{"id":"https://openalex.org/W4416729220","doi":"https://doi.org/10.3389/fphar.2025.1680647","title":"Efficacy and safety of Centella asiatica (L.) Urb. [Apiaceae] as a dietary supplement for glycemic control and lipid regulation in patients with type 2 diabetes: a randomized controlled trial in Thailand","display_name":"Efficacy and safety of Centella asiatica (L.) Urb. [Apiaceae] as a dietary supplement for glycemic control and lipid regulation in patients with type 2 diabetes: a randomized controlled trial in Thailand","publication_year":2025,"publication_date":"2025-11-26","ids":{"openalex":"https://openalex.org/W4416729220","doi":"https://doi.org/10.3389/fphar.2025.1680647","pmid":"https://pubmed.ncbi.nlm.nih.gov/41383475","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12689944"},"language":"en","primary_location":{"id":"doi:10.3389/fphar.2025.1680647","doi":"https://doi.org/10.3389/fphar.2025.1680647","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphar.2025.1680647","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1680647/pdf","source":{"id":"https://openalex.org/S132108250","display_name":"Frontiers in Pharmacology","issn_l":"1663-9812","issn":["1663-9812"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://public-pages-files-2025.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1680647/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016498820","display_name":"Weeratian Tawanwongsri","orcid":"https://orcid.org/0000-0002-1949-7323","observed_orcids":["https://orcid.org/0000-0002-1949-7323"]},"institutions":[{"id":"https://openalex.org/I96916377","display_name":"Walailak University","ror":"https://ror.org/04b69g067","country_code":"TH","type":"education","lineage":["https://openalex.org/I96916377"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Weeratian Tawanwongsri","raw_affiliation_strings":["Center of Excellence in Data Science for Health Study, Walailak University, Nakhon Si Thammarat, Thailand","Department of Internal Medicine, Division of Dermatology, School of Medicine, Walailak University, Nakhon Si Thammarat, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Excellence in Data Science for Health Study, Walailak University, Nakhon Si Thammarat, Thailand","institution_ids":["https://openalex.org/I96916377"]},{"raw_affiliation_string":"Department of Internal Medicine, Division of Dermatology, School of Medicine, Walailak University, Nakhon Si Thammarat, Thailand","institution_ids":["https://openalex.org/I96916377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050293359","display_name":"Auemphon Mordmuang","orcid":"https://orcid.org/0000-0002-3979-9599","observed_orcids":["https://orcid.org/0000-0002-3979-9599"]},"institutions":[{"id":"https://openalex.org/I96916377","display_name":"Walailak University","ror":"https://ror.org/04b69g067","country_code":"TH","type":"education","lineage":["https://openalex.org/I96916377"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Auemphon Mordmuang","raw_affiliation_strings":["Department of Medical Sciences, School of Medicine, Walailak University, Nakhon Si Thammarat, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Sciences, School of Medicine, Walailak University, Nakhon Si Thammarat, Thailand","institution_ids":["https://openalex.org/I96916377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085803386","display_name":"Tharin Phenwan","orcid":"https://orcid.org/0000-0003-0120-952X","observed_orcids":["https://orcid.org/0000-0003-0120-952X"]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tharin Phenwan","raw_affiliation_strings":["School of Health Sciences, University of Dundee, Dundee, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Health Sciences, University of Dundee, Dundee, United Kingdom","institution_ids":["https://openalex.org/I177639307"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5092274187","display_name":"Doungkamol Siri-Archawawat","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I96916377","display_name":"Walailak University","ror":"https://ror.org/04b69g067","country_code":"TH","type":"education","lineage":["https://openalex.org/I96916377"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Doungkamol Siri-archawawat","raw_affiliation_strings":["Department of Internal Medicine, Division of Neurology, School of Medicine, Walailak University, Nakhon Si Thammarat, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Division of Neurology, School of Medicine, Walailak University, Nakhon Si Thammarat, Thailand","institution_ids":["https://openalex.org/I96916377"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5092274187"],"corresponding_institution_ids":["https://openalex.org/I96916377"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":2.035,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.85820852,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"16","issue":null,"first_page":"1680647","last_page":"1680647"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9375,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9375,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12891","display_name":"Medicinal Plants and