{"id":"https://openalex.org/W4416323754","doi":"https://doi.org/10.2196/83346","title":"Implementation of a Mobile Digital Tool Supporting Medication for Opioid Use Disorder Treatment Improves Retention: Stepped-Wedge Cluster Randomized Controlled Trial","display_name":"Implementation of a Mobile Digital Tool Supporting Medication for Opioid Use Disorder Treatment Improves Retention: Stepped-Wedge Cluster Randomized Controlled Trial","publication_year":2025,"publication_date":"2025-11-18","ids":{"openalex":"https://openalex.org/W4416323754","doi":"https://doi.org/10.2196/83346","pmid":"https://pubmed.ncbi.nlm.nih.gov/41429011","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12770919"},"language":"en","primary_location":{"id":"doi:10.2196/83346","doi":"https://doi.org/10.2196/83346","is_oa":true,"landing_page_url":"https://doi.org/10.2196/83346","pdf_url":null,"source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.2196/83346","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091371124","display_name":"Jorge E. Palacios","orcid":"https://orcid.org/0000-0002-2103-5507","observed_orcids":["https://orcid.org/0000-0002-2103-5507"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jorge E Palacios","raw_affiliation_strings":["Bright Therapeutics, San Francisco, CA, United States"],"raw_orcid":"https://orcid.org/0000-0002-2103-5507","affiliations":[{"raw_affiliation_string":"Bright Therapeutics, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055418194","display_name":"Robert C. Sherrick","orcid":"https://orcid.org/0000-0002-4436-0134","observed_orcids":["https://orcid.org/0000-0002-4436-0134"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert Sherrick","raw_affiliation_strings":["Community Medical Services, Scottsdale, AZ, United States"],"raw_orcid":"https://orcid.org/0000-0002-4436-0134","affiliations":[{"raw_affiliation_string":"Community Medical Services, Scottsdale, AZ, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039001569","display_name":"Tim Janssen","orcid":"https://orcid.org/0000-0003-0012-2609","observed_orcids":["https://orcid.org/0000-0003-0012-2609"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tim Janssen","raw_affiliation_strings":["Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, United States"],"raw_orcid":"https://orcid.org/0000-0003-0012-2609","affiliations":[{"raw_affiliation_string":"Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, United States","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115399049","display_name":"Elana Deuble","orcid":"https://orcid.org/0009-0000-2050-9566","observed_orcids":["https://orcid.org/0009-0000-2050-9566"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elana Deuble","raw_affiliation_strings":["Community Medical Services, Scottsdale, AZ, United States"],"raw_orcid":"https://orcid.org/0009-0000-2050-9566","affiliations":[{"raw_affiliation_string":"Community Medical Services, Scottsdale, AZ, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sara Lorenzen","orcid":"https://orcid.org/0009-0000-4148-2411","observed_orcids":["https://orcid.org/0009-0000-4148-2411"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sara Lorenzen","raw_affiliation_strings":["Bright Therapeutics, San Francisco, CA, United States"],"raw_orcid":"https://orcid.org/0009-0000-4148-2411","affiliations":[{"raw_affiliation_string":"Bright Therapeutics, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mark Schaefer","orcid":"https://orcid.org/0009-0003-8417-8913","observed_orcids":["https://orcid.org/0009-0003-8417-8913"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark Schaefer","raw_affiliation_strings":["Community Medical Services, Scottsdale, AZ, United States"],"raw_orcid":"https://orcid.org/0009-0003-8417-8913","affiliations":[{"raw_affiliation_string":"Community Medical Services, Scottsdale, AZ, United States","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027243024","display_name":"Jenna Tregarthen","orcid":"https://orcid.org/0000-0002-4787-7059","observed_orcids":["https://orcid.org/0000-0002-4787-7059"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jenna Tregarthen","raw_affiliation_strings":["Bright Therapeutics, San Francisco, CA, United States"],"raw_orcid":"https://orcid.org/0000-0002-4787-7059","affiliations":[{"raw_affiliation_string":"Bright Therapeutics, San Francisco, CA, United