{"id":"https://openalex.org/W4416628107","doi":"https://doi.org/10.5256/f1000research.148326.r180684","title":"Peer Review Report For: New insight on antioxidants and anti-obesity properties of two Indonesian seagrass Thalassia hemprichii and Zostera marina: an integrated molecular docking simulation with in vitro study [version 1; peer review: 2 approved with reservations]","display_name":"Peer Review Report For: New insight on antioxidants and anti-obesity properties of two Indonesian seagrass Thalassia hemprichii and Zostera marina: an integrated molecular docking simulation with in vitro study [version 1; peer review: 2 approved with reservations]","publication_year":2023,"publication_date":"2023-07-06","ids":{"openalex":"https://openalex.org/W4416628107","doi":"https://doi.org/10.5256/f1000research.148326.r180684"},"language":"en","primary_location":{"id":"doi:10.5256/f1000research.148326.r180684","doi":"https://doi.org/10.5256/f1000research.148326.r180684","is_oa":true,"landing_page_url":"https://doi.org/10.5256/f1000research.148326.r180684","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zagazig University","raw_type":"peer-review"},"volume":null,"type":"peer-review","indexed_in":["crossref","datacite"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.5256/f1000research.148326.r180684","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022362387","display_name":"Billy Th. Wagey","orcid":"https://orcid.org/0000-0003-4350-8683","observed_orcids":["https://orcid.org/0000-0003-4350-8683","https://orcid.org/0000-0002-7059-8701"]},"institutions":[{"id":"https://openalex.org/I55214057","display_name":"Sam Ratulangi University","ror":"https://ror.org/01cn6ph21","country_code":"ID","type":"education","lineage":["https://openalex.org/I55214057"]}],"countries":["ID"],"is_corresponding":true,"raw_author_name":"Billy Theodorus Wagey","raw_affiliation_strings":["Marine Sciences Study Program, Faculty of Fisheries and Marine Sciences, Sam Ratulangi University, Manado, 95115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Sciences Study Program, Faculty of Fisheries and Marine Sciences, Sam Ratulangi University, Manado, 95115","institution_ids":["https://openalex.org/I55214057"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055802547","display_name":"William Ben Gunawan","orcid":"https://orcid.org/0000-0003-0633-4477","observed_orcids":["https://orcid.org/0000-0003-0633-4477"]},"institutions":[{"id":"https://openalex.org/I11855966","display_name":"Diponegoro University","ror":"https://ror.org/056bjta22","country_code":"ID","type":"education","lineage":["https://openalex.org/I11855966"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"William Ben Gunawan","raw_affiliation_strings":["Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang, 50275"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang, 50275","institution_ids":["https://openalex.org/I11855966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028154311","display_name":"Ridwan Lasabuda","orcid":"https://orcid.org/0000-0002-4122-8103","observed_orcids":["https://orcid.org/0000-0002-4122-8103"]},"institutions":[{"id":"https://openalex.org/I55214057","display_name":"Sam Ratulangi University","ror":"https://ror.org/01cn6ph21","country_code":"ID","type":"education","lineage":["https://openalex.org/I55214057"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Ridwan Lasabuda","raw_affiliation_strings":["Marine Sciences Study Program, Faculty of Fisheries and Marine Sciences, Sam Ratulangi University, Manado, 95115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Sciences Study Program, Faculty of Fisheries and Marine Sciences, Sam Ratulangi University, Manado, 95115","institution_ids":["https://openalex.org/I55214057"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147867047","display_name":"Nelly Mayulu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405270787","display_name":"Universitas Muhammadiyah Manado","ror":"https://ror.org/01av3sb15","country_code":"ID","type":"education","lineage":["https://openalex.org/I4405270787"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Nelly Mayulu","raw_affiliation_strings":["Department of Nutrition, Universitas Muhammadiyah Manado, Manado, North Sulawesi, 95115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Universitas Muhammadiyah Manado, Manado, North Sulawesi, 95115","institution_ids":["https://openalex.org/I4405270787"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024888505","display_name":"Msy Firyal Nadya Al Mahira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177055848","display_name":"University of Brawijaya","ror":"https://ror.org/01wk3d929","country_code":"ID","type":"education","lineage":["https://openalex.org/I177055848"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Msy Firyal Nadya Al Mahira","raw_affiliation_strings":["Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145","institution_ids":["https://openalex.org/I177055848"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027775221","display_name":"Deogifta Graciani Lailossa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177055848","display_name":"University of