{"id":"https://openalex.org/W4417213848","doi":"https://doi.org/10.1002/nbm.70344","title":"Restriction\u2010Weighted Q\u2010Space Trajectory Imaging (ResQ): Toward Mapping Diffusion\u2010Time Effects With Tensor\u2010Valued Diffusion Encoding in Human Prostate Cancer Xenografts","display_name":"Restriction\u2010Weighted Q\u2010Space Trajectory Imaging (ResQ): Toward Mapping Diffusion\u2010Time Effects With Tensor\u2010Valued Diffusion Encoding in Human Prostate Cancer Xenografts","publication_year":2026,"publication_date":"2026-06-28","ids":{"openalex":"https://openalex.org/W4417213848","doi":"https://doi.org/10.1002/nbm.70344","pmid":"https://pubmed.ncbi.nlm.nih.gov/42366513","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13311205"},"language":"en","primary_location":{"id":"doi:10.1002/nbm.70344","doi":"https://doi.org/10.1002/nbm.70344","is_oa":true,"landing_page_url":"https://doi.org/10.1002/nbm.70344","pdf_url":null,"source":{"id":"https://openalex.org/S45012897","display_name":"NMR in Biomedicine","issn_l":"0952-3480","issn":["0952-3480","1099-1492"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NMR in Biomedicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1002/nbm.70344","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064097093","display_name":"Filip Szczepankiewicz","orcid":"https://orcid.org/0000-0002-5251-587X","observed_orcids":["https://orcid.org/0000-0002-5251-587X"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Filip Szczepankiewicz","raw_affiliation_strings":["Department of Medical Radiation Physics Lund University  Lund Sweden","Lund University"],"raw_orcid":"https://orcid.org/0000-0002-5251-587X","affiliations":[{"raw_affiliation_string":"Department of Medical Radiation Physics Lund University  Lund Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009263881","display_name":"Malwina Molendowska","orcid":"https://orcid.org/0000-0001-8540-8424","observed_orcids":["https://orcid.org/0000-0001-8540-8424"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Malwina Molendowska","raw_affiliation_strings":["Department of Medical Radiation Physics Lund University  Lund Sweden","Lund University"],"raw_orcid":"https://orcid.org/0000-0001-8540-8424","affiliations":[{"raw_affiliation_string":"Department of Medical Radiation Physics Lund University  Lund Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048070628","display_name":"Samo Lasi\u010d","orcid":"https://orcid.org/0000-0002-9284-7182","observed_orcids":["https://orcid.org/0000-0002-9284-7182"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Samo Lasi\u010d","raw_affiliation_strings":["Department of Diagnostic Radiology Lund University  Lund Sweden","Lund University"],"raw_orcid":"https://orcid.org/0000-0002-9284-7182","affiliations":[{"raw_affiliation_string":"Department of Diagnostic Radiology Lund University  Lund Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083101099","display_name":"Marcella Safi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Marcella E. Safi","raw_affiliation_strings":["Department of Clinical Sciences Lund Lund University  Lund Sweden","Lund University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences Lund Lund University  Lund Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056164511","display_name":"Michael E. Gottschalk","orcid":"https://orcid.org/0000-0002-3688-240X","observed_orcids":["https://orcid.org/0000-0002-3688-240X"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Michael Gottschalk","raw_affiliation_strings":["Lund University Bioimaging Centre Lund University  Lund Sweden","Lund University Bioimaging Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lund University Bioimaging Centre Lund University  Lund Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Bioimaging Center","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033637880","display_name":"Evangelia Sereti","orcid":"https://orcid.org/0000-0002-5947-9971","observed_orcids":["https://orcid.org/0000-0002-5947-9971"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Evangelia Sereti","raw_affiliation_strings":["Department of Translational Medicine Lund University  Malm\u00f6 Sweden","Lund University"],"raw_orcid":"https://orcid.org/0000-0002-5947-9971","affiliations":[{"raw_affiliation_string":"Department of Translational Medicine Lund University  Malm\u00f6 Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015634061","display_name":"Anders S Bjartell","orcid":"https://orcid.org/0000-0002-5761-3786","observed_orcids":["https://orcid.org/0000-0002-5761-3786"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Anders Bjartell","raw_affiliation_strings":["Department of Translational Medicine Lund University  Malm\u00f6 Sweden","Department of Urology Sk\u00e5ne