{"id":"https://openalex.org/W4417469737","doi":"https://doi.org/10.7759/cureus.99555","title":"Hypertensive Emergency Presenting With Isolated Cranial Nerve III Palsy and Subsequent Intracranial Hemorrhage","display_name":"Hypertensive Emergency Presenting With Isolated Cranial Nerve III Palsy and Subsequent Intracranial Hemorrhage","publication_year":2025,"publication_date":"2025-12-18","ids":{"openalex":"https://openalex.org/W4417469737","doi":"https://doi.org/10.7759/cureus.99555","pmid":"https://pubmed.ncbi.nlm.nih.gov/41552111"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.99555","doi":"https://doi.org/10.7759/cureus.99555","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.99555","pdf_url":"https://www.cureus.com/articles/439011-hypertensive-emergency-presenting-with-isolated-cranial-nerve-iii-palsy-and-subsequent-intracranial-hemorrhage.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.cureus.com/articles/439011-hypertensive-emergency-presenting-with-isolated-cranial-nerve-iii-palsy-and-subsequent-intracranial-hemorrhage.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5120846976","display_name":"Mohammed Khaleefah","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohammed Khaleefah","raw_affiliation_strings":["Family Medicine, Chino Valley Medical Center, Chino, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Family Medicine, Chino Valley Medical Center, Chino, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112969879","display_name":"David Parvizi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Parvizi","raw_affiliation_strings":["Family Medicine, Chino Valley Medical Center, Chino, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Family Medicine, Chino Valley Medical Center, Chino, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120846977","display_name":"Huda Nasani","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Huda Nasani","raw_affiliation_strings":["Family Medicine, Chino Valley Medical Center, Chino, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Family Medicine, Chino Valley Medical Center, Chino, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dylan Begun","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dylan Begun","raw_affiliation_strings":["Family Medicine, Chino Valley Medical Center, Chino, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Family Medicine, Chino Valley Medical Center, Chino, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kim Nguyen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kim Nguyen","raw_affiliation_strings":["Family Medicine, Chino Valley Medical Center, chino, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Family Medicine, Chino Valley Medical Center, chino, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119200957","display_name":"Marco Valladres","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marco Valladres","raw_affiliation_strings":["Family Medicine, Chino Valley Medical Center, Chino, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Family Medicine, Chino Valley Medical Center, Chino, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Huyen Tran","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Huyen Tran","raw_affiliation_strings":["Family Medicine, Chino Valley Medical Center, Chino, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Family Medicine, Chino Valley Medical Center, Chino, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5119200958","display_name":"Jhoette Dumlao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jhoette Dumlao","raw_affiliation_strings":["Family Medicine, Chino Valley Medical Center, Chino, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Family Medicine, Chino Valley Medical Center, Chino, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.36264163,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":"12","first_page":"e99555","last_page":"e99555"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":0.6021000146865845,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":0.6021000146865845,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications","score":0.2870999872684479,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":0.07209999859333038,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypertensive-emergency","display_name":"hypertensive emergency","score":0.9940000176429749},{"id":"https://openalex.org/keywords/oculomotor-nerve-palsy","display_name":"oculomotor nerve palsy","score":0.9369999766349792},{"id":"https://openalex.org/keywords/intracranial-hemorrhage","display_name":"intracranial hemorrhage","score":0.9620000123977661},{"id":"https://openalex.org/keywords/hypertensive-encephalopathy","display_name":"hypertensive encephalopathy","score":0.8970000147819519},{"id":"https://openalex.org/keywords/carotid-stenosis","display_name":"carotid artery stenosis","score":0.8569999933242798},{"id":"https://openalex.org/keywords/aneurysm-rupture","display_name":"aneurysm