{"id":"https://openalex.org/W4416735297","doi":"https://doi.org/10.1007/s40264-025-01636-4","title":"Prescription Drugs Subject to a Risk Evaluation and Mitigation Strategy: Patient Perspectives on Risk Communication and the Value of Educational Materials","display_name":"Prescription Drugs Subject to a Risk Evaluation and Mitigation Strategy: Patient Perspectives on Risk Communication and the Value of Educational Materials","publication_year":2025,"publication_date":"2025-11-27","ids":{"openalex":"https://openalex.org/W4416735297","doi":"https://doi.org/10.1007/s40264-025-01636-4","pmid":"https://pubmed.ncbi.nlm.nih.gov/41307831","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12973593"},"language":"en","primary_location":{"id":"doi:10.1007/s40264-025-01636-4","doi":"https://doi.org/10.1007/s40264-025-01636-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s40264-025-01636-4","pdf_url":null,"source":{"id":"https://openalex.org/S49488433","display_name":"Drug Safety","issn_l":"0114-5916","issn":["0114-5916","1179-1942"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Safety","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12973593/pdf/nihms-2127168.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000098024","display_name":"Susan C. Chimonas","orcid":"https://orcid.org/0000-0002-7742-5950","observed_orcids":["https://orcid.org/0000-0002-7742-5950"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Susan Chimonas","raw_affiliation_strings":["Center for Health Policy and Outcomes, Memorial Sloan Kettering Cancer Center, New York, NY, USA. chimonas@mskcc.org","Center for Health Policy and Outcomes, Memorial Sloan Kettering Cancer Center, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-7742-5950","affiliations":[{"raw_affiliation_string":"Center for Health Policy and Outcomes, Memorial Sloan Kettering Cancer Center, New York, NY, USA. chimonas@mskcc.org","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Center for Health Policy and Outcomes, Memorial Sloan Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085924518","display_name":"Carol A. Cosenza","orcid":"https://orcid.org/0000-0003-2948-024X","observed_orcids":["https://orcid.org/0000-0003-2948-024X"]},"institutions":[{"id":"https://openalex.org/I33434090","display_name":"University of Massachusetts Boston","ror":"https://ror.org/04ydmy275","country_code":"US","type":"education","lineage":["https://openalex.org/I33434090"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carol Cosenza","raw_affiliation_strings":["Center for Survey Research, University of Massachusetts Boston, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Survey Research, University of Massachusetts Boston, Boston, MA, USA","institution_ids":["https://openalex.org/I33434090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074257304","display_name":"Aaron Seth Kesselheim","orcid":"https://orcid.org/0000-0002-8867-2666","observed_orcids":["https://orcid.org/0000-0002-8867-2666"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron S. Kesselheim","raw_affiliation_strings":["Program On Regulation, Therapeutics, And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program On Regulation, Therapeutics, And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045378602","display_name":"Gita A. Toyserkani","orcid":"https://orcid.org/0000-0002-6946-6138","observed_orcids":["https://orcid.org/0000-0002-6946-6138"]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1333606569","display_name":"Center for Drug Evaluation and Research","ror":"https://ror.org/00yf3tm42","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1333606569"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gita A. Toyserkani","raw_affiliation_strings":["Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD, USA","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I1333606569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119947047","display_name":"Kate Heinrich Oswell","orcid":"https://orcid.org/0009-0004-8997-4756","observed_orcids":["https://orcid.org/0009-0004-8997-4756"]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1333606569","display_name":"Center for Drug Evaluation and Research","ror":"https://ror.org/00yf3tm42","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1333606569"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kate Heinrich Oswell","raw_affiliation_strings":["Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD, USA","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I1333606569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051761076","display_name":"Cynthia LaCivita","orcid":"https://orcid.org/0009-0001-8680-9008","observed_orcids":["https://orcid.org/0009-0001-8680-9008"]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1333606569","display_name":"Center for Drug Evaluation and Research","ror":"https://ror.org/00yf3tm42","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1333606569"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cynthia LaCivita","raw_affiliation_strings":["Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD, USA","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I1333606569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084218210","display_name":"Gerald J. Dal