{"id":"https://openalex.org/W4416900359","doi":"https://doi.org/10.1158/2159-8290.30761408","title":"Table S6 from Functional Mapping of Epigenomic Regulators Uncovers Coordinated Tumor Suppression by the HBO1 and MLL1 Complexes","display_name":"Table S6 from Functional Mapping of Epigenomic Regulators Uncovers Coordinated Tumor Suppression by the HBO1 and MLL1 Complexes","publication_year":2025,"publication_date":"2025-12-02","ids":{"openalex":"https://openalex.org/W4416900359","doi":"https://doi.org/10.1158/2159-8290.30761408"},"language":"en","primary_location":{"id":"doi:10.1158/2159-8290.30761408","doi":"https://doi.org/10.1158/2159-8290.30761408","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2159-8290.30761408","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/2159-8290.30761408","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006995907","display_name":"Yuning J. Tang","orcid":"https://orcid.org/0009-0006-7037-2901","observed_orcids":["https://orcid.org/0009-0006-7037-2901","https://orcid.org/0009-0007-9488-3076"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yuning J. Tang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0006-7037-2901","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057259259","display_name":"Haiqing Xu","orcid":"https://orcid.org/0000-0002-9124-3192","observed_orcids":["https://orcid.org/0000-0002-9124-3192","https://orcid.org/0000-0003-2570-8569"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Haiqing Xu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9124-3192","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104044093","display_name":"Nicholas W. Hughes","orcid":"https://orcid.org/0000-0001-9004-6288","observed_orcids":["https://orcid.org/0000-0001-9004-6288"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicholas W. Hughes","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9004-6288","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006535758","display_name":"Paloma A. Ruiz","orcid":"https://orcid.org/0000-0001-6208-5087","observed_orcids":["https://orcid.org/0000-0001-6208-5087"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paloma Ruiz","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6208-5087","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091700194","display_name":"Samuel H. Kim","orcid":"https://orcid.org/0000-0001-8353-6190","observed_orcids":["https://orcid.org/0000-0001-8353-6190"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Samuel H. Kim","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8353-6190","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026980998","display_name":"Emily G. Shuldiner","orcid":"https://orcid.org/0000-0002-5018-0500","observed_orcids":["https://orcid.org/0000-0002-5018-0500"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Emily G. Shuldiner","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5018-0500","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102788985","display_name":"Steven S. Lopez","orcid":"https://orcid.org/0009-0008-0926-0016","observed_orcids":["https://orcid.org/0009-0008-0926-0016"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven S. Lopez","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0008-0926-0016","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014446555","display_name":"Jess D. Hebert","orcid":"https://orcid.org/0000-0002-8778-5941","observed_orcids":["https://orcid.org/0000-0002-8778-5941"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jess D. Hebert","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8778-5941","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066886590","display_name":"Saswati Karmakar","orcid":"https://orcid.org/0000-0003-0315-5924","observed_orcids":["https://orcid.org/0000-0003-0315-5924"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Saswati Karmakar","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0315-5924","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000931609","display_name":"Laura Andrejka","orcid":"https://orcid.org/0000-0002-2202-5626","observed_orcids":["https://orcid.org/0000-0002-2202-5626"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Laura Andrejka","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2202-5626","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020838148","display_name":"Deniz Nesli Dolcen","orcid":"https://orcid.org/0000-0003-2441-7313","observed_orcids":["https://orcid.org/0000-0003-2441-7313"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Deniz Nesli Dolcen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2441-7313","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085003091","display_name":"G\u00e1bor Zolt\u00e1n Boross","orcid":"https://orcid.org/0000-0002-7208-5678","observed_orcids":["https://orcid.org/0000-0002-7208-5678"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gabor Boross","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7208-5678","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112905076","display_name":"Pauline Chu","orcid":"https://orcid.org/0000-0001-6561-6453","observed_orcids":["https://orcid.org/0000-0001-6561-6453"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pauline Chu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6561-6453","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067101935","display_name":"Christian A. Kunder","orcid":"https://orcid.org/0000-0003-1514-7550","observed_orcids":["https://orcid.org/0000-0003-1514-7550"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christian A. Kunder","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1514-7550","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098919249","display_name":"Colin R. Detrick","orcid":"https://orcid.org/0009-0002-4115-1668","observed_orcids":["https://orcid.org/0009-0002-4115-1668"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Colin Detrick","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0002-4115-1668","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014238634","display_name":"Sarah E. Pierce","orcid":"https://orcid.org/0000-0002-9145-9559","observed_orcids":["https://orcid.org/0000-0002-9145-9559"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sarah