{"id":"https://openalex.org/W4417448679","doi":"https://doi.org/10.1186/s12864-025-12414-y","title":"Anuran genome size evolution is driven by relatively recent retrotransposon activity and by life history","display_name":"Anuran genome size evolution is driven by relatively recent retrotransposon activity and by life history","publication_year":2025,"publication_date":"2025-12-18","ids":{"openalex":"https://openalex.org/W4417448679","doi":"https://doi.org/10.1186/s12864-025-12414-y","pmid":"https://pubmed.ncbi.nlm.nih.gov/41413442","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12822217"},"language":"en","primary_location":{"id":"doi:10.1186/s12864-025-12414-y","doi":"https://doi.org/10.1186/s12864-025-12414-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12864-025-12414-y","pdf_url":null,"source":{"id":"https://openalex.org/S28614077","display_name":"BMC Genomics","issn_l":"1471-2164","issn":["1471-2164"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12864-025-12414-y","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022832809","display_name":"Andrew O. Rubio","orcid":"https://orcid.org/0000-0001-9273-4199","observed_orcids":["https://orcid.org/0000-0001-9273-4199"]},"institutions":[{"id":"https://openalex.org/I44461941","display_name":"University of Houston","ror":"https://ror.org/048sx0r50","country_code":"US","type":"education","lineage":["https://openalex.org/I44461941"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Andrew O. Rubio","raw_affiliation_strings":["Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA. andreworubio@gmail.com","Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA"],"raw_orcid":"https://orcid.org/0000-0001-9273-4199","affiliations":[{"raw_affiliation_string":"Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA. andreworubio@gmail.com","institution_ids":["https://openalex.org/I44461941"]},{"raw_affiliation_string":"Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA","institution_ids":["https://openalex.org/I44461941"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084802442","display_name":"John H. Neddermeyer","orcid":"https://orcid.org/0000-0001-6584-7905","observed_orcids":["https://orcid.org/0000-0001-6584-7905"]},"institutions":[{"id":"https://openalex.org/I203172682","display_name":"Northern Arizona University","ror":"https://ror.org/0272j5188","country_code":"US","type":"education","lineage":["https://openalex.org/I203172682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John H. Neddermeyer","raw_affiliation_strings":["School of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, AZ, 86011, USA"],"raw_orcid":"https://orcid.org/0000-0001-6584-7905","affiliations":[{"raw_affiliation_string":"School of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, AZ, 86011, USA","institution_ids":["https://openalex.org/I203172682"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Aakash James","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44461941","display_name":"University of Houston","ror":"https://ror.org/048sx0r50","country_code":"US","type":"education","lineage":["https://openalex.org/I44461941"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aakash James","raw_affiliation_strings":["Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA","institution_ids":["https://openalex.org/I44461941"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nicholas Janz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44461941","display_name":"University of Houston","ror":"https://ror.org/048sx0r50","country_code":"US","type":"education","lineage":["https://openalex.org/I44461941"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicholas Janz","raw_affiliation_strings":["Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA","institution_ids":["https://openalex.org/I44461941"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002775614","display_name":"Jonathan A. Rader","orcid":"https://orcid.org/0000-0003-2419-3399","observed_orcids":["https://orcid.org/0000-0003-2419-3399"]},"institutions":[{"id":"https://openalex.org/I131740757","display_name":"Texas A&M International University","ror":"https://ror.org/028861t28","country_code":"US","type":"education","lineage":["https://openalex.org/I131740757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan