{"id":"https://openalex.org/W4416699465","doi":"https://doi.org/10.1016/j.chest.2025.07.541","title":"A DOUBLE-EDGED PILL: ASPIRIN-INDUCED KOUNIS SYNDROME","display_name":"A DOUBLE-EDGED PILL: ASPIRIN-INDUCED KOUNIS SYNDROME","publication_year":2025,"publication_date":"2025-10-01","ids":{"openalex":"https://openalex.org/W4416699465","doi":"https://doi.org/10.1016/j.chest.2025.07.541"},"language":"en","primary_location":{"id":"doi:10.1016/j.chest.2025.07.541","doi":"https://doi.org/10.1016/j.chest.2025.07.541","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.chest.2025.07.541","pdf_url":null,"source":{"id":"https://openalex.org/S76900504","display_name":"CHEST Journal","issn_l":"0012-3692","issn":["0012-3692","1931-3543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"CHEST","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051967201","display_name":"Ricardo J. Estrada-Mendiz\u00e1bal","orcid":"https://orcid.org/0000-0001-8593-4504","observed_orcids":["https://orcid.org/0000-0001-8593-4504"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"RICARDO J ESTRADA-MENDIZABAL","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"SAIYARA SHEIKH","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"SAIYARA SHEIKH","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"JUAN F. RODRIGUEZ","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JUAN F. RODRIGUEZ","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026673213","display_name":"Sergio E. Chiarella","orcid":"https://orcid.org/0000-0002-0445-4929","observed_orcids":["https://orcid.org/0000-0002-0445-4929"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"SERGIO CHIARELLA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5045897876","display_name":"Alexei Gonzalez\u2010Estrada","orcid":"https://orcid.org/0000-0002-5754-6130","observed_orcids":["https://orcid.org/0000-0002-5754-6130"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"ALEXEI GONZALEZ-ESTRADA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4160,"currency":"USD","value_usd":4160},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.31776969,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"168","issue":"4","first_page":"A922","last_page":"A923"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.3043999969959259,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.3043999969959259,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.11580000072717667,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11917","display_name":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","score":0.10660000145435333,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kounis-syndrome","display_name":"Kounis syndrome","score":0.8820000290870667},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.9879999756813049},{"id":"https://openalex.org/keywords/drug-induced-asthma","display_name":"drug-induced asthma","score":0.5099999904632568},{"id":"https://openalex.org/keywords/adverse-drug-reactions","display_name":"adverse drug reactions","score":0.3009999990463257}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5006999969482422},{"id":"https://openalex.org/C2781372229","wikidata":"https://www.wikidata.org/wiki/Q6434647","display_name":"Kounis syndrome","level":4,"score":0.26759999990463257},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17489999532699585},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.17180000245571136},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.16850000619888306},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.1679999977350235},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.16599999368190765},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.16509999334812164},{"id":"https://openalex.org/C90673727","wikidata":"https://www.wikidata.org/wiki/Q901718","display_name":"Product (mathematics)","level":2,"score":0.15600000321865082},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.15309999883174896}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.chest.2025.07.541","doi":"https://doi.org/10.1016/j.chest.2025.07.541","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.chest.2025.07.541","pdf_url":null,"source":{"id":"https://openalex.org/S76900504","display_name":"CHEST Journal","issn_l":"0012-3692","issn":["0012-3692","1931-3543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"CHEST","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2130525296","https://openalex.org/W2047166562","https://openalex.org/W2888875677","https://openalex.org/W7100319885","https://openalex.org/W2464694672","https://openalex.org/W2168436288","https://openalex.org/W2327759554","https://openalex.org/W4389728732","https://openalex.org/W1998947124","https://openalex.org/W1980698590"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2025-11-27T00:00:00"}