{"id":"https://openalex.org/W45225139","doi":null,"title":"Comparative tooth whitening and extrinsic tooth stain prevention efficacy of a new dentifrice and a commercially available tooth whitening dentifrice: six-week clinical trial.","display_name":"Comparative tooth whitening and extrinsic tooth stain prevention efficacy of a new dentifrice and a commercially available tooth whitening dentifrice: six-week clinical trial.","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W45225139","mag":"45225139","pmid":"https://pubmed.ncbi.nlm.nih.gov/15359544"},"language":"en","primary_location":{"id":"pmid:15359544","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15359544","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical dentistry","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Naresh Sharma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135004","display_name":"Colgate-Palmolive (United States)","ror":"https://ror.org/03q50jp21","country_code":"US","type":"company","lineage":["https://openalex.org/I4210135004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Naresh Sharma","raw_affiliation_strings":["Colgate-Palmolive Technology Center, Piscataway, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Colgate-Palmolive Technology Center, Piscataway, NJ, USA","institution_ids":["https://openalex.org/I4210135004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071140313","display_name":"H J Galustians","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Jack Galustians","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113896314","display_name":"Jimmy G. Qaqish","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jimmy Qaqish","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043915081","display_name":"K N Rustogi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kedar Rustogi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089865466","display_name":"Yun Po Zhang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yun Po Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057651210","display_name":"Margaret E Petrone","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Margaret E Petrone","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112138043","display_name":"William DeVizio","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William DeVizio","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5027934124","display_name":"Howard M. Proskin","orcid":"https://orcid.org/0000-0002-4278-2552","observed_orcids":["https://orcid.org/0000-0002-4278-2552"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Howard M Proskin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.00742207,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"15","issue":"2","first_page":"52","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11958","display_name":"Dental Erosion and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11958","display_name":"Dental Erosion and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tooth-bleaching","display_name":"tooth bleaching","score":0.8930000066757202},{"id":"https://openalex.org/keywords/whitening-dentifrice","display_name":"whitening dentifrice","score":0.8259999752044678},{"id":"https://openalex.org/keywords/extrinsic-tooth-stain","display_name":"extrinsic tooth stain","score":0.9169999957084656},{"id":"https://openalex.org/keywords/stain-prevention","display_name":"stain prevention","score":0.9070000052452087},{"id":"https://openalex.org/keywords/hydrogen-peroxide","display_name":"hydrogen peroxide","score":0.9789999723434448},{"id":"https://openalex.org/keywords/sodium-fluoride","display_name":"sodium fluoride","score":0.9940000176429749},{"id":"https://openalex.org/keywords/sodium-tripolyphosphate","display_name":"sodium tripolyphosphate","score":0.9959999918937683},{"id":"https://openalex.org/keywords/sodium-hexametaphosphate","display_name":"sodium hexametaphosphate","score":0.8199999928474426},{"id":"https://openalex.org/keywords/tooth-color","display_name":"tooth color","score":0.8659999966621399},{"id":"https://openalex.org/keywords/plaque-control","display_name":"plaque control","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C185017772","wikidata":"https://www.wikidata.org/wiki/Q5259487","display_name":"Dentifrice","level":3,"score":0.9828821420669556},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.8138559460639954},{"id":"https://openalex.org/C2777892068","wikidata":"https://www.wikidata.org/wiki/Q134205","display_name":"Toothbrush","level":3,"score":0.7719419002532959},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7644252777099609},{"id":"https://openalex.org/C2780262163","wikidata":"https://www.wikidata.org/wiki/Q143458","display_name":"Tooth whitening","level":2,"score":0.664968729019165},{"id":"https://openalex.org/C515851188","wikidata":"https://www.wikidata.org/wiki/Q13445028","display_name":"Oral hygiene","level":2,"score":0.5534548759460449},{"id":"https://openalex.org/C2909562476","wikidata":"https://www.wikidata.org/wiki/Q948056","display_name":"Tooth