{"id":"https://openalex.org/W4416713480","doi":"https://doi.org/10.1016/j.cmi.2025.11.018","title":"Next-generation sequencing improves detection of anaerobic and polymicrobial infections in pyogenic liver abscess","display_name":"Next-generation sequencing improves detection of anaerobic and polymicrobial infections in pyogenic liver abscess","publication_year":2025,"publication_date":"2025-11-27","ids":{"openalex":"https://openalex.org/W4416713480","doi":"https://doi.org/10.1016/j.cmi.2025.11.018","pmid":"https://pubmed.ncbi.nlm.nih.gov/41314605"},"language":"en","primary_location":{"id":"doi:10.1016/j.cmi.2025.11.018","doi":"https://doi.org/10.1016/j.cmi.2025.11.018","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cmi.2025.11.018","pdf_url":null,"source":{"id":"https://openalex.org/S71414007","display_name":"Clinical Microbiology and Infection","issn_l":"1198-743X","issn":["1198-743X","1469-0691"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Microbiology and Infection","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101940902","display_name":"Ju Sun Song","orcid":"https://orcid.org/0000-0003-4607-872X","observed_orcids":["https://orcid.org/0000-0003-4607-872X"]},"institutions":[{"id":"https://openalex.org/I4402554165","display_name":"Green Cross Laboratories (South Korea)","ror":"https://ror.org/01znbx673","country_code":"KR","type":"company","lineage":["https://openalex.org/I4402554165"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ju Sun Song","raw_affiliation_strings":["GC Genome, Department of Laboratory Medicine, Green Cross Laboratories, Yonginsi, Republic of Korea","GC Genome, Department of Laboratory Medicine, Green Cross Laboratories"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GC Genome, Department of Laboratory Medicine, Green Cross Laboratories, Yonginsi, Republic of Korea","institution_ids":["https://openalex.org/I4402554165"]},{"raw_affiliation_string":"GC Genome, Department of Laboratory Medicine, Green Cross Laboratories","institution_ids":["https://openalex.org/I4402554165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088902130","display_name":"Young Kul Jung","orcid":"https://orcid.org/0000-0002-6566-1382","observed_orcids":["https://orcid.org/0000-0002-6566-1382"]},"institutions":[{"id":"https://openalex.org/I4405261856","display_name":"Korea University Ansan Hospital","ror":"https://ror.org/05yp5js06","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I197347611","https://openalex.org/I2799980853","https://openalex.org/I4405261856"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Young Kul Jung","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansansi, Republic of Korea","Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansansi, Republic of Korea","institution_ids":["https://openalex.org/I4405261856"]},{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital","institution_ids":["https://openalex.org/I4405261856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037119368","display_name":"Solbi Kweon","orcid":"https://orcid.org/0000-0002-8021-9605","observed_orcids":["https://orcid.org/0000-0002-8021-9605"]},"institutions":[{"id":"https://openalex.org/I4402554165","display_name":"Green Cross Laboratories (South Korea)","ror":"https://ror.org/01znbx673","country_code":"KR","type":"company","lineage":["https://openalex.org/I4402554165"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Solbi Kweon","raw_affiliation_strings":["GC Genome, Department of Laboratory Medicine, Green Cross Laboratories, Yonginsi, Republic of Korea","GC Genome, Department of Laboratory Medicine, Green Cross Laboratories"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GC Genome, Department of Laboratory Medicine, Green Cross Laboratories, Yonginsi, Republic of Korea","institution_ids":["https://openalex.org/I4402554165"]},{"raw_affiliation_string":"GC Genome, Department of Laboratory Medicine, Green Cross Laboratories","institution_ids":["https://openalex.org/I4402554165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041387893","display_name":"Seong-Hee Kang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405261856","display_name":"Korea University Ansan Hospital","ror":"https://ror.org/05yp5js06","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I197347611","https://openalex.org/I2799980853","https://openalex.org/I4405261856"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seong-Hee Kang","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansansi, Republic of Korea","Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansansi, Republic of Korea","institution_ids":["https://openalex.org/I4405261856"]},{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital","institution_ids":["https://openalex.org/I4405261856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100745130","display_name":"Min Jae Kim","orcid":"https://orcid.org/0000-0002-5489-8608","observed_orcids":["https://orcid.org/0000-0002-5489-8608"]},"institutions":[{"id":"https://openalex.org/I2801680663","display_name":"Asan Medical Center","ror":"https://ror.org/03s5q0090","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2801680663","https://openalex.org/I4210167194"]},{"id":"https://openalex.org/I40542001","display_name":"University of Ulsan","ror":"https://ror.org/02c2f8975","country_code":"KR","type":"education","lineage":["https://openalex.org/I40542001"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Min Jae Kim","raw_affiliation_strings":["Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea","Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine. Electronic address: nahani99@gmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I2801680663","https://openalex.org/I40542001"]},{"raw_affiliation_string":"Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine. Electronic address: nahani99@gmail.com","institution_ids":["https://openalex.org/I2801680663","https://openalex.org/I40542001"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072844970","display_name":"Jeong\u2010Ju Yoo","orcid":"https://orcid.org/0000-0002-7802-0381","observed_orcids":["https://orcid.org/0000-0002-7802-0381"]},"institutions":[{"id":"https://openalex.org/I4405256198","display_name":"Soonchunhyang University Hospital Bucheon","ror":"https://ror.org/03wg7b808","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4405256198"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jeong-Ju Yoo","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheonsi, Republic of Korea. Electronic address: puby17@naver.com","Division of Gastroenterology and Hepatology, Department of internal medicine, Soonchunhyang University Bucheon Hospital. Electronic address: puby17@naver.