{"id":"https://openalex.org/W4416701713","doi":"https://doi.org/10.1016/j.crmeth.2025.101242","title":"Visual detection of seizures in mice using supervised machine learning","display_name":"Visual detection of seizures in mice using supervised machine learning","publication_year":2025,"publication_date":"2025-11-26","ids":{"openalex":"https://openalex.org/W4416701713","doi":"https://doi.org/10.1016/j.crmeth.2025.101242","pmid":"https://pubmed.ncbi.nlm.nih.gov/38868170","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11167691"},"language":"en","primary_location":{"id":"doi:10.1016/j.crmeth.2025.101242","doi":"https://doi.org/10.1016/j.crmeth.2025.101242","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.crmeth.2025.101242","pdf_url":null,"source":{"id":"https://openalex.org/S4210214705","display_name":"Cell Reports Methods","issn_l":"2667-2375","issn":["2667-2375"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports Methods","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.crmeth.2025.101242","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048377134","display_name":"Gautam S. Sabnis","orcid":"https://orcid.org/0000-0002-9985-7463","observed_orcids":["https://orcid.org/0000-0002-9985-7463"]},"institutions":[{"id":"https://openalex.org/I4210115256","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gautam S. Sabnis","raw_affiliation_strings":["The Jackson Laboratory, Bar Harbor, ME 04609, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Jackson Laboratory, Bar Harbor, ME 04609, USA","institution_ids":["https://openalex.org/I4210115256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010535372","display_name":"Leinani E. Hession","orcid":"https://orcid.org/0000-0002-2257-801X","observed_orcids":["https://orcid.org/0000-0002-2257-801X"]},"institutions":[{"id":"https://openalex.org/I4210115256","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leinani Hession","raw_affiliation_strings":["The Jackson Laboratory, Bar Harbor, ME 04609, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Jackson Laboratory, Bar Harbor, ME 04609, USA","institution_ids":["https://openalex.org/I4210115256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033950605","display_name":"J. Matthew Mahoney","orcid":"https://orcid.org/0000-0003-1425-5939","observed_orcids":["https://orcid.org/0000-0003-1425-5939"]},"institutions":[{"id":"https://openalex.org/I4210115256","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Matthew Mahoney","raw_affiliation_strings":["The Jackson Laboratory, Bar Harbor, ME 04609, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Jackson Laboratory, Bar Harbor, ME 04609, USA","institution_ids":["https://openalex.org/I4210115256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038146363","display_name":"Arie Sitthichai Mobley","orcid":"https://orcid.org/0000-0002-0417-9082","observed_orcids":["https://orcid.org/0000-0002-0417-9082"]},"institutions":[{"id":"https://openalex.org/I4210115256","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arie Mobley","raw_affiliation_strings":["The Jackson Laboratory, Bar Harbor, ME 04609, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Jackson Laboratory, Bar Harbor, ME 04609, USA","institution_ids":["https://openalex.org/I4210115256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102679974","display_name":"Marina dos Santos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115256","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marina Santos","raw_affiliation_strings":["The Jackson Laboratory, Bar Harbor, ME 04609, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Jackson Laboratory, Bar Harbor, ME 04609, USA","institution_ids":["https://openalex.org/I4210115256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066356266","display_name":"Brian Q. Geuther","orcid":"https://orcid.org/0000-0002-7822-486X","observed_orcids":["https://orcid.org/0000-0002-7822-486X"]},"institutions":[{"id":"https://openalex.org/I4210115256","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian Geuther","raw_affiliation_strings":["The Jackson Laboratory, Bar Harbor, ME 04609, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Jackson Laboratory, Bar Harbor, ME 04609, USA","institution_ids":["https://openalex.org/I4210115256"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100357359","display_name":"Vivek Kumar","orcid":"https://orcid.org/0000-0001-6643-7465","observed_orcids":["https://orcid.org/0000-0001-6643-7465"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I4210115256","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256"]},{"id":"https://openalex.org/I7947594","display_name":"University of Maine","ror":"https://ror.org/01adr0w49","country_code":"US","type":"education","lineage":["https://openalex.org/I2802397601","https://openalex.org/I7947594"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Vivek Kumar","raw_affiliation_strings":["The Jackson Laboratory, Bar Harbor, ME 04609, USA; School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME 04469, USA. Electronic address: vivek.kumar@jax.org"],"raw_orcid":"https://orcid.org/0000-0001-6643-7465","affiliations":[{"raw_affiliation_string":"The Jackson Laboratory, Bar Harbor, ME 04609, USA; School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME 04469, USA. Electronic address: vivek.kumar@jax.org","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I4210115256","https://openalex.org/I7947594"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100357359"],"corresponding_institution_ids":["https://openalex.org/I121934306","https://openalex.org/I4210115256","https://openalex.org/I7947594"],"apc_list":{"value":4824,"currency":"USD","value_usd":4824},"apc_paid":{"value":4824,"currency":"USD","value_usd":4824},"fwci":7.124,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.97939102,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"5","issue":"12","first_page":"101242","last_page":"101242"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.014800000004470348,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10812","display_name":"Human