{"id":"https://openalex.org/W4417153277","doi":"https://doi.org/10.5498/wjp.v15.i12.111058","title":"Comorbid depression and autonomic dysfunction reduce lung function in patients with chronic obstructive pulmonary disease","display_name":"Comorbid depression and autonomic dysfunction reduce lung function in patients with chronic obstructive pulmonary disease","publication_year":2025,"publication_date":"2025-11-25","ids":{"openalex":"https://openalex.org/W4417153277","doi":"https://doi.org/10.5498/wjp.v15.i12.111058","pmid":"https://pubmed.ncbi.nlm.nih.gov/41357935"},"language":"en","primary_location":{"id":"doi:10.5498/wjp.v15.i12.111058","doi":"https://doi.org/10.5498/wjp.v15.i12.111058","is_oa":true,"landing_page_url":"https://doi.org/10.5498/wjp.v15.i12.111058","pdf_url":null,"source":{"id":"https://openalex.org/S2764369821","display_name":"World Journal of Psychiatry","issn_l":"2220-3206","issn":["2220-3206"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315735","host_organization_name":"Baishideng Publishing Group","host_organization_lineage":["https://openalex.org/P4310315735"],"host_organization_lineage_names":["Baishideng Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Psychiatry","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.5498/wjp.v15.i12.111058","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Jiang-Bo Li","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jiang-Bo Li","raw_affiliation_strings":["Department of Psychosomatic, Jianyang People's Hospital, Jianyang 641400, Sichuan Province, China. 1015950973@qq.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychosomatic, Jianyang People's Hospital, Jianyang 641400, Sichuan Province, China. 1015950973@qq.com","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064602921","display_name":"Wei Rong","orcid":"https://orcid.org/0000-0002-8550-6574","observed_orcids":["https://orcid.org/0000-0002-8550-6574"]},"institutions":[{"id":"https://openalex.org/I66867065","display_name":"East China Normal University","ror":"https://ror.org/02n96ep67","country_code":"CN","type":"education","lineage":["https://openalex.org/I66867065"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Rong","raw_affiliation_strings":["Department of Clinical Psychology, Wuhu Hospital Affiliated to East China Normal University, Wuhu 241000, Anhui Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Psychology, Wuhu Hospital Affiliated to East China Normal University, Wuhu 241000, Anhui Province, China","institution_ids":["https://openalex.org/I66867065"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"12","first_page":"111058","last_page":"111058"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11083","display_name":"Cardiac Health and Mental Health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.7400000095367432},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.996999979019165},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.8330000042915344},{"id":"https://openalex.org/keywords/lung-function-decline","display_name":"lung function decline","score":0.8080000281333923},{"id":"https://openalex.org/keywords/autonomic-dysfunction","display_name":"autonomic dysfunction","score":0.9440000057220459},{"id":"https://openalex.org/keywords/heart-rate-variability","display_name":"heart rate variability","score":1.0},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.9409999847412109},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.9860000014305115},{"id":"https://openalex.org/keywords/antidepressants","display_name":"antidepressants","score":0.875},{"id":"https://openalex.org/keywords/traditional-chinese-medicine","display_name":"traditional Chinese medicine","score":0.9010000228881836},{"id":"https://openalex.org/keywords/psychotherapy","display_name":"psychotherapy","score":0.8809999823570251},{"id":"https://openalex.org/keywords/cognitive-behavioral-therapy","display_name":"cognitive behavioral therapy","score":0.8059999942779541},{"id":"https://openalex.org/keywords/mindfulness","display_name":"mindfulness","score":0.6959999799728394},{"id":"https://openalex.org/keywords/qigong","display_name":"qigong","score":0.7409999966621399},{"id":"https://openalex.org/keywords/yoga","display_name":"yoga","score":0.8230000138282776},{"id":"https://openalex.org/keywords/lifestyle-intervention","display_name":"lifestyle intervention","score":0.7160000205039978},{"id":"https://openalex.org/keywords/risk-benefit-assessment","display_name":"risk-benefit