Neuroprotection","score":0.041099999099969864,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13828","display_name":"Natural Products and Biological Research","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/centella-asiatica","display_name":"Centella asiatica","score":1.0},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9750000238418579},{"id":"https://openalex.org/keywords/dietary-supplements","display_name":"dietary supplements","score":0.9490000009536743},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.9819999933242798},{"id":"https://openalex.org/keywords/lipid-regulation","display_name":"lipid regulation","score":0.902999997138977},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.8679999709129333},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.8029999732971191},{"id":"https://openalex.org/keywords/fasting-blood-glucose","display_name":"fasting blood glucose","score":0.9800000190734863},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.7049999833106995},{"id":"https://openalex.org/keywords/gastrointestinal-symptoms","display_name":"gastrointestinal symptoms","score":0.6620000004768372},{"id":"https://openalex.org/keywords/complementary-therapy","display_name":"complementary therapy","score":0.515999972820282}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8550999760627747},{"id":"https://openalex.org/C2780473172","wikidata":"https://www.wikidata.org/wiki/Q5572518","display_name":"Glycemic","level":3,"score":0.6899999976158142},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6690000295639038},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.65829998254776},{"id":"https://openalex.org/C2779077069","wikidata":"https://www.wikidata.org/wiki/Q1348880","display_name":"Centella","level":2,"score":0.6545000076293945},{"id":"https://openalex.org/C3018363719","wikidata":"https://www.wikidata.org/wiki/Q645858","display_name":"Dietary supplement","level":2,"score":0.6524999737739563},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5889000296592712},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.43619999289512634},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.43380001187324524},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.3977999985218048},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.38999998569488525},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.36480000615119934},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.3264999985694885},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.28760001063346863},{"id":"https://openalex.org/C148257392","wikidata":"https://www.wikidata.org/wiki/Q2358629","display_name":"Clinical nutrition","level":2,"score":0.2842999994754791},{"id":"https://openalex.org/C3019569299","wikidata":"https://www.wikidata.org/wiki/Q645858","display_name":"Food supplement","level":2,"score":0.27970001101493835},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.2574999928474426},{"id":"https://openalex.org/C17857428","wikidata":"https://www.wikidata.org/wiki/Q533025","display_name":"Nutraceutical","level":2,"score":0.25619998574256897},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.2549000084400177}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fphar.2025.1680647","doi":"https://doi.org/10.3389/fphar.2025.1680647","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphar.2025.1680647","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1680647/pdf","source":{"id":"https://openalex.org/S132108250","display_name":"Frontiers in Pharmacology","issn_l":"1663-9812","issn":["1663-9812"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pharmacology","raw_type":"journal-article"},{"id":"pmid:41383475","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41383475","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in pharmacology","raw_type":"Clinical Trial"},{"id":"pmh:oai:discovery.dundee.ac.uk:openaire/63262188-546c-4fbc-9ef0-8345f0c92b67","doi":null,"is_oa":true,"landing_page_url":"https://discovery.dundee.ac.uk/en/publications/63262188-546c-4fbc-9ef0-8345f0c92b67","pdf_url":null,"source":{"id":"https://openalex.org/S4306400523","display_name":"Discovery Research Portal (University of Dundee)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177639307","host_organization_name":"University of Dundee","host_organization_lineage":["https://openalex.org/I177639307"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tawanwongsri, W, Mordmuang, A, Phenwan, T & Siri-archawawat, D 2025, 'Efficacy and safety of Centella asiatica (L.) Urb. [Apiaceae] as a dietary supplement for glycemic control and lipid regulation in patients with type 2 diabetes : a randomized controlled trial in Thailand', Frontiers in Pharmacology, vol. 16, 1680647. https://doi.org/10.3389/fphar.2025.1680647","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12689944","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12689944/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Pharmacol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:3b947bd3b8a74629aa741d32265d16cd","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/3b947bd3b8a74629aa741d32265d16cd","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Pharmacology, Vol 16 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fphar.2025.1680647","doi":"https://doi.org/10.3389/fphar.2025.1680647","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphar.2025.1680647","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1680647/pdf","source":{"id":"https://openalex.org/S132108250","display_name":"Frontiers in Pharmacology","issn_l":"1663-9812","issn":["1663-9812"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pharmacology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4416729220.pdf","grobid_xml":"https://content.openalex.org/works/W4416729220.