{"id":"https://openalex.org/W4417153271","doi":"https://doi.org/10.1093/eurheartj/ehaf925","title":"Fractional flow reserve vs angiography in non-ST- elevation myocardial infarction: long-term results of the FAMOUS-NSTEMI trial","display_name":"Fractional flow reserve vs angiography in non-ST- elevation myocardial infarction: long-term results of the FAMOUS-NSTEMI trial","publication_year":2025,"publication_date":"2025-11-02","ids":{"openalex":"https://openalex.org/W4417153271","doi":"https://doi.org/10.1093/eurheartj/ehaf925","pmid":"https://pubmed.ncbi.nlm.nih.gov/41355352"},"language":"en","primary_location":{"id":"doi:10.1093/eurheartj/ehaf925","doi":"https://doi.org/10.1093/eurheartj/ehaf925","is_oa":true,"landing_page_url":"https://doi.org/10.1093/eurheartj/ehaf925","pdf_url":"https://academic.oup.com/eurheartj/advance-article-pdf/doi/10.1093/eurheartj/ehaf925/65797414/ehaf925.pdf","source":{"id":"https://openalex.org/S181568219","display_name":"European Heart Journal","issn_l":"0195-668X","issn":["0195-668X","1522-9645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/eurheartj/advance-article-pdf/doi/10.1093/eurheartj/ehaf925/65797414/ehaf925.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062232887","display_name":"Colin Berry","orcid":"https://orcid.org/0000-0002-4547-8636","observed_orcids":["https://orcid.org/0000-0002-4547-8636"]},"institutions":[{"id":"https://openalex.org/I2802124073","display_name":"Golden Jubilee National Hospital","ror":"https://ror.org/0103jbm17","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802124073"]},{"id":"https://openalex.org/I32003884","display_name":"British Heart Foundation","ror":"https://ror.org/02wdwnk04","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I32003884"]},{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Colin Berry","raw_affiliation_strings":["British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow , 126 University Place, Glasgow G12 8TA ,","West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK","West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK"],"raw_orcid":"https://orcid.org/0000-0002-4547-8636","affiliations":[{"raw_affiliation_string":"British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow , 126 University Place, Glasgow G12 8TA ,","institution_ids":["https://openalex.org/I32003884","https://openalex.org/I7882870"]},{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","institution_ids":["https://openalex.org/I2802124073"]},{"raw_affiliation_string":"British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK","institution_ids":["https://openalex.org/I32003884","https://openalex.org/I7882870"]},{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK","institution_ids":["https://openalex.org/I2802124073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002237171","display_name":"Bethany Stanley","orcid":"https://orcid.org/0000-0003-3299-4014","observed_orcids":["https://orcid.org/0000-0003-3299-4014"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Bethany Stanley","raw_affiliation_strings":["Robertson Centre for Biostatistics, University of Glasgow , Glasgow ,","Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robertson Centre for Biostatistics, University of Glasgow , Glasgow ,","institution_ids":["https://openalex.org/I7882870"]},{"raw_affiliation_string":"Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090276532","display_name":"Patrycja Duklas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Patrycja Duklas","raw_affiliation_strings":["Robertson Centre for Biostatistics, University of Glasgow , Glasgow ,","Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robertson Centre for Biostatistics, University of Glasgow , Glasgow ,","institution_ids":["https://openalex.org/I7882870"]},{"raw_affiliation_string":"Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067998279","display_name":"Jamie John Layland","orcid":"https://orcid.org/0000-0003-2002-5785","observed_orcids":["https://orcid.org/0000-0003-2002-5785","https://orcid.org/0009-0002-1612-5636"]},"institutions":[{"id":"https://openalex.org/I4210120624","display_name":"Peninsula Health","ror":"https://ror.org/02n5e6456","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210120624"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jamie Layland","raw_affiliation_strings":["Peninsula Health, Peninsula Clinical School, Monash University , Melbourne ,","Peninsula Health, Peninsula Clinical School, Monash University, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peninsula Health, Peninsula Clinical School, Monash University , Melbourne ,","institution_ids":["https://openalex.org/I4210120624","https://openalex.org/I56590836"]},{"raw_affiliation_string":"Peninsula Health, Peninsula Clinical School, Monash University, Melbourne, Australia","institution_ids":["https://openalex.org/I4210120624","https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062922759","display_name":"Keith G. Oldroyd","orcid":"https://orcid.org/0000-0002-7842-3463","observed_orcids":["https://orcid.org/0000-0002-7842-3463"]},"institutions":[{"id":"https://openalex.org/I2802124073","display_name":"Golden Jubilee National