Pose and Action Recognition","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/seizure-detection","display_name":"seizure detection","score":0.9520000219345093},{"id":"https://openalex.org/keywords/pentylenetetrazole-induced-seizures","display_name":"pentylenetetrazole-induced seizures","score":0.8700000047683716},{"id":"https://openalex.org/keywords/mouse-model-of-epilepsy","display_name":"mouse model of epilepsy","score":0.5830000042915344},{"id":"https://openalex.org/keywords/racine-scale","display_name":"Racine scale","score":0.8659999966621399}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7210000157356262},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.6607000231742859},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5390999913215637},{"id":"https://openalex.org/C17755696","wikidata":"https://www.wikidata.org/wiki/Q16564780","display_name":"Ictal","level":3,"score":0.5320000052452087},{"id":"https://openalex.org/C2779334592","wikidata":"https://www.wikidata.org/wiki/Q6279182","display_name":"Epileptic seizure","level":3,"score":0.44190001487731934},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4032999873161316},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.3693000078201294},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.3659999966621399},{"id":"https://openalex.org/C2776058522","wikidata":"https://www.wikidata.org/wiki/Q2364768","display_name":"Visual field","level":2,"score":0.3617999851703644},{"id":"https://openalex.org/C136389625","wikidata":"https://www.wikidata.org/wiki/Q334384","display_name":"Supervised learning","level":3,"score":0.3564999997615814},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.3422999978065491},{"id":"https://openalex.org/C28490314","wikidata":"https://www.wikidata.org/wiki/Q189436","display_name":"Speech recognition","level":1,"score":0.31040000915527344},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.30390000343322754},{"id":"https://openalex.org/C168820333","wikidata":"https://www.wikidata.org/wiki/Q448889","display_name":"Visual inspection","level":2,"score":0.2727000117301941},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.26809999346733093},{"id":"https://openalex.org/C9652623","wikidata":"https://www.wikidata.org/wiki/Q190109","display_name":"Field (mathematics)","level":2,"score":0.26759999990463257},{"id":"https://openalex.org/C178253425","wikidata":"https://www.wikidata.org/wiki/Q162668","display_name":"Visual perception","level":3,"score":0.2603999972343445},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.2554999887943268},{"id":"https://openalex.org/C111151474","wikidata":"https://www.wikidata.org/wiki/Q1653368","display_name":"iCub","level":4,"score":0.2549999952316284},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.25450000166893005},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.25029999017715454}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1016/j.crmeth.2025.101242","doi":"https://doi.org/10.1016/j.crmeth.2025.101242","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.crmeth.2025.101242","pdf_url":null,"source":{"id":"https://openalex.org/S4210214705","display_name":"Cell Reports Methods","issn_l":"2667-2375","issn":["2667-2375"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports Methods","raw_type":"journal-article"},{"id":"doi:10.1101/2024.05.29.596520","doi":"https://doi.org/10.1101/2024.05.29.596520","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2024.05.29.596520","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:europepmc.org:11667135","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12859513","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:38868170","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38868170","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"bioRxiv : the preprint server for biology","raw_type":"Journal Article"},{"id":"pmid:41308647","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41308647","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell reports methods","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12859513","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12859513/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Rep Methods","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:11167691","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11167691","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11167691/pdf/nihpp-2024.05.29.596520v1.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.crmeth.2025.101242","doi":"https://doi.org/10.1016/j.crmeth.2025.101242","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.crmeth.2025.101242","pdf_url":null,"source":{"id":"https://openalex.org/S4210214705","display_name":"Cell Reports Methods","issn_l":"2667-2375","issn":["2667-2375"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports Methods","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4912625681","display_name":"Machine learning based frailty index for the genetically diverse mice","funder_award_id":"R61AG078530","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G5151917128","display_name":null,"funder_award_id":"DA051235","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G5320618627","display_name":null,"funder_award_id":"AG078530","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6149589070","display_name":null,"funder_award_id":"DA048634","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G7522693891","display_name":"Application of Machine Vision to Determine the Influence of Sleep States and Social Interactions on Vulnerability