States","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5091371124"],"corresponding_institution_ids":[],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":0.8137,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.76108198,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":95},"biblio":{"volume":"27","issue":null,"first_page":"e83346","last_page":"e83346"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/opioid-use-disorder","display_name":"opioid use disorder","score":0.9599999785423279},{"id":"https://openalex.org/keywords/medication-assisted-treatment","display_name":"medication-assisted treatment","score":0.9649999737739563},{"id":"https://openalex.org/keywords/mobile-health-apps","display_name":"mobile health apps","score":0.6079999804496765},{"id":"https://openalex.org/keywords/patient-retention","display_name":"patient retention","score":0.6570000052452087},{"id":"https://openalex.org/keywords/treatment-continuity","display_name":"treatment continuity","score":0.5490000247955322},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.7749999761581421},{"id":"https://openalex.org/keywords/remote-patient-monitoring","display_name":"remote patient monitoring","score":0.9210000038146973},{"id":"https://openalex.org/keywords/outpatient-care","display_name":"outpatient care","score":0.3790000081062317},{"id":"https://openalex.org/keywords/digital-interventions","display_name":"digital interventions","score":0.39899998903274536},{"id":"https://openalex.org/keywords/app-engagement","display_name":"app engagement","score":0.6959999799728394},{"id":"https://openalex.org/keywords/linkage-to-care","display_name":"linkage to care","score":0.7519999742507935},{"id":"https://openalex.org/keywords/psychoeducation","display_name":"psychoeducation","score":0.5490000247955322},{"id":"https://openalex.org/keywords/discrete-time-survival-analysis","display_name":"discrete-time survival analysis","score":0.6330000162124634},{"id":"https://openalex.org/keywords/treatment-discontinuation","display_name":"treatment discontinuation","score":0.40400001406669617},{"id":"https://openalex.org/keywords/harm-reduction-clinics","display_name":"harm reduction clinics","score":0.3440000116825104}],"concepts":[{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6575999855995178},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6218000054359436},{"id":"https://openalex.org/C2780433410","wikidata":"https://www.wikidata.org/wiki/Q5276090","display_name":"Digital health","level":3,"score":0.6208999752998352},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.5256999731063843},{"id":"https://openalex.org/C2779418921","wikidata":"https://www.wikidata.org/wiki/Q1639178","display_name":"Opioid use disorder","level":4,"score":0.5138999819755554},{"id":"https://openalex.org/C2779891985","wikidata":"https://www.wikidata.org/wiki/Q46994","display_name":"Telemedicine","level":3,"score":0.4758000075817108},{"id":"https://openalex.org/C2779363104","wikidata":"https://www.wikidata.org/wiki/Q17069079","display_name":"mHealth","level":3,"score":0.41190001368522644},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.4041000008583069},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.39259999990463257},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.37549999356269836},{"id":"https://openalex.org/C3018553135","wikidata":"https://www.wikidata.org/wiki/Q67004728","display_name":"Medication adherence","level":2,"score":0.3352000117301941},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.2727999985218048},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.2687000036239624},{"id":"https://openalex.org/C2781050511","wikidata":"https://www.wikidata.org/wiki/Q46994","display_name":"Telehealth","level":4,"score":0.26570001244544983},{"id":"https://openalex.org/C176400912","wikidata":"https://www.wikidata.org/wiki/Q3058662","display_name":"Cluster randomised controlled trial","level":3,"score":0.25839999318122864},{"id":"https://openalex.org/C2988145974","wikidata":"https://www.wikidata.org/wiki/Q620615","display_name":"Mobile apps","level":2,"score":0.257999986410141},{"id":"https://openalex.org/C110875604","wikidata":"https://www.wikidata.org/wiki/Q75","display_name":"The Internet","level":2,"score":0.25270000100135803},{"id":"https://openalex.org/C202645933","wikidata":"https://www.wikidata.org/wiki/Q4930","display_name":"eHealth","level":3,"score":0.25200000405311584},{"id":"https://openalex.org/C41260284","wikidata":"https://www.wikidata.org/wiki/Q6956315","display_name":"N