{"id":"https://openalex.org/W4416631940","doi":"https://doi.org/10.5256/f1000research.147199.r176727","title":"Peer Review Report For: Effect of proprioceptive neuromuscular facilitation technique and TENS on improving lower limb sensorimotor function, balance and quality of life in chemotherapy induced peripheral neuropathy in gynecological cancer: A randomized controlled trial protocol [version 1; peer review: 1 approved]","display_name":"Peer Review Report For: Effect of proprioceptive neuromuscular facilitation technique and TENS on improving lower limb sensorimotor function, balance and quality of life in chemotherapy induced peripheral neuropathy in gynecological cancer: A randomized controlled trial protocol [version 1; peer review: 1 approved]","publication_year":2023,"publication_date":"2023-08-16","ids":{"openalex":"https://openalex.org/W4416631940","doi":"https://doi.org/10.5256/f1000research.147199.r176727"},"language":"en","primary_location":{"id":"doi:10.5256/f1000research.147199.r176727","doi":"https://doi.org/10.5256/f1000research.147199.r176727","is_oa":true,"landing_page_url":"https://doi.org/10.5256/f1000research.147199.r176727","pdf_url":"https://f1000research.com/articles/12-527/pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nitte (deemed to be) University","raw_type":"peer-review"},"volume":null,"type":"peer-review","indexed_in":["crossref","datacite"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://f1000research.com/articles/12-527/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005992940","display_name":"Nikita H Seth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130476","display_name":"Datta Meghe Institute of Higher Education and Research","ror":"https://ror.org/02w7k5y22","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210130476"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Nikita H. Seth","raw_affiliation_strings":["Neuro Physiotherapy, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuro Physiotherapy, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001","institution_ids":["https://openalex.org/I4210130476"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108317004","display_name":"Moh\u2019d Irshad Quershi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130476","display_name":"Datta Meghe Institute of Higher Education and Research","ror":"https://ror.org/02w7k5y22","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210130476"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Irshad Quershi","raw_affiliation_strings":["Neuro Physiotherapy, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuro Physiotherapy, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001","institution_ids":["https://openalex.org/I4210130476"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5005992940"],"corresponding_institution_ids":["https://openalex.org/I4210130476"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11752","display_name":"Cancer Treatment and Pharmacology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11752","display_name":"Cancer Treatment and Pharmacology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12937","display_name":"Chemotherapy-related skin toxicity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemotherapy-induced-peripheral-neuropathy","display_name":"chemotherapy-induced peripheral neuropathy","score":0.8410000205039978},{"id":"https://openalex.org/keywords/gynecologic-cancer","display_name":"gynecologic cancer","score":0.8709999918937683},{"id":"https://openalex.org/keywords/proprioceptive-neuromuscular-facilitation","display_name":"proprioceptive neuromuscular facilitation","score":0.9959999918937683},{"id":"https://openalex.org/keywords/transcutaneous-electrical-nerve-stimulation","display_name":"transcutaneous electrical nerve stimulation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/closed-kinetic-chain-exercises","display_name":"closed kinetic chain exercises","score":0.9380000233650208},{"id":"https://openalex.org/keywords/balance","display_name":"balance","score":0.984000027179718},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.9959999918937683},{"id":"https://openalex.org/keywords/physiotherapy-intervention","display_name":"physiotherapy intervention","score":0.7379999756813049}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8339999914169312},{"id":"https://openalex.org/C171790689","wikidata":"https://www.wikidata.org/wiki/Q1129066","display_name":"Proprioception","level":2,"score":0.758899986743927},{"id":"https://openalex.org/C168031717","wikidata":"https://www.wikidata.org/wiki/Q1530280","display_name":"Balance (ability)","level":2,"score":0.7239000201225281},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.6812000274658203},{"id":"https://openalex.org/C1337776","wikidata":"https://www.wikidata.org/wiki/Q1941955","display_name":"Facilitation","level":2,"score":0.6340000033378601},{"id":"https://openalex.org/C2779289229","wikidata":"https://www.wikidata.org/wiki/Q17153857","display_name":"Chemotherapy-induced peripheral neuropathy","level":4,"score":0.593500018119812},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5892000198364258},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.5648999810218811},{"id":"https://openalex.org/C2989316616","wikidata":"https://www.wikidata.org/wiki/Q6027402","display_name":"Lower limb","level":2,"score":0.548799991607666},{"id":"https://openalex.org/C2779901536","wikidata":"https://www.wikidata.org/wiki/Q945238","display_name":"Peripheral