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1976886448","https://openalex.org/W1982034871","https://openalex.org/W2005775898","https://openalex.org/W2072500831","https://openalex.org/W2146901298","https://openalex.org/W2159964692","https://openalex.org/W2163693320","https://openalex.org/W2182689614","https://openalex.org/W2418828468","https://openalex.org/W2471485099","https://openalex.org/W2606077643","https://openalex.org/W2746634516","https://openalex.org/W2759911350","https://openalex.org/W2763916821","https://openalex.org/W2802940337","https://openalex.org/W2914758292","https://openalex.org/W2920672907","https://openalex.org/W2972869264","https://openalex.org/W2999598292","https://openalex.org/W3018703876","https://openalex.org/W3080167032","https://openalex.org/W3082557756","https://openalex.org/W3083682345","https://openalex.org/W3090746759","https://openalex.org/W3132900806","https://openalex.org/W3155873373","https://openalex.org/W3193652841","https://openalex.org/W3196213304","https://openalex.org/W3198391374","https://openalex.org/W4214715117","https://openalex.org/W4295346553","https://openalex.org/W4311264067","https://openalex.org/W4376647457","https://openalex.org/W4383186445","https://openalex.org/W4384926031","https://openalex.org/W4386091311","https://openalex.org/W4387600372","https://openalex.org/W4389522735","https://openalex.org/W4389565729","https://openalex.org/W4393076766","https://openalex.org/W4399847980","https://openalex.org/W4412465953","https://openalex.org/W7116960313"],"related_works":["https://openalex.org/W7215031222","https://openalex.org/W4405840698","https://openalex.org/W7096012932","https://openalex.org/W2969259825","https://openalex.org/W2181711695","https://openalex.org/W2275528140","https://openalex.org/W7166655202","https://openalex.org/W3080167032","https://openalex.org/W3194852061","https://openalex.org/W2047913422"],"abstract_inverted_index":{"Purpose:":[0],"(L.)":[1],"Urb.":[2],"[Apiaceae]":[3],"(CA)":[4,25],"as":[5],"a":[6,172],"complementary":[7],"dietary":[8],"supplement":[9],"for":[10,32,107],"glycemic":[11,176],"and":[12,23,52,112,191],"lipid":[13,146,178],"control":[14],"in":[15,92,100,120,131,175],"patients":[16],"with":[17,76,185,208],"type":[18],"2":[19],"diabetes":[20,110],"mellitus.":[21],"Patients":[22],"methods:":[24],"extract":[26],"1,200":[27],"mg/day":[28],"or":[29,125,177],"matched":[30],"placebo":[31,65],"6":[33,86],"months.":[34],"The":[35],"primary":[36],"outcome":[37],"was":[38,71,94,139,151,166,206],"glycated":[39],"hemoglobin":[40],"(HbA1c).":[41],"Secondary":[42],"outcomes":[43,179],"were":[44,116,133,158],"fasting":[45,122],"plasma":[46,123],"glucose,":[47,124],"low-density":[48],"lipoprotein":[49],"cholesterol":[50],"(LDL-C),":[51],"adverse":[53],"events.":[54],"Results:":[55],"Seventy":[56],"participants":[57],"completed":[58],"the":[59,101,135,209],"trial":[60,205],"(CA":[61,82],"n":[62,66],"=":[63,67,97,143],"34;":[64],"36).":[68],"Median":[69],"age":[70],"57":[72],"vs.":[73,80,83],"60":[74],"years,":[75],"women":[77],"comprising":[78],"55.9%":[79],"41.7%":[81],"placebo).":[84],"At":[85],"months,":[87],"an":[88],"unadjusted":[89],"between-group":[90,118,137],"difference":[91],"HbA1c":[93],"observed":[95],"(p":[96,142],"0.006);":[98],"however,":[99],"prespecified":[102],"adjusted":[103,136],"analysis":[104],"(ANCOVA":[105],"controlling":[106],"baseline":[108],"HbA1c,":[109,121],"duration,":[111],"sulfonylurea":[113],"use)":[114],"there":[115],"no":[117],"differences":[119],"LDL-C.":[126],"Although":[127],"small":[128],"within-group":[129],"reductions":[130],"LDL-C":[132],"noted,":[134],"comparison":[138],"not":[140,170],"significant":[141,173],"0.536),":[144],"so":[145],"findings":[147],"are":[148,194],"exploratory.":[149],"CA":[150,164],"well":[152],"tolerated;":[153],"mild,":[154],"transient":[155],"gastrointestinal":[156],"symptoms":[157],"most":[159],"common":[160],"(5/34,":[161],"14.7%).":[162],"Conclusion:":[163],"supplementation":[165],"safe":[167],"but":[168],"did":[169],"produce":[171],"change":[174],"compared":[180],"to":[181,196],"placebo.":[182],"Further":[183],"studies":[184],"larger":[186],"sample":[187],"sizes,":[188],"longer":[189],"durations,":[190],"higher":[192],"doses":[193],"warranted":[195],"verify":[197],"potential":[198],"metabolic":[199],"effects.":[200],"Clinical":[201,211],"Trial":[202],"Registration:":[203],"This":[204],"registered":[207],"Thai":[210],"Trials":[212],"Registry":[213],"(TCTR20221219003);":[214],"https://www.thaiclinicaltrials.org/show/TCTR20221219003.":[215]},"counts_by_year":[{"year":2026,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2025-11-27T00:00:00"}