University Hospital  Malm\u00f6 Sweden","Lund University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Translational Medicine Lund University  Malm\u00f6 Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Department of Urology Sk\u00e5ne University Hospital  Malm\u00f6 Sweden","institution_ids":["https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Lund University","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002886384","display_name":"Linda Knutsson","orcid":"https://orcid.org/0000-0002-4263-113X","observed_orcids":["https://orcid.org/0000-0002-4263-113X"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Linda Knutsson","raw_affiliation_strings":["Department of Medical Radiation Physics Lund University  Lund Sweden","Lund University"],"raw_orcid":"https://orcid.org/0000-0002-4263-113X","affiliations":[{"raw_affiliation_string":"Department of Medical Radiation Physics Lund University  Lund Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070074713","display_name":"Oskar Vilhelmsson Timmermand","orcid":"https://orcid.org/0000-0002-4187-1588","observed_orcids":["https://orcid.org/0000-0002-4187-1588"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Oskar Vilhelmsson Timmermand","raw_affiliation_strings":["Department of Clinical Sciences Lund Lund University  Lund Sweden","Lund University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences Lund Lund University  Lund Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059959971","display_name":"Crister P Ceberg","orcid":"https://orcid.org/0000-0003-1255-0336","observed_orcids":["https://orcid.org/0000-0003-1255-0336"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Crister Ceberg","raw_affiliation_strings":["Department of Medical Radiation Physics Lund University  Lund Sweden","Lund University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Radiation Physics Lund University  Lund Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109264777","display_name":"Joanna Strand","orcid":"https://orcid.org/0009-0004-0616-3668","observed_orcids":["https://orcid.org/0009-0004-0616-3668"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Joanna Strand","raw_affiliation_strings":["Department of Clinical Sciences Lund Lund University  Lund Sweden","Department of Clinical Sciences Lund, Oncology Lund University  Lund Sweden","Department of Hematology, Oncology, Radiation Physics, Sk\u00e5ne University Hospital Lund University  Lund Sweden","Lund University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences Lund Lund University  Lund Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Department of Clinical Sciences Lund, Oncology Lund University  Lund Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Department of Hematology, Oncology, Radiation Physics, Sk\u00e5ne University Hospital Lund University  Lund Sweden","institution_ids":["https://openalex.org/I187531555","https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Lund University","institution_ids":["https://openalex.org/I187531555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5064097093"],"corresponding_institution_ids":["https://openalex.org/I187531555"],"apc_list":{"value":3640,"currency":"USD","value_usd":3640},"apc_paid":{"value":3640,"currency":"USD","value_usd":3640},"fwci":13.9461,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.98156764,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"39","issue":"8","first_page":"e70344","last_page":"e70344"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.009700000286102295,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diffusion-time-dependence","display_name":"diffusion time dependence","score":0.9340000152587891},{"id":"https://openalex.org/keywords/prostate-cancer-xenografts","display_name":"prostate cancer xenografts","score":0.8560000061988831},{"id":"https://openalex.org/keywords/lncap-cells","display_name":"LNCaP cells","score":0.7260000109672546},{"id":"https://openalex.org/keywords/external-beam-radiotherapy","display_name":"external beam radiotherapy","score":0.7210000157356262},{"id":"https://openalex.org/keywords/diffusion-mri","display_name":"diffusion MRI","score":0.625},{"id":"https://openalex.org/keywords/mean-diffusivity","display_name":"mean diffusivity","score":0.9570000171661377},{"id":"https://openalex.org/keywords/gradient-waveform-design","display_name":"gradient waveform design","score":0.8949999809265137},{"id":"https://openalex.org/keywords/imaging-biomarkers","display_name":"imaging