Medical Center","Kaplan Medical Center Israel","Tel Aviv University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emek Medical Center","institution_ids":["https://openalex.org/I2799294462"]},{"raw_affiliation_string":"Kaplan Medical Center Israel","institution_ids":["https://openalex.org/I2800052317"]},{"raw_affiliation_string":"Tel Aviv University","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113540166","display_name":"Alan Berrebi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]},{"id":"https://openalex.org/I2799294462","display_name":"Emek Medical Center","ror":"https://ror.org/02b988t02","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799294462","https://openalex.org/I64767286"]},{"id":"https://openalex.org/I2800052317","display_name":"Kaplan Medical Center","ror":"https://ror.org/00t0n9020","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2800052317","https://openalex.org/I64767286"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"A Berebi","raw_affiliation_strings":["Emek Medical Center","Kaplan Medical Center Israel","Tel Aviv University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emek Medical Center","institution_ids":["https://openalex.org/I2799294462"]},{"raw_affiliation_string":"Kaplan Medical Center Israel","institution_ids":["https://openalex.org/I2800052317"]},{"raw_affiliation_string":"Tel Aviv University","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084290698","display_name":"Zeev E. Estrov","orcid":"https://orcid.org/0000-0002-1623-3613","observed_orcids":["https://orcid.org/0000-0002-1623-3613"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Z Estrov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074480359","display_name":"Sarit Zur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]},{"id":"https://openalex.org/I2799294462","display_name":"Emek Medical Center","ror":"https://ror.org/02b988t02","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799294462","https://openalex.org/I64767286"]},{"id":"https://openalex.org/I2800052317","display_name":"Kaplan Medical Center","ror":"https://ror.org/00t0n9020","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2800052317","https://openalex.org/I64767286"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"S Zur","raw_affiliation_strings":["Emek Medical Center","Kaplan Medical Center Israel","Tel Aviv University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emek Medical Center","institution_ids":["https://openalex.org/I2799294462"]},{"raw_affiliation_string":"Kaplan Medical Center Israel","institution_ids":["https://openalex.org/I2800052317"]},{"raw_affiliation_string":"Tel Aviv University","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009903878","display_name":"Peretz Resnitzky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]},{"id":"https://openalex.org/I2799294462","display_name":"Emek Medical Center","ror":"https://ror.org/02b988t02","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799294462","https://openalex.org/I64767286"]},{"id":"https://openalex.org/I2800052317","display_name":"Kaplan Medical Center","ror":"https://ror.org/00t0n9020","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2800052317","https://openalex.org/I64767286"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"P Resnitzky","raw_affiliation_strings":["Emek Medical Center","Kaplan Medical Center Israel","Tel Aviv University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emek Medical Center","institution_ids":["https://openalex.org/I2799294462"]},{"raw_affiliation_string":"Kaplan Medical Center Israel","institution_ids":["https://openalex.org/I2800052317"]},{"raw_affiliation_string":"Tel Aviv University","institution_ids":["https://openalex.org/I16391192"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.00316984,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"81","issue":"10","first_page":"995","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.7113999724388123,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.7113999724388123,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.24690000712871552,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.008200000040233135,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/waldenstrom-macroglobulinemia","display_name":"Waldenstr\u00f6m macroglobulinemia","score":0.9829999804496765},{"id":"https://openalex.org/keywords/iga-deficiency","display_name":"IgA deficiency","score":0.8149999976158142},{"id":"https://openalex.org/keywords/secretory-component","display_name":"secretory component","score":0.8379999995231628},{"id":"https://openalex.org/keywords/diarrhea","display_name":"diarrhea","score":0.8100000023841858},{"id":"https://openalex.org/keywords/steatorrhea","display_name":"steatorrhea","score":0.9829999804496765},{"id":"https://openalex.org/keywords/small-intestinal-bacterial-overgrowth","display_name":"small intestinal bacterial overgrowth","score":0.8989999890327454},{"id":"https://openalex.org/keywords/b-cell-lymphoproliferative-disorders","display_name":"B-cell lymphoproliferative disorders","score":0.703000009059906}],"concepts":[{"id":"https://openalex.org/C2776391228","wikidata":"https://www.wikidata.org/wiki/Q4118092","display_name":"Macroglobulinemia","level":3,"score":0.8620059490203857},{"id":"https://openalex.org/C2777675875","wikidata":"https://www.wikidata.org/wiki/Q1549428","display_name":"Steatorrhea","level":2,"score":0.8545762300491333},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8100899457931519},{"id":"https://openalex.org/C2779802037","wikidata":"https://www.wikidata.org/wiki/Q40878","display_name":"Diarrhea","level":2,"score":0.6876578330993652},{"id":"https://openalex.org/C2781038049","wikidata":"https://www.wikidata.org/wiki/Q1778287","display_name":"Waldenstrom macroglobulinemia","level":3,"score":0.6079404950141907},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5074371695518494},{"id":"https://openalex.org/C2779102806","wikidata":"https://www.wikidata.org/wiki/Q79453","display_name":"Immunoglobulin A","level":4,"score":0.4328669607639313},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3718819320201874},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.22072720527648926},{"id":"https://openalex.org/C2780898057","wikidata":"https://www.wikidata.org/wiki/Q79448","display_name":"Immunoglobulin G","level":3,"score":0.1047881543636322},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.09608548879623413},{"id":"https://openalex.org/C2776364478","wikidata":"https://www.wikidata.org/wiki/Q467635","display_name":"Multiple myeloma","level":2,"score":0.09245774149894714}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003967","descriptor_name":"Diarrhea","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D004406","descriptor_name":"Dysgammaglobulinemia","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007071","descriptor_name":"Immunoglobulin A, Secretory","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D007128","descriptor_name":"Immunoglobulin Fragments","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D008258","descriptor_name":"Waldenstrom Macroglobulinemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D008258","descriptor_name":"Waldenstrom Macroglobulinemia","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012635","descriptor_name":"Secretory Component","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D017098","descriptor_name":"IgA Deficiency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:3094364","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3094364","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Case Reports"},{"id":"mag:45728653","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3094364","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2400356499","https://openalex.org/W2032050282","https://openalex.org/W2920891187","https://openalex.org/W79122332","https://openalex.org/W2566776525","https://openalex.org/W2091046691","https://openalex.org/W4256154615","https://openalex.org/W4403720403","https://openalex.org/W2034049590","https://openalex.org/W2152579635"],"abstract_inverted_index":{"A":[0],"case":[1],"of":[2,57],"a":[3],"patient":[4],"suffering":[5],"from":[6],"Waldenstrom's":[7,60],"macroglobulinemia":[8],"who":[9],"developed":[10],"diarrhea":[11,58],"and":[12,27,46],"mild":[13],"steatorrhea":[14],"is":[15],"described.":[16],"Laboratory":[17],"studies":[18],"revealed":[19],"low":[20],"serum":[21],"IgA,":[22],"intestinal":[23],"secretory":[24,47],"IgA":[25,44],"deficiency,":[26],"small":[28],"intestine":[29],"bacterial":[30],"overgrowth":[31],"as":[32],"demonstrated":[33],"by":[34],"the":[35,55],"C14-cholylglycine":[36],"breath":[37],"test.":[38],"These":[39],"findings":[40],"suggest":[41],"that":[42],"selective":[43],"deficiency":[45,49],"component":[48],"may":[50],"be":[51],"contributing":[52],"factors":[53],"in":[54,59],"development":[56],"macroglobulinemia.":[61]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}