Hospital","ror":"https://ror.org/0103jbm17","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802124073"]},{"id":"https://openalex.org/I32003884","display_name":"British Heart Foundation","ror":"https://ror.org/02wdwnk04","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I32003884"]},{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Keith G Oldroyd","raw_affiliation_strings":["British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow , 126 University Place, Glasgow G12 8TA ,","West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK","West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow , 126 University Place, Glasgow G12 8TA ,","institution_ids":["https://openalex.org/I32003884","https://openalex.org/I7882870"]},{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","institution_ids":["https://openalex.org/I2802124073"]},{"raw_affiliation_string":"British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK","institution_ids":["https://openalex.org/I32003884","https://openalex.org/I7882870"]},{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK","institution_ids":["https://openalex.org/I2802124073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030616813","display_name":"Nick P. Curzen","orcid":"https://orcid.org/0000-0001-9651-7829","observed_orcids":["https://orcid.org/0000-0001-9651-7829"]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nick Curzen","raw_affiliation_strings":["Faculty of Medicine, University of Southampton and University Hospital Southampton NHS Foundation Trust , Southampton ,","Faculty of Medicine, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK"],"raw_orcid":"https://orcid.org/0000-0001-9651-7829","affiliations":[{"raw_affiliation_string":"Faculty of Medicine, University of Southampton and University Hospital Southampton NHS Foundation Trust , Southampton ,","institution_ids":["https://openalex.org/I2802965805","https://openalex.org/I43439940"]},{"raw_affiliation_string":"Faculty of Medicine, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805","https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105891859","display_name":"Arvind Sood","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802322126","display_name":"Hairmyres Hospital","ror":"https://ror.org/0488ndr53","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801443577","https://openalex.org/I2802322126"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Arvind Sood","raw_affiliation_strings":["Department of Cardiology, Hairmyres University Hospital , East Kilbride ,","Department of Cardiology, Hairmyres University Hospital, East Kilbride, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Hairmyres University Hospital , East Kilbride ,","institution_ids":["https://openalex.org/I2802322126"]},{"raw_affiliation_string":"Department of Cardiology, Hairmyres University Hospital, East Kilbride, UK","institution_ids":["https://openalex.org/I2802322126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088951868","display_name":"Kanarath P. Balachandran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161870","display_name":"Royal Blackburn Teaching Hospital","ror":"https://ror.org/05261sq16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210161870","https://openalex.org/I67218396"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kanarath Balachandran","raw_affiliation_strings":["Department of Cardiology, Royal Blackburn Hospital , Blackburn ,","Department of Cardiology, Royal Blackburn Hospital, Blackburn, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Royal Blackburn Hospital , Blackburn ,","institution_ids":["https://openalex.org/I4210161870"]},{"raw_affiliation_string":"Department of Cardiology, Royal Blackburn Hospital, Blackburn, UK","institution_ids":["https://openalex.org/I4210161870"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Raj Das","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801924861","display_name":"Freeman Hospital","ror":"https://ror.org/00cdwy346","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801663869","https://openalex.org/I2801924861"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Raj Das","raw_affiliation_strings":["Freeman Hospital, Newcastle Hospitals NHS Foundation Trust , Newcastle ,","Freeman Hospital, Newcastle Hospitals NHS Foundation Trust, Newcastle, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Freeman Hospital, Newcastle Hospitals NHS Foundation Trust , Newcastle ,","institution_ids":["https://openalex.org/I2801924861"]},{"raw_affiliation_string":"Freeman Hospital, Newcastle Hospitals NHS Foundation Trust, Newcastle, UK","institution_ids":["https://openalex.org/I2801924861"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102936800","display_name":"Shahid Junejo","orcid":"https://orcid.org/0000-0003-3808-0408","observed_orcids":["https://orcid.org/0000-0003-3808-0408"]},"institutions":[{"id":"https://openalex.org/I4210135167","display_name":"South Tyneside and Sunderland NHS Foundation Trust","ror":"https://ror.org/044j2cm68","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I4210135167"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Shahid Junejo","raw_affiliation_strings":["Department of