{"id":"https://openalex.org/W4416634182","doi":"https://doi.org/10.1183/13993003.congress-2025.oa6462","title":"Multi-domain cognitive function in COPD and matched controls: Baseline data from the COPD-HIIT randomised controlled trial","display_name":"Multi-domain cognitive function in COPD and matched controls: Baseline data from the COPD-HIIT randomised controlled trial","publication_year":2025,"publication_date":"2025-09-27","ids":{"openalex":"https://openalex.org/W4416634182","doi":"https://doi.org/10.1183/13993003.congress-2025.oa6462"},"language":"en","primary_location":{"id":"doi:10.1183/13993003.congress-2025.oa6462","doi":"https://doi.org/10.1183/13993003.congress-2025.oa6462","is_oa":false,"landing_page_url":"https://doi.org/10.1183/13993003.congress-2025.oa6462","pdf_url":null,"source":{"id":"https://openalex.org/S4210207896","display_name":"European Respiratory Journal","issn_l":"0903-1936","issn":["0903-1936","1399-3003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317833","host_organization_name":"European Respiratory Society","host_organization_lineage":["https://openalex.org/P4310317833"],"host_organization_lineage_names":["European Respiratory Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiotherapists","raw_type":"proceedings-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000699796","display_name":"Johan Jakobsson","orcid":"https://orcid.org/0000-0002-9816-194X","observed_orcids":["https://orcid.org/0000-0002-9816-194X"]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Johan Jakobsson","raw_affiliation_strings":["1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037949431","display_name":"Dries Cops","orcid":"https://orcid.org/0000-0002-0044-0677","observed_orcids":["https://orcid.org/0000-0002-0044-0677"]},"institutions":[{"id":"https://openalex.org/I878454856","display_name":"Hasselt University","ror":"https://ror.org/04nbhqj75","country_code":"BE","type":"education","lineage":["https://openalex.org/I878454856"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Dries Cops","raw_affiliation_strings":["2REVAL \u2013 Rehabilitation Research Center, BIOMED \u2013 Biomedical Research Institute, Hasselt, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2REVAL \u2013 Rehabilitation Research Center, BIOMED \u2013 Biomedical Research Institute, Hasselt, Belgium","institution_ids":["https://openalex.org/I878454856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060625922","display_name":"Jonas Westman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jonas Westman","raw_affiliation_strings":["1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120613163","display_name":"Evelina Sund","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Evelina Sund","raw_affiliation_strings":["1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085087940","display_name":"Mattias Hedlund","orcid":"https://orcid.org/0000-0002-3844-9247","observed_orcids":["https://orcid.org/0000-0002-3844-9247"]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Mattias Hedlund","raw_affiliation_strings":["1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015443776","display_name":"Thomas Sandstr\u00f6m","orcid":"https://orcid.org/0000-0002-0174-0882","observed_orcids":["https://orcid.org/0000-0002-0174-0882"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas Sandstr\u00f6m","raw_affiliation_strings":["3Department of Public Health and Clinical Medicine, Ume\u00e5, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Department of Public Health and Clinical Medicine, Ume\u00e5, Sweden","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004694001","display_name":"David Ruttens","orcid":"https://orcid.org/0009-0008-4462-1622","observed_orcids":["https://orcid.org/0009-0008-4462-1622","https://orcid.org/0000-0002-7284-6393"]},"institutions":[{"id":"https://openalex.org/I4210148648","display_name":"Ziekenhuis Oost-Limburg","ror":"https://ror.org/04fg7az81","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210148648"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"David Ruttens","raw_affiliation_strings":["4Department of Respiratory Diseases, Ziekenhuis Oost-Limburg, Genk, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Department of Respiratory Diseases, Ziekenhuis Oost-Limburg, Genk, Belgium","institution_ids":["https://openalex.org/I4210148648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072435600","display_name":"Marc Daenen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148648","display_name":"Ziekenhuis Oost-Limburg","ror":"https://ror.org/04fg7az81","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210148648"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Marc