Pan","orcid":"https://orcid.org/0000-0003-4874-5864","observed_orcids":["https://orcid.org/0000-0003-4874-5864"]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1333606569","display_name":"Center for Drug Evaluation and Research","ror":"https://ror.org/00yf3tm42","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1333606569"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gerald J. Dal Pan","raw_affiliation_strings":["Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD, USA","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I1333606569"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035621209","display_name":"Ameet Sarpatwari","orcid":"https://orcid.org/0000-0001-5043-6206","observed_orcids":["https://orcid.org/0000-0001-5043-6206"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ameet Sarpatwari","raw_affiliation_strings":["Program On Regulation, Therapeutics, And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program On Regulation, Therapeutics, And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5000098024"],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":{"value":4990,"currency":"USD","value_usd":4990},"apc_paid":null,"fwci":2.5044,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.89969077,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"49","issue":"6","first_page":"667","last_page":"675"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10827","display_name":"Patient-Provider Communication in Healthcare","score":0.36719998717308044,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10827","display_name":"Patient-Provider Communication in Healthcare","score":0.36719998717308044,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13970","display_name":"Pharmacy and Medical Practices","score":0.2468000054359436,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.2362000048160553,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/risk-evaluation-and-mitigation-strategy","display_name":"risk evaluation and mitigation strategy","score":0.8629999756813049},{"id":"https://openalex.org/keywords/risk-communication","display_name":"risk communication","score":0.8090000152587891},{"id":"https://openalex.org/keywords/medication-guides","display_name":"medication guides","score":0.5889999866485596},{"id":"https://openalex.org/keywords/patient-and-caregiver-perspectives","display_name":"patient and caregiver perspectives","score":0.6159999966621399},{"id":"https://openalex.org/keywords/patient-preferences","display_name":"patient preferences","score":0.4000000059604645},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.37299999594688416},{"id":"https://openalex.org/keywords/patient-education-materials","display_name":"patient education materials","score":0.4350000023841858},{"id":"https://openalex.org/keywords/patient-empowerment","display_name":"patient empowerment","score":0.3889999985694885},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.5080000162124634},{"id":"https://openalex.org/keywords/alemtuzumab","display_name":"alemtuzumab","score":0.7229999899864197},{"id":"https://openalex.org/keywords/ambrisentan","display_name":"ambrisentan","score":0.9089999794960022},{"id":"https://openalex.org/keywords/clozapine","display_name":"clozapine","score":0.9869999885559082},{"id":"https://openalex.org/keywords/isotretinoin","display_name":"isotretinoin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/lenalidomide","display_name":"lenalidomide","score":1.0},{"id":"https://openalex.org/keywords/pegvaliase","display_name":"pegvaliase","score":0.9769999980926514},{"id":"https://openalex.org/keywords/pomalidomide","display_name":"pomalidomide","score":0.9980000257492065},{"id":"https://openalex.org/keywords/sodium-oxybate","display_name":"sodium oxybate","score":0.9980000257492065}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8756999969482422},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.6611999869346619},{"id":"https://openalex.org/C2776291640","wikidata":"https://www.wikidata.org/wiki/Q2912517","display_name":"Value (mathematics)","level":2,"score":0.5845000147819519},{"id":"https://openalex.org/C2777855551","wikidata":"https://www.wikidata.org/wiki/Q12310021","display_name":"Subject (documents)","level":2,"score":0.5321999788284302},{"id":"https://openalex.org/C12174686","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk assessment","level":2,"score":0.5266000032424927},{"id":"https://openalex.org/C3017634809","wikidata":"https://www.wikidata.org/wiki/Q84862664","display_name":"Risk communication","level":2,"score":0.4496000111103058},{"id":"https://openalex.org/C509550671","wikidata":"https://www.wikidata.org/wiki/Q126945","display_name":"Medical education","level":1,"score":0.3952000141143799},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.36480000615119934},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.35409998893737793},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.3531000018119812},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.3465000092983246},{"id":"https://openalex.org/C32896092","wikidata":"https://www.wikidata.org/wiki/Q189447","display_name":"Risk management","level":2,"score":0.31360000371932983},{"id":"https://openalex.org/C2777929519","wikidata":"https://www.wikidata.org/wiki/Q7144988","display_name":"Patient