{"id":"https://openalex.org/W4416721572","doi":"https://doi.org/10.1158/2326-6066.30720672","title":"Supplementary Data from Radiofrequency Ablation Remodels the Tumor Microenvironment and Promotes Neutrophil-Mediated Abscopal Immunomodulation in Pancreatic Cancer","display_name":"Supplementary Data from Radiofrequency Ablation Remodels the Tumor Microenvironment and Promotes Neutrophil-Mediated Abscopal Immunomodulation in Pancreatic Cancer","publication_year":2025,"publication_date":"2025-11-26","ids":{"openalex":"https://openalex.org/W4416721572","doi":"https://doi.org/10.1158/2326-6066.30720672"},"language":"en","primary_location":{"id":"doi:10.1158/2326-6066.30720672","doi":"https://doi.org/10.1158/2326-6066.30720672","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2326-6066.30720672","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/2326-6066.30720672","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022792492","display_name":"Erika Yanil Faraoni","orcid":"https://orcid.org/0000-0003-0731-2122","observed_orcids":["https://orcid.org/0000-0003-0731-2122"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Erika Y. Faraoni","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0731-2122","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044451229","display_name":"Baylee J. O\u2019Brien","orcid":"https://orcid.org/0000-0003-4272-6654","observed_orcids":["https://orcid.org/0000-0003-4272-6654"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Baylee J. O'Brien","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4272-6654","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036906585","display_name":"Lincoln N. Strickland","orcid":"https://orcid.org/0000-0002-2347-4431","observed_orcids":["https://orcid.org/0000-0002-2347-4431"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lincoln N. Strickland","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2347-4431","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055240390","display_name":"Baron K. Osborn","orcid":"https://orcid.org/0000-0001-9333-5181","observed_orcids":["https://orcid.org/0000-0001-9333-5181"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Baron K. Osborn","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9333-5181","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023411373","display_name":"Victoria Mota","orcid":"https://orcid.org/0000-0002-9820-5092","observed_orcids":["https://orcid.org/0000-0002-9820-5092"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Victoria Mota","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9820-5092","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076861087","display_name":"Jarod Chaney","orcid":"https://orcid.org/0000-0001-5933-8792","observed_orcids":["https://orcid.org/0000-0001-5933-8792"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jarod Chaney","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5933-8792","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021020740","display_name":"Constance Lynn Atkins","orcid":"https://orcid.org/0000-0002-0428-1319","observed_orcids":["https://orcid.org/0000-0002-0428-1319"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Constance Lynn Atkins","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0428-1319","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004135808","display_name":"Putao Cen","orcid":"https://orcid.org/0000-0001-5633-311X","observed_orcids":["https://orcid.org/0000-0001-5633-311X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Putao Cen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5633-311X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067789137","display_name":"Julie Haewon Rowe","orcid":"https://orcid.org/0000-0001-7583-7794","observed_orcids":["https://orcid.org/0000-0001-7583-7794"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julie Rowe","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7583-7794","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026987725","display_name":"Jessica C. Cardenas","orcid":"https://orcid.org/0000-0001-6668-1054","observed_orcids":["https://orcid.org/0000-0001-6668-1054"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jessica Cardenas","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6668-1054","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050242237","display_name":"Kyle L. Poulsen","orcid":"https://orcid.org/0000-0003-3218-8418","observed_orcids":["https://orcid.org/0000-0003-3218-8418"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kyle L. Poulsen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3218-8418","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012684884","display_name":"Curtis Jackson Wray","orcid":"https://orcid.org/0000-0003-4425-4566","observed_orcids":["https://orcid.org/0000-0003-4425-4566"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Curtis J. Wray","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4425-4566","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008651395","display_name":"Nirav C Thosani","orcid":"https://orcid.org/0000-0002-4607-6241","observed_orcids":["https://orcid.org/0000-0002-4607-6241"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nirav C. Thosani","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4607-6241","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5000636834","display_name":"Jennifer M. Bailey","orcid":"https://orcid.org/0000-0002-4750-106X","observed_orcids":["https://orcid.org/0000-0002-4750-106X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jennifer M. Bailey-Lundberg","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4750-106X","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.8895999789237976,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.8895999789237976,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.07760000228881836,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiofrequency-ablation","display_name":"radiofrequency ablation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tumor-microenvironment-remodeling","display_name":"tumor microenvironment remodeling","score":0.8349999785423279},{"id":"https://openalex.org/keywords/neutrophils","display_name":"neutrophils","score":0.9110000133514404},{"id":"https://openalex.org/keywords/abscopal-effect","display_name":"abscopal effect","score":0.9670000076293945},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.972000002861023},{"id":"https://openalex.org/keywords/pancreatic-cancer","display_name":"pancreatic cancer","score":0.8019999861717224},{"id":"https://openalex.org/keywords/tumor-immunology","display_name":"tumor immunology","score":0.5299999713897705}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7243000268936157},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.7109000086784363},{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.6906999945640564},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5324000120162964},{"id":"https://openalex.org/C2777377203","wikidata":"https://www.wikidata.org/wiki/Q1809554","display_name":"Radiofrequency ablation","level":3,"score":0.5278000235557556},{"id":"https://openalex.org/C2781274730","wikidata":"https://www.wikidata.org/wiki/Q4669679","display_name":"Abscopal effect","level":4,"score":0.40400001406669617},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.3610000014305115},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.31150001287460327},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2964000105857849},{"id":"https://openalex.org/C2778902805","wikidata":"https://www.wikidata.org/wiki/Q322177","display_name":"Ablation","level":2,"score":0.2808000147342682},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.26980000734329224},{"id":"https://openalex.org/C2777996000","wikidata":"https://www.wikidata.org/wiki/Q7130412","display_name":"Pancreatic tumor","level":4,"score":0.2662000060081482},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.25529998540878296}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/2326-6066.30720672","doi":"https://doi.org/10.1158/2326-6066.30720672","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2326-6066.30720672","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/30720672","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Data_from_Radiofrequency_Ablation_Remodels_the_Tumor_Microenvironment_and_Promotes_Neutrophil-Mediated_Abscopal_Immunomodulation_in_Pancreatic_Cancer/30720672","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/2326-6066.30720672","doi":"https://doi.org/10.1158/2326-6066.30720672","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2326-6066.30720672","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4308834800","https://openalex.org/W4362547331","https://openalex.org/W4205228505","https://openalex.org/W2336650486","https://openalex.org/W2757828780","https://openalex.org/W7038345240","https://openalex.org/W3131039777","https://openalex.org/W4404635574","https://openalex.org/W2791466252","https://openalex.org/W7152118826"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2025-11-27T00:00:00"}