Cardiology, South Tyneside and Sunderland NHS Foundation Trust , Sunderland ,","Department of Cardiology, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, South Tyneside and Sunderland NHS Foundation Trust , Sunderland ,","institution_ids":["https://openalex.org/I4210135167"]},{"raw_affiliation_string":"Department of Cardiology, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, UK","institution_ids":["https://openalex.org/I4210135167"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061665476","display_name":"Hany Eteiba","orcid":"https://orcid.org/0000-0003-2200-8567","observed_orcids":["https://orcid.org/0000-0003-2200-8567"]},"institutions":[{"id":"https://openalex.org/I2802124073","display_name":"Golden Jubilee National Hospital","ror":"https://ror.org/0103jbm17","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802124073"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hany Eteiba","raw_affiliation_strings":["West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK"],"raw_orcid":"https://orcid.org/0000-0003-2200-8567","affiliations":[{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","institution_ids":["https://openalex.org/I2802124073"]},{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK","institution_ids":["https://openalex.org/I2802124073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075597955","display_name":"Mitchell M Lindsay","orcid":"https://orcid.org/0000-0002-4654-712X","observed_orcids":["https://orcid.org/0000-0002-4654-712X"]},"institutions":[{"id":"https://openalex.org/I2802124073","display_name":"Golden Jubilee National Hospital","ror":"https://ror.org/0103jbm17","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802124073"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mitchell Lindsay","raw_affiliation_strings":["West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","institution_ids":["https://openalex.org/I2802124073"]},{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK","institution_ids":["https://openalex.org/I2802124073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085009090","display_name":"Aadil Shaukat","orcid":"https://orcid.org/0000-0001-7409-6859","observed_orcids":["https://orcid.org/0000-0001-7409-6859"]},"institutions":[{"id":"https://openalex.org/I2802124073","display_name":"Golden Jubilee National Hospital","ror":"https://ror.org/0103jbm17","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802124073"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Aadil Shaukat","raw_affiliation_strings":["West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","institution_ids":["https://openalex.org/I2802124073"]},{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK","institution_ids":["https://openalex.org/I2802124073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039364754","display_name":"Stuart Watkins","orcid":"https://orcid.org/0000-0003-1579-6294","observed_orcids":["https://orcid.org/0000-0003-1579-6294"]},"institutions":[{"id":"https://openalex.org/I2802124073","display_name":"Golden Jubilee National Hospital","ror":"https://ror.org/0103jbm17","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802124073"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stuart Watkins","raw_affiliation_strings":["West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK"],"raw_orcid":"https://orcid.org/0000-0003-1579-6294","affiliations":[{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","institution_ids":["https://openalex.org/I2802124073"]},{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK","institution_ids":["https://openalex.org/I2802124073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016095791","display_name":"Ian Ford","orcid":"https://orcid.org/0000-0001-5927-1823","observed_orcids":["https://orcid.org/0000-0001-5927-1823"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ian Ford","raw_affiliation_strings":["Robertson Centre for Biostatistics, University of Glasgow , Glasgow ,","Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK"],"raw_orcid":"https://orcid.org/0000-0001-5927-1823","affiliations":[{"raw_affiliation_string":"Robertson Centre for Biostatistics, University of Glasgow , Glasgow ,","institution_ids":["https://openalex.org/I7882870"]},{"raw_affiliation_string":"Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008435118","display_name":"Richard Good","orcid":"https://orcid.org/0000-0002-3906-1025","observed_orcids":["https://orcid.org/0000-0002-3906-1025"]},"institutions":[{"id":"https://openalex.org/I2802124073","display_name":"Golden Jubilee National Hospital","ror":"https://ror.org/0103jbm17","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802124073"]},{"id":"https://openalex.org/I32003884","display_name":"British Heart Foundation","ror":"https://ror.org/02wdwnk04","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I32003884"]},{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Richard I S Good","raw_affiliation_strings":["British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow , 126 University Place, Glasgow G12 8TA ,","West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK","West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow , 126 University