E. Pierce","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9145-9559","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027861576","display_name":"Emily L. Ashkin","orcid":"https://orcid.org/0000-0001-7363-7860","observed_orcids":["https://orcid.org/0000-0001-7363-7860"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Emily L. Ashkin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7363-7860","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066136174","display_name":"William James Greenleaf","orcid":"https://orcid.org/0000-0003-1409-3095","observed_orcids":["https://orcid.org/0000-0003-1409-3095"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William J. Greenleaf","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1409-3095","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050532805","display_name":"Anne Kathrin Voss","orcid":"https://orcid.org/0000-0002-3853-9381","observed_orcids":["https://orcid.org/0000-0002-3853-9381"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anne K. Voss","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3853-9381","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078083260","display_name":"Tim Thomas","orcid":"https://orcid.org/0000-0002-7623-8344","observed_orcids":["https://orcid.org/0000-0002-7623-8344"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tim Thomas","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7623-8344","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023048831","display_name":"Matt van de Rijn","orcid":"https://orcid.org/0000-0002-1909-9739","observed_orcids":["https://orcid.org/0000-0002-1909-9739"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matt van de Rijn","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1909-9739","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079594157","display_name":"Dmitri A. Petrov","orcid":"https://orcid.org/0000-0002-3664-9130","observed_orcids":["https://orcid.org/0000-0002-3664-9130"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dmitri A. Petrov","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3664-9130","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5062358716","display_name":"Monte M. Winslow","orcid":"https://orcid.org/0000-0002-5730-9573","observed_orcids":["https://orcid.org/0000-0002-5730-9573"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Monte M. Winslow","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5730-9573","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":0.4975999891757965,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":0.4975999891757965,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.4318999946117401,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.04360000044107437,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hbo1","display_name":"HBO1","score":0.8399999737739563},{"id":"https://openalex.org/keywords/mll1","display_name":"MLL1","score":0.9549999833106995},{"id":"https://openalex.org/keywords/tumor-suppression","display_name":"tumor suppression","score":0.8610000014305115},{"id":"https://openalex.org/keywords/gene-ontology-enrichment","display_name":"gene ontology enrichment","score":0.7839999794960022},{"id":"https://openalex.org/keywords/tumor-dependency","display_name":"tumor dependency","score":0.6650000214576721},{"id":"https://openalex.org/keywords/histone-methyltransferase-complex","display_name":"histone methyltransferase complex","score":0.5920000076293945}],"concepts":[{"id":"https://openalex.org/C121912465","wikidata":"https://www.wikidata.org/wiki/Q3589153","display_name":"Epigenomics","level":5,"score":0.8367999792098999},{"id":"https://openalex.org/C45235069","wikidata":"https://www.wikidata.org/wiki/Q278425","display_name":"Table (database)","level":2,"score":0.5532000064849854},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5507000088691711},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4900999963283539},{"id":"https://openalex.org/C19768560","wikidata":"https://www.wikidata.org/wiki/Q320727","display_name":"Dependency (UML)","level":2,"score":0.48170000314712524},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4503999948501587},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33009999990463257},{"id":"https://openalex.org/C179463898","wikidata":"https://www.wikidata.org/wiki/Q10273301","display_name":"Epigenesis","level":5,"score":0.29750001430511475},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.2840000092983246},{"id":"https://openalex.org/C117717151","wikidata":"https://www.wikidata.org/wiki/Q3589155","display_name":"Epigenome","level":5,"score":0.2786000072956085},{"id":"https://openalex.org/C179185449","wikidata":"https://www.wikidata.org/wiki/Q219699","display_name":"Suppressor","level":3,"score":0.27559998631477356},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.2522999942302704}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/2159-8290.30761408","doi":"https://doi.org/10.1158/2159-8290.30761408","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2159-8290.30761408","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/30761408","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Table_S6_from_Functional_Mapping_of_Epigenomic_Regulators_Uncovers_Coordinated_Tumor_Suppression_by_the_HBO1_and_MLL1_Complexes/30761408","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1158/2159-8290.30761408","doi":"https://doi.org/10.1158/2159-8290.30761408","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2159-8290.30761408","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4416900334","https://openalex.org/W4416900315","https://openalex.org/W4416900310","https://openalex.org/W4416900269","https://openalex.org/W4416900312","https://openalex.org/W4416900309","https://openalex.org/W4416900311","https://openalex.org/W4416900241","https://openalex.org/W4416900337","https://openalex.org/W4414532117"],"abstract_inverted_index":{"GO":[0],"enrichment":[1],"of":[2],"tumor":[3],"dependency":[4],"epigenomic":[5],"regulators":[6]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2025-12-02T00:00:00"}