biomarkers","score":0.7149999737739563}],"concepts":[{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.6194999814033508},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.6007000207901001},{"id":"https://openalex.org/C197424946","wikidata":"https://www.wikidata.org/wiki/Q1165717","display_name":"Waveform","level":3,"score":0.5763999819755554},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.5504000186920166},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.4993000030517578},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.46320000290870667},{"id":"https://openalex.org/C37668627","wikidata":"https://www.wikidata.org/wiki/Q3381809","display_name":"Thermal diffusivity","level":2,"score":0.44440001249313354},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.42329999804496765},{"id":"https://openalex.org/C13662910","wikidata":"https://www.wikidata.org/wiki/Q193139","display_name":"Trajectory","level":2,"score":0.413100004196167},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3804999887943268},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.37119999527931213},{"id":"https://openalex.org/C85725439","wikidata":"https://www.wikidata.org/wiki/Q466686","display_name":"Anisotropy","level":2,"score":0.3538999855518341},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3490000069141388},{"id":"https://openalex.org/C125411270","wikidata":"https://www.wikidata.org/wiki/Q18653","display_name":"Encoding (memory)","level":2,"score":0.3343999981880188},{"id":"https://openalex.org/C2775936607","wikidata":"https://www.wikidata.org/wiki/Q466845","display_name":"Tracking (education)","level":2,"score":0.3330000042915344},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.31700000166893005},{"id":"https://openalex.org/C184050105","wikidata":"https://www.wikidata.org/wiki/Q273163","display_name":"Isotropy","level":2,"score":0.3089999854564667},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.30709999799728394},{"id":"https://openalex.org/C2780167933","wikidata":"https://www.wikidata.org/wiki/Q1550652","display_name":"Pulse (music)","level":3,"score":0.3003999888896942},{"id":"https://openalex.org/C70816921","wikidata":"https://www.wikidata.org/wiki/Q258852","display_name":"Effective diffusion coefficient","level":3,"score":0.29089999198913574},{"id":"https://openalex.org/C27753989","wikidata":"https://www.wikidata.org/wiki/Q284885","display_name":"Superposition principle","level":2,"score":0.289000004529953},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.2842000126838684},{"id":"https://openalex.org/C183115368","wikidata":"https://www.wikidata.org/wiki/Q856577","display_name":"Weighting","level":2,"score":0.2824999988079071},{"id":"https://openalex.org/C203504353","wikidata":"https://www.wikidata.org/wiki/Q4765461","display_name":"Anisotropic diffusion","level":3,"score":0.28189998865127563},{"id":"https://openalex.org/C2992283565","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion imaging","level":4,"score":0.27709999680519104},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.27410000562667847},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.2685000002384186},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.2667999863624573},{"id":"https://openalex.org/C198082294","wikidata":"https://www.wikidata.org/wiki/Q3399648","display_name":"Position (finance)","level":2,"score":0.26109999418258667},{"id":"https://openalex.org/C30475298","wikidata":"https://www.wikidata.org/wiki/Q909554","display_name":"Computational physics","level":1,"score":0.25029999017715454}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016880","descriptor_name":"Anisotropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038524","descriptor_name":"Diffusion Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064593","descriptor_name":"Heterografts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/nbm.70344","doi":"https://doi.org/10.1002/nbm.70344","is_oa":true,"landing_page_url":"https://doi.org/10.1002/nbm.70344","pdf_url":null,"source":{"id":"https://openalex.org/S45012897","display_name":"NMR in Biomedicine","issn_l":"0952-3480","issn":["0952-3480","1099-1492"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NMR in Biomedicine","raw_type":"journal-article"},{"id":"doi:10.64898/2025.12.08.692924","doi":"https://doi.org/10.64898/2025.12.08.692924","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2025.12.08.692924","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:42366513","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42366513","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NMR in biomedicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13311205","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13311205/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NMR Biomed","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1002/nbm.70344","doi":"https://doi.org/10.1002/nbm.70344","is_oa":true,"landing_page_url":"https://doi.org/10.1002/nbm.70344","pdf_url":null,"source":{"id":"https://openalex.org/S45012897","display_name":"NMR