Place, Glasgow G12 8TA ,","institution_ids":["https://openalex.org/I32003884","https://openalex.org/I7882870"]},{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank ,","institution_ids":["https://openalex.org/I2802124073"]},{"raw_affiliation_string":"British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK","institution_ids":["https://openalex.org/I32003884","https://openalex.org/I7882870"]},{"raw_affiliation_string":"West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK","institution_ids":["https://openalex.org/I2802124073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057223605","display_name":"Robert A. Henderson","orcid":"https://orcid.org/0000-0002-0319-3691","observed_orcids":["https://orcid.org/0000-0002-0319-3691","https://orcid.org/0000-0002-3730-1232"]},"institutions":[{"id":"https://openalex.org/I1334287468","display_name":"Nottingham University Hospitals NHS Trust","ror":"https://ror.org/05y3qh794","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1334287468"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Robert Henderson","raw_affiliation_strings":["Trent Cardiac Centre, Nottingham University Hospitals NHS Trust , Nottingham ,","Trent Cardiac Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Trent Cardiac Centre, Nottingham University Hospitals NHS Trust , Nottingham ,","institution_ids":["https://openalex.org/I1334287468"]},{"raw_affiliation_string":"Trent Cardiac Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK","institution_ids":["https://openalex.org/I1334287468"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078354802","display_name":"Alex McConnachie","orcid":"https://orcid.org/0000-0002-7262-7000","observed_orcids":["https://orcid.org/0000-0002-7262-7000"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alex McConnachie","raw_affiliation_strings":["Robertson Centre for Biostatistics, University of Glasgow , Glasgow ,","Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK"],"raw_orcid":"https://orcid.org/0000-0002-7262-7000","affiliations":[{"raw_affiliation_string":"Robertson Centre for Biostatistics, University of Glasgow , Glasgow ,","institution_ids":["https://openalex.org/I7882870"]},{"raw_affiliation_string":"Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK","institution_ids":["https://openalex.org/I7882870"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5062232887"],"corresponding_institution_ids":["https://openalex.org/I2802124073","https://openalex.org/I32003884","https://openalex.org/I7882870"],"apc_list":{"value":5240,"currency":"EUR","value_usd":5922},"apc_paid":{"value":5240,"currency":"EUR","value_usd":5922},"fwci":1.737,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.86713589,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"47","issue":"12","first_page":"1487","last_page":"1490"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fractional-flow-reserve","display_name":"fractional flow reserve","score":0.9879999756813049},{"id":"https://openalex.org/keywords/non-st-elevation-myocardial-infarction","display_name":"non-ST-elevation myocardial infarction","score":0.9509999752044678},{"id":"https://openalex.org/keywords/coronary-revascularization","display_name":"coronary revascularization","score":0.7770000100135803},{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention","display_name":"percutaneous coronary intervention","score":0.7979999780654907},{"id":"https://openalex.org/keywords/coronary-artery-bypass-grafting","display_name":"coronary artery bypass grafting","score":0.8690000176429749},{"id":"https://openalex.org/keywords/major-adverse-cardiovascular-events","display_name":"major adverse cardiovascular events","score":0.949999988079071},{"id":"https://openalex.org/keywords/long-term-outcomes","display_name":"long-term outcomes","score":0.675000011920929},{"id":"https://openalex.org/keywords/culprit-lesion","display_name":"culprit lesion","score":0.3619999885559082},{"id":"https://openalex.org/keywords/microvascular-dysfunction","display_name":"microvascular dysfunction","score":0.7160000205039978},{"id":"https://openalex.org/keywords/plaque-characteristics","display_name":"plaque characteristics","score":0.5870000123977661},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.37700000405311584},{"id":"https://openalex.org/keywords/coronary-microvascular-dysfunction","display_name":"coronary microvascular dysfunction","score":0.32199999690055847}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9674999713897705},{"id":"https://openalex.org/C2777987666","wikidata":"https://www.wikidata.org/wiki/Q1440572","display_name":"Fractional flow reserve","level":4,"score":0.870199978351593},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7763000130653381},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7336000204086304},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.5386000275611877},{"id":"https://openalex.org/C37054046","wikidata":"https://www.wikidata.org/wiki/Q641888","display_name":"Elevation (ballistics)","level":2,"score":0.5030999779701233},{"id":"https://openalex.org/C3019004856","wikidata":"https://www.wikidata.org/wiki/Q42297149","display_name":"Coronary