Brawijaya","ror":"https://ror.org/01wk3d929","country_code":"ID","type":"education","lineage":["https://openalex.org/I177055848"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Deogifta Graciani Lailossa","raw_affiliation_strings":["Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145","institution_ids":["https://openalex.org/I177055848"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092228228","display_name":"Fitra Riswanda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177055848","display_name":"University of Brawijaya","ror":"https://ror.org/01wk3d929","country_code":"ID","type":"education","lineage":["https://openalex.org/I177055848"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Fitra Riswanda","raw_affiliation_strings":["Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145","institution_ids":["https://openalex.org/I177055848"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092228229","display_name":"Elizabeth Levyna Berta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177055848","display_name":"University of Brawijaya","ror":"https://ror.org/01wk3d929","country_code":"ID","type":"education","lineage":["https://openalex.org/I177055848"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Elizabeth Levyna Berta","raw_affiliation_strings":["Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145","institution_ids":["https://openalex.org/I177055848"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092228230","display_name":"Putra Mahakarya Dewa","orcid":"https://orcid.org/0009-0009-0542-5941","observed_orcids":["https://orcid.org/0009-0009-0542-5941"]},"institutions":[{"id":"https://openalex.org/I177055848","display_name":"University of Brawijaya","ror":"https://ror.org/01wk3d929","country_code":"ID","type":"education","lineage":["https://openalex.org/I177055848"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Putra Mahakarya Dewa","raw_affiliation_strings":["Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145","institution_ids":["https://openalex.org/I177055848"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027028385","display_name":"Dewangga Yudisthira","orcid":"https://orcid.org/0000-0002-3317-1602","observed_orcids":["https://orcid.org/0000-0002-3317-1602"]},"institutions":[{"id":"https://openalex.org/I177055848","display_name":"University of Brawijaya","ror":"https://ror.org/01wk3d929","country_code":"ID","type":"education","lineage":["https://openalex.org/I177055848"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Dewangga Yudisthira","raw_affiliation_strings":["Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical School Department, Faculty of Medicine, Brawijaya University, Malang, 65145","institution_ids":["https://openalex.org/I177055848"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045435264","display_name":"Darmawan Alisaputra","orcid":"https://orcid.org/0000-0001-5007-5404","observed_orcids":["https://orcid.org/0000-0001-5007-5404"]},"institutions":[{"id":"https://openalex.org/I181085462","display_name":"Sunan Kalijaga State Islamic University Yogyakarta","ror":"https://ror.org/00nmvbd84","country_code":"ID","type":"education","lineage":["https://openalex.org/I181085462"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Darmawan Alisaputra","raw_affiliation_strings":["Department of Chemistry, State Islamic University of Sunan Kalijaga (UIN Sunan Kalijaga), Yogyakarta, 55281"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, State Islamic University of Sunan Kalijaga (UIN Sunan Kalijaga), Yogyakarta, 55281","institution_ids":["https://openalex.org/I181085462"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083083319","display_name":"Astri Arnamalia","orcid":"https://orcid.org/0009-0007-4005-0132","observed_orcids":["https://orcid.org/0009-0007-4005-0132"]},"institutions":[{"id":"https://openalex.org/I181085462","display_name":"Sunan Kalijaga State Islamic University Yogyakarta","ror":"https://ror.org/00nmvbd84","country_code":"ID","type":"education","lineage":["https://openalex.org/I181085462"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Astri Arnamalia","raw_affiliation_strings":["Department of Chemistry, State Islamic University of Sunan Kalijaga (UIN Sunan Kalijaga), Yogyakarta, 55281"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, State Islamic University of Sunan Kalijaga (UIN Sunan Kalijaga), Yogyakarta, 55281","institution_ids":["https://openalex.org/I181085462"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029757746","display_name":"Nindy Sabrina","orcid":"https://orcid.org/0000-0003-3777-4563","observed_orcids":["https://orcid.org/0000-0003-3777-4563"]},"institutions":[{"id":"https://openalex.org/I4210156875","display_name":"Universitas Sahid Jakarta","ror":"https://ror.org/05x9hft88","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210156875"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Nindy Sabrina","raw_affiliation_strings":["Nutrition Program, Faculty of Food Technology and Health, Sahid University of Jakarta, South Jakarta"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nutrition Program, Faculty of Food Technology and Health, Sahid University of Jakarta, South