{"id":"https://openalex.org/W4416630182","doi":"https://doi.org/10.1186/s40337-025-01454-0","title":"From shared mechanisms to treatment gaps: a review of the comorbidity between eating disorders and PTSD","display_name":"From shared mechanisms to treatment gaps: a review of the comorbidity between eating disorders and PTSD","publication_year":2025,"publication_date":"2025-11-25","ids":{"openalex":"https://openalex.org/W4416630182","doi":"https://doi.org/10.1186/s40337-025-01454-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/41291932"},"language":"en","primary_location":{"id":"doi:10.1186/s40337-025-01454-0","doi":"https://doi.org/10.1186/s40337-025-01454-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40337-025-01454-0","pdf_url":"https://link.springer.com/content/pdf/10.1186/s40337-025-01454-0.pdf","source":{"id":"https://openalex.org/S4210234357","display_name":"Journal of Eating Disorders","issn_l":"2050-2974","issn":["2050-2974"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Eating Disorders","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s40337-025-01454-0.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006345290","display_name":"Hanlai Ouyang","orcid":"https://orcid.org/0009-0003-1797-6894","observed_orcids":["https://orcid.org/0009-0003-1797-6894"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hanlai Ouyang","raw_affiliation_strings":["Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine and School of Psychology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine and School of Psychology, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102838052","display_name":"Yating Wang","orcid":"https://orcid.org/0009-0007-7127-4825","observed_orcids":["https://orcid.org/0009-0007-7127-4825"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yating Wang","raw_affiliation_strings":["Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine and School of Psychology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine and School of Psychology, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100686866","display_name":"Jue Chen","orcid":"https://orcid.org/0000-0002-9924-2573","observed_orcids":["https://orcid.org/0000-0002-9924-2573"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jue Chen","raw_affiliation_strings":["Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine and School of Psychology, Shanghai, China. chenjue2088@163.com","Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine and School of Psychology, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0002-9924-2573","affiliations":[{"raw_affiliation_string":"Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine and School of Psychology, Shanghai, China. chenjue2088@163.com","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]},{"raw_affiliation_string":"Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine and School of Psychology, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100686866"],"corresponding_institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"],"apc_list":{"value":2190,"currency":"USD","value_usd":2190},"apc_paid":{"value":2190,"currency":"USD","value_usd":2190},"fwci":5.876,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.96412539,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"13","issue":"1","first_page":"271","last_page":"271"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10263","display_name":"Eating Disorders and Behaviors","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10263","display_name":"Eating Disorders and Behaviors","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10242","display_name":"Posttraumatic Stress Disorder Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11093","display_name":"Personality Disorders and Psychopathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eating-disorders","display_name":"eating disorders","score":0.9769999980926514},{"id":"https://openalex.org/keywords/posttraumatic-stress-disorder","display_name":"post-traumatic stress disorder","score":0.9890000224113464},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.925000011920929},{"id":"https://openalex.org/keywords/anorexia-nervosa","display_name":"anorexia nervosa","score":0.9850000143051147},{"id":"https://openalex.org/keywords/bulimia-nervosa","display_name":"bulimia nervosa","score":1.0},{"id":"https://openalex.org/keywords/binge-eating-disorder","display_name":"binge eating disorder","score":0.9900000095367432},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.9039999842643738},{"id":"https://openalex.org/keywords/immune-system-alterations","display_name":"immune system alterations","score":0.7269999980926514},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9940000176429749},{"id":"https://openalex.org/keywords/emotion-dysregulation","display_name":"emotional dysregulation","score":0.9959999918937683},{"id":"https://openalex.org/keywords/dissociation","display_name":"dissociation","score":1.0},{"id":"https://openalex.org/keywords/trauma-informed-care","display_name":"trauma-informed