A. Rader","raw_affiliation_strings":["Department of Biology and Chemistry, Texas A&M International University, Laredo, TX, 78041, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology and Chemistry, Texas A&M International University, Laredo, TX, 78041, USA","institution_ids":["https://openalex.org/I131740757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085834854","display_name":"Marc Tollis","orcid":"https://orcid.org/0000-0002-1917-2473","observed_orcids":["https://orcid.org/0000-0002-1917-2473"]},"institutions":[{"id":"https://openalex.org/I203172682","display_name":"Northern Arizona University","ror":"https://ror.org/0272j5188","country_code":"US","type":"education","lineage":["https://openalex.org/I203172682"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Marc Tollis","raw_affiliation_strings":["School of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, AZ, 86011, USA. marc.tollis@nau.edu","School of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, AZ, 86011, USA"],"raw_orcid":"https://orcid.org/0000-0002-1917-2473","affiliations":[{"raw_affiliation_string":"School of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, AZ, 86011, USA. marc.tollis@nau.edu","institution_ids":["https://openalex.org/I203172682"]},{"raw_affiliation_string":"School of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, AZ, 86011, USA","institution_ids":["https://openalex.org/I203172682"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008222699","display_name":"Adam M. M. Stuckert","orcid":"https://orcid.org/0000-0003-2250-2223","observed_orcids":["https://orcid.org/0000-0003-2250-2223"]},"institutions":[{"id":"https://openalex.org/I44461941","display_name":"University of Houston","ror":"https://ror.org/048sx0r50","country_code":"US","type":"education","lineage":["https://openalex.org/I44461941"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Adam M. M. Stuckert","raw_affiliation_strings":["Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA. astuckert@uh.edu","Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA. astuckert@uh.edu","institution_ids":["https://openalex.org/I44461941"]},{"raw_affiliation_string":"Department of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA","institution_ids":["https://openalex.org/I44461941"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5008222699","https://openalex.org/A5022832809","https://openalex.org/A5085834854"],"corresponding_institution_ids":["https://openalex.org/I203172682","https://openalex.org/I44461941"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":{"value":3090,"currency":"USD","value_usd":3090},"fwci":0.8551,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.73483694,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":96},"biblio":{"volume":"27","issue":"1","first_page":"74","last_page":"74"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13664","display_name":"Genome Rearrangement Algorithms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genome-size-evolution","display_name":"genome size evolution","score":0.9190000295639038},{"id":"https://openalex.org/keywords/transposable-elements","display_name":"transposable elements","score":0.8949999809265137},{"id":"https://openalex.org/keywords/retrotransposons","display_name":"retrotransposons","score":0.984000027179718},{"id":"https://openalex.org/keywords/anura","display_name":"Anura","score":0.8529999852180481},{"id":"https://openalex.org/keywords/ty1-copia","display_name":"Ty1-copia","score":0.8460000157356262},{"id":"https://openalex.org/keywords/piggybac","display_name":"piggyBac","score":0.8240000009536743},{"id":"https://openalex.org/keywords/sines","display_name":"SINEs","score":0.984000027179718},{"id":"https://openalex.org/keywords/larval-period","display_name":"larval period","score":0.6970000267028809},{"id":"https://openalex.org/keywords/clutch-size","display_name":"clutch size","score":0.9120000004768372},{"id":"https://openalex.org/keywords/life-history","display_name":"life history","score":0.7300000190734863},{"id":"https://openalex.org/keywords/transposable-element-copy-number","display_name":"transposable element copy number","score":0.7089999914169312},{"id":"https://openalex.org/keywords/phylogenetic-constraints","display_name":"phylogenetic