Jakarta","institution_ids":["https://openalex.org/I4210156875"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008884512","display_name":"Nurpudji Astuti Taslim","orcid":"https://orcid.org/0000-0003-1349-5367","observed_orcids":["https://orcid.org/0000-0003-1349-5367"]},"institutions":[{"id":"https://openalex.org/I98301867","display_name":"Hasanuddin University","ror":"https://ror.org/00da1gf19","country_code":"ID","type":"education","lineage":["https://openalex.org/I98301867"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Nurpudji Astuti Taslim","raw_affiliation_strings":["Division of Clinical Nutrition, Department of Nutrition, Faculty of Medicine, Hasanuddin University, Makassar, 90245"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Nutrition, Department of Nutrition, Faculty of Medicine, Hasanuddin University, Makassar, 90245","institution_ids":["https://openalex.org/I98301867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092228227","display_name":"Clarin Hayes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126826664","display_name":"Udayana University","ror":"https://ror.org/035qsg823","country_code":"ID","type":"education","lineage":["https://openalex.org/I126826664"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Clarin Hayes","raw_affiliation_strings":["Biomedical Science Master Program, Faculty of Medicine, Udayana University, Badung, 80361"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Science Master Program, Faculty of Medicine, Udayana University, Badung, 80361","institution_ids":["https://openalex.org/I126826664"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034601041","display_name":"Fahrul Nurkolis","orcid":"https://orcid.org/0000-0003-2151-0854","observed_orcids":["https://orcid.org/0000-0003-2151-0854"]},"institutions":[{"id":"https://openalex.org/I181085462","display_name":"Sunan Kalijaga State Islamic University Yogyakarta","ror":"https://ror.org/00nmvbd84","country_code":"ID","type":"education","lineage":["https://openalex.org/I181085462"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Fahrul Nurkolis","raw_affiliation_strings":["Department of Biological Sciences, State Islamic University of Sunan Kalijaga (UIN Sunan Kalijaga), Yogyakarta, 55281"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, State Islamic University of Sunan Kalijaga (UIN Sunan Kalijaga), Yogyakarta, 55281","institution_ids":["https://openalex.org/I181085462"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5022362387"],"corresponding_institution_ids":["https://openalex.org/I55214057"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11390","display_name":"Seaweed-derived Bioactive Compounds","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11390","display_name":"Seaweed-derived Bioactive Compounds","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10643","display_name":"Marine and coastal plant biology","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1910","display_name":"Oceanography"},"field":{"id":"https://openalex.org/fields/19","display_name":"Earth and Planetary Sciences"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thalassia-hemprichii","display_name":"Thalassia hemprichii","score":0.9649999737739563},{"id":"https://openalex.org/keywords/zostera-marina","display_name":"Zostera marina","score":1.0},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.8669999837875366},{"id":"https://openalex.org/keywords/anti-obesity-effect","display_name":"anti-obesity","score":0.8700000047683716},{"id":"https://openalex.org/keywords/inducible-nitric-oxide-synthase-inhibition","display_name":"inducible nitric oxide synthase inhibition","score":0.8889999985694885},{"id":"https://openalex.org/keywords/pancreatic-lipase-inhibition","display_name":"pancreatic lipase inhibition","score":0.9850000143051147},{"id":"https://openalex.org/keywords/luteolin","display_name":"luteolin","score":0.8460000157356262},{"id":"https://openalex.org/keywords/kaempferol","display_name":"kaempferol","score":0.7860000133514404},{"id":"https://openalex.org/keywords/apigenin","display_name":"apigenin","score":0.7710000276565552},{"id":"https://openalex.org/keywords/diosmetin","display_name":"diosmetin","score":0.9160000085830688},{"id":"https://openalex.org/keywords/abts-assay","display_name":"ABTS radical scavenging","score":0.8930000066757202},{"id":"https://openalex.org/keywords/untargeted-metabolomics","display_name":"untargeted metabolomics","score":0.6990000009536743},{"id":"https://openalex.org/keywords/functional-foods","display_name":"functional foods","score":0.6930000185966492}],"concepts":[{"id":"https://openalex.org/C2777400808","wikidata":"https://www.wikidata.org/wiki/Q646660","display_name":"Seagrass","level":3,"score":0.7447999715805054},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6039000153541565},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.3549000024795532},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.3521000146865845},{"id":"https://openalex.org/C2779207338","wikidata":"https://www.wikidata.org/wiki/Q9240","display_name":"Indonesian","level":2,"score":0.3433000147342682},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.30799999833106995},{"id":"https://openalex.org/C2776308701","wikidata":"https://www.wikidata.org/wiki/Q3519445","display_name":"Thalassia