angiography","level":3,"score":0.4684000015258789},{"id":"https://openalex.org/C38349280","wikidata":"https://www.wikidata.org/wiki/Q1434290","display_name":"Flow (mathematics)","level":2,"score":0.4138999879360199},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.3693000078201294},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.33169999718666077},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.2833999991416931},{"id":"https://openalex.org/C2778707443","wikidata":"https://www.wikidata.org/wiki/Q3936479","display_name":"Coronary flow reserve","level":3,"score":0.27250000834465027},{"id":"https://openalex.org/C2776291336","wikidata":"https://www.wikidata.org/wiki/Q7394928","display_name":"ST elevation","level":3,"score":0.266400009393692},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.2547999918460846},{"id":"https://openalex.org/C2780088680","wikidata":"https://www.wikidata.org/wiki/Q7281300","display_name":"Radionuclide angiography","level":4,"score":0.2547999918460846}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1093/eurheartj/ehaf925","doi":"https://doi.org/10.1093/eurheartj/ehaf925","is_oa":true,"landing_page_url":"https://doi.org/10.1093/eurheartj/ehaf925","pdf_url":"https://academic.oup.com/eurheartj/advance-article-pdf/doi/10.1093/eurheartj/ehaf925/65797414/ehaf925.pdf","source":{"id":"https://openalex.org/S181568219","display_name":"European Heart Journal","issn_l":"0195-668X","issn":["0195-668X","1522-9645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal","raw_type":"journal-article"},{"id":"pmid:41355352","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41355352","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European heart journal","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.gla.ac.uk:370839","doi":null,"is_oa":true,"landing_page_url":"https://eprints.gla.ac.uk/view/journal_volume/European_Heart_Journal.html>,","pdf_url":null,"source":{"id":"https://openalex.org/S4210235606","display_name":"ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)","issn_l":"2622-8912","issn":["2622-8912","2622-8920"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/I4405259220","host_organization_name":"Institut Agama Islam Negeri Langsa","host_organization_lineage":["https://openalex.org/I4405259220"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Articles"},{"id":"pmh:oai:eprints.soton.ac.uk:508425","doi":null,"is_oa":true,"landing_page_url":"https://eprints.soton.ac.uk/id/eprint/508425/1/FAMOUS-NSTEMI_Trial-FUp_2025-09-10_Clean.docx","pdf_url":"https://eprints.soton.ac.uk/508425/2/ehaf925.pdf","source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13008471","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41355352/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13008471/pdf/ehaf925.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Eur Heart J","raw_type":"Text"},{"id":"doi:10.25405/ncl.34544919","doi":"https://doi.org/10.25405/ncl.34544919","is_oa":true,"landing_page_url":"https://doi.org/10.25405/ncl.34544919","pdf_url":null,"source":{"id":"https://openalex.org/S4306402485","display_name":"Newcastle University ePrints (Newcastle Univesity)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I84884186","host_organization_name":"Newcastle University","host_organization_lineage":["https://openalex.org/I84884186"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.25405/ncl.34544919.v1","doi":"https://doi.org/10.25405/ncl.34544919.v1","is_oa":true,"landing_page_url":"https://doi.org/10.25405/ncl.34544919.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306402485","display_name":"Newcastle University ePrints (Newcastle Univesity)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I84884186","host_organization_name":"Newcastle University","host_organization_lineage":["https://openalex.org/I84884186"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.1093/eurheartj/ehaf925","doi":"https://doi.org/10.1093/eurheartj/ehaf925","is_oa":true,"landing_page_url":"https://doi.org/10.1093/eurheartj/ehaf925","pdf_url":"https://academic.oup.com/eurheartj/advance-article-pdf/doi/10.1093/eurheartj/ehaf925/65797414/ehaf925.pdf","source":{"id":"https://openalex.org/S181568219","display_name":"European Heart Journal","issn_l":"0195-668X","issn":["0195-668X","1522-9645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2085333841","display_name":"The BHF FAMOUS-NSTEMI long-term follow-up study","funder_award_id":"PG/18/52/33892","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"},{"id":"https://openalex.org/G642378660","display_name":"Fractional flow reserve versus angiographically guided management to optimise outcomes in unstable coronary syndromes: a developmental clinical study. ,","funder_award_id":"PG/11/55/28999","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"}],"funders":[{"id":"https://openalex.org/F4320319992","display_name":"British Heart Foundation","ror":"https://ror.org/02wdwnk04"},{"id":"https://openalex.org/F4320320064","display_name":"Scottish Funding Council","ror":"https://ror.org/056bwcz71"},{"id":"https://openalex.org/F4320332389","display_name":"St. Jude Medical","ror":"https://ror.org/00t9de449"},{"id":"https://openalex.org/F4320333259","display_name":"Abbott