{"id":"https://openalex.org/W4416631633","doi":"https://doi.org/10.1128/aem.00983-25","title":"Genetic diversity and phylogenetic characteristics of human adenovirus strains 40/41 circulating in Yantai, China, during 2017\u20132019","display_name":"Genetic diversity and phylogenetic characteristics of human adenovirus strains 40/41 circulating in Yantai, China, during 2017\u20132019","publication_year":2025,"publication_date":"2025-11-25","ids":{"openalex":"https://openalex.org/W4416631633","doi":"https://doi.org/10.1128/aem.00983-25","pmid":"https://pubmed.ncbi.nlm.nih.gov/41288354"},"language":"en","primary_location":{"id":"doi:10.1128/aem.00983-25","doi":"https://doi.org/10.1128/aem.00983-25","is_oa":true,"landing_page_url":"https://doi.org/10.1128/aem.00983-25","pdf_url":null,"source":{"id":"https://openalex.org/S158228368","display_name":"Applied and Environmental Microbiology","issn_l":"0099-2240","issn":["0099-2240","1070-6291","1098-5336"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","medline","norway-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and Environmental Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1128/aem.00983-25","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045195522","display_name":"Peihua Niu","orcid":"https://orcid.org/0000-0001-5930-4234","observed_orcids":["https://orcid.org/0000-0001-5930-4234"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210140986","display_name":"National Institute for Viral Disease Control and Prevention","ror":"https://ror.org/04b1sh213","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210140986","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peihua Niu","raw_affiliation_strings":["National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention","National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0001-5930-4234","affiliations":[{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210140986"]},{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China","institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210140986"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083463864","display_name":"Pengcheng Du","orcid":"https://orcid.org/0000-0002-2930-9920","observed_orcids":["https://orcid.org/0000-0002-2930-9920"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I2800232565","display_name":"Beijing Chao-Yang Hospital, Capital Medical University","ror":"https://ror.org/01eff5662","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800232565","https://openalex.org/I4210110145","https://openalex.org/I4210135108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pengcheng Du","raw_affiliation_strings":["Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University","Qitan Technology Ltd","Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China","Qitan Technology Ltd., Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I2800232565"]},{"raw_affiliation_string":"Qitan Technology Ltd","institution_ids":[]},{"raw_affiliation_string":"Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I2800232565"]},{"raw_affiliation_string":"Qitan Technology Ltd., Chengdu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089220486","display_name":"Zhenlu Sun","orcid":"https://orcid.org/0000-0002-6153-0860","observed_orcids":["https://orcid.org/0000-0002-6153-0860"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhenlu Sun","raw_affiliation_strings":["Yantai Center for Disease Control and Prevention","Yantai Center for Disease Control and Prevention, Yantai, Shandong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yantai Center for Disease Control and Prevention","institution_ids":[]},{"raw_affiliation_string":"Yantai Center for Disease Control and Prevention, Yantai, Shandong, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiuhui Yao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiuhui Yao","raw_affiliation_strings":["Qitan Technology Ltd","Qitan Technology Ltd., Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qitan Technology Ltd","institution_ids":[]},{"raw_affiliation_string":"Qitan Technology Ltd., Chengdu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081334319","display_name":"Yiming Zhao","orcid":"https://orcid.org/0000-0001-5897-9707","observed_orcids":["https://orcid.org/0000-0001-5897-9707"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210140986","display_name":"National Institute for Viral Disease Control and Prevention","ror":"https://ror.org/04b1sh213","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210140986","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiming Zhao","raw_affiliation_strings":["National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention","National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210140986"]},{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China","institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210140986"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100720576","display_name":"Ping Chen","orcid":"https://orcid.org/0000-0002-9940-4528","observed_orcids":["https://orcid.org/0000-0002-9940-4528"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210140986","display_name":"National Institute for Viral Disease Control and Prevention","ror":"https://ror.org/04b1sh213","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210140986","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Cheng","raw_affiliation_strings":["National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention","National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210140986"]},{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China","institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210140986"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079077730","display_name":"Qun Yang","orcid":"https://orcid.org/0000-0002-8507-6287","observed_orcids":["https://orcid.org/0000-0002-8507-6287"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qun Yang","raw_affiliation_strings":["Qitan Technology Ltd","Qitan Technology Ltd., Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qitan Technology Ltd","institution_ids":[]},{"raw_affiliation_string":"Qitan Technology Ltd., Chengdu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zetang Zhang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zetang Zhang","raw_affiliation_strings":["Qitan Technology Ltd","Qitan Technology Ltd., Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qitan Technology Ltd","institution_ids":[]},{"raw_affiliation_string":"Qitan Technology Ltd., Chengdu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107447627","display_name":"Xuejun Ma","orcid":"https://orcid.org/0000-0002-9429-9036","observed_orcids":["https://orcid.org/0000-0002-9429-9036"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210140986","display_name":"National Institute for Viral Disease Control and Prevention","ror":"https://ror.org/04b1sh213","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210140986","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuejun Ma","raw_affiliation_strings":["National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention","National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0002-9429-9036","affiliations":[{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210140986"]},{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China","institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210140986"]}]},{"author_position":"last","author":{"id":null,"display_name":"Ji Wang","orcid":"https://orcid.org/0009-0001-7457-298X","observed_orcids":["https://orcid.org/0009-0001-7457-298X"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210140986","display_name":"National Institute for Viral Disease Control and Prevention","ror":"https://ror.org/04b1sh213","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210140986","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ji Wang","raw_affiliation_strings":["National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention","National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China"],"raw_orcid":"https://orcid.org/0009-0001-7457-298X","affiliations":[{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210140986"]},{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China","institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210140986"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.36823282,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"91","issue":"12","first_page":"e0098325","last_page":"e0098325"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology","score":0.7832000255584717,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology","score":0.7832000255584717,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.09279999881982803,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.02930000051856041,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enteric-adenovirus","display_name":"enteric adenovirus","score":0.7760000228881836},{"id":"https://openalex.org/keywords/acute-gastroenteritis","display_name":"acute gastroenteritis","score":0.9430000185966492},{"id":"https://openalex.org/keywords/genetic-diversity","display_name":"genetic diversity","score":0.7390000224113464},{"id":"https://openalex.org/keywords/phylogenetic-analysis","display_name":"phylogenetic