care","score":0.8899999856948853},{"id":"https://openalex.org/keywords/treatment-gap","display_name":"treatment gap","score":0.6600000262260437},{"id":"https://openalex.org/keywords/treatment-discontinuation","display_name":"treatment discontinuation","score":0.5640000104904175}],"concepts":[{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.7688000202178955},{"id":"https://openalex.org/C2776394216","wikidata":"https://www.wikidata.org/wiki/Q373822","display_name":"Eating disorders","level":2,"score":0.6455000042915344},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.6031000018119812},{"id":"https://openalex.org/C2778202721","wikidata":"https://www.wikidata.org/wiki/Q209522","display_name":"Binge-eating disorder","level":4,"score":0.5446000099182129},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5410000085830688},{"id":"https://openalex.org/C2778654693","wikidata":"https://www.wikidata.org/wiki/Q254327","display_name":"Anorexia","level":2,"score":0.5360000133514404},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.5292999744415283},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5002999901771545},{"id":"https://openalex.org/C2781426410","wikidata":"https://www.wikidata.org/wiki/Q2303219","display_name":"Binge eating","level":3,"score":0.4912000000476837},{"id":"https://openalex.org/C2777031586","wikidata":"https://www.wikidata.org/wiki/Q131749","display_name":"Anorexia nervosa","level":3,"score":0.47589999437332153},{"id":"https://openalex.org/C3018243667","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Psychiatric comorbidity","level":3,"score":0.4494999945163727},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.40299999713897705},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.39419999718666077},{"id":"https://openalex.org/C2777556793","wikidata":"https://www.wikidata.org/wiki/Q64513386","display_name":"Bulimia nervosa","level":3,"score":0.38999998569488525},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3635999858379364},{"id":"https://openalex.org/C2781265626","wikidata":"https://www.wikidata.org/wiki/Q1147152","display_name":"Cognitive behavioral therapy","level":3,"score":0.3215000033378601},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.31520000100135803},{"id":"https://openalex.org/C2776035688","wikidata":"https://www.wikidata.org/wiki/Q1606558","display_name":"Affect (linguistics)","level":2,"score":0.314300000667572},{"id":"https://openalex.org/C2776145597","wikidata":"https://www.wikidata.org/wiki/Q25339462","display_name":"Dropout (neural networks)","level":2,"score":0.2971999943256378},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.28130000829696655},{"id":"https://openalex.org/C2778794976","wikidata":"https://www.wikidata.org/wiki/Q3316140","display_name":"Emotional dysregulation","level":2,"score":0.26919999718666077}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1186/s40337-025-01454-0","doi":"https://doi.org/10.1186/s40337-025-01454-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40337-025-01454-0","pdf_url":"https://link.springer.com/content/pdf/10.1186/s40337-025-01454-0.pdf","source":{"id":"https://openalex.org/S4210234357","display_name":"Journal of Eating Disorders","issn_l":"2050-2974","issn":["2050-2974"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Eating Disorders","raw_type":"journal-article"},{"id":"pmid:41291932","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41291932","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of eating disorders","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:042358b9b04c4700bded8ee65b845845","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/042358b9b04c4700bded8ee65b845845","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Eating Disorders, Vol 13, Iss 1, Pp 1-15 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s40337-025-01454-0","doi":"https://doi.org/10.1186/s40337-025-01454-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40337-025-01454-0","pdf_url":"https://link.springer.com/content/pdf/10.1186/s40337-025-01454-0.pdf","source":{"id":"https://openalex.org/S4210234357","display_name":"Journal of Eating Disorders","issn_l":"2050-2974","issn":["2050-2974"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Eating Disorders","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G8753278078","display_name":null,"funder_award_id":"82471573","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320325338","display_name":"Shanghai Hospital Development