Sensitivity","level":2,"score":0.42693933844566345},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.33585354685783386},{"id":"https://openalex.org/C2780828025","wikidata":"https://www.wikidata.org/wiki/Q44793182","display_name":"Fluoride","level":2,"score":0.09431490302085876},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.07083693146705627},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C16108499","wikidata":"https://www.wikidata.org/wiki/Q1713927","display_name":"Brush","level":2,"score":0.0},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002327","descriptor_name":"Cariostatic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003802","descriptor_name":"Dentifrices","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010710","descriptor_name":"Phosphates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011122","descriptor_name":"Polyphosphates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D012822","descriptor_name":"Silicon Dioxide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D012969","descriptor_name":"Sodium Fluoride","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D014070","descriptor_name":"Tooth","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014073","descriptor_name":"Tooth Bleaching","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D014075","descriptor_name":"Tooth Discoloration","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D014099","descriptor_name":"Toothbrushing","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D014099","descriptor_name":"Toothbrushing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016037","descriptor_name":"Single-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016877","descriptor_name":"Oxidants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:15359544","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15359544","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical dentistry","raw_type":"Clinical Trial"},{"id":"mag:45225139","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15359544","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9907000064849854,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2419742606","https://openalex.org/W45522690","https://openalex.org/W170451954","https://openalex.org/W88840239","https://openalex.org/W182868765","https://openalex.org/W62180007","https://openalex.org/W2409945823","https://openalex.org/W2760841199","https://openalex.org/W187225822","https://openalex.org/W111079534"],"abstract_inverted_index":{"OBJECTIVE:":[0],"The":[1,94],"objective":[2],"of":[3,20,44,64,122,170,185,208,220,222,324,332],"this":[4],"six-week,":[5],"examiner-blind":[6],"clinical":[7],"study":[8],"was":[9],"to":[10,42,138,156,260,286],"assess":[11],"the":[12,78,87,152,166,171,183,186,232,236,241,246,261,267,272,287,337],"tooth":[13,66,69,104,107,192,195,256,282,328,334],"whitening":[14,49,283,301,329],"and":[15,31,62,68,74,106,116,126,148,155,194,205,216,234,243,269,292,310,330],"extrinsic":[16,65,103,191,333],"stain":[17,67,193,257,335],"prevention":[18,331],"efficacy":[19,325],"a":[21,35,45,56,113,120,127,218,314,319],"new":[22,300],"dentifrice":[23,50,153],"delivering":[24,303],"1.0%":[25,304],"hydrogen":[26,305],"peroxide,":[27,306],"0.243%":[28,307],"sodium":[29,32,308,311],"fluoride,":[30,309],"tripolyphosphate":[33,312],"in":[34,313],"high-cleaning":[36,315],"silica":[37,316],"base":[38,317],"(Test":[39],"Dentifrice)":[40],"relative":[41],"that":[43],"commercially":[46,338],"available":[47,339],"hexametaphosphate-containing":[48],"(Positive":[51],"Control":[52,91,263,289,341],"Dentifrice).":[53],"METHODOLOGY:":[54],"Following":[55],"baseline":[57],"oral":[58,162],"soft":[59,189],"tissue":[60],"examination":[61],"scoring":[63],"shade,":[70],"qualifying":[71],"adult":[72,129],"male":[73],"female":[75],"subjects":[76,111,229],"from":[77,158],"Mississauga,":[79],"Ontario,":[80],"Canada":[81],"area":[82],"were":[83,97,117,136,174,201,214],"randomized":[84],"into":[85],"either":[86],"Test":[88,247,273],"or":[89,179],"Positive":[90,262,288,340],"Dentifrice":[92,248,274,290],"group.":[93],"two":[95,143,204],"groups":[96],"balanced":[98],"for":[99,131,142,165,198,326],"age,":[100],"tobacco":[101],"use,":[102],"stain,":[105],"shade":[108,196,294],"scores.":[109],"All":[110,211],"received":[112],"dental":[114],"prophylaxis,":[115],"provided":[118,275],"with":[119,231],"supply":[121],"their":[123,140],"assigned":[124],"product":[125,209],"soft-bristled":[128],"toothbrush":[130],"use":[132],"at":[133,266],"home.":[134],"Subjects":[135],"instructed":[137],"brush":[139],"teeth":[141],"minutes":[144],"twice":[145],"daily":[146],"(morning":[147],"evening)":[149],"using":[150,159],"only":[151],"provided,":[154],"refrain":[157],"any":[160],"other":[161],"hygiene":[163],"products":[164],"entire":[167,237],"six":[168,206],"weeks":[169,207],"study.":[172,187,238],"There":[173],"no":[175],"restrictions":[176],"regarding":[177],"diet":[178],"smoking":[180],"habits":[181],"during":[182],"course":[184],"Oral":[188],"tissue,":[190],"assessments":[197],"each":[199],"subject":[200],"repeated":[202],"after":[203],"use.":[210],"statistical":[212],"tests":[213],"two-sided":[215],"employed":[217],"level":[219,323],"significance":[221],"alpha":[223],"=":[224],"0.05.":[225],"RESULTS:":[226],"Seventy-six":[227],"(76)":[228],"complied":[230],"protocol":[233],"completed":[235],"At":[239],"both":[240,327],"two-week":[242,268],"six-week":[244,270],"examinations,":[245,271],"prevented":[249],"statistically":[250,276,320],"significant":[251,277,321],"(p":[252,278],"<":[253,279],"0.05)":[254,280],"more":[255],"as":[258,284],"compared":[259,285],"Dentifrice.":[264,342],"Also,":[265],"greater":[281,322],"(2.64":[291],"3.77":[293],"rank":[295],"reductions,":[296],"respectively).":[297],"CONCLUSION:":[298],"A":[299],"dentifrice,":[302],"provides":[318],"than":[336]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}