{"id":"https://openalex.org/W4417166286","doi":"https://doi.org/10.7554/elife.109502.1","title":"Characterisation of cold-selective lamina I spinal projection neurons","display_name":"Characterisation of cold-selective lamina I spinal projection neurons","publication_year":2025,"publication_date":"2025-12-09","ids":{"openalex":"https://openalex.org/W4417166286","doi":"https://doi.org/10.7554/elife.109502.1"},"language":"en","primary_location":{"id":"doi:10.7554/elife.109502.1","doi":"https://doi.org/10.7554/elife.109502.1","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.109502.1","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"eLife","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.7554/elife.109502.1","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086677998","display_name":"Aimi Nadia Razlan","orcid":"https://orcid.org/0000-0003-0703-760X","observed_orcids":["https://orcid.org/0000-0003-0703-760X"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Aimi N Razlan","raw_affiliation_strings":["School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073908221","display_name":"Wenhui Ma","orcid":"https://orcid.org/0000-0002-3926-026X","observed_orcids":["https://orcid.org/0000-0002-3926-026X","https://orcid.org/0009-0007-6345-6944","https://orcid.org/0009-0003-5489-4396"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Wenhui Ma","raw_affiliation_strings":["School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009284894","display_name":"Allen C. Dickie","orcid":"https://orcid.org/0000-0002-6339-2801","observed_orcids":["https://orcid.org/0000-0002-6339-2801"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Allen C Dickie","raw_affiliation_strings":["School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038646127","display_name":"Erika Polg\u00e1r","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Erika Polg\u00e1r","raw_affiliation_strings":["School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055945220","display_name":"Anna McFarlane","orcid":"https://orcid.org/0000-0003-1100-8959","observed_orcids":["https://orcid.org/0000-0003-1100-8959"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anna McFarlane","raw_affiliation_strings":["School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113331323","display_name":"Mansi Yadav","orcid":"https://orcid.org/0009-0002-8297-672X","observed_orcids":["https://orcid.org/0009-0002-8297-672X"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mansi Yadav","raw_affiliation_strings":["School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049113432","display_name":"Andrew H. Cooper","orcid":"https://orcid.org/0000-0003-4737-9364","observed_orcids":["https://orcid.org/0000-0003-4737-9364"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew H Cooper","raw_affiliation_strings":["School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow"],"raw_orcid":"https://orcid.org/0000-0003-4737-9364","affiliations":[{"raw_affiliation_string":"School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063156505","display_name":"Douglas Strathdee","orcid":"https://orcid.org/0000-0003-2959-4327","observed_orcids":["https://orcid.org/0000-0003-2959-4327"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Douglas Strathdee","raw_affiliation_strings":["School of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100635576","display_name":"Masahiko Watanabe","orcid":"https://orcid.org/0000-0001-5037-7138","observed_orcids":["https://orcid.org/0000-0001-5037-7138"]},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahiko Watanabe","raw_affiliation_strings":["Department of Anatomy, Hokkaido University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Hokkaido University School of Medicine","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040327664","display_name":"Andrew M. Bell","orcid":"https://orcid.org/0000-0001-6510-4423","observed_orcids":["https://orcid.org/0000-0001-6510-4423"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew M Bell","raw_affiliation_strings":["School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow"],"raw_orcid":"https://orcid.org/0000-0001-6510-4423","affiliations":[{"raw_affiliation_string":"School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043970902","display_name":"Andrew J. Todd","orcid":"https://orcid.org/0000-0002-3007-6749","observed_orcids":["https://orcid.org/0000-0002-3007-6749"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew J Todd","raw_affiliation_strings":["School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow"],"raw_orcid":"https://orcid.org/0000-0002-3007-6749","affiliations":[{"raw_affiliation_string":"School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031161066","display_name":"Junichi Hachisuka","orcid":"https://orcid.org/0000-0003-3987-4381","observed_orcids":["https://orcid.org/0000-0003-3987-4381"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Junichi Hachisuka","raw_affiliation_strings":["School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow"],"raw_orcid":"https://orcid.org/0000-0003-3987-4381","affiliations":[{"raw_affiliation_string":"School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":2500},"apc_paid":{"value":3000,"currency":"USD","value_usd":2500},"fwci":null,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.008299999870359898,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10914","display_name":"Tactile