constraints","score":0.6430000066757202}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8672000169754028},{"id":"https://openalex.org/C7029365","wikidata":"https://www.wikidata.org/wiki/Q413988","display_name":"Retrotransposon","level":5,"score":0.8648999929428101},{"id":"https://openalex.org/C61271108","wikidata":"https://www.wikidata.org/wiki/Q3180866","display_name":"Genome size","level":4,"score":0.8564000129699707},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.8431000113487244},{"id":"https://openalex.org/C4918238","wikidata":"https://www.wikidata.org/wiki/Q121438","display_name":"Transposable element","level":4,"score":0.6384999752044678},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.6284999847412109},{"id":"https://openalex.org/C174600577","wikidata":"https://www.wikidata.org/wiki/Q5533491","display_name":"Genome evolution","level":4,"score":0.6177999973297119},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5857999920845032},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4456999897956848},{"id":"https://openalex.org/C68873052","wikidata":"https://www.wikidata.org/wiki/Q349856","display_name":"Genetic variation","level":3,"score":0.41990000009536743},{"id":"https://openalex.org/C66698415","wikidata":"https://www.wikidata.org/wiki/Q1139127","display_name":"Life history theory","level":3,"score":0.3815000057220459},{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.3686999976634979},{"id":"https://openalex.org/C163096569","wikidata":"https://www.wikidata.org/wiki/Q16966366","display_name":"Gene density","level":5,"score":0.36000001430511475},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.33500000834465027},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.33059999346733093},{"id":"https://openalex.org/C65532224","wikidata":"https://www.wikidata.org/wiki/Q17081090","display_name":"Avian clutch size","level":3,"score":0.32420000433921814},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.30390000343322754},{"id":"https://openalex.org/C42251679","wikidata":"https://www.wikidata.org/wiki/Q933491","display_name":"GC-content","level":4,"score":0.29179999232292175},{"id":"https://openalex.org/C120821319","wikidata":"https://www.wikidata.org/wiki/Q1501491","display_name":"Copy-number variation","level":4,"score":0.2815000116825104},{"id":"https://openalex.org/C2781162219","wikidata":"https://www.wikidata.org/wiki/Q26250693","display_name":"Replicate","level":2,"score":0.2808000147342682},{"id":"https://openalex.org/C136397037","wikidata":"https://www.wikidata.org/wiki/Q33753","display_name":"Metamorphosis","level":3,"score":0.2775000035762787},{"id":"https://openalex.org/C2778334786","wikidata":"https://www.wikidata.org/wiki/Q1586270","display_name":"Variation (astronomy)","level":2,"score":0.27559998631477356},{"id":"https://openalex.org/C3641667","wikidata":"https://www.wikidata.org/wiki/Q1295959","display_name":"Effective population size","level":4,"score":0.27090001106262207},{"id":"https://openalex.org/C192953774","wikidata":"https://www.wikidata.org/wiki/Q7307127","display_name":"Reference genome","level":4,"score":0.2639000117778778},{"id":"https://openalex.org/C18949551","wikidata":"https://www.wikidata.org/wiki/Q740578","display_name":"Sequence assembly","level":5,"score":0.2558000087738037},{"id":"https://openalex.org/C87590526","wikidata":"https://www.wikidata.org/wiki/Q3592884","display_name":"Experimental evolution","level":3,"score":0.2556999921798706},{"id":"https://openalex.org/C517289559","wikidata":"https://www.wikidata.org/wiki/Q10297573","display_name":"Demographic history","level":4,"score":0.2524000108242035}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001001","descriptor_name":"Anura","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001001","descriptor_name":"Anura","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018626","descriptor_name":"Retroelements","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059646","descriptor_name":"Genome Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12864-025-12414-y","doi":"https://doi.org/10.1186/s12864-025-12414-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12864-025-12414-y","pdf_url":null,"source":{"id":"https://openalex.org/S28614077","display_name":"BMC