testudinum","level":4,"score":0.2678000032901764},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.26019999384880066},{"id":"https://openalex.org/C2780695071","wikidata":"https://www.wikidata.org/wiki/Q21128","display_name":"Zostera marina","level":4,"score":0.25929999351501465},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.24400000274181366}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.5256/f1000research.148326.r180684","doi":"https://doi.org/10.5256/f1000research.148326.r180684","is_oa":true,"landing_page_url":"https://doi.org/10.5256/f1000research.148326.r180684","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zagazig University","raw_type":"peer-review"},{"id":"doi:10.5256/f1000research.148326.r180684","doi":"https://doi.org/10.5256/f1000research.148326.r180684","is_oa":true,"landing_page_url":"https://doi.org/10.5256/f1000research.148326.r180684","pdf_url":null,"source":{"id":"https://openalex.org/S7407050752","display_name":"Faculty of 1000 Research Ltd","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.5256/f1000research.148326.r180684","doi":"https://doi.org/10.5256/f1000research.148326.r180684","is_oa":true,"landing_page_url":"https://doi.org/10.5256/f1000research.148326.r180684","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zagazig University","raw_type":"peer-review"},"sustainable_development_goals":[{"display_name":"Life below water","id":"https://metadata.un.org/sdg/14","score":1.0},{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7246000170707703}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Background":[0],":":[1,258],"The":[2],"oceans":[3],"are":[4],"teeming":[5],"with":[6,92],"a":[7,224],"diverse":[8],"range":[9],"of":[10,24,47,72,141,159,168,221,239],"marine":[11,27],"organisms":[12],"that":[13,29,261],"offer":[14],"unique":[15],"health":[16],"benefits,":[17],"such":[18],"as":[19,166,270],"seagrass":[20],"which":[21,245],"is":[22],"one":[23],"many":[25],"key":[26],"products":[28],"have":[30,42,163,266],"garnered":[31],"attention":[32],"for":[33,272],"their":[34],"potential":[35,67,165],"therapeutic":[36],"properties.":[37],"However,":[38],"until":[39],"now":[40],"there":[41],"been":[43],"few":[44],"successful":[45],"reports":[46],"seagrass\u2019s":[48],"metabolites":[49,60,145],"profile":[50,59],"and":[51,64,69,78,87,98,120,123,131,143,151,154,183,186,203,234,281],"biological":[52,268],"activity.":[53],"Therefore,":[54],"this":[55],"work":[56],"aims":[57],"to":[58,113],"or":[61],"chemical":[62],"constituents":[63],"assess":[65],"the":[66,160,247,262],"antioxidants":[68],"anti-obesity":[70,124],"effects":[71],"two":[73,93,263],"Indonesian":[74,264],"seagrasses,":[75],"Thalassia":[76],"hemprichii":[77,86,150,206],"Zostera":[79],"marina":[80,89,153],".":[81],"Methods:":[82],"Once":[83],"authenticated,":[84],"T.":[85,149,205],"Z.":[88,152],"were":[90,126,146],"extracted":[91],"different":[94],"solvents,":[95],"polar":[96],"(ethanol)":[97],"nonpolar":[99],"(hexane).":[100],"Metabolite":[101],"profiling":[102,108],"was":[103],"performed":[104],"using":[105],"untargeted":[106],"metabolomic":[107],"via":[109,216],"liquid":[110],"chromatography":[111],"coupled":[112],"high-resolution":[114],"tandem":[115],"mass":[116,185],"spectrometry":[117],"method":[118],"analysis,":[119],"then":[121],"antioxidant":[122,214,229],"capabilities":[125,215],"assessed":[127],"by":[128,236,243],"molecular":[129,156],"docking":[130],"in":[132,277],"vitro":[133],"studies":[134],"on":[135],"selected":[136],"receptors.":[137],"Results:":[138],"A":[139],"total":[140],"9":[142],"11":[144],"observed":[147,161],"from":[148],"continued":[155],"docking.":[157],"Some":[158],"compounds":[162,193],"promising":[164,267],"inhibitors":[167],"human":[169,180],"inducible":[170],"nitric":[171],"oxide":[172],"synthase,":[173],"reactive":[174],"oxygen":[175],"species":[176],"(ROS)":[177],"1":[178],"kinase,":[179],"pancreatic":[181],"lipase,":[182],"fat":[184],"obesity-associated":[187],"(FTO)":[188],"proteins,":[189],"including":[190],"luteolin,":[191],"6-hydroxy":[192],"luteolin":[194],"O-glucoside,":[195],"luteolin-O-sulphate,":[196],"Thalassiolin":[197,199],"A,":[198],"C,":[200],"kaempferol-7,4'-dimethylether-3-O-sulfate,":[201],"apigenin,":[202],"diosmetin.":[204],"ethanol":[207],"extract":[208],"(THE)":[209],"EC":[210,237,254],"50":[211,238,251,255],"value":[212,226],"shows":[213],"ABTS":[217],"radical":[218],"scavenging":[219],"activity":[220,242,269],"76.00":[222],"\u03bcg/mL,":[223],"smaller":[225],"than":[227],"standard":[228],"controls":[230],"(Trolox,":[231],"76.54":[232],"\u03bcg/mL)":[233],"followed":[235],"lipase":[240],"inhibition":[241],"THE":[244,252],"has":[246],"same":[248],"pattern":[249],"(EC":[250],"<":[253],"Orlistat).":[256],"Conclusions":[257],"This":[259],"concludes":[260],"seagrasses":[265],"candidates":[271],"functional":[273],"food":[274],"and/or":[275],"drugs":[276],"combating":[278],"free":[279],"radicals":[280],"obesity.":[282]},"counts_by_year":[],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2025-10-10T00:00:00"}