in Biomedicine","issn_l":"0952-3480","issn":["0952-3480","1099-1492"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NMR in Biomedicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8999999761581421,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1552360817","display_name":null,"funder_award_id":"22 2011 Pj","funder_id":"https://openalex.org/F4320321491","funder_display_name":"Cancerfonden"},{"id":"https://openalex.org/G2341293354","display_name":"MRI f\u00f6r icke-invasiv detektion och diagnosticering av prostatacancer","funder_award_id":"2021-04844","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G3453229702","display_name":null,"funder_award_id":"FBKS\u20102024\u201023\u2010(608)","funder_id":"https://openalex.org/F4320322790","funder_display_name":"Fru Berta Kamprads Stiftelse"},{"id":"https://openalex.org/G3616616750","display_name":null,"funder_award_id":"220592JIA","funder_id":"https://openalex.org/F4320321491","funder_display_name":"Cancerfonden"},{"id":"https://openalex.org/G3735550507","display_name":null,"funder_award_id":"FBKS\u20102022\u201041\u2010(425)","funder_id":"https://openalex.org/F4320322790","funder_display_name":"Fru Berta Kamprads Stiftelse"},{"id":"https://openalex.org/G5349841095","display_name":null,"funder_award_id":"FBKS\u20102021\u201024\u2010(344)","funder_id":"https://openalex.org/F4320322790","funder_display_name":"Fru Berta Kamprads Stiftelse"},{"id":"https://openalex.org/G7537964712","display_name":null,"funder_award_id":"22 0533 FE","funder_id":"https://openalex.org/F4320321491","funder_display_name":"Cancerfonden"}],"funders":[{"id":"https://openalex.org/F4320316287","display_name":"Stiftelsen Thelma Zo\u00e9gas fond f\u00f6r medicinsk forskning","ror":"https://ror.org/0024dsk80"},{"id":"https://openalex.org/F4320321491","display_name":"Cancerfonden","ror":"https://ror.org/0527jb766"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320322790","display_name":"Fru Berta Kamprads Stiftelse","ror":"https://ror.org/04wv8j283"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":100,"referenced_works":["https://openalex.org/W131907178","https://openalex.org/W1548679134","https://openalex.org/W1561966395","https://openalex.org/W1568793698","https://openalex.org/W1821725364","https://openalex.org/W1827911007","https://openalex.org/W1829170282","https://openalex.org/W1923881155","https://openalex.org/W1952748271","https://openalex.org/W1968735591","https://openalex.org/W1970989579","https://openalex.org/W1994734080","https://openalex.org/W2005591080","https://openalex.org/W2009651170","https://openalex.org/W2013932017","https://openalex.org/W2024739052","https://openalex.org/W2025487267","https://openalex.org/W2027803689","https://openalex.org/W2040537366","https://openalex.org/W2041626473","https://openalex.org/W2057334693","https://openalex.org/W2069029133","https://openalex.org/W2070546949","https://openalex.org/W2084761689","https://openalex.org/W2110839901","https://openalex.org/W2133287637","https://openalex.org/W2147133578","https://openalex.org/W2149092213","https://openalex.org/W2152765865","https://openalex.org/W2157404197","https://openalex.org/W2275837766","https://openalex.org/W2486427691","https://openalex.org/W2487652384","https://openalex.org/W2502329627","https://openalex.org/W2509202063","https://openalex.org/W2561760877","https://openalex.org/W2586947504","https://openalex.org/W2598956420","https://openalex.org/W2621707408","https://openalex.org/W2755595323","https://openalex.org/W2757827026","https://openalex.org/W2767431474","https://openalex.org/W2786701104","https://openalex.org/W2795668232","https://openalex.org/W2806665283","https://openalex.org/W2811455089","https://openalex.org/W2903577385","https://openalex.org/W2904374699","https://openalex.org/W2915399290","https://openalex.org/W2928868161","https://openalex.org/W2930043270","https://openalex.org/W2950990733","https://openalex.org/W2953575207","https://openalex.org/W2963655134","https://openalex.org/W2999049145","https://openalex.org/W3004510674","https://openalex.org/W3010073879","https://openalex.org/W3010331388","https://openalex.org/W3033259844","https://openalex.org/W3035039202","https://openalex.org/W3042258507","https://openalex.org/W3042754124","https://openalex.org/W3043321626","https://openalex.org/W3048150683","https://openalex.org/W3143013739","https://openalex.org/W3154506599","https://openalex.org/W3164427193","https://openalex.org/W3164646106","https://openalex.org/W3200840358","https://openalex.org/W4200116910","https://openalex.org/W4200390590","https://openalex.org/W4200567151","https://openalex.org/W4205278067","https://openalex.org/W4211245039","https://openalex.org/W4220880399","https