rupture","score":0.8349999785423279},{"id":"https://openalex.org/keywords/atypical-presentation","display_name":"atypical presentation","score":0.6759999990463257},{"id":"https://openalex.org/keywords/antihypertensive-therapy","display_name":"antihypertensive therapy","score":0.796999990940094},{"id":"https://openalex.org/keywords/cardiac-arrest","display_name":"cardiac arrest","score":0.722000002861023}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9810000061988831},{"id":"https://openalex.org/C2776385636","wikidata":"https://www.wikidata.org/wiki/Q1641132","display_name":"Hypertensive emergency","level":3,"score":0.6937000155448914},{"id":"https://openalex.org/C2778097013","wikidata":"https://www.wikidata.org/wiki/Q68212673","display_name":"Palsy","level":3,"score":0.5813999772071838},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.5163999795913696},{"id":"https://openalex.org/C3019477908","wikidata":"https://www.wikidata.org/wiki/Q5182126","display_name":"Cranial nerve palsy","level":2,"score":0.4936999976634979},{"id":"https://openalex.org/C2780724011","wikidata":"https://www.wikidata.org/wiki/Q1295316","display_name":"Emergency department","level":2,"score":0.4729999899864197},{"id":"https://openalex.org/C2777094939","wikidata":"https://www.wikidata.org/wiki/Q1368943","display_name":"Intracerebral hemorrhage","level":3,"score":0.4544000029563904},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4449000060558319},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4074000120162964},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.4074000120162964},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.39559999108314514},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.38769999146461487},{"id":"https://openalex.org/C146638467","wikidata":"https://www.wikidata.org/wiki/Q10529587","display_name":"Hyperintensity","level":3,"score":0.3871000111103058},{"id":"https://openalex.org/C2778034410","wikidata":"https://www.wikidata.org/wiki/Q180454","display_name":"Cranial nerves","level":2,"score":0.3862000107765198},{"id":"https://openalex.org/C520017518","wikidata":"https://www.wikidata.org/wiki/Q178934","display_name":"Occult","level":3,"score":0.36959999799728394},{"id":"https://openalex.org/C2780168130","wikidata":"https://www.wikidata.org/wiki/Q2916167","display_name":"Neurological examination","level":2,"score":0.35830000042915344},{"id":"https://openalex.org/C2779949217","wikidata":"https://www.wikidata.org/wiki/Q4138746","display_name":"Hypertensive encephalopathy","level":3,"score":0.3578999936580658},{"id":"https://openalex.org/C2779211832","wikidata":"https://www.wikidata.org/wiki/Q1670952","display_name":"Oculomotor nerve palsy","level":4,"score":0.35580000281333923},{"id":"https://openalex.org/C2780505380","wikidata":"https://www.wikidata.org/wiki/Q7142931","display_name":"Past medical history","level":2,"score":0.33739998936653137},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.33169999718666077},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.32850000262260437},{"id":"https://openalex.org/C2778212899","wikidata":"https://www.wikidata.org/wiki/Q907325","display_name":"Magnetic resonance angiography","level":3,"score":0.3278999924659729},{"id":"https://openalex.org/C2776098176","wikidata":"https://www.wikidata.org/wiki/Q189389","display_name":"Aneurysm","level":2,"score":0.3188999891281128},{"id":"https://openalex.org/C2780268429","wikidata":"https://www.wikidata.org/wiki/Q318773","display_name":"Abducens nerve","level":4,"score":0.3188000023365021},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.3066999912261963},{"id":"https://openalex.org/C206179267","wikidata":"https://www.wikidata.org/wiki/Q188952","display_name":"Medical history","level":2,"score":0.3052000105381012},{"id":"https://openalex.org/C2778749279","wikidata":"https://www.wikidata.org/wiki/Q5064095","display_name":"Cerebral angiography","level":3,"score":0.289000004529953},{"id":"https://openalex.org/C527108885","wikidata":"https://www.wikidata.org/wiki/Q835153","display_name":"Physical examination","level":2,"score":0.2822999954223633},{"id":"https://openalex.org/C2778879792","wikidata":"https://www.wikidata.org/wiki/Q1126769","display_name":"Paresis","level":2,"score":0.2797999978065491},{"id":"https://openalex.org/C2776559263","wikidata":"https://www.wikidata.org/wiki/Q5182126","display_name":"Cranial nerve disease","level":3,"score":0.275299996137619},{"id":"https://openalex.org/C2778187257","wikidata":"https://www.wikidata.org/wiki/Q464210","display_name":"Basal ganglia","level":3,"score":0.26899999380111694},{"id":"https://openalex.org/C2779662492","wikidata":"https://www.wikidata.org/wiki/Q468787","display_name":"Hematoma","level":2,"score":0.2676999866962433},{"id":"https://openalex.org/C2777507709","wikidata":"https://www.wikidata.org/wiki/Q121576","display_name":"Vascular