{"id":"https://openalex.org/W4416005133","doi":"https://doi.org/10.1530/edm-24-0094","title":"Management of a mixed ACTH- and prolactin-secreting pituitary adenoma during pregnancy","display_name":"Management of a mixed ACTH- and prolactin-secreting pituitary adenoma during pregnancy","publication_year":2025,"publication_date":"2025-10-01","ids":{"openalex":"https://openalex.org/W4416005133","doi":"https://doi.org/10.1530/edm-24-0094","pmid":"https://pubmed.ncbi.nlm.nih.gov/41201503"},"language":"en","primary_location":{"id":"doi:10.1530/edm-24-0094","doi":"https://doi.org/10.1530/edm-24-0094","is_oa":true,"landing_page_url":"https://doi.org/10.1530/edm-24-0094","pdf_url":null,"source":{"id":"https://openalex.org/S2738451715","display_name":"Endocrinology Diabetes and Metabolism Case Reports","issn_l":"2052-0573","issn":["2052-0573"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology, Diabetes & Metabolism Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1530/edm-24-0094","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028183363","display_name":"A. Lerigoleur","orcid":"https://orcid.org/0009-0006-6967-7572","observed_orcids":["https://orcid.org/0009-0006-6967-7572"]},"institutions":[{"id":"https://openalex.org/I1315288073","display_name":"Cliniques Universitaires Saint-Luc","ror":"https://ror.org/03s4khd80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I1315288073"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Astrid Le Rigoleur","raw_affiliation_strings":["1","Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium"],"raw_orcid":"https://orcid.org/0009-0006-6967-7572","affiliations":[{"raw_affiliation_string":"1","institution_ids":[]},{"raw_affiliation_string":"Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium","institution_ids":["https://openalex.org/I1315288073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032726062","display_name":"Stefan Matei Constantinescu","orcid":"https://orcid.org/0000-0003-2665-9455","observed_orcids":["https://orcid.org/0000-0003-2665-9455"]},"institutions":[{"id":"https://openalex.org/I1315288073","display_name":"Cliniques Universitaires Saint-Luc","ror":"https://ror.org/03s4khd80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I1315288073"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Stefan Matei Constantinescu","raw_affiliation_strings":["1","Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium"],"raw_orcid":"https://orcid.org/0000-0003-2665-9455","affiliations":[{"raw_affiliation_string":"1","institution_ids":[]},{"raw_affiliation_string":"Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium","institution_ids":["https://openalex.org/I1315288073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031519754","display_name":"Lina Daoud","orcid":"https://orcid.org/0000-0002-7670-0092","observed_orcids":["https://orcid.org/0000-0002-7670-0092"]},"institutions":[{"id":"https://openalex.org/I1315288073","display_name":"Cliniques Universitaires Saint-Luc","ror":"https://ror.org/03s4khd80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I1315288073"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Lina Daoud","raw_affiliation_strings":["2","Department of Neuropathology, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2","institution_ids":[]},{"raw_affiliation_string":"Department of Neuropathology, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium","institution_ids":["https://openalex.org/I1315288073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077355483","display_name":"Martin M. Y. Lammens","orcid":"https://orcid.org/0000-0002-3881-6692","observed_orcids":["https://orcid.org/0000-0002-3881-6692"]},"institutions":[{"id":"https://openalex.org/I1315288073","display_name":"Cliniques Universitaires Saint-Luc","ror":"https://ror.org/03s4khd80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I1315288073"]},{"id":"https://openalex.org/I149213910","display_name":"University of Antwerp","ror":"https://ror.org/008x57b05","country_code":"BE","type":"education","lineage":["https://openalex.org/I149213910"]},{"id":"https://openalex.org/I4210102047","display_name":"Antwerp University Hospital","ror":"https://ror.org/01hwamj44","country_code":"BE","type":"funder","lineage":["https://openalex.org/I4210102047"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Martin Lammens","raw_affiliation_strings":["2","3","Department of Neuropathology, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium","Department of Pathology, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2","institution_ids":[]},{"raw_affiliation_string":"3","institution_ids":[]},{"raw_affiliation_string":"Department of Neuropathology, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium","institution_ids":["https://openalex.org/I1315288073"]},{"raw_affiliation_string":"Department