{"id":"https://openalex.org/W4417417618","doi":"https://doi.org/10.1038/s41467-025-67303-5","title":"PhaseT3M: 3D imaging at 1.6 \u212b resolution via electron cryo-tomography with nonlinear phase retrieval","display_name":"PhaseT3M: 3D imaging at 1.6 \u212b resolution via electron cryo-tomography with nonlinear phase retrieval","publication_year":2025,"publication_date":"2025-12-17","ids":{"openalex":"https://openalex.org/W4417417618","doi":"https://doi.org/10.1038/s41467-025-67303-5","pmid":"https://pubmed.ncbi.nlm.nih.gov/41407680"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-025-67303-5","doi":"https://doi.org/10.1038/s41467-025-67303-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-025-67303-5","pdf_url":"https://www.nature.com/articles/s41467-025-67303-5_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["arxiv","crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-025-67303-5_reference.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050066529","display_name":"Juhyeok Lee","orcid":"https://orcid.org/0000-0002-4866-5728","observed_orcids":["https://orcid.org/0000-0002-4866-5728"]},"institutions":[{"id":"https://openalex.org/I148283060","display_name":"Lawrence Berkeley National Laboratory","ror":"https://ror.org/02jbv0t02","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I148283060","https://openalex.org/I39565521"]},{"id":"https://openalex.org/I4387154492","display_name":"Molecular Foundry","ror":"https://ror.org/01fdhpk75","country_code":null,"type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I148283060","https://openalex.org/I39565521","https://openalex.org/I4387154492"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Juhyeok Lee","raw_affiliation_strings":["Energy Geosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. jhlee0667@lbl.gov","National Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. jhlee0667@lbl.gov"],"raw_orcid":"https://orcid.org/0000-0002-4866-5728","affiliations":[{"raw_affiliation_string":"Energy Geosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. jhlee0667@lbl.gov","institution_ids":["https://openalex.org/I148283060"]},{"raw_affiliation_string":"National Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. jhlee0667@lbl.gov","institution_ids":["https://openalex.org/I148283060","https://openalex.org/I4387154492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110061783","display_name":"Samuel Moon-Ho Song","orcid":"https://orcid.org/0009-0007-2493-1861","observed_orcids":["https://orcid.org/0009-0007-2493-1861"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel W. Song","raw_affiliation_strings":["Department of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA"],"raw_orcid":"https://orcid.org/0009-0007-2493-1861","affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024862919","display_name":"Min Gee Cho","orcid":"https://orcid.org/0000-0003-4490-7352","observed_orcids":["https://orcid.org/0000-0003-4490-7352"]},"institutions":[{"id":"https://openalex.org/I148283060","display_name":"Lawrence Berkeley National Laboratory","ror":"https://ror.org/02jbv0t02","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I148283060","https://openalex.org/I39565521"]},{"id":"https://openalex.org/I4387154492","display_name":"Molecular Foundry","ror":"https://ror.org/01fdhpk75","country_code":null,"type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I148283060","https://openalex.org/I39565521","https://openalex.org/I4387154492"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Min Gee Cho","raw_affiliation_strings":["National Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, USA","institution_ids":["https://openalex.org/I148283060","https://openalex.org/I4387154492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043991968","display_name":"Georgios Varnavides","orcid":"https://orcid.org/0000-0001-8338-3323","observed_orcids":["https://orcid.org/0000-0001-8338-3323"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Georgios Varnavides","raw_affiliation_strings":["Department of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA","Miller Institute for Basic Research in Science, University of California Berkeley, Berkeley, CA, USA"],"raw_orcid":"https://orcid.org/0000-0001-8338-3323","affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Miller Institute for Basic Research in Science, University of California Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006463823","display_name":"Stephanie