education","level":2,"score":0.3077999949455261},{"id":"https://openalex.org/C2910723583","wikidata":"https://www.wikidata.org/wiki/Q65066344","display_name":"Drug Utilization Review","level":3,"score":0.302700012922287},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.2953999936580658},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.2921000123023987},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.2892000079154968},{"id":"https://openalex.org/C2779328685","wikidata":"https://www.wikidata.org/wiki/Q1475557","display_name":"Patient safety","level":3,"score":0.2833999991416931},{"id":"https://openalex.org/C2778858636","wikidata":"https://www.wikidata.org/wiki/Q1643563","display_name":"Prescription drug","level":3,"score":0.26600000262260437},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.2563999891281128},{"id":"https://openalex.org/C55587333","wikidata":"https://www.wikidata.org/wiki/Q1133029","display_name":"Engineering ethics","level":1,"score":0.2563000023365021}],"mesh":[{"descriptor_ui":"D000073938","descriptor_name":"Risk Evaluation and Mitigation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003142","descriptor_name":"Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010353","descriptor_name":"Patient Education as Topic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014486","descriptor_name":"United States Food and Drug Administration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017028","descriptor_name":"Caregivers","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055553","descriptor_name":"Prescription Drugs","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s40264-025-01636-4","doi":"https://doi.org/10.1007/s40264-025-01636-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s40264-025-01636-4","pdf_url":null,"source":{"id":"https://openalex.org/S49488433","display_name":"Drug Safety","issn_l":"0114-5916","issn":["0114-5916","1179-1942"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Safety","raw_type":"journal-article"},{"id":"pmid:41307831","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41307831","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug safety","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12973593","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41307831/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12973593/pdf/nihms-2127168.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Drug Saf","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12973593","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41307831/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12973593/pdf/nihms-2127168.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Drug Saf","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2746318747","display_name":null,"funder_award_id":"75F40120C0044","funder_id":"https://openalex.org/F4320332163","funder_display_name":"U.S. Food and Drug Administration"},{"id":"https://openalex.org/G3050811832","display_name":null,"funder_award_id":"FD999999","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7237167005","display_name":null,"funder_award_id":"75F40120C0044","funder_id":"https://openalex.org/F5190423519","funder_display_name":"Center for Drug Evaluation and Research"},{"id":"https://openalex.org/G9000856728","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA008748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320308349","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78"},{"id":"https://openalex.org/F4320313188","display_name":"University of Massachusetts Boston","ror":"https://ror.org/04ydmy275"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332163","display_name":"U.S. Food and Drug Administration","ror":"https://ror.org/034xvzb47"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F5190423519","display_name":"Center for Drug Evaluation and Research","ror":"https://ror.org/00yf3tm42"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4416735297.pdf","grobid_xml":"https://content.openalex.org/works/W4416735297.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1565829228","https://openalex.org/W1586786051","https://openalex.org/W1651004015","https://openalex.org/W2038550900","https://openalex.org/W2067220183","https://openalex.org/W2079659616","https://openalex.org/W2129660502","https://openalex.org/W2135795051","https://openalex.org/W2138664283","https://openalex.org/W2142225512","https://openalex.org/W2159776611","https://openalex.org/W2399972698","https://openalex.org/W2524597629","https://openalex.org/W2569346365","https://openalex.org/W2588199046","https://openalex.org/W2790641443","https://openalex.org/W2891155826","https://openalex.org/W2917106663","https://openalex.org/W3125467590","https://openalex.org/W3132546423","https://openalex.org/W3158677318","https://openalex.org/W3174141738","https://openalex.org/W4206521392","https://openalex.org/W4243000071","https://openalex.org/W4403793942"],"related_works":["https://openalex.org/W7213764250","https://openalex.org/W4206521392","https://openalex.org/W4415059984","https://openalex.org/W7206173927","https://openalex.org/W4391969002","https://openalex.org/W2883557017","https://openalex.org/W3158677318","https://openalex.org/W1586786051","https://openalex.org/W7097347360","https://openalex.org/W4390667082"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-11-28T00:00:00"}