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheonsi, Republic of Korea. Electronic address: puby17@naver.com","institution_ids":["https://openalex.org/I4405256198"]},{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Department of internal medicine, Soonchunhyang University Bucheon Hospital. Electronic address: puby17@naver.com","institution_ids":["https://openalex.org/I4405256198"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5072844970","https://openalex.org/A5100745130"],"corresponding_institution_ids":["https://openalex.org/I2801680663","https://openalex.org/I40542001","https://openalex.org/I4405256198"],"apc_list":{"value":3780,"currency":"USD","value_usd":3780},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"3","first_page":"498","last_page":"500"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12463","display_name":"Amoebic Infections and Treatments","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12463","display_name":"Amoebic Infections and Treatments","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.008700000122189522,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12824","display_name":"Infections and bacterial resistance","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pyogenic-liver-abscess","display_name":"pyogenic liver abscess","score":1.0},{"id":"https://openalex.org/keywords/anaerobic-bacteria","display_name":"anaerobic bacteria","score":0.8510000109672546},{"id":"https://openalex.org/keywords/coinfection","display_name":"co-infection","score":0.8539999723434448},{"id":"https://openalex.org/keywords/klebsiella-pneumoniae","display_name":"Klebsiella pneumoniae","score":0.9800000190734863},{"id":"https://openalex.org/keywords/next-generation-sequencing","display_name":"next-generation sequencing","score":0.7419999837875366},{"id":"https://openalex.org/keywords/microbial-diversity","display_name":"microbial diversity","score":0.6539999842643738},{"id":"https://openalex.org/keywords/empirical-antibiotic-therapy","display_name":"empirical antibiotic therapy","score":0.7889999747276306},{"id":"https://openalex.org/keywords/pathogen-detection","display_name":"pathogen detection","score":0.44699999690055847}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7123000025749207},{"id":"https://openalex.org/C5140985","wikidata":"https://www.wikidata.org/wiki/Q483866","display_name":"Anaerobic exercise","level":2,"score":0.6898000240325928},{"id":"https://openalex.org/C2779165098","wikidata":"https://www.wikidata.org/wiki/Q7263138","display_name":"Pyogenic liver abscess","level":4,"score":0.6118000149726868},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5188999772071838},{"id":"https://openalex.org/C2779690883","wikidata":"https://www.wikidata.org/wiki/Q1811092","display_name":"Liver abscess","level":3,"score":0.45190000534057617},{"id":"https://openalex.org/C2992397963","wikidata":"https://www.wikidata.org/wiki/Q189790","display_name":"Anaerobic bacteria","level":3,"score":0.39980000257492065},{"id":"https://openalex.org/C2909981330","wikidata":"https://www.wikidata.org/wiki/Q857288","display_name":"Gram-positive bacterial infections","level":3,"score":0.3919999897480011},{"id":"https://openalex.org/C2908810495","wikidata":"https://www.wikidata.org/wiki/Q327663","display_name":"Clostridium Infections","level":4,"score":0.367900013923645},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34950000047683716},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3384999930858612},{"id":"https://openalex.org/C2778663903","wikidata":"https://www.wikidata.org/wiki/Q140018","display_name":"Streptococcaceae","level":3,"score":0.3239000141620636},{"id":"https://openalex.org/C2777035434","wikidata":"https://www.wikidata.org/wiki/Q164655","display_name":"Abscess","level":2,"score":0.3075999915599823},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.30480000376701355},{"id":"https://openalex.org/C2779443120","wikidata":"https://www.wikidata.org/wiki/Q650912","display_name":"Bacteremia","level":3,"score":0.30469998717308044},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.2630000114440918},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.25999999046325684},{"id":"https://openalex.org/C2780246119","wikidata":"https://www.wikidata.org/wiki/Q221817","display_name":"Bacteroides fragilis","level":3,"score":0.2565999925136566},{"id":"https://openalex.org/C2911159362","wikidata":"https://www.wikidata.org/wiki/Q190161","display_name":"STREPTOCOCCAL INFECTIONS","level":2,"score":0.2533000111579895}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.cmi.2025.11.018","doi":"https://doi.org/10.1016/j.cmi.2025.11.018","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cmi.2025.11.018","pdf_url":null,"source":{"id":"https://openalex.org/S71414007","display_name":"Clinical Microbiology and Infection","issn_l":"1198-743X","issn":["1198-743X","1469-0691"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Microbiology and Infection","raw_type":"journal-article"},{"id":"pmid:41314605","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41314605","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases","raw_type":"Letter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321301","display_name":"Soonchunhyang University","ror":"https://ror.org/03qjsrb10"},{"id":"https://openalex.org/F4320329389","display_name":"Korean Association for the Study of the Liver","ror":"https://ror.org/03jtbjn48"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W2084691704","https://openalex.org/W2893361332","https://openalex.org/W3194683009","https://openalex.org/W4220908583"],"related_works":["https://openalex.org/W7129072578","https://openalex.org/W4406246603","https://openalex.org/W2754794257","https://openalex.org/W2083428043","https://openalex.org/W4409800148","https://openalex.org/W4220908583","https://openalex.org/W2471887247","https://openalex.org/W4320915071","https://openalex.org/W3081520301","https://openalex.org/W2560361277"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2025-11-28T00:00:00"}