{"id":"https://openalex.org/W45524686","doi":null,"title":"Insulin pump treatment in children and adolescents with type 1 diabetes.","display_name":"Insulin pump treatment in children and adolescents with type 1 diabetes.","publication_year":2012,"publication_date":"2012-08-01","ids":{"openalex":"https://openalex.org/W45524686","mag":"45524686","pmid":"https://pubmed.ncbi.nlm.nih.gov/22728614"},"language":"en","primary_location":{"id":"pmid:22728614","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22728614","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva pediatrica","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050209368","display_name":"Sabine E. Hofer","orcid":"https://orcid.org/0000-0001-6778-0062","observed_orcids":["https://orcid.org/0000-0001-6778-0062"]},"institutions":[{"id":"https://openalex.org/I143397708","display_name":"Innsbruck Medical University","ror":"https://ror.org/03pt86f80","country_code":"AT","type":"education","lineage":["https://openalex.org/I143397708"]},{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"S Hofer","raw_affiliation_strings":["Department of Pediatrics. Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. Sabine.E.Hofer@i-med.ac.t"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics. Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. Sabine.E.Hofer@i-med.ac.t","institution_ids":["https://openalex.org/I143397708","https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068916463","display_name":"Dagmar Meraner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Meraner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5086054614","display_name":"Julia K\u00f6hle","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Koehle","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2357,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.78452302,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"64","issue":"4","first_page":"433","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10793","display_name":"Diabetes Management and Education","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/continuous-subcutaneous-insulin-infusion","display_name":"insulin pump therapy","score":0.9679999947547913},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9800000190734863},{"id":"https://openalex.org/keywords/children-and-adolescents","display_name":"children and adolescents","score":0.8740000128746033},{"id":"https://openalex.org/keywords/basal-insulin-rate","display_name":"basal insulin rate","score":0.6880000233650208},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.7409999966621399},{"id":"https://openalex.org/keywords/dawn-phenomenon","display_name":"dawn phenomenon","score":0.8769999742507935},{"id":"https://openalex.org/keywords/nocturnal-hypoglycemia","display_name":"nocturnal hypoglycemia","score":0.9850000143051147},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.9179999828338623},{"id":"https://openalex.org/keywords/ketoacidosis","display_name":"ketoacidosis","score":0.8220000267028809},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.7990000247955322},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.9490000009536743}],"concepts":[{"id":"https://openalex.org/C2779794567","wikidata":"https://www.wikidata.org/wiki/Q941674","display_name":"Insulin pump","level":4,"score":0.9530653953552246},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9201233386993408},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.7745958566665649},{"id":"https://openalex.org/C2778715236","wikidata":"https://www.wikidata.org/wiki/Q55622662","display_name":"Discontinuation","level":2,"score":0.7317190170288086},{"id":"https://openalex.org/C2781232474","wikidata":"https://www.wikidata.org/wiki/Q124407","display_name":"Type 1 diabetes","level":3,"score":0.685207724571228},{"id":"https://openalex.org/C2780668416","wikidata":"https://www.wikidata.org/wiki/Q202758","display_name":"Hypoglycemia","level":3,"score":0.6413668394088745},{"id":"https://openalex.org/C2780473172","wikidata":"https://www.wikidata.org/wiki/Q5572518","display_name":"Glycemic","level":3,"score":0.5745260119438171},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5430753231048584},{"id":"https://openalex.org/C2775849729","wikidata":"https://www.wikidata.org/wiki/Q1130148","display_name":"Ketoacidosis","level":4,"score":0.5159252882003784},{"id":"https://openalex.org/C2781283889","wikidata":"https://www.wikidata.org/wiki/Q1130148","display_name":"Diabetic