assessment","score":0.6439999938011169}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8532000184059143},{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.8144999742507935},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.7242000102996826},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.6948999762535095},{"id":"https://openalex.org/C2779177272","wikidata":"https://www.wikidata.org/wiki/Q76560","display_name":"Antidepressant","level":3,"score":0.6140000224113464},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.5684999823570251},{"id":"https://openalex.org/C2780444219","wikidata":"https://www.wikidata.org/wiki/Q341045","display_name":"Mindfulness","level":2,"score":0.4984000027179718},{"id":"https://openalex.org/C2992779976","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Pulmonary disease","level":2,"score":0.48969998955726624},{"id":"https://openalex.org/C3018587741","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung function","level":3,"score":0.4878000020980835},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4830999970436096},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4713999927043915},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.42890000343322754},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.40799999237060547},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.399399995803833},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.39100000262260437},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.38100001215934753},{"id":"https://openalex.org/C71635504","wikidata":"https://www.wikidata.org/wiki/Q933954","display_name":"Heart rate variability","level":4,"score":0.376800000667572},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.37119999527931213},{"id":"https://openalex.org/C188947578","wikidata":"https://www.wikidata.org/wiki/Q200253","display_name":"Traditional Chinese medicine","level":3,"score":0.35109999775886536},{"id":"https://openalex.org/C75603125","wikidata":"https://www.wikidata.org/wiki/Q1877462","display_name":"Pulmonary function testing","level":2,"score":0.29989999532699585},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.29739999771118164},{"id":"https://openalex.org/C2909273474","wikidata":"https://www.wikidata.org/wiki/Q1952420","display_name":"Multimorbidity","level":3,"score":0.28110000491142273},{"id":"https://openalex.org/C3020068993","wikidata":"https://www.wikidata.org/wiki/Q76560","display_name":"Antidepressant medication","level":4,"score":0.2797999978065491},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.27390000224113464},{"id":"https://openalex.org/C2780074459","wikidata":"https://www.wikidata.org/wiki/Q389735","display_name":"Heart disease","level":2,"score":0.2687999904155731},{"id":"https://openalex.org/C2777372248","wikidata":"https://www.wikidata.org/wiki/Q171064","display_name":"Autonomic nervous system","level":4,"score":0.26350000500679016},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.26249998807907104},{"id":"https://openalex.org/C3019858935","wikidata":"https://www.wikidata.org/wiki/Q4340209","display_name":"Depressive symptoms","level":3,"score":0.2558000087738037},{"id":"https://openalex.org/C3020255362","wikidata":"https://www.wikidata.org/wiki/Q747883","display_name":"Physical activity","level":2,"score":0.25459998846054077}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.5498/wjp.v15.i12.111058","doi":"https://doi.org/10.5498/wjp.v15.i12.111058","is_oa":true,"landing_page_url":"https://doi.org/10.5498/wjp.v15.i12.111058","pdf_url":null,"source":{"id":"https://openalex.org/S2764369821","display_name":"World Journal of Psychiatry","issn_l":"2220-3206","issn":["2220-3206"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315735","host_organization_name":"Baishideng Publishing Group","host_organization_lineage":["https://openalex.org/P4310315735"],"host_organization_lineage_names":["Baishideng Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Psychiatry","raw_type":"journal-article"},{"id":"pmid:41357935","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41357935","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World journal of psychiatry","raw_type":"Editorial"},{"id":"pmh:oai:pubmedcentral.nih.gov:12679132","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41357935/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"World J Psychiatry","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.5498/wjp.v15.i12.111058","doi":"https://doi.org/10.5498/wjp.v15.i12.111058","is_oa":true,"landing_page_url":"https://doi.org/10.5498/wjp.v15.i12.111058","pdf_url":null,"source":{"id":"https://openalex.org/S2764369821","display_name":"World