of Pathology, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium","institution_ids":["https://openalex.org/I149213910","https://openalex.org/I4210102047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044001809","display_name":"Edward Fomekong","orcid":"https://orcid.org/0000-0002-3269-7960","observed_orcids":["https://orcid.org/0000-0002-3269-7960","https://orcid.org/0009-0003-9998-3499"]},"institutions":[{"id":"https://openalex.org/I1315288073","display_name":"Cliniques Universitaires Saint-Luc","ror":"https://ror.org/03s4khd80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I1315288073"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Edward Fomekong","raw_affiliation_strings":["4","Department of Neurosurgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4","institution_ids":[]},{"raw_affiliation_string":"Department of Neurosurgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium","institution_ids":["https://openalex.org/I1315288073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002318624","display_name":"Fr\u00e9d\u00e9ric Debi\u00e8ve","orcid":"https://orcid.org/0000-0002-8033-2245","observed_orcids":["https://orcid.org/0000-0002-8033-2245"]},"institutions":[{"id":"https://openalex.org/I1315288073","display_name":"Cliniques Universitaires Saint-Luc","ror":"https://ror.org/03s4khd80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I1315288073"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Fr\u00e9d\u00e9ric Debi\u00e8ve","raw_affiliation_strings":["5","Department of Obstetrics, Cliniques Universitaires Saint-Luc, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"5","institution_ids":[]},{"raw_affiliation_string":"Department of Obstetrics, Cliniques Universitaires Saint-Luc, Brussels, Belgium","institution_ids":["https://openalex.org/I1315288073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033181736","display_name":"Dominique M. Maiter","orcid":"https://orcid.org/0000-0002-0918-637X","observed_orcids":["https://orcid.org/0000-0002-0918-637X"]},"institutions":[{"id":"https://openalex.org/I1315288073","display_name":"Cliniques Universitaires Saint-Luc","ror":"https://ror.org/03s4khd80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I1315288073"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Dominique Maiter","raw_affiliation_strings":["1","Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1","institution_ids":[]},{"raw_affiliation_string":"Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium","institution_ids":["https://openalex.org/I1315288073"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078203915","display_name":"Orsalia Alexopoulou","orcid":"https://orcid.org/0000-0001-9933-7188","observed_orcids":["https://orcid.org/0000-0001-9933-7188"]},"institutions":[{"id":"https://openalex.org/I1315288073","display_name":"Cliniques Universitaires Saint-Luc","ror":"https://ror.org/03s4khd80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I1315288073"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Orsalia Alexopoulou","raw_affiliation_strings":["1","Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1","institution_ids":[]},{"raw_affiliation_string":"Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium","institution_ids":["https://openalex.org/I1315288073"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":499,"currency":"GBP","value_usd":612},"apc_paid":{"value":499,"currency":"GBP","value_usd":612},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.35749229,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2025","issue":"4","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11054","display_name":"Adrenal and Paraganglionic Tumors","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cushing-disease","display_name":"Cushing's disease","score":0.8420000076293945},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.8820000290870667},{"id":"https://openalex.org/keywords/cabergoline","display_name":"cabergoline","score":0.6639999747276306},{"id":"https://openalex.org/keywords/transsphenoidal-surgery","display_name":"transsphenoidal surgery","score":0.9419999718666077},{"id":"https://openalex.org/keywords/hyperprolactinemia","display_name":"hyperprolactinemia","score":0.8119999766349792},{"id":"https://openalex.org/keywords/gestational-diabetes-mellitus","display_name":"gestational diabetes mellitus","score":0.5},{"id":"https://openalex.org/keywords/dopamine-agonists","display_name":"dopamine agonists","score":0.6019999980926514},{"id":"https://openalex.org/keywords/preconception-counseling","display_name":"preconception counseling","score":0.8830000162124634},{"id":"https://openalex.org/keywords/pituitary-adenoma","display_name":"pituitary