analysis","score":0.8410000205039978},{"id":"https://openalex.org/keywords/recombination","display_name":"recombination","score":0.8050000071525574},{"id":"https://openalex.org/keywords/hexon-gene","display_name":"hexon gene","score":0.859000027179718},{"id":"https://openalex.org/keywords/adaptive-evolution","display_name":"adaptive evolution","score":0.6909999847412109},{"id":"https://openalex.org/keywords/immune-evasion","display_name":"immune evasion","score":0.6919999718666077},{"id":"https://openalex.org/keywords/viral-persistence","display_name":"viral persistence","score":0.597000002861023},{"id":"https://openalex.org/keywords/vaccine-development","display_name":"vaccine development","score":0.6240000128746033},{"id":"https://openalex.org/keywords/shandong","display_name":"Shandong Province","score":0.949999988079071},{"id":"https://openalex.org/keywords/fecal-samples","display_name":"fecal samples","score":0.6029999852180481},{"id":"https://openalex.org/keywords/whole-genome-sequencing","display_name":"whole genome sequencing","score":0.6919999718666077}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8098999857902527},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.6962000131607056},{"id":"https://openalex.org/C81977670","wikidata":"https://www.wikidata.org/wiki/Q585259","display_name":"Genetic diversity","level":3,"score":0.6859999895095825},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5496000051498413},{"id":"https://openalex.org/C8769409","wikidata":"https://www.wikidata.org/wiki/Q2066554","display_name":"Viral evolution","level":4,"score":0.5198000073432922},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.5178999900817871},{"id":"https://openalex.org/C68873052","wikidata":"https://www.wikidata.org/wiki/Q349856","display_name":"Genetic variation","level":3,"score":0.49309998750686646},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.4812999963760376},{"id":"https://openalex.org/C10389963","wikidata":"https://www.wikidata.org/wiki/Q848328","display_name":"Serotype","level":2,"score":0.4781000018119812},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4546000063419342},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4325000047683716},{"id":"https://openalex.org/C171578705","wikidata":"https://www.wikidata.org/wiki/Q5418700","display_name":"Evolutionary dynamics","level":3,"score":0.41749998927116394},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.41679999232292175},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.39329999685287476},{"id":"https://openalex.org/C166393388","wikidata":"https://www.wikidata.org/wiki/Q856529","display_name":"Molecular evolution","level":4,"score":0.39089998602867126},{"id":"https://openalex.org/C40583040","wikidata":"https://www.wikidata.org/wiki/Q1502105","display_name":"Human genetic variation","level":5,"score":0.3799000084400177},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.37869998812675476},{"id":"https://openalex.org/C101434241","wikidata":"https://www.wikidata.org/wiki/Q211675","display_name":"Genetic recombination","level":4,"score":0.3662000000476837},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.3634999990463257},{"id":"https://openalex.org/C156695909","wikidata":"https://www.wikidata.org/wiki/Q3373825","display_name":"Recombination","level":3,"score":0.3465999960899353},{"id":"https://openalex.org/C172777353","wikidata":"https://www.wikidata.org/wiki/Q1374271","display_name":"Genetic variability","level":4,"score":0.3192000091075897},{"id":"https://openalex.org/C167683757","wikidata":"https://www.wikidata.org/wiki/Q5937774","display_name":"Human evolutionary genetics","level":4,"score":0.31220000982284546},{"id":"https://openalex.org/C191942190","wikidata":"https://www.wikidata.org/wiki/Q4774739","display_name":"Antigenic variation","level":3,"score":0.31220000982284546},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.3077999949455261},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.30329999327659607},{"id":"https://openalex.org/C2777046247","wikidata":"https://www.wikidata.org/wiki/Q1907818","display_name":"Mastadenovirus","level":5,"score":0.29919999837875366},{"id":"https://openalex.org/C47042493","wikidata":"https://www.wikidata.org/wiki/Q265799","display_name":"Human genetics","level":3,"score":0.29750001430511475},{"id":"https://openalex.org/C98722961","wikidata":"https://www.wikidata.org/wiki/Q7189436","display_name":"Phylogenetic diversity","level":4,"score":0.2849000096321106},{"id":"https://openalex.org/C2992278830","wikidata":"https://www.wikidata.org/wiki/Q483921","display_name":"Adaptive