Daenen","raw_affiliation_strings":["4Department of Respiratory Diseases, Ziekenhuis Oost-Limburg, Genk, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Department of Respiratory Diseases, Ziekenhuis Oost-Limburg, Genk, Belgium","institution_ids":["https://openalex.org/I4210148648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079696781","display_name":"Jana De Brandt","orcid":"https://orcid.org/0000-0003-3463-1911","observed_orcids":["https://orcid.org/0000-0003-3463-1911"]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jana De Brandt","raw_affiliation_strings":["1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070330332","display_name":"Chris Burtin","orcid":"https://orcid.org/0000-0002-1342-8554","observed_orcids":["https://orcid.org/0000-0002-1342-8554"]},"institutions":[{"id":"https://openalex.org/I878454856","display_name":"Hasselt University","ror":"https://ror.org/04nbhqj75","country_code":"BE","type":"education","lineage":["https://openalex.org/I878454856"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Chris Burtin","raw_affiliation_strings":["2REVAL \u2013 Rehabilitation Research Center, BIOMED \u2013 Biomedical Research Institute, Hasselt, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2REVAL \u2013 Rehabilitation Research Center, BIOMED \u2013 Biomedical Research Institute, Hasselt, Belgium","institution_ids":["https://openalex.org/I878454856"]}]},{"author_position":"last","author":{"id":null,"display_name":"Andr\u00e9 Nyberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Andr\u00e9 Nyberg","raw_affiliation_strings":["1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5, Sweden","institution_ids":["https://openalex.org/I90267481"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"OA6462","last_page":"OA6462"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11368","display_name":"Long-Term Effects of COVID-19","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.7960000038146973},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.9950000047683716},{"id":"https://openalex.org/keywords/exercise-capacity","display_name":"exercise capacity","score":0.7749999761581421},{"id":"https://openalex.org/keywords/anaerobic-capacity","display_name":"anaerobic capacity","score":0.8420000076293945},{"id":"https://openalex.org/keywords/systemic-inflammation","display_name":"systemic inflammation","score":0.8809999823570251},{"id":"https://openalex.org/keywords/fibrinogen","display_name":"fibrinogen","score":0.9959999918937683},{"id":"https://openalex.org/keywords/peak-oxygen-uptake","display_name":"peak oxygen uptake","score":0.5149999856948853},{"id":"https://openalex.org/keywords/trail-making-test","display_name":"Trail Making Test","score":0.6179999709129333},{"id":"https://openalex.org/keywords/visuospatial-processing","display_name":"visuospatial processing","score":0.6169999837875366},{"id":"https://openalex.org/keywords/memory","display_name":"memory","score":0.6959999799728394},{"id":"https://openalex.org/keywords/high-intensity-interval-training","display_name":"high-intensity interval training","score":0.8299999833106995}],"concepts":[{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.760699987411499},{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.6735000014305115},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6484000086784363},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.6477000117301941},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5367000102996826},{"id":"https://openalex.org/C2776252253","wikidata":"https://www.wikidata.org/wiki/Q7663815","display_name":"Systemic inflammation","level":3,"score":0.44769999384880066},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.4336000084877014},{"id":"https://openalex.org/C103038586","wikidata":"https://www.wikidata.org/wiki/Q1152037","display_name":"Aerobic exercise","level":2,"score":0.4293999969959259},{"id":"https://openalex.org/C185711340","wikidata":"https://www.wikidata.org/wiki/Q5347381","display_name":"Effects of sleep deprivation on cognitive performance","level":3,"score":0.4090999960899353},{"id":"https://openalex.org/C181588539","wikidata":"https://www.wikidata.org/wiki/Q219067","display_name":"Physical exercise","level":2,"score":0.3806000053882599},{"id":"https://openalex.org/C5140985","wikidata":"https://www.wikidata.org/wiki/Q483866","display_name":"Anaerobic exercise","level":2,"score":0.37940001487731934},{"id":"https://openalex.org/C3018587741","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung function","level":3,"score":0.37529999017715454},{"id":"https://openalex.org/C171687745","wikidata":"https://www.wikidata.org/wiki/Q309252","display_name":"Physical