://openalex.org/W4221104710","https://openalex.org/W4289522523","https://openalex.org/W4292658370","https://openalex.org/W4294970226","https://openalex.org/W4308731816","https://openalex.org/W4324362414","https://openalex.org/W4328048507","https://openalex.org/W4381470032","https://openalex.org/W4386998509","https://openalex.org/W4387078053","https://openalex.org/W4389178970","https://openalex.org/W4389672576","https://openalex.org/W4390404629","https://openalex.org/W4396812948","https://openalex.org/W4399498529","https://openalex.org/W4399922657","https://openalex.org/W4400975016","https://openalex.org/W4402076571","https://openalex.org/W4403632454","https://openalex.org/W4404599794","https://openalex.org/W4404849805","https://openalex.org/W4405476086","https://openalex.org/W4405883663","https://openalex.org/W4408420705","https://openalex.org/W4410578958"],"related_works":["https://openalex.org/W4414235217","https://openalex.org/W4404744639","https://openalex.org/W4403299754","https://openalex.org/W2726804229","https://openalex.org/W4401573339","https://openalex.org/W1975987828","https://openalex.org/W2275837766","https://openalex.org/W7214318790","https://openalex.org/W7162095932","https://openalex.org/W7161950917"],"abstract_inverted_index":{"ABSTRACT":[0],"Tensor\u2010valued":[1],"diffusion":[2,120,140,251,267,280,300],"encoding":[3,72,301],"employs":[4],"gradient":[5,67],"waveforms":[6,83],"that":[7,39,104,117,286,308],"enable":[8,304],"unique":[9],"sensitivity":[10],"to":[11,102,166,184,240],"microstructural":[12],"features":[13],"of":[14,19,55,81,124,177,249,279,290],"tissue,":[15],"but":[16],"the":[17,44,119,125,175,227,288],"interpretation":[18],"signal":[20,224,228],"and":[21,47,77,100,138,170,207,218,260,276,302,316],"parameters":[22,116,168,186,282],"may":[23,303],"be":[24,262],"confounded":[25],"by":[26,60,110,188],"diffusion\u2010time":[27,41,150,196,235,318],"dependence.":[28,319],"We":[29,63],"introduce":[30],"a":[31,52,65,79,85,246,294],"framework":[32,271],"for":[33,70,298],"restriction\u2010weighted":[34],"q\u2010space":[35,189],"trajectory":[36,190],"imaging":[37,191,306],"(ResQ)":[38],"incorporates":[40],"effects":[42,254,289],"via":[43],"restriction\u2010weighting":[45],"tensor,":[46],"we":[48,181],"evaluate":[49],"it":[50],"in":[51,122,212,237,257],"longitudinal":[53,203],"study":[54],"prostate":[56,96,258],"cancer":[57,97,259],"xenografts":[58],"treated":[59,109,206],"external":[61,111],"radiotherapy.":[62],"proposed":[64],"novel":[66,305],"waveform":[68],"design":[69],"tensor\u2010valued":[71,266,299],"with":[73,94,201,284],"controlled":[74,273],"restriction":[75,179,274],"weighting":[76,275],"applied":[78],"set":[80],"four":[82],"at":[84],"9.4":[86],"T":[87],"preclinical":[88],"MRI":[89,281],"system.":[90],"Mice":[91],"were":[92,105,164],"inoculated":[93],"human":[95],"cells":[98],"(LNCaP)":[99],"assigned":[101],"groups":[103],"untreated":[106,208],"controls":[107],"or":[108],"beam":[112],"irradiation.":[113],"ResQ":[114,183,193,223,270],"produced":[115],"describe":[118],"process":[121],"terms":[123],"mean":[126],"diffusivity":[127],"(":[128,134,142],"D":[129,153,213,216],"),":[130,137],"isotropic":[131,311],"diffusional":[132,312],"variance":[133],"V":[135,143,156,160,219],"Di":[136,157,220],"microscopic":[139,250,314],"anisotropy":[141],"Da":[144,161],")":[145],"as":[146,148],"well":[147],"their":[149,317],"dependence":[151,197,236],"(\u0394":[152],",":[154,158,214,217],"\u0394":[155,159,215],").":[162],"Analyses":[163],"performed":[165],"characterize":[167],"longitudinally":[169],"across":[171,198],"groups.":[172],"To":[173],"highlight":[174],"consequences":[176],"ignoring":[178],"effects,":[180],"compared":[182,283],"analogous":[185],"estimated":[187],"(QTI).":[192],"revealed":[194],"clear":[195],"all":[199],"tumors,":[200],"significant":[202],"differences":[204],"between":[205],"groups,":[209],"most":[210,244],"prominent":[211],".":[221],"The":[222,269],"representation":[225],"captured":[226],"dynamics,":[229],"whereas":[230],"QTI":[231,238],"did":[232],"not.":[233],"Neglecting":[234],"led":[239],"substantial":[241],"parameter":[242],"bias,":[243],"notably":[245],"pronounced":[247],"overestimation":[248],"anisotropy.":[252],"Diffusion\u2010time":[253],"are":[255],"non\u2010negligible":[256],"must":[261],"considered":[263],"when":[264],"using":[265],"encoding.":[268],"enables":[272],"improved":[277],"interpretability":[278],"approaches":[285],"ignore":[287],"restriction.":[291],"This":[292],"provides":[293],"more":[295],"principled":[296],"approach":[297],"biomarkers":[307],"disentangle":[309],"diffusivity,":[310],"variance,":[313],"anisotropy,":[315]},"counts_by_year":[{"year":2026,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-12-11T00:00:00"}