and Sensory Interactions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trpm8","display_name":"TRPM8","score":0.9319999814033508},{"id":"https://openalex.org/keywords/cold-sensation","display_name":"cold sensation","score":0.47699999809265137},{"id":"https://openalex.org/keywords/primary-afferents","display_name":"primary afferents","score":0.7889999747276306},{"id":"https://openalex.org/keywords/calbindin","display_name":"calbindin","score":0.703000009059906},{"id":"https://openalex.org/keywords/periaqueductal-gray","display_name":"periaqueductal gray","score":0.9340000152587891},{"id":"https://openalex.org/keywords/ventral-posterolateral-nucleus","display_name":"ventral posterolateral nucleus","score":0.8899999856948853},{"id":"https://openalex.org/keywords/thalamus","display_name":"thalamus","score":0.7549999952316284},{"id":"https://openalex.org/keywords/thermoregulation","display_name":"thermoregulation","score":0.7850000262260437},{"id":"https://openalex.org/keywords/thermosensation","display_name":"thermosensation","score":0.6399999856948853},{"id":"https://openalex.org/keywords/synaptic-ultrastructure","display_name":"synaptic ultrastructure","score":0.6309999823570251},{"id":"https://openalex.org/keywords/anterograde-tracing","display_name":"anterograde tracing","score":0.722000002861023}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.8123000264167786},{"id":"https://openalex.org/C172497186","wikidata":"https://www.wikidata.org/wiki/Q328835","display_name":"Somatosensory system","level":2,"score":0.6111999750137329},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.532800018787384},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.5015000104904175},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4771000146865845},{"id":"https://openalex.org/C2779263132","wikidata":"https://www.wikidata.org/wiki/Q2215671","display_name":"Afferent","level":2,"score":0.4675999879837036},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.4471000134944916},{"id":"https://openalex.org/C57493831","wikidata":"https://www.wikidata.org/wiki/Q3134666","display_name":"Projection (relational algebra)","level":2,"score":0.4431999921798706},{"id":"https://openalex.org/C2776378061","wikidata":"https://www.wikidata.org/wiki/Q7317035","display_name":"Retrograde tracing","level":3,"score":0.4050000011920929},{"id":"https://openalex.org/C2910823151","wikidata":"https://www.wikidata.org/wiki/Q936818","display_name":"Parabrachial Nucleus","level":3,"score":0.37950000166893005},{"id":"https://openalex.org/C2779746338","wikidata":"https://www.wikidata.org/wiki/Q6337803","display_name":"Neuroscientist","level":5,"score":0.36480000615119934},{"id":"https://openalex.org/C2779089633","wikidata":"https://www.wikidata.org/wiki/Q4771426","display_name":"Anterograde tracing","level":3,"score":0.3573000133037567},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.3398999869823456},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.3357999920845032},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.3287999927997589},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.31209999322891235},{"id":"https://openalex.org/C31288803","wikidata":"https://www.wikidata.org/wiki/Q2617516","display_name":"Systems neuroscience","level":5,"score":0.3027999997138977},{"id":"https://openalex.org/C17291353","wikidata":"https://www.wikidata.org/wiki/Q6807308","display_name":"Medulla","level":2,"score":0.30230000615119934},{"id":"https://openalex.org/C103378370","wikidata":"https://www.wikidata.org/wiki/Q948647","display_name":"Neuroanatomy","level":2,"score":0.2948000133037567},{"id":"https://openalex.org/C2777989353","wikidata":"https://www.wikidata.org/wiki/Q5985227","display_name":"Lamina","level":2,"score":0.27399998903274536},{"id":"https://openalex.org/C2778013878","wikidata":"https://www.wikidata.org/wiki/Q646150","display_name":"Grey matter","level":4,"score":0.25929999351501465},{"id":"https://openalex.org/C2776032975","wikidata":"https://www.wikidata.org/wiki/Q5018833","display_name":"Calcium imaging","level":3,"score":0.2547999918460846},{"id":"https://openalex.org/C552161191","wikidata":"https://www.wikidata.org/wiki/Q185080","display_name":"Midbrain","level":3,"score":0.2526000142097473},{"id":"https://openalex.org/C50738837","wikidata":"https://www.wikidata.org/wiki/Q781492","display_name":"Optogenetics","level":2,"score":0.2522999942302704},{"id":"https://openalex.org/C2778415016","wikidata":"https://www.wikidata.org/wiki/Q864247","display_name":"Biocytin","level":3,"score":0.25110000371932983},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.2508000135421753}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.7554/elife.109502.1","doi":"https://doi.org/10.7554/elife.109502.1","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.109502.1","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"eLife","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.7554/elife.109502.1","doi":"https://doi.org/10.7554/elife.109502.1","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.109502.1","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"eLife","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1154185311","display_name":null,"funder_award_id":"10.35802/219433","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G1481057710","display_name":"Spinal circuits underlying