Genomics","issn_l":"1471-2164","issn":["1471-2164"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-6941224/v1","doi":"https://doi.org/10.21203/rs.3.rs-6941224/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-6941224/v1","pdf_url":"https://www.researchsquare.com/article/rs-6941224/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmid:41413442","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41413442","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC genomics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12822217","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12822217/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12864-025-12414-y","doi":"https://doi.org/10.1186/s12864-025-12414-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12864-025-12414-y","pdf_url":null,"source":{"id":"https://openalex.org/S28614077","display_name":"BMC Genomics","issn_l":"1471-2164","issn":["1471-2164"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1371419766","display_name":"Collaborative Research: EDGE CMT: A four-dimensional genotype-phenotype map of poison frog skin color","funder_award_id":"2319712","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G729049606","display_name":"Collaborative Research: The Genomic Basis of Evolutionary Innovations in the Squamate Tree of Life","funder_award_id":"2323124","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4417448679.pdf","grobid_xml":"https://content.openalex.org/works/W4417448679.grobid-xml"},"referenced_works_count":91,"referenced_works":["https://openalex.org/W221200352","https://openalex.org/W1604908165","https://openalex.org/W1605984840","https://openalex.org/W1623913395","https://openalex.org/W1696515309","https://openalex.org/W1979592281","https://openalex.org/W1985395220","https://openalex.org/W1988714210","https://openalex.org/W1990221500","https://openalex.org/W1990519804","https://openalex.org/W1996088447","https://openalex.org/W2000585348","https://openalex.org/W2002260721","https://openalex.org/W2031468131","https://openalex.org/W2038399228","https://openalex.org/W2046916764","https://openalex.org/W2048540261","https://openalex.org/W2051541780","https://openalex.org/W2054373621","https://openalex.org/W2058402457","https://openalex.org/W2059864757","https://openalex.org/W2064155145","https://openalex.org/W2065461553","https://openalex.org/W2088306370","https://openalex.org/W2100860862","https://openalex.org/W2106389870","https://openalex.org/W2110065044","https://openalex.org/W2114525641","https://openalex.org/W2120868323","https://openalex.org/W2124726310","https://openalex.org/W2133360663","https://openalex.org/W2133537571","https://openalex.org/W2137455182","https://openalex.org/W2142466527","https://openalex.org/W2154435565","https://openalex.org/W2159186995","https://openalex.org/W2163985885","https://openalex.org/W2528422366","https://openalex.org/W2531278534","https://openalex.org/W2564972022","https://openalex.org/W2587213787","https://openalex.org/W2766160192","https://openalex.org/W2767660457","https://openalex.org/W2786089085","https://openalex.org/W2787061375","https://openalex.org/W2800905131","https://openalex.org/W2883251903","https://openalex.org/W2892635007","https://openalex.org/W2901318957","https://openalex.org/W2915094182","https://openalex.org/W2922333923","https://openalex.org/W2931393048","https://openalex.org/W2942815991","https://openalex.org/W2969926818","https://openalex.org/W2977738920","https://openalex.org/W2980195729","https://openalex.org/W2981796144","https://openalex.org/W2982615442","https://openalex.org/W2995761200","https://openalex.org/W3015934849","https://openalex.org/W3017049640","https://openalex.org/W3023483936","https://openalex.org/W3023538914","https://openalex.org/W3048222127","https://openalex.org/W3119908887","https://openalex.org/W3135161291","https://openalex.org/W3143063265","https://openalex.org/W3166508821","https://openalex.org/W3172646184","https://openalex.org/W4213026783","https://openalex.org/W4220919680","https://openalex.org/W4239678514","https://openalex.org/W4281758017","https://openalex.org/W4282049874","https://openalex.org/W4290075586","https://openalex.org/W4291000053","https://openalex.org/W4307511253","https://openalex.org/W4367173711","https://openalex.org/W4386157159","https://openalex.org/W4386170579","https