M. Ribet","orcid":"https://orcid.org/0000-0002-7117-066X","observed_orcids":["https://orcid.org/0000-0002-7117-066X"]},"institutions":[{"id":"https://openalex.org/I148283060","display_name":"Lawrence Berkeley National Laboratory","ror":"https://ror.org/02jbv0t02","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I148283060","https://openalex.org/I39565521"]},{"id":"https://openalex.org/I4387154492","display_name":"Molecular Foundry","ror":"https://ror.org/01fdhpk75","country_code":null,"type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I148283060","https://openalex.org/I39565521","https://openalex.org/I4387154492"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephanie M. Ribet","raw_affiliation_strings":["National Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-7117-066X","affiliations":[{"raw_affiliation_string":"National Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, USA","institution_ids":["https://openalex.org/I148283060","https://openalex.org/I4387154492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006948939","display_name":"Colin Ophus","orcid":"https://orcid.org/0000-0003-2348-8558","observed_orcids":["https://orcid.org/0000-0003-2348-8558"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Colin Ophus","raw_affiliation_strings":["Department of Materials Science and Engineering, Stanford University, Stanford, CA, USA"],"raw_orcid":"https://orcid.org/0000-0003-2348-8558","affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, Stanford University, Stanford, CA, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012826031","display_name":"Mary Cooper Scott","orcid":"https://orcid.org/0000-0002-9543-6725","observed_orcids":["https://orcid.org/0000-0002-9543-6725"]},"institutions":[{"id":"https://openalex.org/I148283060","display_name":"Lawrence Berkeley National Laboratory","ror":"https://ror.org/02jbv0t02","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I148283060","https://openalex.org/I39565521"]},{"id":"https://openalex.org/I4387154492","display_name":"Molecular Foundry","ror":"https://ror.org/01fdhpk75","country_code":null,"type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I148283060","https://openalex.org/I39565521","https://openalex.org/I4387154492"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mary C. Scott","raw_affiliation_strings":["Department of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA. mary.scott@berkeley.edu","National Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. mary.scott@berkeley.edu"],"raw_orcid":"https://orcid.org/0000-0002-9543-6725","affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA. mary.scott@berkeley.edu","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"National Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. mary.scott@berkeley.edu","institution_ids":["https://openalex.org/I148283060","https://openalex.org/I4387154492"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079069132","display_name":"Michael Whittaker","orcid":"https://orcid.org/0000-0002-9724-3409","observed_orcids":["https://orcid.org/0000-0002-9724-3409"]},"institutions":[{"id":"https://openalex.org/I148283060","display_name":"Lawrence Berkeley National Laboratory","ror":"https://ror.org/02jbv0t02","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I148283060","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael L. Whittaker","raw_affiliation_strings":["Energy Geosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. mwhittaker@lbl.gov","Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. mwhittaker@lbl.gov"],"raw_orcid":"https://orcid.org/0000-0002-9724-3409","affiliations":[{"raw_affiliation_string":"Energy Geosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. mwhittaker@lbl.gov","institution_ids":["https://openalex.org/I148283060"]},{"raw_affiliation_string":"Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. mwhittaker@lbl.gov","institution_ids":["https://openalex.org/I148283060"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5012826031","https://openalex.org/A5050066529","https://openalex.org/A5079069132"],"corresponding_institution_ids":["https://openalex.org/I148283060","https://openalex.org/I4387154492","https://openalex.org/I95457486"],"apc_list":{"value":6990,"currency":"USD","value_usd":6990},"apc_paid":{"value":6990,"currency":"USD","value_usd":6990},"fwci":1.0413,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.76712329,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"17","issue":"1","first_page":"690","last_page":"690"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13552","display_name":"Advanced