adenoma","score":0.4650000035762787},{"id":"https://openalex.org/keywords/galactorrhea","display_name":"galactorrhea","score":0.8299999833106995}],"concepts":[{"id":"https://openalex.org/C2779832395","wikidata":"https://www.wikidata.org/wiki/Q423308","display_name":"Cabergoline","level":4,"score":0.9189000129699707},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9154999852180481},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.8076000213623047},{"id":"https://openalex.org/C2778918492","wikidata":"https://www.wikidata.org/wiki/Q954831","display_name":"Prolactinoma","level":4,"score":0.7196000218391418},{"id":"https://openalex.org/C2778058571","wikidata":"https://www.wikidata.org/wiki/Q334655","display_name":"Amenorrhea","level":3,"score":0.6880999803543091},{"id":"https://openalex.org/C2910141127","wikidata":"https://www.wikidata.org/wiki/Q7199538","display_name":"Pituitary disorder","level":3,"score":0.46709999442100525},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.46140000224113464},{"id":"https://openalex.org/C2779318953","wikidata":"https://www.wikidata.org/wiki/Q864296","display_name":"Pituitary adenoma","level":3,"score":0.4546999931335449},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.43209999799728394},{"id":"https://openalex.org/C2780214960","wikidata":"https://www.wikidata.org/wiki/Q7199538","display_name":"Pituitary disease","level":3,"score":0.41589999198913574},{"id":"https://openalex.org/C2780853582","wikidata":"https://www.wikidata.org/wiki/Q25556","display_name":"Anovulation","level":5,"score":0.4097000062465668},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.3765999972820282},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.37470000982284546},{"id":"https://openalex.org/C2781449511","wikidata":"https://www.wikidata.org/wiki/Q864296","display_name":"Pituitary tumors","level":2,"score":0.3562999963760376},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3555000126361847},{"id":"https://openalex.org/C2779064019","wikidata":"https://www.wikidata.org/wiki/Q66590068","display_name":"Prolactin","level":3,"score":0.3240000009536743},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.322299987077713},{"id":"https://openalex.org/C2777428134","wikidata":"https://www.wikidata.org/wiki/Q272741","display_name":"Adenoma","level":2,"score":0.30889999866485596},{"id":"https://openalex.org/C2777658017","wikidata":"https://www.wikidata.org/wiki/Q156871","display_name":"Pituitary gland","level":3,"score":0.30720001459121704},{"id":"https://openalex.org/C2777433750","wikidata":"https://www.wikidata.org/wiki/Q189580","display_name":"Acromegaly","level":4,"score":0.30480000376701355},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.301800012588501},{"id":"https://openalex.org/C2778717949","wikidata":"https://www.wikidata.org/wiki/Q415752","display_name":"Pergolide","level":5,"score":0.28110000491142273},{"id":"https://openalex.org/C3018745865","wikidata":"https://www.wikidata.org/wiki/Q749115","display_name":"Postpartum period","level":3,"score":0.26980000734329224},{"id":"https://openalex.org/C2908910360","wikidata":"https://www.wikidata.org/wiki/Q7199538","display_name":"Pituitary neoplasm","level":4,"score":0.26840001344680786},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.26339998841285706},{"id":"https://openalex.org/C81182388","wikidata":"https://www.wikidata.org/wiki/Q353963","display_name":"Complication","level":2,"score":0.25279998779296875}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1530/edm-24-0094","doi":"https://doi.org/10.1530/edm-24-0094","is_oa":true,"landing_page_url":"https://doi.org/10.1530/edm-24-0094","pdf_url":null,"source":{"id":"https://openalex.org/S2738451715","display_name":"Endocrinology Diabetes and Metabolism Case Reports","issn_l":"2052-0573","issn":["2052-0573"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology, Diabetes & Metabolism Case Reports","raw_type":"journal-article"},{"id":"pmid:41201503","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41201503","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology, diabetes & metabolism case reports","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:11412217","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12603899","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:203cf98899cb403894d6cc17db4956b9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/203cf98899cb403894d6cc17db4956b9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Endocrinology, Diabetes & Metabolism Case Reports, Vol 2025, Iss 4 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1530/edm-24-0094","doi":"https://doi.org/10.1530/edm-24-0094","is_oa":true,"landing_page_url":"https://doi.org/10.1530/edm-24-0094","pdf_url":null,"source":{"id":"https://openalex.org/S2738451715","display_name":"Endocrinology Diabetes and Metabolism Case