of 1 trial","level":3,"score":0.25029999017715454}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009293","descriptor_name":"Opioid-Related Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D017216","descriptor_name":"Telemedicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055118","descriptor_name":"Medication Adherence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.2196/83346","doi":"https://doi.org/10.2196/83346","is_oa":true,"landing_page_url":"https://doi.org/10.2196/83346","pdf_url":null,"source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},{"id":"doi:10.2196/preprints.83346","doi":"https://doi.org/10.2196/preprints.83346","is_oa":true,"landing_page_url":"https://doi.org/10.2196/preprints.83346","pdf_url":"https://s3.ca-central-1.amazonaws.com/assets.jmir.org/assets/preprints/preprint-83346-submitted.pdf","source":null,"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"doi:10.31234/osf.io/9jhpf_v1","doi":"https://doi.org/10.31234/osf.io/9jhpf_v1","is_oa":true,"landing_page_url":"https://doi.org/10.31234/osf.io/9jhpf_v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmid:41429011","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41429011","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medical Internet research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12770919","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12770919/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Med Internet Res","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:745f549ac9dd4cd18b0effc3aa285738","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/745f549ac9dd4cd18b0effc3aa285738","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Medical Internet Research, Vol 27, p e83346 (2025)","raw_type":"article"},{"id":"pmh:oai:share.osf.io:e3fb7324-0046-49d5-8ddc-59aab3c5b209","doi":null,"is_oa":true,"landing_page_url":"https://osf.io/9jhpf","pdf_url":null,"source":{"id":"https://openalex.org/S4306401687","display_name":"PsyArXiv (OSF Preprints)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2799848540","host_organization_name":"Center for Open Science","host_organization_lineage":["https://openalex.org/I2799848540"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"}],"best_oa_location":{"id":"doi:10.2196/83346","doi":"https://doi.org/10.2196/83346","is_oa":true,"landing_page_url":"https://doi.org/10.2196/83346","pdf_url":null,"source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4416323754.pdf","grobid_xml":"https://content.openalex.org/works/W4416323754.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1998724987","https://openalex.org/W2025376268","https://openalex.org/W2037608980","https://openalex.org/W2110065044","https://openalex.org/W2315631840","https://openalex.org/W2900863520","https://openalex.org/W2906591149","https://openalex.org/W2917542064","https://openalex.org/W2956150492","https://openalex.org/W3084315235","https://openalex.org/W3095492073","https://openalex.org/W3170140544","https://openalex.org/W3194888218","https://openalex.org/W4226231332","https://openalex.org/W4281251362","https://openalex.org/W4281773489","https://openalex.org/W4384522525","https://openalex.org/W4386611970","https://openalex.org/W4400083681","https://openalex.org/W4408279597","https://openalex.org/W4408290272","https://openalex.org/W4408846107","https://openalex.org/W4409568924"],"related_works":["https://openalex.org/W4411367621","https://openalex.org/W4414765517","https://openalex.org/W7137007808","https://openalex.org/W4220913435","https://openalex.org/W4404905116","https://openalex.org/W4225164540","https://openalex.org/W4406607025","https://openalex.org/W3096038073","https://openalex.org/W4225009862","https://openalex.org/W4407068572"],"abstract_inverted_index":{"BACKGROUND:":[0],"Despite":[1],"its":[2],"proven":[3],"efficacy,":[4],"retention":[5,59,159,238,314,334],"in":[6,57,160,168,244,338,413],"medication":[7,106],"for":[8,54,97,220,395],"opioid":[9,98,340],"use":[10,99,341,415],"disorder":[11,342],"(MOUD)":[12],"remains":[13,64],"low,":[14],"with":[15,62,242,257,272,310,316,376],"structural":[16],"and":[17,24,31,60,82,105,145,148,152,173,208,222,255,286,298,304,335,346,387,400,407],"systemic":[18],"barriers-such":[19],"as":[20,90,189],"access":[21],"to":[22,34,45,70,132,175,228,404],"care":[23,131,386],"treatment":[25,63,95,103,161,187,284,