Vascular","ror":"https://ror.org/05d67dc31"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4417153271.pdf","grobid_xml":"https://content.openalex.org/works/W4417153271.grobid-xml"},"referenced_works_count":10,"referenced_works":["https://openalex.org/W1484080302","https://openalex.org/W2115416118","https://openalex.org/W2150801605","https://openalex.org/W2320707747","https://openalex.org/W2336211246","https://openalex.org/W2955390345","https://openalex.org/W3135498932","https://openalex.org/W4386153206","https://openalex.org/W4386704149","https://openalex.org/W4409030151"],"related_works":[],"abstract_inverted_index":{"Complete":[0],"revascularization":[1,46,140,191,465,768,824,849,857],"may":[2,19,28,54],"be":[3,298,1391],"considered":[4],"for":[5,190,244,310,442,513,534,823,908,968,1237,1288,1337],"patients":[6,79,133,159,906,1081,1146,1247],"presenting":[7],"with":[8,80,127,134,489,670,792,843,912,1082,1147,1264,1291,1398],"non-ST-segment":[9],"elevation":[10],"myocardial":[11,245,443],"infarction":[12,246,444],"(NSTEMI).1,2":[13],"Visual":[14],"assessment":[15],"of":[16,45,87,264,307,315,331,338,344,371,403,416,423,437,497,562,577,648,658,780,787,875,931,1016,1073,1099,1138,1280,1385,1401],"the":[17,85,97,102,147,165,265,335,365,369,378,400,427,514,535,540,551,565,568,636,643,653,663,702,738,781,788,820,863,870,937,942,972,987,1043,1050,1056,1066,1070,1121,1131,1135,1164,1171,1246,1254,1262,1265,1278,1316,1399,1402,1416,1427,1438,1447,1463,1466],"angiogram":[18],"misclassify":[20],"culprit":[21,212,945],"lesion":[22,946],"status,3":[23],"and":[24,57,175,216,253,283,313,323,341,346,357,383,405,462,475,477,484,505,516,529,548,623,638,656,832,855,883,940,953,971,1001,1046,1167,1213,1226,1234,1240,1253,1285,1308,1335,1339,1346,1349,1351,1357,1368,1371,1397,1405,1423,1460,1462],"a":[25,176,269,291,303,414,435,667,846,1412,1434],"functional":[26,929],"approach":[27],"guide":[29],"revascularization.4":[30],"In":[31,904],"stable":[32],"coronary":[33,67,139,194,198,856,934],"artery":[34,199,935],"disease,":[35],"fractional":[36],"flow":[37,984],"reserve":[38],"(FFR)":[39],"values":[40],">0.80":[41],"indicate":[42,421],"that":[43,262,1268],"deferral":[44],"is":[47,418,1064,1129,1275,1465],"safe5;":[48],"however,":[49],"in":[50,63,77,96,101,132,146,156,161,164,208,218,326,652,662,701,737,777,819,848,862,869,948,975,996,999,1007,1010,1039,1042,1049,1160,1163,1170,1250,1271],"NSTEMI,":[51],"microvascular":[52],"dysfunction":[53],"limit":[55],"hyperaemia,6,7":[56],"plaque":[58],"characteristics":[59],"are":[60,532,1458],"prognostically":[61],"important":[62],"non-flow":[64],"limiting":[65],"(FFR-negative)":[66],"disease.8,9":[68],"The":[69,227,495,520,560,696,731,815,923,950,963,1059,1124,1180,1216,1376,1442,1453],"FAMOUS-NSTEMI":[70],"trial":[71,155,964,1443,1455],"assessed":[72,353,549],"FFR-guided":[73,98,130,183,515,536,637,654,703,739,782,915],"vs":[74,107,680,707,743,784,802,853,866,890],"angiography-guided":[75,103,128,639,664,789,913],"management":[76,92,131,830,916,1239],"350":[78,157,592,988],"NSTEMI.10":[81],"By":[82],"12":[83],"months,":[84],"percentage":[86],"participants":[88,288,488,498,611,651,661,993,1004,1041,1048,1162,1169],"treated":[89],"by":[90,192,399,470,480,769,1025,1109,1277,1326,1411,1433,1446],"medical":[91,332,829],"only":[93],"was":[94,173,181,187,205,222,231,397,587,699,735,775,965,978,1037,1158,1324,1409,1431,1444],"higher":[95,700,736],"group":[99,104,215,356,537,665,704,740,783,790,865,873,1028,1045,1112,1166,1179],"than":[100],"[40":[105],"(22.7%)":[106,786],"23(13.2%),":[108],"difference":[109,974],"9.5%":[110],"(95%":[111,685,808,896],"CI":[112,809],"1.4%,":[113],"17.7%),":[114],"P":[115,691,715,728,751,764,812,901],"=":[116,613,692,716,724,726,729,752,760,762,765,813,902,1030,1062,1127,1152],".022;":[117],"relative":[118,538],"risk":[119,673,795],"1.72":[120],"(1.08,":[121],"2.82)].":[122],"We":[123,260,1229,1243],"hypothesized":[124],"that,":[125],"compared":[126,911],"management,":[129,914],"recent":[135],"NSTEMI":[136,158,905],"would":[137,267,289,297],"reduce":[138,919],"without":[141,845],"increasing":[142],"adverse":[143,234,920],"clinical":[144,178,329,833,956,1454],"outcomes":[145,179,360,374,834],"longer":[148],"term.":[149],"A":[150],"prospective":[151],"1:1":[152],"randomized,":[153],"controlled":[154],"enrolled":[160,995,1006],"six":[162],"hospitals":[163,998,1009],"UK":[166,1448],"from":[167,274,320,364,564,1018,1065,1101,1130,1315,1341,1354,1364,1374,1415,1437],"October":[168],"2011":[169],"to":[170,280,301,411,420,539,604,635,828,1387],"May":[171],"2013":[172],"undertaken,10":[174],"longer-term":[177],"analysis":[180],"prespecified.10":[182],"group:":[184],"FFR":[185,203,221],"\u22640.80":[186],"an":[188,500,878,932,1331],"indication":[189],"percutaneous":[193],"intervention":[195,1044,1165],"(PCI)":[196],"or":[197,211,242,247,440,449,575,771,826,844],"bypass":[200],"surgery":[201],"(CABG).":[202],"guidance":[204],"not":[206,225,839,918,966,979,1380],"recommended":[207],"angiographically":[209],"severe":[210],"lesions.":[213],"Angiography-guided":[214],"blinding:":[217],"this":[219,1251,1272],"group,":[220,655],"measured":[223],"but":[224],