Center","ror":"https://ror.org/02zrtve16"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4416630182.pdf","grobid_xml":"https://content.openalex.org/works/W4416630182.grobid-xml"},"referenced_works_count":168,"referenced_works":["https://openalex.org/W321783900","https://openalex.org/W1497134717","https://openalex.org/W1543244495","https://openalex.org/W1671090260","https://openalex.org/W1776233564","https://openalex.org/W1806666425","https://openalex.org/W1834689222","https://openalex.org/W1950113474","https://openalex.org/W1972599083","https://openalex.org/W1972883514","https://openalex.org/W1976707838","https://openalex.org/W1978911881","https://openalex.org/W1982192746","https://openalex.org/W1989618975","https://openalex.org/W2017539313","https://openalex.org/W2022032719","https://openalex.org/W2026003300","https://openalex.org/W2026836897","https://openalex.org/W2027660519","https://openalex.org/W2041199817","https://openalex.org/W2056793125","https://openalex.org/W2063273990","https://openalex.org/W2067689880","https://openalex.org/W2070843702","https://openalex.org/W2073681226","https://openalex.org/W2077122683","https://openalex.org/W2088519055","https://openalex.org/W2091886883","https://openalex.org/W2096282728","https://openalex.org/W2102097620","https://openalex.org/W2126768661","https://openalex.org/W2126841876","https://openalex.org/W2144791813","https://openalex.org/W2155573052","https://openalex.org/W2158809703","https://openalex.org/W2164086669","https://openalex.org/W2179430669","https://openalex.org/W2257303989","https://openalex.org/W2270584696","https://openalex.org/W2293765053","https://openalex.org/W2315196237","https://openalex.org/W2395299385","https://openalex.org/W2419174289","https://openalex.org/W2492978898","https://openalex.org/W2534253241","https://openalex.org/W2541690515","https://openalex.org/W2542484505","https://openalex.org/W2578935374","https://openalex.org/W2587109974","https://openalex.org/W2590245531","https://openalex.org/W2594295003","https://openalex.org/W2605653556","https://openalex.org/W2687532560","https://openalex.org/W2734898627","https://openalex.org/W2749796049","https://openalex.org/W2751434469","https://openalex.org/W2753598504","https://openalex.org/W2799377683","https://openalex.org/W2799558144","https://openalex.org/W2808836043","https://openalex.org/W2809244390","https://openalex.org/W2886870206","https://openalex.org/W2886986905","https://openalex.org/W2887022365","https://openalex.org/W2894863765","https://openalex.org/W2895011038","https://openalex.org/W2896188958","https://openalex.org/W2896729901","https://openalex.org/W2903702266","https://openalex.org/W2905436628","https://openalex.org/W2910452524","https://openalex.org/W2914925950","https://openalex.org/W2925785232","https://openalex.org/W2938312849","https://openalex.org/W2945891876","https://openalex.org/W2964802109","https://openalex.org/W2970622816","https://openalex.org/W2973142894","https://openalex.org/W2980539977","https://openalex.org/W2989824998","https://openalex.org/W3003924712","https://openalex.org/W3006076039","https://openalex.org/W3008204058","https://openalex.org/W3008346751","https://openalex.org/W3010737831","https://openalex.org/W3012313023","https://openalex.org/W3017016408","https://openalex.org/W3021468712","https://openalex.org/W3049754613","https://openalex.org/W3082793248","https://openalex.org/W3087712817","https://openalex.org/W3094688337","https://openalex.org/W3101149835","https://openalex.org/W3111509171","https://openalex.org/W3112464669","https://openalex.org/W3113853648","https://openalex.org/W3119216517","https://openalex.org/W3128984844","https://openalex.org/W3132273857","https://openalex.org/W3135291985","https://openalex.org/W3135843262","https://openalex.org/W3140339595","https://openalex.org/W3162809902","https://openalex.org/W3164626508","https://openalex.org/W3188211301","https://openalex.org/W3195156262","https://openalex.org/W3196687877","https://openalex.org/W3212642355","https://openalex.org/W4200192096","https://openalex.org/W4205768077","https://openalex.org/W4206213217","https://openalex.org/W4210956615","https://openalex.org/W4211189621","https://openalex.org/W4220888739","https://openalex.org/W4248533626","https://openalex.org/W4281787231","https://openalex.org/W4283020467","https://openalex.org/W4283167032","https://openalex.org/W4283360625","https://openalex.org/W4283747509","https://openalex.org/W4290644619","https://openalex.org/W4292425764","https://openalex.org/W4294956098","https://openalex.org/W4296381367","https://openalex.org/W4306176327","https://openalex.org/W4308735496","https://openalex.org/W4308899803","https://openalex.org/W4308930923","https://openalex.org/W4309578308","https://openalex.org/W4322422753","https://openalex.org/W4324130224","https://openalex.org/W4360584587","https://openalex.org/W4361018004","https://openalex.org/W4362456492","https://openalex.org/W4362506971","https://openalex.org/W4362662661","https://openalex.org/W4366162803","https://openalex.org/W4372294432","https://openalex.org/W4376279493","https://openalex.org/W4383681920","https://openalex.org/W4385283313","https://openalex.org/W4385986371","https://openalex.org/W4386507877","https://openalex.org/W4387307675","https://openalex.org/W4388035041","https://openalex.org/W4391389600","https://openalex.org/W4391754533","https://openalex.org/W4392192831","https://openalex.org/W4392513509","https://