336],"setting-alongside":[26],"individual":[27],"factors,":[28],"including":[29],"personalization":[30],"motivation,":[32],"contributing":[33],"high":[35,305],"rates":[36],"of":[37,48,74,79,92,165,181,194,199,269,290,355,361,371,385,410],"discontinuation.":[38],"Digital":[39],"interventions":[40],"offer":[41],"a":[42,83,93,133,258,287],"promising":[43],"approach":[44],"address":[46],"many":[47],"these":[49],"barriers;":[50],"however,":[51],"robust":[52],"evidence":[53,324,378],"their":[55],"effectiveness":[56,370],"improving":[58],"engagement":[61,179,306,318,347],"scarce.":[65],"OBJECTIVE:":[66],"This":[67,321],"study":[68,322],"aims":[69],"evaluate":[71],"the":[72,166,169,176,197,204,233,295,349,359,369,393],"impact":[73],"Recovery":[75,80,138,263,327],"Connect-a":[76],"white-labeled":[77],"version":[78],"Path":[81],"digital":[84,364,411],"remote":[85,381],"patient":[86,101,333],"monitoring":[87,382],"app":[88,167,182,234],"used":[89],"part":[91],"blended":[94,372],"model":[96,136],"disorder-on":[100],"retention,":[102,270],"continuance,":[104],"adherence.":[107],"METHODS:":[108],"A":[109],"stepped-wedge":[110],"cluster":[111],"randomized":[112],"trial":[113],"was":[114,157],"conducted":[115],"across":[116],"9":[117],"outpatient":[118,339],"MOUD":[119],"clinics,":[120],"organized":[121],"into":[122],"8":[123],"clusters.":[124],"Clusters":[125],"were":[126,217,308,352],"sequentially":[127],"transitioned":[128],"from":[129],"usual":[130],"digitally":[134],"enhanced":[135],"incorporating":[137],"Connect,":[139],"which":[140],"provided":[141],"real-time":[142],"monitoring,":[143],"psychoeducational":[144],"skill-based":[146],"content,":[147],"messaging":[149],"between":[150],"patients":[151],"clinicians.":[153],"The":[154],"primary":[155],"outcome":[156],"30-day":[158,313],"following":[162],"exposure":[163],"(implementation":[164],"clinic),":[170],"linkage":[171,345],"(downloading":[172],"connecting":[174],"app),":[177],"or":[178],"(levels":[180],"usage).":[183],"Secondary":[184],"outcomes":[185],"included":[186],"continuance-defined":[188],"receiving":[190],"at":[191],"least":[192],"75%":[193],"expected":[195],"doses-and":[196],"number":[198,289],"daily":[200,291],"doses":[201,292],"taken":[202,293],"within":[203],"first":[205,296,350],"3,":[206],"7,":[207],"30":[209,299],"days":[210,300],"after":[211],"admission.":[212],"Cluster-controlled":[213],"discrete-time":[214],"survival":[215],"analyses":[216],"conducted,":[218],"adjusting":[219],"patient-":[221],"clinic-level":[223],"covariates.":[224],"RESULTS:":[225],"Patients":[226,252],"admitted":[227],"clinics":[229,245],"that":[230,246,325,379],"had":[231,247,265],"implemented":[232],"(n=1205)":[235],"showed":[236],"increased":[237],"(922/1205,":[239],"75.5%)":[240],"compared":[241,271,315],"those":[243,276],"not":[248,277],"(203/319,":[249],"63.6%,":[250],"P<.001).":[251],"who":[253],"downloaded":[254],"linked":[256],"mental":[259],"health":[260],"professional":[261],"on":[262],"Connect":[264,328],"an":[266],"81.3%":[267],"likelihood":[268],"72.0%":[273],"(P<.001)":[274],"among":[275],"linked.":[278],"Linkage":[279],"also":[280],"significantly":[281,331],"predicted":[282],"higher":[283,312],"continuance":[285],"greater":[288],"during":[294,348],"7":[297],"(P<.001).":[301,319],"Low,":[302],"moderate,":[303],"levels":[307],"associated":[309],"progressively":[311],"no":[317],"CONCLUSIONS:":[320],"provides":[323],"implementing":[326],"(Recovery":[329],"Path)":[330],"enhances":[332,383],"continuity":[337,384],"care.":[343],"Early":[344],"week":[351],"strong":[353],"predictors":[354],"positive":[356],"outcomes,":[357],"underscoring":[358],"value":[360],"early,":[362],"proactive":[363],"support.":[365],"These":[366],"findings":[367],"reinforce":[368],"digital-clinical":[373],"models,":[374],"aligning":[375],"broader":[377],"integrating":[380],"supports":[388],"recovery.":[389],"Policy":[390],"implications":[391],"include":[392],"need":[394],"reimbursement":[396],"mechanisms,":[397],"workflow":[398],"integration,":[399],"ethical,":[401],"privacy-preserving":[402],"implementation":[403],"enable":[405],"scalable":[406],"equitable":[408],"adoption":[409],"tools":[412],"substance":[414],"treatment.":[416],"TRIAL":[417],"REGISTRATION:":[418],"ClinicalTrials.gov":[419],"NCT07140926;":[420],"https://clinicaltrials.gov/ct2/show/NCT07140926.":[421]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2025-11-18T00:00:00"}