evolution","level":3,"score":0.28110000491142273},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.27959999442100525},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.2741999924182892},{"id":"https://openalex.org/C98638677","wikidata":"https://www.wikidata.org/wiki/Q2067051","display_name":"Mutation rate","level":3,"score":0.2624000012874603},{"id":"https://openalex.org/C2993967602","wikidata":"https://www.wikidata.org/wiki/Q5532932","display_name":"Genetic variants","level":4,"score":0.2587999999523163},{"id":"https://openalex.org/C57615671","wikidata":"https://www.wikidata.org/wiki/Q5532911","display_name":"Genetic monitoring","level":5,"score":0.2572000026702881},{"id":"https://openalex.org/C190789776","wikidata":"https://www.wikidata.org/wiki/Q767511","display_name":"Genetic marker","level":3,"score":0.25220000743865967}],"mesh":[{"descriptor_ui":"D000258","descriptor_name":"Adenovirus Infections, Human","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D000258","descriptor_name":"Adenovirus Infections, Human","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D000258","descriptor_name":"Adenovirus Infections, Human","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D000258","descriptor_name":"Adenovirus Infections, Human","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D000258","descriptor_name":"Adenovirus Infections, Human","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D000258","descriptor_name":"Adenovirus Infections, Human","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D000258","descriptor_name":"Adenovirus Infections, Human","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D000258","descriptor_name":"Adenovirus Infections, Human","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011995","descriptor_name":"Recombination, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011995","descriptor_name":"Recombination, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011995","descriptor_name":"Recombination, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011995","descriptor_name":"Recombination, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016679","descriptor_name":"Genome, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016679","descriptor_name":"Genome, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016679","descriptor_name":"Genome, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016679","descriptor_name":"Genome, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/aem.00983-25","doi":"https://doi.org/10.1128/aem.00983-25","is_oa":true,"landing_page_url":"https://doi.org/10.1128/aem.00983-25","pdf_url":null,"source":{"id":"https://openalex.org/S158228368","display_name":"Applied and Environmental Microbiology","issn_l":"0099-2240","issn":["0099-2240","1070-6291","1098-5336"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","medline","norway-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and Environmental Microbiology","raw_type":"journal-article"},{"id":"pmid:41288354","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41288354","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and environmental microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:cc9dfb2148864da6988bb7a0569d1e00","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cc9dfb2148864da6988bb7a0569d1e00","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Applied and Environmental Microbiology, Vol 91, Iss 12 (2025)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12724127","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12724127/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Appl Environ Microbiol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1128/aem.00983-25","doi":"https://doi.org/10.1128/aem.00983-25","is_oa":true,"landing_page_url":"https://doi.org/10.1128/aem.00983-25","pdf_url":null,"source":{"id":"https://openalex.org/S158228368","display_name":"Applied and Environmental Microbiology","issn_l":"0099-2240","issn":["0099-2240","1070-6291","1098-5336"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","medline","norway-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and