Materials Characterization Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11183","display_name":"Advanced X-ray Imaging Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cryo-electron-tomography","display_name":"cryo-electron tomography","score":0.972000002861023},{"id":"https://openalex.org/keywords/multiple-scattering","display_name":"multiple scattering","score":0.6940000057220459},{"id":"https://openalex.org/keywords/aberration-correction","display_name":"aberration correction","score":0.8859999775886536},{"id":"https://openalex.org/keywords/missing-wedge","display_name":"missing wedge","score":0.8479999899864197},{"id":"https://openalex.org/keywords/positivity-constraints","display_name":"positivity constraints","score":0.8059999942779541},{"id":"https://openalex.org/keywords/high-resolution-3d-imaging","display_name":"high-resolution 3D imaging","score":0.7080000042915344},{"id":"https://openalex.org/keywords/radiation-damage","display_name":"radiation damage","score":0.4650000035762787},{"id":"https://openalex.org/keywords/phase-contrast","display_name":"phase contrast","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C81793267","wikidata":"https://www.wikidata.org/wiki/Q7180962","display_name":"Phase retrieval","level":3,"score":0.6187000274658203},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.5986999869346619},{"id":"https://openalex.org/C191486275","wikidata":"https://www.wikidata.org/wiki/Q210028","display_name":"Scattering","level":2,"score":0.5274999737739563},{"id":"https://openalex.org/C147120987","wikidata":"https://www.wikidata.org/wiki/Q2225","display_name":"Electron","level":2,"score":0.5065000057220459},{"id":"https://openalex.org/C158622935","wikidata":"https://www.wikidata.org/wiki/Q660848","display_name":"Nonlinear system","level":2,"score":0.5047000050544739},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.4823000133037567},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.4580000042915344},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.45579999685287476},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.4498000144958496},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4124000072479248},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.40619999170303345},{"id":"https://openalex.org/C55020928","wikidata":"https://www.wikidata.org/wiki/Q3813865","display_name":"Image quality","level":3,"score":0.40529999136924744},{"id":"https://openalex.org/C32022120","wikidata":"https://www.wikidata.org/wiki/Q797225","display_name":"Interference (communication)","level":3,"score":0.3806999921798706},{"id":"https://openalex.org/C2776036281","wikidata":"https://www.wikidata.org/wiki/Q48769818","display_name":"Constraint (computer-aided design)","level":2,"score":0.3605000078678131},{"id":"https://openalex.org/C2779619515","wikidata":"https://www.wikidata.org/wiki/Q6935089","display_name":"Multislice","level":2,"score":0.35359999537467957},{"id":"https://openalex.org/C64389972","wikidata":"https://www.wikidata.org/wiki/Q2075980","display_name":"Biological specimen","level":2,"score":0.3384000062942505},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.31869998574256897},{"id":"https://openalex.org/C2779885931","wikidata":"https://www.wikidata.org/wiki/Q17010029","display_name":"Microwave imaging","level":3,"score":0.31779998540878296},{"id":"https://openalex.org/C146285849","wikidata":"https://www.wikidata.org/wiki/Q1327107","display_name":"Electron scattering","level":3,"score":0.31049999594688416},{"id":"https://openalex.org/C75806775","wikidata":"https://www.wikidata.org/wiki/Q5358194","display_name":"Electron tomography","level":4,"score":0.30379998683929443},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.2994999885559082},{"id":"https://openalex.org/C58640550","wikidata":"https://www.wikidata.org/wiki/Q7180908","display_name":"Phase-contrast imaging","level":3,"score":0.29840001463890076},{"id":"https://openalex.org/C135252773","wikidata":"https://www.wikidata.org/wiki/Q1567213","display_name":"Inverse problem","level":2,"score":0.2815000116825104},{"id":"https://openalex.org/C20702342","wikidata":"https://www.wikidata.org/wiki/Q5190506","display_name":"Cryo-electron microscopy","level":2,"score":0.26809999346733093},{"id":"https://openalex.org/C160234255","wikidata":"https://www.wikidata.org/wiki/Q812535","display_name":"Bayesian