://openalex.org/W4400353742","https://openalex.org/W4400843117","https://openalex.org/W4401722676","https://openalex.org/W4403136059","https://openalex.org/W4403883500","https://openalex.org/W4407688893","https://openalex.org/W4409344035","https://openalex.org/W4410112181","https://openalex.org/W4411494837","https://openalex.org/W7075681496","https://openalex.org/W7075735698"],"related_works":["https://openalex.org/W7125365957","https://openalex.org/W4383370111","https://openalex.org/W2263391408","https://openalex.org/W2931393048","https://openalex.org/W2922333923","https://openalex.org/W3135687004","https://openalex.org/W1597884192","https://openalex.org/W3023483936","https://openalex.org/W2914359001","https://openalex.org/W2293840722"],"abstract_inverted_index":{"BACKGROUND:":[0],"Transposable":[1],"elements":[2,199],"(TEs),":[3],"often":[4],"referred":[5],"to":[6,16,27,74,121,140,153,176],"as":[7],"\u2018selfish":[8],"genetic":[9,14],"elements\u2019,":[10],"hijack":[11],"their":[12],"host\u2019s":[13],"machinery":[15],"replicate":[17],"themselves":[18],"within":[19],"the":[20,78,123,128,145,223,251,254,302,307],"host":[21],"genome,":[22],"and":[23,35,80,100,184,200,271,273,288,317],"are":[24,39,101,187,211,231],"primary":[25],"contributors":[26],"genome":[28,97,115,132,160,180,215,235,256,286,322],"size":[29,56,69,98,161,216,252,287,323],"in":[30,55,68,72,77,144,151,163,320],"vertebrates.":[31],"In":[32,87,134],"particular,":[33],"frogs":[34],"toads":[36],"(Order:":[37],"Anura)":[38],"well":[40],"known":[41],"for":[42,49],"not":[43],"only":[44],"having":[45,50],"large":[46],"genomes,":[47],"but":[48],"genomes":[51],"with":[52,189,213,233,290],"drastic":[53],"variation":[54,99,162],"(e.g.,":[57],"Scaphiopus":[58],"couchii:":[59],"0.48":[60],"Gbp,":[61],"Rana":[62],"muscosa":[63],"10":[64],"Gbp).":[65],"This":[66],"discrepancy":[67],"is":[70],"due":[71],"part":[73],"relative":[75],"differences":[76],"proliferation":[79],"success":[81],"of":[82,125,130,147,198,203,226,240,243,253,305,309],"TEs":[83,126,205],"across":[84,217,257],"anuran":[85,113,119,131,148,255],"genomes.":[86],"this":[88,241],"study,":[89],"we":[90,108,136,166,261],"ask:":[91],"do":[92],"specific":[93,310],"TE":[94,142,157,244,266,311],"families":[95,206,267,312],"drive":[96],"these":[102],"patterns":[103],"phylogenetically-constrained?":[104],"To":[105],"answer":[106],"this,":[107],"use":[109],"61":[110],"publicly":[111],"available":[112],"reference":[114],"assemblies,":[116],"comprising":[117],"22":[118],"families,":[120],"investigate":[122],"effects":[124],"on":[127,250,285],"evolution":[129],"size.":[133],"addition,":[135],"used":[137],"repeat":[138],"landscapes":[139],"analyze":[141],"activity":[143,158,308],"context":[146],"evolutionary":[149,258],"history,":[150],"order":[152],"understand":[154],"how":[155,168],"lineage-specific":[156],"affects":[159],"anurans.":[164,218],"Finally,":[165,260],"examined":[167],"life":[169],"history":[170],"traits":[171],"that":[172,195,222,238,277],"have":[173,245],"been":[174],"predicted":[175],"be":[177,281],"constrained":[178],"by":[179],"size,":[181,186,236],"larval":[182,274],"period":[183],"clutch":[185],"associated":[188,212],"TEs.":[190,297],"RESULTS:":[191],"Our":[192,299],"results":[193],"suggest":[194],"copy":[196,224],"number":[197],"total":[201],"content":[202],"several":[204,265],"(L1/CIN4,":[207,313],"Ty1/Copia,":[208,314],"Ty3/DIRS1,":[209,315],"hobo-Activator)":[210,316],"increased":[214,234],"We":[219],"further":[220],"found":[221,262],"numbers":[225],"recently":[227],"active":[228],"Ty3":[229],"retrotransposons":[230],"correlated":[232],"suggesting":[237],"expansions":[239],"family":[242],"had":[246],"a":[247,282],"distinct":[248],"effect":[249],"time.":[259],"interactions":[263],"between":[264],"(hobo-Activator,":[268],"PiggyBac,":[269],"L2/CR1/Rex,":[270],"SINEs)":[272],"period,":[275],"indicating":[276],"developmental":[278,318],"time":[279],"may":[280,293],"major":[283],"constraint":[284],"species":[289],"additional":[291],"constraints":[292,319],"more":[294],"effectively":[295],"purge":[296],"CONCLUSION:":[298],"findings":[300],"underscore":[301],"pivotal":[303],"roles":[304],"both":[306],"amphibian":[321],"evolution.":[324]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2025-12-18T00:00:00"}