"disclosed.10":[226],"prespecified":[228],"primary":[229,379,401,644],"outcome":[230,645],"spontaneous":[232],"major":[233],"cardiovascular":[235,240,438,732,921,976,1107],"events":[236,385],"(MACE)":[237],"defined":[238,376,389,398,433],"as":[239,434],"death":[241,396,404,439,574,697,733,1023,1108],"hospitalization":[243,441,570],"heart":[248,450],"failure.":[249],"Cardiovascular":[250,395],"death,":[251],"stroke,":[252],"transient":[254],"ischaemic":[255],"attack":[256],"were":[257,318,349,352,375,388,432,493,511,546,601,835,838,994,1005,1185,1221,1269],"secondary":[258],"outcomes.":[259,922],"estimated":[261],"5%":[263,552],"population":[266],"experience":[268,290],"first":[270],"MACE":[271,431,668,837],"event":[272,506,884],"annually":[273],"year":[275],"two":[276,997],"onwards":[277],"(follow-up":[278],"duration":[279,561],"10":[281,909],"years),":[282],"at":[284,503,550,672,794,881],"least":[285],"108":[286],"(31%)":[287],"MACE.":[292],"With":[293],"105":[294],"events,":[295],"there":[296],"80%":[299],"power":[300],"detect":[302],"hazard":[304,524,683,805,894],"ratio":[305,525,684,806,895],"(HR)":[306],"0.58.":[308],"Data":[309,1389],"vital":[311],"status":[312],"episodes":[314],"hospital":[316,1020,1103],"care":[317,518,542],"obtained":[319],"NHS":[321,324,1471],"Scotland":[322],"Digital":[325],"England.":[327,1011],"Standard":[328],"coding":[330],"records":[333],"per":[334,508,675,797,886],"International":[336],"Classification":[337,343],"Disease":[339],"(ICD)-10":[340],"OPCS":[342],"Interventions":[345],"Procedures":[347],"(OPCS)-4":[348],"used.":[350],"Associations":[351],"between":[354,817,841],"randomized":[355,487,593,634,989,1026,1075,1080,1110,1140,1145],"linkage":[358,490,1036,1083,1148,1157],"health":[359,607,1034,1155],"occurring":[361],"after":[362,567,773],"discharge":[363,571,774,1021,1105],"index":[366,569,938,1019,1102],"admission":[367],"until":[368,573,1022,1106],"end":[370,576],"follow-up.":[372,1090,1117],"Health":[373],"using":[377,390,406,555],"ICD-10":[380,407],"code":[381,429],"recorded,":[382],"procedural":[384],"(CABG,":[386],"PCI)":[387],"all":[391,424,1079,1144],"recorded":[392],"OPCS-4":[393,471,481],"codes.":[394],"cause":[402],"codes":[408,446,453,472,482],"I00.x":[409],"through":[410],"I99.x,":[412],"where":[413],"suffix":[415],"\u2018.x\u2019":[417],"used":[419,1270],"inclusion":[422],"sub-codes":[425],"within":[426],"given":[428],"range.":[430],"composite":[436],"(ICD-10":[445,452],"I21.x,":[447],"I22.x)":[448],"failure":[451],"I50.0,":[454],"I50.1,":[455],"I50.9,":[456],"I42.0,":[457],"I42.9,":[458],"I11.0,":[459],"I25.5,":[460],"I13.2,":[461],"I13.0).":[463],"Coronary":[464,767],"procedures":[466],"included":[467],"PCI,":[468],"identified":[469,479],"K49.x,":[473],"K50.x,":[474],"K75.x,":[476],"CABG,":[478],"K40.x\u2013K46.x":[483],"K47.1.":[485],"All":[486,544],"data":[491,1084,1149,1238],"available":[492,1085,1150,1393],"included.":[494],"number":[496],"experiencing":[499,877],"event,":[501,879],"person-years":[502,510,880],"risk,":[504,882],"rate":[507,698,734,885],"1000":[509,676,798,887],"calculated":[512],"standard":[517,541],"groups.":[519],"Cox":[521,713,749,893],"regression":[522,714,750],"model":[523],"(HR),":[526],"95%":[527],"CI,":[528],"corresponding":[530],"P-value":[531,1060,1125],"presented":[533],"group.":[543,1077,1092,1094,1142,1176],"tests":[545],"two-tailed":[547],"significance":[553],"level":[554],"R":[556],"Studio":[557],"version":[558],"4.0.0.":[559],"follow-up":[563,578],"day":[566],"date":[572],"(data":[579],"extract":[580],"31":[581],"March":[582],"2022),":[583],"whichever":[584],"occurred":[585],"earliest,":[586],"9.3":[588,1087,1114],"(9.0\u20139.8)":[589,1088,1115],"years.":[590],"Of":[591,609,986],"participants,":[594,990],"324":[595,1031],"(93%)":[596],"had":[597,632],"complete":[598],"follow-up,":[599],"i.e.":[600],"successfully":[602],"linked":[603],"their":[605],"electronic":[606,1033,1154],"records.":[608],"these":[610,961],"(n":[612,1029,1151],"324),":[614],"161":[615,649,1040,1161],"(49.7%)":[616],"(mean":[617,626],"age":[618,627],"62.5":[619],"years,":[620,629,910],"73.3%":[621],"males)":[622,631],"163":[624,659,1047,1168],"(50.3%)":[625],"62.1":[628],"71.8%":[630],"been":[633],"groups,":[640],"respectively.":[641],"For":[642],"(MACE),":[646],"45":[647],"(28.0%)":[650],"38":[657],"(23.3%)":[660],"experienced":[666],"[number":[669,791,874],"event/person-years":[671,793],"(rate":[674,796],"person-years):":[677,799],"45/1197":[678],"(37.6)":[679],"38/1284":[681],"(29.6);":[682],"confidence":[686],"interval)":[687],"1.26":[688],"(0.82,":[689],"1.95);":[690],".288]":[693],"(Figure":[694],"1).":[695],"[45/1337":[705],"(33.7)":[706],"33/1426":[708],"(23.1);":[709],"1.47":[710],"(0.94,":[711],"2.30);":[712],".094;":[717],"Kaplan\u2013Meier":[718,754,1013,1096],"log-rank":[719,755,1067,1132],"test,":[720,756],"\u03c72":[721,757],"(1,":[722,758],"N":[723,759],"324)":[725,761],"2.83,":[727],".092].":[730],"[21/1337":[741],"(15.7)":[742],"11/1426":[744],"(7.7);":[745],"2.05":[746],"(0.99,":[747],"4.26);":[748],".054;":[753],"3.88,":[763],".049].":[766],"PCI":[770],"CABG":[772],"performed":[776],"26/161":[778],"(16.1%)":[779],"37/163":[785],"26