inference","level":3,"score":0.2651999890804291},{"id":"https://openalex.org/C2778517922","wikidata":"https://www.wikidata.org/wiki/Q7140482","display_name":"Particle (ecology)","level":2,"score":0.2635999917984009},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.25920000672340393},{"id":"https://openalex.org/C151193507","wikidata":"https://www.wikidata.org/wiki/Q898815","display_name":"Phase contrast microscopy","level":2,"score":0.25920000672340393},{"id":"https://openalex.org/C174558057","wikidata":"https://www.wikidata.org/wiki/Q11639409","display_name":"Inverse scattering problem","level":3,"score":0.25450000166893005}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1038/s41467-025-67303-5","doi":"https://doi.org/10.1038/s41467-025-67303-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-025-67303-5","pdf_url":"https://www.nature.com/articles/s41467-025-67303-5_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-6531498/v1","doi":"https://doi.org/10.21203/rs.3.rs-6531498/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-6531498/v1","pdf_url":"https://www.researchsquare.com/article/rs-6531498/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmid:41407680","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41407680","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature communications","raw_type":"Journal Article"},{"id":"pmh:oai:arXiv.org:2504.16332","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/2504.16332","pdf_url":"https://arxiv.org/pdf/2504.16332","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:doaj.org/article:39ca839cd9f948579c2abb8c4120a693","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/39ca839cd9f948579c2abb8c4120a693","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, Vol 17, Iss 1, Pp 1-14 (2025)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12820068","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12820068/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nat Commun","raw_type":"Text"},{"id":"doi:10.48550/arxiv.2504.16332","doi":"https://doi.org/10.48550/arxiv.2504.16332","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2504.16332","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"Preprint"}],"best_oa_location":{"id":"doi:10.1038/s41467-025-67303-5","doi":"https://doi.org/10.1038/s41467-025-67303-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-025-67303-5","pdf_url":"https://www.nature.com/articles/s41467-025-67303-5_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1286236842","display_name":null,"funder_award_id":"-AC02-05CH11231","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G1286251239","display_name":null,"funder_award_id":"DE-AC02","funder_id":"https://openalex.org/F4320337480","funder_display_name":"Basic Energy Sciences"},{"id":"https://openalex.org/G30714459","display_name":null,"funder_award_id":"DE-AC02-05CH11231.","funder_id":"https://openalex.org/F4320337480","funder_display_name":"Basic Energy Sciences"},{"id":"https://openalex.org/G419881185","display_name":null,"funder_award_id":"DEAC02\u201305CH11231","funder_id":"https://openalex.org/F4320332359","funder_display_name":"Office of Science"},{"id":"https://openalex.org/G42916606","display_name":null,"funder_award_id":"DE AC02 05CH11231","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G498139845","display_name":null,"funder_award_id":"DE-AC02","funder_id":"https://openalex.org/F4320332359","funder_display_name":"Office of Science"},{"id":"https://openalex.org/G650090426","display_name":null,"funder_award_id":"AC02\u201305CH11231","funder_id":"https://openalex.org/F4320337480","funder_display_name":"Basic Energy Sciences"},{"id":"https://openalex.org/G6852334964","display_name":"Graduate Research Fellowship Program (GRFP)","funder_award_id":"2146752","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8751405378","display_name":null,"funder_award_id":"DGE 2146 752","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G969889393","display_name":null,"funder_award_id":"DE-AC02-","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320312984","display_name":"California Institute for Quantitative Biosciences","ror":"https://ror.org/04n1n3n22"},{"id":"https://openalex.org/F4320317220","display_name":"National Energy Research Scientific Computing Center","ror":"https://ror.org/05v3mvq14"},{"id":"https://openalex.org/F4320332359","display_name":"Office of Science","ror":"https://ror.org/00mmn6b08"},{"id":"https://openalex.org/F4320337480","display_name":"Basic Energy Sciences","ror":"https://ror.org/05mg91w61"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4417417618.pdf","grobid_xml":"https://content.openalex.org/works/W4417417618.