ketoacidosis","level":3,"score":0.42242249846458435},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4080316424369812},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3996361494064331},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3436318635940552}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006442","descriptor_name":"Glycated Hemoglobin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007003","descriptor_name":"Hypoglycemia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D007332","descriptor_name":"Insulin Infusion Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015918","descriptor_name":"Infusion Pumps, Implantable","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055104","descriptor_name":"Infusions, Subcutaneous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:22728614","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22728614","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva pediatrica","raw_type":"Journal Article"},{"id":"mag:45524686","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22728614","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2013772536","https://openalex.org/W2116415328","https://openalex.org/W2100571124","https://openalex.org/W2062036789","https://openalex.org/W2143819158","https://openalex.org/W4396835906","https://openalex.org/W2022313153","https://openalex.org/W2402028589","https://openalex.org/W2065182422","https://openalex.org/W2764247723"],"abstract_inverted_index":{"Within":[0],"children":[1,102,196,240],"and":[2,23,28,91,103,121,133,161,173,212,214,241],"adolescents":[3,242],"with":[4,48,78,170,243],"type":[5,244],"1":[6,245],"diabetes":[7],"insulin":[8,17,38,61,98,148,156,180],"pump":[9,18,99,149,181,205,236],"treatment":[10,100,206,237],"is":[11,63,188],"of":[12,16,57,66,70,81,83,108,119,124,179,217,226,228,235],"increasing":[13],"interest.":[14],"Frequency":[15],"therapy":[19],"shows":[20],"a":[21,34,117],"rapid":[22,233],"steep":[24],"increase":[25,146,234],"in":[26,74,101,130,134,147,186,193,200,238],"toddlers":[27],"young":[29,76,195,239],"children.":[30],"Insulin":[31,204],"pumps":[32,62],"allow":[33],"close":[35],"to":[36,41,87,153,177,198,209],"physiologic":[37],"delivery":[39],"due":[40,152],"basal":[42],"rates":[43,85],"programmed":[44],"over":[45],"24":[46],"hours":[47],"circadian":[49],"rhythms":[50],"taken":[51],"into":[52],"account.":[53],"Furthermore,":[54],"another":[55],"advantage":[56],"technical":[58],"devices":[59,220],"as":[60,72,221,223],"the":[64,79,215,219,232],"application":[65],"extremely":[67],"small":[68],"amounts":[69],"insulin,":[71],"needed":[73],"very":[75,194],"children,":[77],"possibility":[80],"titration":[82],"infusion":[84],"down":[86],"0.01E/h.":[88],"Dawn":[89],"Phenomenon":[90],"hypoglycemic":[92],"events":[93],"are":[94,164],"main":[95],"indications":[96],"for":[97],"adolescents.":[104],"A":[105],"significant":[106],"reduction":[107,118],"severe":[109],"hypoglycemia,":[110],"especially":[111],"nocturnal":[112],"hypoglycemia":[113],"was":[114,207],"shown,":[115],"whereas":[116],"HbA1c":[120],"an":[122,224],"improvement":[123,225],"metabolic":[125],"control":[126,172],"has":[127],"been":[128],"reported":[129],"short":[131],"term":[132,140],"some":[135],"but":[136,166],"not":[137,145,168,175],"all":[138],"long":[139],"studies.":[141],"Ketoacidosis":[142],"rate":[143,185],"did":[144,174],"therapy.":[150],"Complications":[151],"continuous":[154],"subcutaneous":[155],"infusion,":[157],"like":[158],"local":[159],"infections":[160],"dermatological":[162],"changes":[163],"frequent":[165],"were":[167],"associated":[169],"glycemic":[171],"lead":[176],"discontinuation":[178,184],"treatment.":[182],"Pump":[183],"general":[187],"low,":[189],"varying":[190],"from":[191],"1%":[192],"up":[197],"6%":[199],"pubertal":[201],"adolescent":[202],"girls.":[203],"shown":[208],"be":[210],"safe":[211],"efficient":[213],"simplicity":[216],"handling":[218],"well":[222],"quality":[227],"life":[229],"may":[230],"explain":[231],"diabetes.":[246]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}