Journal of Psychiatry","issn_l":"2220-3206","issn":["2220-3206"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315735","host_organization_name":"Baishideng Publishing Group","host_organization_lineage":["https://openalex.org/P4310315735"],"host_organization_lineage_names":["Baishideng Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Psychiatry","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W2619626234","https://openalex.org/W2756756673","https://openalex.org/W2953165297","https://openalex.org/W2968397605","https://openalex.org/W2996086190","https://openalex.org/W2999133971","https://openalex.org/W3013652236","https://openalex.org/W3043220685","https://openalex.org/W3094225439","https://openalex.org/W3097623787","https://openalex.org/W3104779348","https://openalex.org/W3161306309","https://openalex.org/W3165006303","https://openalex.org/W3165391151","https://openalex.org/W3203290218","https://openalex.org/W4210438487","https://openalex.org/W4220750740","https://openalex.org/W4242045273","https://openalex.org/W4281759127","https://openalex.org/W4285820278","https://openalex.org/W4308114465","https://openalex.org/W4319348885","https://openalex.org/W4362633532","https://openalex.org/W4362634273","https://openalex.org/W4379184324","https://openalex.org/W4383186039","https://openalex.org/W4383668170","https://openalex.org/W4385798383","https://openalex.org/W4386547605","https://openalex.org/W4387157732","https://openalex.org/W4387911539","https://openalex.org/W4388260614","https://openalex.org/W4389299416","https://openalex.org/W4389800850","https://openalex.org/W4390540311","https://openalex.org/W4392978344","https://openalex.org/W4399910372","https://openalex.org/W4402364015","https://openalex.org/W4402394376","https://openalex.org/W4404165724","https://openalex.org/W4404731048","https://openalex.org/W4405004633","https://openalex.org/W4405378865","https://openalex.org/W4407591883","https://openalex.org/W4407701484","https://openalex.org/W4409591761","https://openalex.org/W4409696366","https://openalex.org/W4409905033","https://openalex.org/W4409974774"],"related_works":[],"abstract_inverted_index":{"The":[0],"high":[1],"comorbidity":[2],"rates":[3],"of":[4,27,51,58,82,125],"depression":[5,119],"and":[6,55,61,84,89,106,120,135],"chronic":[7],"obstructive":[8],"pulmonary":[9],"disease":[10],"(COPD)":[11],"have":[12],"garnered":[13],"widespread":[14],"attention.":[15],"As":[16],"a":[17,33],"refractory":[18],"disease,":[19],"its":[20],"long-term":[21,85],"stress":[22],"effects":[23],"exacerbate":[24],"the":[25,52,56,123,151,156],"coexistence":[26],"depression.":[28],"Depression":[29],"is":[30],"linked":[31],"to":[32,78,161],"decline":[34],"in":[35,38],"lung":[36,136],"function":[37],"patients":[39],"with":[40,94],"COPD":[41,96],"through":[42],"reduced":[43],"heart":[44,132],"rate":[45,133],"variability,":[46],"increased":[47],"inflammatory":[48],"cytokines,":[49],"dysregulation":[50],"hypothalamic-pituitary-adrenal":[53],"axis,":[54],"interplay":[57],"various":[59],"biological":[60],"psychological":[62],"factors.":[63],"Sole":[64],"reliance":[65],"on":[66,155],"biomedical":[67,126],"treatment":[68],"cannot":[69],"fully":[70],"counteract":[71],"these":[72],"negative":[73],"effects,":[74],"which":[75],"are":[76],"detrimental":[77],"improving":[79],"patients\u2019":[80],"quality":[81],"life":[83],"prognosis.":[86],"Antidepressant":[87],"medications":[88],"traditional":[90],"Chinese":[91],"medicine":[92],"combined":[93],"conventional":[95],"therapy,":[97,103],"psychotherapy":[98],"(e.g.":[99,109],",":[100,110],"cognitive":[101],"behavioral":[102],"mindfulness":[104],"training),":[105],"lifestyle":[107],"adjustments":[108],"yoga,":[111],"qigong,":[112],"or":[113],"walking)":[114],"can":[115],"not":[116],"only":[117],"alleviate":[118],"compensate":[121],"for":[122],"limitations":[124],"approaches":[127],"but":[128],"also":[129],"help":[130],"improve":[131],"variability":[134],"function.":[137],"In":[138],"this":[139],"editorial,":[140],"we":[141],"suggest":[142],"that":[143],"clinicians,":[144],"when":[145],"prescribing":[146],"antidepressants,":[147],"must":[148],"carefully":[149],"weigh":[150],"benefit-risk":[152],"ratio":[153],"based":[154],"patient\u2019s":[157],"specific":[158],"physical":[159],"condition":[160],"ensure":[162],"precise":[163],"medication":[164],"use.":[165]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2025-11-25T00:00:00"}