/1187":[800],"(21.9)":[801],"37/1208":[803],"(30.6);":[804],"0.72":[807],".43,":[810],"1.18);":[811],".193].":[814],"associations":[816],"change":[818,847,864,872],"initial":[821],"plan":[822],"(PCI":[825],"CABG)":[827],"post-randomization":[831],"assessed.":[836],"different":[840],"groups":[842],"treatment":[850,1027,1076,1111,1141],"decision":[851],"post-":[852],"pre-randomization,":[854],"remained":[858],"reduced":[859],"(10/34":[860],"(29.4%)":[861],"35/127":[867],"(27.6%)":[868],"no":[871],"individuals":[876],"years\u201410/253":[888],"(39.5)":[889],"35/944":[891],"(37.1);":[892],"CI)":[897],"1.08":[898],"(0.54,":[899],"2.19);":[900],".824].":[903],"followed":[907],"did":[917],"results":[924],"support":[925,1373],"guideline":[926],"recommendations":[927],"against":[928],"evaluation":[930],"infarct-related":[933],"during":[936,1086,1113],"procedure1,2":[939],"highlight":[941],"uncertainty":[943],"about":[944],"classification":[947],"NSTEMI.8":[949],"Complete-NSTEMI":[951],"(NCT05786131)":[952],"COMPLETE-2":[954],"(NCT05701358)":[955],"trials":[957],"will":[958],"expand":[959],"on":[960,1394],"findings.":[962],"powered":[967],"mortality":[969],"endpoints":[970],"between-group":[973],"deaths":[977],"statistically":[980],"significant.":[981],"A)":[982],"CONSORT":[983],"diagram.":[985],"251":[991],"(72%)":[992],"Scotland,":[1000],"99":[1002],"(28%)":[1003],"four":[1008],"B)":[1012],"survival":[1014,1057,1071,1097,1122,1136],"plot":[1015,1098],"time":[1017,1100],"(all-cause)":[1024],"individuals;":[1032],"record":[1035,1156],"achieved":[1038,1159],"control":[1051,1172],"group).":[1052,1173],"Solid":[1053,1118],"lines":[1054,1119],"present":[1055,1120],"estimates.":[1058,1123],"(P":[1061,1126],".092)":[1063],"test":[1068,1133],"comparing":[1069,1134],"curve":[1072,1137],"each":[1074,1139],"Population:":[1078,1143],"years":[1089,1116],"Intervention\u2014FFR-guided":[1091],"Control\u2014angiography-guided":[1093],"C)":[1095],"stay":[1104],".049)":[1128],"324;":[1153],"Intervention":[1174],"(green)\u2014FFR-guided":[1175],"Control":[1177],"(blue)\u2014angiography-guided":[1178],"Trial":[1181],"Steering":[1182],"Committee":[1183,1219],"members":[1184,1220],"Robert":[1186],"Henderson":[1187],"(Chair),":[1188],"Kanarath":[1189],"Balachandran,":[1190],"Colin":[1191],"Berry":[1192],"(Principal":[1193],"Investigator),":[1194],"Gordon":[1195],"Baird":[1196],"(Patient":[1197],"Advocate),":[1198],"Anna":[1199],"O'Donnell,":[1200],"Arvind":[1201],"Sood,":[1202],"Nick":[1203],"Curzen,":[1204],"Raj":[1205],"Das,":[1206],"Ian":[1207],"Ford,":[1208],"Jamie":[1209],"Layland,":[1210],"Shahid":[1211],"Junejo,":[1212],"Keith":[1214],"Oldroyd.":[1215],"Clinical":[1217],"Event":[1218],"Andrew":[1222,1224],"Hannah,":[1223],"Stewart,":[1225],"Francis":[1227],"Dunn.":[1228],"thank":[1230],"Elizabeth":[1231],"Thomson,":[1232],"BSc,":[1233],"Robbie":[1235],"Wilson":[1236],"quality":[1241],"assurance.":[1242],"gratefully":[1244],"acknowledge":[1245],"who":[1248,1256],"participated":[1249],"study":[1252],"staff":[1255],"supported":[1257,1410,1432],"it.":[1258],"Abbott":[1259,1292,1355,1424],"Vascular":[1260,1356,1425],"provided":[1261,1426],"sites":[1263],"diagnostic":[1266,1428],"guidewires":[1267],"study.":[1273],"C.B.":[1274,1311,1430],"employed":[1276,1325],"University":[1279],"Glasgow":[1281],"which":[1282],"holds":[1283],"consultancy":[1284,1340],"research":[1286,1313,1333],"agreements":[1287],"his":[1289],"work":[1290,1408],"Vascular,":[1293],"AstraZeneca,":[1294,1367],"Auxilius":[1295],"Pharma,":[1296],"Boehringer":[1297,1365],"Ingelheim,":[1298,1366],"CorFlow,":[1299],"Coroventis,":[1300],"Edwards":[1301],"Lifesciences,":[1302],"MSD,":[1303],"Novartis,":[1304],"Servier,":[1305],"Siemens":[1306],"Healthcare,":[1307],"Zoll":[1309],"Medical.":[1310],"receives":[1312],"funding":[1314],"British":[1317,1417],"Heart":[1318,1418],"Foundation":[1319,1419],"grant":[1320,1334],"(RE/18/6/34217,":[1321],"PG/18/52/33892).":[1322],"K.G.O.":[1323],"Biosensors.":[1327],"N.C.":[1328],"has":[1329,1360],"received":[1330,1361],"unrestricted":[1332],"fees":[1336,1353,1363],"lectures":[1338],"Haemonetics,":[1342],"Boston":[1343],"scientific,":[1344],"Heartflow,":[1345],"Beckman":[1347],"Coulter":[1348],"consulting":[1350],"speaker":[1352,1362],"Heartflow.":[1358],"K.B.":[1359],"Daichii":[1369],"Sankyo":[1370],"travel":[1372],"Abbott.":[1375],"other":[1377],"authors":[1378],"do":[1379],"have":[1381],"any":[1382],"potential":[1383],"conflict":[1384],"interest":[1386],"declare.":[1388],"can":[1390],"made":[1392],"reasonable":[1395],"request":[1396],"agreement":[1400],"steering":[1403],"committee":[1404],"sponsor.":[1406],"This":[1407],"Project":[1413],"Grant":[1414,1420],"(PG/11/55/28999;":[1421],"PG/18/52/33892)":[1422],"guidewires.":[1429],"Senior":[1435],"Fellowship":[1436],"Scottish":[1439],"Funding":[1440],"Council.":[1441],"approved":[1445],"National":[1449,1469],"Research":[1450],"Ethics":[1451],"Service.":[1452],"registration":[1456],"numbers":[1457],"NCT01764334":[1459],"ISRCTN97489534,":[1461],"sponsor":[1464],"Golden":[1467],"Jubilee":[1468],"Hospital,":[1470],"Scotland.":[1472]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-12-09T00:00:00"}