malformation","level":2,"score":0.265500009059906},{"id":"https://openalex.org/C2780317758","wikidata":"https://www.wikidata.org/wiki/Q3339235","display_name":"Neurological disorder","level":3,"score":0.25870001316070557},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.25780001282691956},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.2565999925136566},{"id":"https://openalex.org/C2779603958","wikidata":"https://www.wikidata.org/wiki/Q1584110","display_name":"Arteriovenous malformation","level":2,"score":0.2563000023365021}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.7759/cureus.99555","doi":"https://doi.org/10.7759/cureus.99555","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.99555","pdf_url":"https://www.cureus.com/articles/439011-hypertensive-emergency-presenting-with-isolated-cranial-nerve-iii-palsy-and-subsequent-intracranial-hemorrhage.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},{"id":"pmid:41552111","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41552111","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:12812021","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12812021/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cureus","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.7759/cureus.99555","doi":"https://doi.org/10.7759/cureus.99555","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.99555","pdf_url":"https://www.cureus.com/articles/439011-hypertensive-emergency-presenting-with-isolated-cranial-nerve-iii-palsy-and-subsequent-intracranial-hemorrhage.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"sustainable_development_goals_aurora":[],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4417469737.pdf","grobid_xml":"https://content.openalex.org/works/W4417469737.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W54671302","https://openalex.org/W2025854124","https://openalex.org/W2031403017","https://openalex.org/W2174783839","https://openalex.org/W2886517507","https://openalex.org/W3006303494","https://openalex.org/W3044491163","https://openalex.org/W3194540869","https://openalex.org/W3200287153","https://openalex.org/W3205652290","https://openalex.org/W4383621340","https://openalex.org/W4387976365","https://openalex.org/W4401024406","https://openalex.org/W4411465125","https://openalex.org/W4414380357"],"related_works":[],"abstract_inverted_index":{"Hypertensive":[0],"emergencies":[1],"present":[2,41],"as":[3],"a":[4,37,42,45,49,66,80,135,140,154],"life-threatening":[5],"condition":[6],"characterized":[7],"by":[8],"severely":[9],"elevated":[10],"blood":[11],"pressure":[12],"with":[13,48,65,114,139,145,151,172],"evidence":[14,101],"of":[15,44,51,69,95,102,153,169,183,195,206],"acute":[16],"end-organ":[17],"damage.":[18],"The":[19],"most":[20,149],"common":[21],"neurological":[22,126,208],"presentations":[23,198],"include":[24],"ischemic":[25],"stroke,":[26],"encephalopathy,":[27],"and":[28,73,109,128,179,204],"intracranial":[29,137],"hemorrhage;":[30],"however,":[31],"isolated":[32,174],"cranial":[33,82,175],"nerve":[34,83,176],"palsies":[35],"are":[36],"rare":[38],"occurrence.":[39],"We":[40],"case":[43,164],"72-year-old":[46],"female":[47],"history":[50,68],"chronic":[52],"hypertension":[53],"who":[54],"presented":[55],"to":[56],"the":[57,96,121,146,181],"emergency":[58,171],"department":[59],"at":[60],"Chino":[61],"Valley":[62],"Medical":[63],"Center":[64],"one-week":[67],"malaise,":[70],"headache,":[71],"hypertension,":[72],"right":[74],"eye":[75],"pain.":[76],"She":[77],"subsequently":[78],"developed":[79],"right-sided":[81],"III":[84,177],"palsy":[85,178],"during":[86],"hospitalization.":[87],"CT":[88,132],"angiography":[89],"demonstrated":[90],"greater":[91],"than":[92],"90%":[93],"stenosis":[94],"left":[97],"carotid":[98],"bulb":[99],"without":[100],"aneurysm.":[103],"MRI":[104],"showed":[105],"bilateral":[106],"basal":[107],"ganglia":[108],"thalamic":[110],"T2":[111],"hyperintensities":[112],"consistent":[113,150],"hypertensive":[115,170],"encephalopathy.":[116],"Despite":[117],"escalating":[118],"antihypertensive":[119],"therapy,":[120],"patient":[122],"experienced":[123],"an":[124,166,173],"abrupt":[125],"decline":[127],"cardiopulmonary":[129],"arrest.":[130],"Repeat":[131],"imaging":[133,191],"revealed":[134],"multi-compartment":[136],"hemorrhage":[138,147],"10":[141],"mm":[142],"midline":[143],"shift,":[144],"pattern":[148],"rupture":[152],"previously":[155],"occult":[156],"aneurysm":[157],"not":[158],"visualized":[159],"on":[160],"initial":[161],"CTA.":[162],"This":[163],"highlights":[165],"atypical":[167,197],"presentation":[168],"underscores":[180],"importance":[182],"considering":[184],"aneurysmal":[185],"pathology":[186],"even":[187],"when":[188],"early":[189],"vascular":[190],"is":[192,199],"unrevealing.":[193],"Recognition":[194],"such":[196],"critical":[200],"for":[201],"timely":[202],"diagnosis":[203],"prevention":[205],"devastating":[207],"outcomes.":[209]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2025-12-18T00:00:00"}