neuropathy","level":3,"score":0.5270000100135803},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.5188999772071838},{"id":"https://openalex.org/C46762472","wikidata":"https://www.wikidata.org/wiki/Q178648","display_name":"Peripheral","level":2,"score":0.4733999967575073},{"id":"https://openalex.org/C130093455","wikidata":"https://www.wikidata.org/wiki/Q173253","display_name":"Sensation","level":2,"score":0.35120001435279846},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.31439998745918274},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.27709999680519104},{"id":"https://openalex.org/C2777515770","wikidata":"https://www.wikidata.org/wiki/Q507369","display_name":"Electromyography","level":2,"score":0.272599995136261},{"id":"https://openalex.org/C3020056645","wikidata":"https://www.wikidata.org/wiki/Q1327643","display_name":"Electric stimulation","level":3,"score":0.26269999146461487},{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.2531000077724457}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.5256/f1000research.147199.r176727","doi":"https://doi.org/10.5256/f1000research.147199.r176727","is_oa":true,"landing_page_url":"https://doi.org/10.5256/f1000research.147199.r176727","pdf_url":"https://f1000research.com/articles/12-527/pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nitte (deemed to be) University","raw_type":"peer-review"},{"id":"doi:10.5256/f1000research.147199.r176727","doi":"https://doi.org/10.5256/f1000research.147199.r176727","is_oa":true,"landing_page_url":"https://doi.org/10.5256/f1000research.147199.r176727","pdf_url":null,"source":{"id":"https://openalex.org/S7407050752","display_name":"Faculty of 1000 Research Ltd","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.5256/f1000research.147199.r176727","doi":"https://doi.org/10.5256/f1000research.147199.r176727","is_oa":true,"landing_page_url":"https://doi.org/10.5256/f1000research.147199.r176727","pdf_url":"https://f1000research.com/articles/12-527/pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nitte (deemed to be) University","raw_type":"peer-review"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4416631940.pdf","grobid_xml":"https://content.openalex.org/works/W4416631940.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Gynecological":[0,178],"cancers":[1,6],"are":[2,18,79,85],"the":[3,53,101,111,131,140,152,204,215,225,260,287],"most":[4],"prevalent":[5],"in":[7,56,100,114,177,180,203,230,275,285],"women,":[8],"making":[9],"it":[10,97,120,282],"a":[11,57,118,146,231],"significant":[12],"public":[13],"health":[14],"concern.":[15],"Chemotherapy":[16],"drugs":[17,45],"an":[19],"extremely":[20],"effective":[21],"approach":[22],"for":[23,220,256],"reducing":[24,286],"cancer":[25,41,115],"progression":[26],"since":[27],"they":[28],"have":[29],"various":[30],"targets":[31],"and":[32,50,77,166,213,249],"mechanism":[33],"of":[34,52,59,81,105,154,198,247,254,262,277,289,291],"action":[35],"focused":[36],"at":[37],"killing":[38],"quickly":[39],"multiplying":[40],"cells.":[42],"Unfortunately,":[43],"these":[44],"also":[46],"affect":[47],"normal":[48],"cells":[49],"structures":[51],"body,":[54],"resulting":[55],"variety":[58],"deleterious":[60],"effects.":[61],"Most":[62],"common":[63],"among":[64],"them":[65],"is":[66,121],"chemotherapy":[67,95,106,292],"induced":[68],"peripheral":[69],"neuropathy":[70],"(CIPN).":[71],"Taxanes,":[72],"platinum":[73],"medicines,":[74],"vinca":[75],"alkaloids":[76],"thalidomide":[78],"examples":[80],"popular":[82],"pharmaceuticals":[83],"that":[84,123,134],"prone":[86],"to":[87,128,150,223,266,295],"cause":[88],"CIPN.":[89,278],"When":[90],"CIPN":[91,176],"develops":[92],"during":[93],"active":[94],"phase,":[96],"may":[98,109],"result":[99],"discontinuation":[102,290],"or":[103],"reduction":[104],"dose,":[107],"which":[108,148],"render":[110],"dosage":[112],"ineffective":[113],"management.":[116],"As":[117],"result,":[119],"essential":[122],"physiotherapists":[124],"investigate":[125],"novel":[126],"approaches":[127],"successfully":[129],"manage":[130],"side":[132],"effects":[133],"survivors":[135],"must":[136],"deal":[137],"with.":[138],"Here\u2019s":[139],"idea":[141],"we":[142],"suggest":[143],"by":[144],"conducting":[145],"study":[147,205,264],"aim":[149],"assess":[151],"effectiveness":[153],"Proprioceptive":[155],"Neuromuscular":[156],"Facilitation":[157],"Technique":[158],"(PNF)":[159],"with":[160,171,175,227,233,280],"Transcutaneous":[161],"Electrical":[162],"Nerve":[163],"Stimulation":[164],"(TENS)":[165],"closed":[167],"kinetic":[168],"chain":[169],"exercises":[170],"TENS":[172],"on":[173,189],"subjects":[174],"Cancer":[179],"two":[181,210],"arm":[182],"parallel":[183],"superiority":[184],"randomized":[185],"control":[186],"trial":[187],"(RCT)":[188],"improving":[190],"lower":[191],"limb":[192],"sensorimotor":[193],"function,":[194],"balance":[195],"&":[196],"quality":[197],"life.":[199],"The":[200,239],"total":[201],"participants":[202],"will":[206,217,241,283],"be":[207,218,242,267,273],"divided":[208],"into":[209],"equal":[211],"groups":[212,226],"then":[214],"intervention":[216,255,271],"given":[219],"8":[221,245],"weeks":[222,246,251],"both":[224],"5":[228],"days":[229],"week":[232],"50":[234],"minute":[235],"session":[236],"each":[237],"day.":[238],"results":[240],"evaluated":[243],"after":[244,252],"treatment":[248],"3":[250],"completion":[253],"follow":[257],"up.":[258],"If":[259],"hypothesis":[261],"our":[263],"proves":[265],"effective,":[268],"this":[269],"physiotherapy":[270],"could":[272],"included":[274],"management":[276],"Along":[279],"it,":[281],"help":[284],"rate":[288],"dose":[293],"due":[294],"neuropathy.":[296]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-10-10T00:00:00"}