pathological pain","funder_award_id":"219433/Z/19/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G7617351557","display_name":"The roles of functionally defined populations of lamina I projection neurons","funder_award_id":"MR/V033638/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G7938450967","display_name":null,"funder_award_id":"219433/Z/19/Z","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":69,"referenced_works":["https://openalex.org/W57547414","https://openalex.org/W84808320","https://openalex.org/W1888763924","https://openalex.org/W1972504341","https://openalex.org/W1977871353","https://openalex.org/W1983088365","https://openalex.org/W1988101558","https://openalex.org/W1995330222","https://openalex.org/W1998976848","https://openalex.org/W1999370442","https://openalex.org/W2003400289","https://openalex.org/W2012265686","https://openalex.org/W2025602313","https://openalex.org/W2029909904","https://openalex.org/W2033755379","https://openalex.org/W2038283535","https://openalex.org/W2039463240","https://openalex.org/W2056492757","https://openalex.org/W2059635921","https://openalex.org/W2063283818","https://openalex.org/W2066526154","https://openalex.org/W2073807292","https://openalex.org/W2075449089","https://openalex.org/W2076319015","https://openalex.org/W2079997760","https://openalex.org/W2088268785","https://openalex.org/W2089600276","https://openalex.org/W2091296825","https://openalex.org/W2093934820","https://openalex.org/W2104135721","https://openalex.org/W2107057154","https://openalex.org/W2110314394","https://openalex.org/W2111372811","https://openalex.org/W2147075626","https://openalex.org/W2155276853","https://openalex.org/W2171609889","https://openalex.org/W2381891294","https://openalex.org/W2409408386","https://openalex.org/W2429862435","https://openalex.org/W2561116469","https://openalex.org/W2773803332","https://openalex.org/W2794189368","https://openalex.org/W2895459316","https://openalex.org/W2900830144","https://openalex.org/W2911310882","https://openalex.org/W2949693884","https://openalex.org/W2967170695","https://openalex.org/W2978617872","https://openalex.org/W2979638528","https://openalex.org/W2999978880","https://openalex.org/W3047547106","https://openalex.org/W3096332317","https://openalex.org/W3109914580","https://openalex.org/W3136635931","https://openalex.org/W3198410407","https://openalex.org/W4206271773","https://openalex.org/W4280522045","https://openalex.org/W4281734680","https://openalex.org/W4282043544","https://openalex.org/W4296797528","https://openalex.org/W4362637123","https://openalex.org/W4385835660","https://openalex.org/W4387603301","https://openalex.org/W4389428339","https://openalex.org/W4392378328","https://openalex.org/W4399148758","https://openalex.org/W4408595451","https://openalex.org/W4410161429","https://openalex.org/W4412692497"],"related_works":["https://openalex.org/W7111417834","https://openalex.org/W2033755379","https://openalex.org/W4412692497","https://openalex.org/W2522327444","https://openalex.org/W1999370442","https://openalex.org/W2084890617","https://openalex.org/W3192007091","https://openalex.org/W2065090599","https://openalex.org/W1984182580","https://openalex.org/W2091296825"],"abstract_inverted_index":{"Skin":[0],"cooling":[1],"is":[2,16],"detected":[3],"by":[4],"primary":[5,47],"afferents":[6,80],"that":[7,41,57,103,121,128,168],"express":[8],"the":[9,19,37,62,74,85,110,133,137,141,145,150,155,163,172,179],"Trpm8":[10,79],"channel,":[11],"but":[12],"how":[13],"this":[14,104],"information":[15],"conveyed":[17],"to":[18,36,61,108,124,178],"brain":[20,126],"remains":[21],"poorly":[22],"understood.":[23],"We":[24,71,118],"have":[25],"previously":[26],"identified":[27,66],"a":[28,51,98],"population":[29],"of":[30,76,136,144,154,165,174],"lamina":[31],"I":[32],"projection":[33],"neurons":[34,65,113],"belonging":[35],"anterolateral":[38],"system":[39],"(ALS)":[40],"receive":[42],"numerous":[43],"contacts":[44],"from":[45,78],"Trpm8-expressing":[46],"afferents.":[48],"Here,":[49],"using":[50],"semi-intact":[52],"somatosensory":[53],"preparation,":[54],"we":[55,94],"show":[56,102],"these":[58,82],"cells":[59,83],"correspond":[60],"cold-selective":[63,111],"ALS":[64,112],"in":[67],"previous":[68,91],"physiological":[69],"studies.":[70,117],"also":[72],"confirm":[73],"presence":[75],"synapses":[77],"onto":[81],"at":[84],"ultrastructural":[86],"level.":[87],"Based":[88],"on":[89],"our":[90],"transcriptomic":[92],"findings,":[93],"identify":[95],"calbindin":[96],"as":[97],"molecular":[99],"marker,":[100],"and":[101,149,171],"can":[105],"be":[106],"used":[107],"target":[109],"for":[114],"anterograde":[115],"tracing":[116],"provide":[119,159],"evidence":[120],"they":[122],"project":[123],"3":[125],"regions":[127],"are":[129],"associated":[130],"with":[131],"thermosensation:":[132],"rostralmost":[134],"part":[135,143],"lateral":[138],"parabrachial":[139],"area,":[140],"caudal":[142],"periaqueductal":[146],"grey":[147],"matter,":[148],"ventral":[151],"posterolateral":[152],"nucleus":[153],"thalamus.":[156],"Our":[157],"findings":[158],"important":[160],"insights":[161],"into":[162],"organisation":[164],"neuronal":[166],"circuits":[167],"underlie":[169],"thermoregulation":[170],"perception":[173],"cold":[175],"stimuli":[176],"applied":[177],"skin.":[180]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-12-09T00:00:00"}