openalex.org/W4394959302","https://openalex.org/W4396778155","https://openalex.org/W4398218565","https://openalex.org/W4400225364","https://openalex.org/W4401477000","https://openalex.org/W4401960906","https://openalex.org/W4402343721","https://openalex.org/W4402616347","https://openalex.org/W4403989383","https://openalex.org/W4404821376","https://openalex.org/W4406115557","https://openalex.org/W4406338182","https://openalex.org/W4407627370","https://openalex.org/W4407731264","https://openalex.org/W4409140261","https://openalex.org/W4409244008","https://openalex.org/W4410282435","https://openalex.org/W4410748059","https://openalex.org/W4411968451"],"related_works":[],"abstract_inverted_index":{"Eating":[0,160],"disorders":[1,189,280],"(EDs),":[2],"including":[3,106],"anorexia":[4,164],"nervosa,":[5,7,165,167],"bulimia":[6,166],"and":[8,21,42,44,78,90,120,158,168,179,193,220,229,238,260,281,306,323,352],"binge":[9],"eating":[10,19,188,227,279],"disorder,":[11,170],"are":[12,125,171,252],"severe":[13,68],"psychiatric":[14],"illnesses":[15,174],"marked":[16],"by":[17,35,152],"disordered":[18],"patterns":[20],"psychological":[22,91,180],"disturbances.":[23],"Post-traumatic":[24],"stress":[25,200],"disorder":[26,201,228],"(PTSD),":[27],"a":[28,103,263],"common":[29,276],"response":[30],"to":[31,146,197,207,255,313,349],"trauma,":[32,192],"is":[33,50,64,138],"characterized":[34],"re-experiencing,":[36],"avoidance,":[37],"negative":[38],"alterations":[39],"in":[40,58,298,303,308],"cognition":[41],"mood,":[43],"hyperarousal.":[45],"The":[46],"prevalence":[47],"of":[48,84,108,130,156,185,218,258,278,328,354],"PTSD":[49,203,230],"significantly":[51],"higher":[52,74],"among":[53],"individuals":[54,150],"with":[55,66,187,244,287],"EDs":[56,157],"than":[57],"the":[59,87,109,128,153,209,271,275,288,299,320,326,336,342],"general":[60],"population.":[61,136,359],"This":[62,96,268],"comorbidity":[63],"associated":[65],"more":[67,249,253],"clinical":[69,132],"presentations,":[70],"greater":[71],"functional":[72],"impairment,":[73],"treatment":[75,123],"dropout":[76],"rates,":[77],"poorer":[79],"prognoses.":[80],"Despite":[81],"increasing":[82],"recognition":[83],"this":[85,135,314,357],"co-occurrence,":[86],"underlying":[88],"biological":[89],"mechanisms":[92],"remain":[93],"inadequately":[94],"understood.":[95],"review":[97,269],"explores":[98,270],"potential":[99],"shared":[100],"pathways":[101],"from":[102],"biopsychological":[104],"perspective,":[105],"dysregulation":[107],"hypothalamic-pituitary-adrenal":[110],"axis,":[111,292],"immune":[112,300],"system":[113],"alterations,":[114],"gut":[115,304],"microbiota":[116],"imbalances,":[117],"emotional":[118],"dysregulation,":[119],"dissociation.":[121],"Current":[122],"strategies":[124],"reviewed,":[126],"highlighting":[127],"lack":[129,327],"specific":[131],"guidelines":[133,330],"for":[134,142,149,331,345,356],"There":[137],"an":[139,226],"urgent":[140,343],"need":[141,344],"integrated,":[143],"trauma-informed":[144],"interventions":[145],"enhance":[147],"outcomes":[148],"affected":[151],"dual":[154],"burden":[155],"PTSD.":[159,282],"disorders,":[161],"such":[162],"as":[163],"binge-eating":[169],"serious":[172],"mental":[173],"that":[175,215],"harm":[176],"both":[177,245,333],"physical":[178],"health.":[181],"A":[182],"substantial":[183],"proportion":[184],"people":[186,206],"have":[190,248,262],"experienced":[191],"many":[194],"go":[195],"on":[196,223],"develop":[198],"post-traumatic":[199],"(PTSD).":[202],"can":[204],"cause":[205],"relive":[208],"trauma":[210],"through":[211],"flashbacks,":[212],"avoid":[213],"anything":[214],"reminds":[216],"them":[217],"it,":[219],"feel":[221],"constantly":[222],"edge.":[224],"When":[225],"occur":[231],"together,":[232],"they":[233],"make":[234],"each":[235],"other":[236],"worse":[237],"recovery":[239,351],"much":[240],"harder.":[241],"People":[242],"struggling":[243],"conditions":[246,334],"often":[247],"intense":[250],"symptoms,":[251],"likely":[254],"drop":[256],"out":[257,325],"treatment,":[259],"generally":[261],"tougher":[264],"time":[265],"getting":[266],"better.":[267],"possible":[272],"reasons":[273],"behind":[274],"co-occurrence":[277],"We":[283,316],"discuss":[284],"how":[285],"problems":[286],"HPA":[289],"axis":[290],"(hypothalamic-pituitary-adrenal":[291],"our":[293],"body\u2019s":[294],"stress-response":[295],"system),":[296],"changes":[297],"system,":[301],"imbalances":[302],"health,":[305],"difficulties":[307],"managing":[309],"emotions":[310],"may":[311],"contribute":[312],"connection.":[315],"also":[317],"look":[318],"at":[319,335],"current":[321],"treatments":[322,348],"point":[324],"clear":[329],"treating":[332],"same":[337],"time.":[338],"Our":[339],"findings":[340],"highlight":[341],"combined,":[346],"trauma-sensitive":[347],"improve":[350],"quality":[353],"life":[355],"vulnerable":[358]},"counts_by_year":[{"year":2026,"cited_by_count":5}],"updated_date":"2026-10-03T13:16:28.481748","created_date":"2025-11-25T00:00:00"}