Reports","issn_l":"2052-0573","issn":["2052-0573"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology, Diabetes & Metabolism Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Summary:":[0],"The":[1,117],"diagnosis":[2,367],"and":[3,23,28,51,124,151,167,182,193,219,243,251,260,267,280,285,322,357,363,368,386],"management":[4],"of":[5,17,36,66,99,112,130,147,165,201,204,217,303,312,319,335,347],"Cushing's":[6,265,293,336,351],"disease":[7,294],"(CD)":[8],"during":[9,30,139,314,330,338,355,379,392],"pregnancy":[10,133,218,315,339,356],"are":[11,370],"challenging.":[12],"Only":[13],"a":[14,37,71,80,171,223],"few":[15],"cases":[16,279],"mixed":[18],"pituitary":[19,74,253,309],"adenomas":[20,391],"secreting":[21,308],"prolactin":[22],"ACTH":[24,61,286],"have":[25],"been":[26],"reported,":[27],"none":[29],"pregnancy.":[31,393],"We":[32],"report":[33],"the":[34,89,140,145,188,331,344,348,380],"case":[35],"30-year-old":[38],"woman":[39],"who":[40],"presented":[41,125],"with":[42,59,106,134,174,226,360],"galactorrhea,":[43],"weight":[44],"gain,":[45],"hypertension,":[46],"prediabetes,":[47],"dorsal":[48],"fat":[49],"pad,":[50],"abdominal":[52],"striae.":[53],"Initial":[54],"biochemical":[55,64],"investigations":[56],"revealed":[57],"hyperprolactinemia":[58,153],"increased":[60],"but":[62,88],"no":[63,227],"signs":[65],"hypercortisolism.":[67],"Pituitary":[68],"MRI":[69],"showed":[70,152,170],"10":[72],"mm":[73],"adenoma,":[75],"which":[76],"was":[77,86,104,119,186,194,245],"first":[78,141],"considered":[79],"prolactinoma":[81,313],"potentially":[82],"co-secreting":[83],"ACTH.":[84],"Surgery":[85,185],"indicated,":[87],"patient":[90,118,189],"did":[91],"not":[92],"undergo":[93],"treatment":[94,369,388],"immediately":[95],"due":[96,342],"to":[97,122,144,196,222,263,325,343,372],"lack":[98],"health":[100],"insurance.":[101],"Cabergoline":[102,272],"monotherapy":[103],"initiated,":[105],"close":[107,323],"follow-up":[108,123,324],"advised":[109],"until":[110],"regularization":[111],"social":[113],"status":[114],"in":[115,277,291,301],"Belgium.":[116],"then":[120],"lost":[121],"15":[126],"months":[127,236],"later":[128],"because":[129],"an":[131,275,384],"early":[132],"treatment-resistant":[135],"hypertension.":[136],"Biochemical":[137],"evaluation":[138],"trimester":[142,382],"led":[143],"suspicion":[146],"ACTH-dependent":[148],"cortisol":[149],"excess":[150],"despite":[154],"ongoing":[155],"cabergoline":[156],"treatment.":[157],"She":[158],"underwent":[159,211],"transsphenoidal":[160],"surgery":[161,377],"at":[162,214],"16":[163],"weeks":[164,216],"pregnancy,":[166],"pathological":[168],"examination":[169],"single":[172],"adenoma":[173],"two":[175],"different":[176],"cell":[177],"components":[178],"staining":[179],"for":[180,241,389],"PRL/PIT1":[181],"ACTH/TPIT,":[183],"respectively.":[184],"successful,":[187],"developed":[190],"corticotrope":[191],"insufficiency,":[192],"able":[195],"stop":[197],"antihypertensive":[198],"drugs.":[199],"Because":[200],"failed":[202],"induction":[203],"labor":[205],"(for":[206],"gestational":[207],"insulin-requiring":[208],"diabetes),":[209],"she":[210],"cesarean":[212],"section":[213],"39":[215],"gave":[220],"birth":[221],"healthy":[224],"boy":[225],"maternal":[228,362],"or":[229,269],"neonatal":[230],"complications.":[231,365],"Adrenal":[232],"insufficiency":[233],"recovered":[234],"12":[235],"after":[237],"surgery.":[238],"Genetic":[239],"testing":[240],"MEN1":[242],"AIP":[244],"negative.":[246],"Learning":[247],"points:":[248],"Mixed":[249],"ACTH-":[250],"PRL-secreting":[252],"adenomas,":[254],"although":[255],"extremely":[256],"rare,":[257],"do":[258],"occur":[259],"may":[261,281,353],"lead":[262],"both":[264,283],"syndrome":[266,337,352],"galactorrhea/oligo-":[268],"amenorrhea":[270],"syndrome.":[271],"therapy":[273],"is":[274,295,299,340,358,383],"option":[276],"such":[278],"decrease":[282],"PRL":[284],"levels;":[287],"however,":[288],"its":[289],"efficacy":[290],"controlling":[292],"limited.":[296],"Preconception":[297],"counseling":[298],"essential":[300,371],"women":[302],"childbearing":[304],"age":[305],"suffering":[306],"from":[307],"tumors.":[310],"Management":[311],"usually":[316],"includes":[317],"cessation":[318],"dopamine":[320],"agonists":[321],"detect":[326],"tumor":[327],"growth,":[328],"especially":[329],"third":[332],"trimester.":[333],"Diagnosis":[334],"challenging":[341],"physiological":[345],"activation":[346],"hypothalamic-pituitary-adrenal":[349],"axis.":[350],"worsen":[354],"associated":[359],"severe":[361],"fetal":[364],"Early":[366],"improve":[373],"fetomaternal":[374],"outcomes.":[375],"Transsphenoidal":[376],"performed":[378],"second":[381],"effective":[385],"safe":[387],"ACTH-secreting":[390]},"counts_by_year":[],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2025-11-07T00:00:00"}