fitness","level":2,"score":0.2937999963760376},{"id":"https://openalex.org/C134290984","wikidata":"https://www.wikidata.org/wiki/Q5141241","display_name":"Cognitive skill","level":3,"score":0.29109999537467957},{"id":"https://openalex.org/C75603125","wikidata":"https://www.wikidata.org/wiki/Q1877462","display_name":"Pulmonary function testing","level":2,"score":0.2883000075817108},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28200000524520874},{"id":"https://openalex.org/C117437137","wikidata":"https://www.wikidata.org/wiki/Q5038720","display_name":"Cardiorespiratory fitness","level":2,"score":0.2791000008583069},{"id":"https://openalex.org/C6057870","wikidata":"https://www.wikidata.org/wiki/Q5141248","display_name":"Cognitive test","level":3,"score":0.27549999952316284},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.27549999952316284},{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.2685999870300293},{"id":"https://openalex.org/C151243789","wikidata":"https://www.wikidata.org/wiki/Q17148646","display_name":"Multiple baseline design","level":3,"score":0.2678999900817871},{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.260699987411499}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1183/13993003.congress-2025.oa6462","doi":"https://doi.org/10.1183/13993003.congress-2025.oa6462","is_oa":false,"landing_page_url":"https://doi.org/10.1183/13993003.congress-2025.oa6462","pdf_url":null,"source":{"id":"https://openalex.org/S4210207896","display_name":"European Respiratory Journal","issn_l":"0903-1936","issn":["0903-1936","1399-3003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317833","host_organization_name":"European Respiratory Society","host_organization_lineage":["https://openalex.org/P4310317833"],"host_organization_lineage_names":["European Respiratory Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiotherapists","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2775842516","https://openalex.org/W2222437037","https://openalex.org/W1964618575","https://openalex.org/W4391957848","https://openalex.org/W4301378423","https://openalex.org/W4312330352","https://openalex.org/W2619146610","https://openalex.org/W2093630090","https://openalex.org/W2990046396","https://openalex.org/W4312651613"],"abstract_inverted_index":{"Background":[0],"Cognitive":[1,154,172],"impairment":[2,155],"is":[3,14],"increasingly":[4],"recognized":[5],"as":[6],"an":[7],"extrapulmonary":[8],"manifestation":[9],"of":[10,74],"COPD,":[11,109,161],"yet":[12],"little":[13],"known":[15],"across":[16,100,157],"cognitive":[17,33,58,98],"domains":[18,102,159],"and":[19,24,29,37,40,47,53,69,80,89,128,146,169,183],"associations":[20,49],"with":[21,50,67,113,143,165,186],"exercise":[22,51,75,181],"capacities":[23],"inflammation":[25,90,188],"remain":[26],"underexplored.":[27],"Aims":[28],"objectives:":[30],"To":[31],"compare":[32],"function":[34,59,99],"in":[35,64,160,163,189],"COPD":[36,68,94],"age-,":[38],"sex-":[39],"physical":[41],"activity":[42],"matched":[43,71],"healthy":[44],"controls":[45],"(HCs)":[46],"examine":[48],"performance":[52,76,148],"systemic":[54,187],"inflammation.":[55],"Methods:":[56],"Multi-domain":[57],"was":[60],"assessed":[61],"at":[62],"baseline":[63],"44":[65],"individuals":[66],"39":[70],"HCs.":[72],"Correlations":[73],"including":[77],"CPET":[78,134],"Wpeak":[79,111,135],"anaerobic":[81],"capacity":[82,182],"(Borg":[83],"cycle":[84],"strength":[85],"test":[86],"[BCST":[87],"Wpeak])":[88],"were":[91,174,184],"analysed.":[92],"Results:":[93],"participants":[95],"exhibited":[96],"lower":[97],"most":[101],"compared":[103],"to":[104,176],"HCs":[105],"(Table":[106],"1).":[107],"In":[108],"BCST":[110],"correlated":[112,142],"trail":[114],"making":[115],"tests":[116],"([TMT]":[117],"TMT-A:":[118],"r=-.43;":[119],"TMT-B:":[120],"r=-.32;":[121],"p<0.05))":[122],"visual":[123],"processing":[124],"(VP1:":[125],"r=.43;":[126],"p<0.05)":[127],"memory":[129],"(PAL:":[130],"r=.35;":[131],"p<0.05),":[132],"while":[133],"showed":[136],"no":[137],"associations.":[138],"Higher":[139],"fibrinogen":[140],"levels":[141],"poorer":[144],"TMT-B":[145],"PAL1":[147],"(r=.38":[149],"&":[150],"r=-.40;":[151],"p<0.05).":[152],"Conclusion:":[153],"spans":[156],"multiple":[158],"even":[162],"those":[164],"relatively":[166],"preserved":[167],"fitness":[168],"lung":[170],"function.":[171],"deficits":[173],"associated":[175,185],"anaerobic,":[177],"but":[178,191],"not":[179,192],"aerobic":[180],"some,":[190],"all":[193],"domains.":[194],"erj;66/suppl_69/OA6462/F1":[195],"F1":[196,197]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-11-25T00:00:00"}