to Drug Addiction","funder_award_id":"R21DA048634","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G9000889385","display_name":"Establishment and Characterization of Novel Mutant Mouse Models for the Addiction Research Community","funder_award_id":"U01DA051235","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G9000896028","display_name":"Machine learning based frailty index for the genetically diverse mice","funder_award_id":"R33AG078530","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320308826","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4416701713.pdf","grobid_xml":"https://content.openalex.org/works/W4416701713.grobid-xml"},"referenced_works_count":74,"referenced_works":["https://openalex.org/W220395373","https://openalex.org/W1749057191","https://openalex.org/W1922096799","https://openalex.org/W1966728711","https://openalex.org/W1971950880","https://openalex.org/W1977591411","https://openalex.org/W1992356332","https://openalex.org/W2017500569","https://openalex.org/W2033988285","https://openalex.org/W2034920727","https://openalex.org/W2041557338","https://openalex.org/W2048306317","https://openalex.org/W2053154970","https://openalex.org/W2056787619","https://openalex.org/W2083974405","https://openalex.org/W2085860474","https://openalex.org/W2086841066","https://openalex.org/W2103946141","https://openalex.org/W2114512542","https://openalex.org/W2122825543","https://openalex.org/W2135046866","https://openalex.org/W2140794498","https://openalex.org/W2154723612","https://openalex.org/W2219858099","https://openalex.org/W2397008233","https://openalex.org/W2587877487","https://openalex.org/W2669857762","https://openalex.org/W2787894218","https://openalex.org/W2793070938","https://openalex.org/W2894383222","https://openalex.org/W2898611747","https://openalex.org/W2940794125","https://openalex.org/W2952213141","https://openalex.org/W2952992838","https://openalex.org/W2960399794","https://openalex.org/W2990943996","https://openalex.org/W2991391187","https://openalex.org/W3001888977","https://openalex.org/W3007271284","https://openalex.org/W3013377162","https://openalex.org/W3014641072","https://openalex.org/W3019362658","https://openalex.org/W3022577698","https://openalex.org/W3081414515","https://openalex.org/W3087722312","https://openalex.org/W3098086214","https://openalex.org/W3098415558","https://openalex.org/W3119267769","https://openalex.org/W3133716463","https://openalex.org/W3137049560","https://openalex.org/W3151062433","https://openalex.org/W3197246522","https://openalex.org/W3197672892","https://openalex.org/W3210419626","https://openalex.org/W4206326164","https://openalex.org/W4206651841","https://openalex.org/W4206951326","https://openalex.org/W4211147755","https://openalex.org/W4212840236","https://openalex.org/W4220731372","https://openalex.org/W4292065802","https://openalex.org/W4307776247","https://openalex.org/W4309191770","https://openalex.org/W4309473115","https://openalex.org/W4311673829","https://openalex.org/W4313283149","https://openalex.org/W4321782624","https://openalex.org/W4362523794","https://openalex.org/W4386332807","https://openalex.org/W4388847722","https://openalex.org/W4390415053","https://openalex.org/W4392385217","https://openalex.org/W4393110839","https://openalex.org/W4400580347"],"related_works":["https://openalex.org/W7222936449","https://openalex.org/W7221764055","https://openalex.org/W4388169044","https://openalex.org/W4408101927","https://openalex.org/W4407862037","https://openalex.org/W3043597093","https://openalex.org/W4223971303","https://openalex.org/W4386945013","https://openalex.org/W4414161938","https://openalex.org/W4392861152"],"abstract_inverted_index":{"Seizures":[0],"are":[1,27,78],"caused":[2],"by":[3],"abnormally":[4],"synchronous":[5],"brain":[6],"activity":[7],"that":[8,77,144],"can":[9,150],"result":[10],"in":[11,13,40,48,54,107,160],"changes":[12],"muscle":[14],"tone,":[15],"such":[16,43,180],"as":[17,44,130,132,181],"twitching,":[18],"stiffness,":[19],"limpness,":[20],"or":[21],"rhythmic":[22],"jerking.":[23],"These":[24,168],"behavioral":[25,52],"manifestations":[26],"clear":[28],"on":[29],"visual":[30,60],"inspection":[31,61],"and":[32,65,68,147,173,183],"the":[33,45,103,141],"most":[34],"widely":[35],"used":[36,84],"seizure":[37,56,95,105,124,134,145,175],"scoring":[38,176],"systems":[39],"preclinical":[41],"models,":[42],"Racine":[46],"scale":[47],"rodents,":[49],"use":[50],"these":[51,118],"patterns":[53],"semiquantitative":[55],"intensity":[57,125,135,149],"scores.":[58,136],"However,":[59],"is":[62,70],"time-consuming,":[63],"low-throughput,":[64],"partially":[66],"subjective,":[67],"there":[69],"a":[71,127,161],"need":[72],"for":[73,126,140,177],"rigorously":[74,152],"quantitative":[75],"approaches":[76,88],"scalable.":[79],"In":[80],"this":[81],"study,":[82],"we":[83,109],"supervised":[85,166],"machine":[86],"learning":[87],"to":[89,93,113,120],"develop":[90],"automated":[91],"classifiers":[92,112],"predict":[94,114,121],"severity":[96],"directly":[97,154],"from":[98,155],"noninvasive":[99],"video":[100,157],"data.":[101],"Using":[102],"PTZ-induced":[104],"model":[106],"mice,":[108],"trained":[110],"video-only":[111],"ictal":[115],"events,":[116],"combined":[117],"events":[119,146],"an":[122],"univariate":[123],"recording":[128],"session,":[129],"well":[131],"time-varying":[133],"Our":[137],"results":[138,169],"show,":[139],"first":[142],"time,":[143],"overall":[148],"be":[151],"quantified":[153],"overhead":[156],"of":[158],"mice":[159],"standard":[162],"open":[163],"field":[164],"using":[165],"approaches.":[167],"enable":[170],"high-throughput,":[171],"noninvasive,":[172],"standardized":[174],"downstream":[178],"applications":[179],"neurogenetics":[182],"therapeutic":[184],"discovery.":[185]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-11-27T00:00:00"}