Environmental Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G8579078077","display_name":null,"funder_award_id":"No.2023YFC2306001","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1968305426","https://openalex.org/W2115540209","https://openalex.org/W2161151688","https://openalex.org/W2523696451","https://openalex.org/W3017062089","https://openalex.org/W3048414816","https://openalex.org/W3119167265","https://openalex.org/W3183797711","https://openalex.org/W3197458724","https://openalex.org/W3202419242","https://openalex.org/W4214844855","https://openalex.org/W4283080634","https://openalex.org/W4283788894","https://openalex.org/W4306908090","https://openalex.org/W4360752230","https://openalex.org/W4381548819","https://openalex.org/W4385611127"],"related_works":[],"abstract_inverted_index":{"This":[0],"study":[1],"systematically":[2,267],"characterizes":[3],"the":[4,56,75,101,107,125,140,159,173,187,196,216,224,239,293,311,321,362,375],"genetic":[5,250,308],"diversity,":[6],"phylogenetic":[7,70,294],"relationships,":[8,295],"recombination":[9,78,133,206,296,336],"events,":[10,297],"and":[11,19,29,65,74,82,142,168,190,205,212,223,234,252,288,298,310,326,335,340,349,360,369],"structural":[12,95,299],"variations":[13],"of":[14,33,77,103,127,149,158,193,198,226,243,283,301,313,323,332,357,379],"human":[15],"adenovirus":[16,231],"serotypes":[17,232],"40":[18,233],"41":[20,235],"(HAdV-F40/41)":[21,236],"circulating":[22,271,302],"in":[23,45,113,120,258,272,338],"Shandong":[24,274],"Province,":[25,275],"China,":[26],"between":[27],"2017":[28,277],"2019.":[30,279],"A":[31],"total":[32],"2,221":[34],"stool":[35],"samples":[36,115],"were":[37,49,86],"collected":[38],"from":[39,276],"patients":[40],"presenting":[41],"with":[42,72,117,316],"acute":[43,245],"gastroenteritis":[44,246],"Yantai.":[46],"Enteric":[47],"adenoviruses":[48],"identified":[50,135,163],"using":[51,80],"real-time":[52,284],"quantitative":[53],"PCR":[54],"targeting":[55],"hexon":[57,108,141,339],"gene.":[58],"Whole-genome":[59],"sequencing":[60],"was":[61,97,111],"performed":[62],"via":[63],"nanopore":[64,286],"Illumina":[66],"platforms,":[67],"enabling":[68],"high-resolution":[69],"reconstruction":[71],"IQ-TREE":[73],"identification":[76,331],"events":[79],"RDP5":[81],"SimPlot.":[83],"Evolutionary":[84],"dynamics":[85,254],"inferred":[87],"through":[88],"Bayesian":[89],"molecular":[90,345],"clock":[91],"analysis,":[92],"while":[93,132],"AlphaFold3-based":[94],"modeling":[96,157],"used":[98],"to":[99,172,278,373],"assess":[100],"impact":[102],"genomic":[104,188,200,367],"changes":[105],"on":[106],"protein.":[109],"HAdV-F40/41":[110,269,358],"detected":[112],"94":[114],"(4.23%)":[116],"year-to-year":[118],"variability":[119,309],"prevalence.":[121],"Phylogenetic":[122],"analysis":[123],"revealed":[124],"co-circulation":[126],"multiple":[128],"genetically":[129],"distinct":[130],"lineages,":[131],"mapping":[134],"key":[136,333],"breakpoints,":[137],"notably":[138],"within":[139],"pVII":[143,341],"genes.":[144],"The":[145,202,330],"estimated":[146],"recent":[147],"divergence":[148],"dominant":[150],"lineages":[151,315],"suggests":[152],"ongoing":[153],"adaptive":[154,324],"evolution.":[155],"Structural":[156],"recombinant":[160,314],"strain":[161,175],"SD376":[162],"14":[164],"amino":[165],"acid":[166],"substitutions":[167],"three":[169],"deletions":[170],"relative":[171],"reference":[174],"OP378826.1,":[176],"without":[177],"substantial":[178],"conformational":[179],"alteration.":[180],"These":[181,352],"findings":[182,353],"provide":[183],"critical":[184],"insights":[185],"into":[186],"plasticity":[189],"evolutionary":[191,253],"potential":[192,327],"HAdV-F40/41,":[194],"underscoring":[195,320],"importance":[197],"continuous":[199,366],"surveillance.":[201],"observed":[203],"mutations":[204,334],"patterns":[207],"may":[208],"facilitate":[209],"immune":[210,328],"escape":[211],"viral":[213,241],"persistence,":[214],"reinforcing":[215],"urgent":[217,363],"need":[218,364],"for":[219,347,365],"improved":[220],"monitoring":[221,368],"strategies":[222],"development":[225,372],"targeted":[227,370],"vaccines.":[228],"IMPORTANCE:":[229],"Human":[230],"are":[237],"among":[238],"leading":[240],"causes":[242],"pediatric":[244],"worldwide,":[247],"yet":[248],"their":[249],"diversity":[251],"remain":[255],"poorly":[256],"characterized":[257],"many":[259],"regions,":[260],"including":[261],"China.":[262],"In":[263],"this":[264],"study,":[265],"we":[266,291],"investigated":[268],"strains":[270],"Yantai,":[273],"Using":[280],"a":[281],"combination":[282],"PCR,":[285],"sequencing,":[287,290],"next-generation":[289],"elucidated":[292],"features":[300],"strains.":[303],"Our":[304],"results":[305],"reveal":[306],"extensive":[307],"emergence":[312],"altered":[317],"antigenic":[318],"profiles,":[319],"role":[322],"evolution":[325,359],"escape.":[329],"hotspots":[337],"genes":[342],"provides":[343],"important":[344],"markers":[346],"surveillance":[348],"risk":[350],"assessment.":[351],"enhance":[354],"our":[355],"understanding":[356],"highlight":[361],"vaccine":[371],"mitigate":[374],"public":[376],"health":[377],"burden":[378],"adenoviral":[380],"gastroenteritis.":[381]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2025-11-25T00:00:00"}