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W1812643764","https://openalex.org/W1966272533","https://openalex.org/W1967857752","https://openalex.org/W1990919278","https://openalex.org/W1997009546","https://openalex.org/W1997581342","https://openalex.org/W2006221457","https://openalex.org/W2007855820","https://openalex.org/W2013105557","https://openalex.org/W2023990870","https://openalex.org/W2025007543","https://openalex.org/W2028160465","https://openalex.org/W2029101220","https://openalex.org/W2039175603","https://openalex.org/W2039714018","https://openalex.org/W2047965006","https://openalex.org/W2051925784","https://openalex.org/W2056370875","https://openalex.org/W2067248552","https://openalex.org/W2069845974","https://openalex.org/W2101208957","https://openalex.org/W2128934324","https://openalex.org/W2129906827","https://openalex.org/W2146583368","https://openalex.org/W2147388225","https://openalex.org/W2148317024","https://openalex.org/W2149360962","https://openalex.org/W2167099394","https://openalex.org/W2323536686","https://openalex.org/W2327434159","https://openalex.org/W2332981273","https://openalex.org/W2466725324","https://openalex.org/W2475353867","https://openalex.org/W2486933018","https://openalex.org/W2487704570","https://openalex.org/W2593511418","https://openalex.org/W2805746983","https://openalex.org/W2953320394","https://openalex.org/W2980491118","https://openalex.org/W3015097303","https://openalex.org/W3015321620","https://openalex.org/W3046477201","https://openalex.org/W3089400930","https://openalex.org/W3093589504","https://openalex.org/W3093646295","https://openalex.org/W3094051077","https://openalex.org/W3095893897","https://openalex.org/W3201725235","https://openalex.org/W4200311841","https://openalex.org/W4233760620","https://openalex.org/W4242391437","https://openalex.org/W4282566975","https://openalex.org/W4377020178","https://openalex.org/W4387965243","https://openalex.org/W4403565462","https://openalex.org/W4404944846"],"related_works":[],"abstract_inverted_index":{"Abstract":[0],"Electron":[1],"cryo-tomography":[2],"(cryo-ET)":[3],"enables":[4],"3D":[5,149],"imaging":[6,150],"of":[7,20,96,151],"complex,":[8,152],"radiation-sensitive":[9,153],"structures":[10],"with":[11,25,123],"molecular":[12],"detail.":[13],"However,":[14],"image":[15],"contrast":[16],"from":[17],"the":[18],"interference":[19],"scattered":[21],"electrons":[22],"is":[23,53],"nonlinear":[24],"atomic":[26],"density":[27],"and":[28,64,114,119,140],"multiple":[29,112],"scattering":[30,113],"further":[31],"complicates":[32],"interpretation.":[33],"These":[34],"effects":[35],"degrade":[36],"resolution,":[37],"particularly":[38],"in":[39,61],"conventional":[40,100],"reconstruction":[41],"algorithms,":[42],"which":[43],"assume":[44],"linearity.":[45],"Particle":[46],"averaging":[47],"can":[48],"reduce":[49],"such":[50],"issues":[51],"but":[52],"unsuitable":[54],"for":[55,111,117,147],"heterogeneous":[56],"or":[57],"dynamic":[58],"samples":[59],"ubiquitous":[60],"biology,":[62],"chemistry,":[63],"materials":[65],"sciences.":[66],"Here,":[67],"we":[68],"develop":[69],"a":[70,82,93,108,124,144],"phase":[71],"retrieval-based":[72],"cryo-ET":[73],"method,":[74],"PhaseT\u2203M.":[75],"We":[76],"experimentally":[77],"demonstrate":[78],"its":[79],"application":[80],"to":[81,127,134],"~7":[83],"nm":[84,89],"Co3O4":[85],"nanoparticle":[86],"on":[87],"~30":[88],"carbon":[90],"substrate,":[91],"achieving":[92],"maximum":[94],"resolution":[95,139],"1.6":[97],"\u00c5,":[98],"surpassing":[99],"limits":[101],"using":[102],"standard":[103,146],"cryo-TEM":[104],"equipment.":[105],"PhaseT\u2203M":[106],"uses":[107],"multislice":[109],"model":[110],"Bayesian":[115],"optimization":[116],"alignment":[118],"computational":[120],"aberration":[121],"correction,":[122],"positivity":[125],"constraint":[126],"recover":[128],"'missing":[129],"wedge'":[130],"information.":[131],"Applied":[132],"directly":[133],"biological":[135],"particles,":[136],"it":[137],"enhances":[138],"reduces":[141],"artifacts,":[142],"establishing":[143],"new":[145],"routine":[148],"materials.":[154]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2025-12-17T00:00:00"}