{"id":"https://openalex.org/W4415992154","doi":"https://doi.org/10.1007/s00011-025-02126-0","title":"Systemic sclerosis, main culprits and involved signaling pathways","display_name":"Systemic sclerosis, main culprits and involved signaling pathways","publication_year":2025,"publication_date":"2025-11-06","ids":{"openalex":"https://openalex.org/W4415992154","doi":"https://doi.org/10.1007/s00011-025-02126-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/41196296"},"language":"en","primary_location":{"id":"doi:10.1007/s00011-025-02126-0","doi":"https://doi.org/10.1007/s00011-025-02126-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00011-025-02126-0","pdf_url":null,"source":{"id":"https://openalex.org/S55943811","display_name":"Inflammation Research","issn_l":"1023-3830","issn":["1023-3830","1420-908X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation Research","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056953085","display_name":"Omid Sadatpour","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4403928205","display_name":"Research Center for Chronic Inflammatory Diseases","ror":"https://ror.org/00gdrb321","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928205","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Omid Sadatpour","raw_affiliation_strings":["Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran","Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]},{"raw_affiliation_string":"Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I4403928205","https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109753565","display_name":"Amin Azizan","orcid":"https://orcid.org/0000-0001-9633-4678","observed_orcids":["https://orcid.org/0000-0001-9633-4678"]},"institutions":[{"id":"https://openalex.org/I4210108448","display_name":"Shariati Hospital","ror":"https://ror.org/01rb4vv49","country_code":"IR","type":"healthcare","lineage":["https://openalex.org/I4210108448"]},{"id":"https://openalex.org/I4403928205","display_name":"Research Center for Chronic Inflammatory Diseases","ror":"https://ror.org/00gdrb321","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928205","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I4403928248","display_name":"Rheumatology Research Center","ror":"https://ror.org/037d7yy80","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928248","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Amin Azizan","raw_affiliation_strings":["Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran","Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Kargar Ave, P.O. BOX: 1411713137, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I4403928205","https://openalex.org/I70640408"]},{"raw_affiliation_string":"Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Kargar Ave, P.O. BOX: 1411713137, Tehran, Iran","institution_ids":["https://openalex.org/I4210108448","https://openalex.org/I4403928248","https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037642943","display_name":"Hoda Kavosi","orcid":"https://orcid.org/0000-0003-4762-6943","observed_orcids":["https://orcid.org/0000-0003-4762-6943"]},"institutions":[{"id":"https://openalex.org/I4210108448","display_name":"Shariati Hospital","ror":"https://ror.org/01rb4vv49","country_code":"IR","type":"healthcare","lineage":["https://openalex.org/I4210108448"]},{"id":"https://openalex.org/I4403928205","display_name":"Research Center for Chronic Inflammatory Diseases","ror":"https://ror.org/00gdrb321","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928205","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I4403928248","display_name":"Rheumatology Research Center","ror":"https://ror.org/037d7yy80","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928248","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Hoda kavosi","raw_affiliation_strings":["Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran","Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Kargar Ave, P.O. BOX: 1411713137, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I4403928205","https://openalex.org/I70640408"]},{"raw_affiliation_string":"Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Kargar Ave, P.O. BOX: 1411713137, Tehran, Iran","institution_ids":["https://openalex.org/I4210108448","https://openalex.org/I4403928248","https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039140744","display_name":"Mohammad Vodjgani","orcid":"https://orcid.org/0000-0003-0624-3700","observed_orcids":["https://orcid.org/0000-0003-0624-3700"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Vodjgani","raw_affiliation_strings":["Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056940060","display_name":"Elham Farhadi","orcid":"https://orcid.org/0000-0002-4324-2697","observed_orcids":["https://orcid.org/0000-0002-4324-2697"]},"institutions":[{"id":"https://openalex.org/I4210108448","display_name":"Shariati Hospital","ror":"https://ror.org/01rb4vv49","country_code":"IR","type":"healthcare","lineage":["https://openalex.org/I4210108448"]},{"id":"https://openalex.org/I4403928205","display_name":"Research Center for Chronic Inflammatory Diseases","ror":"https://ror.org/00gdrb321","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928205","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I4403928248","display_name":"Rheumatology Research Center","ror":"https://ror.org/037d7yy80","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928248","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Elham Farhadi","raw_affiliation_strings":["Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran. farhadie@tums.ac.ir","Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Kargar Ave, P.O. BOX: 1411713137, Tehran, Iran. farhadie@tums.ac.ir"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran. farhadie@tums.ac.ir","institution_ids":["https://openalex.org/I4403928205","https://openalex.org/I70640408"]},{"raw_affiliation_string":"Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Kargar Ave, P.O. BOX: 1411713137, Tehran, Iran. farhadie@tums.ac.ir","institution_ids":["https://openalex.org/I4210108448","https://openalex.org/I4403928248","https://openalex.org/I70640408"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027436901","display_name":"Mahdi Mahmoudi","orcid":"https://orcid.org/0000-0002-8164-8831","observed_orcids":["https://orcid.org/0000-0002-8164-8831"]},"institutions":[{"id":"https://openalex.org/I4403928205","display_name":"Research Center for Chronic Inflammatory Diseases","ror":"https://ror.org/00gdrb321","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928205","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Mahdi Mahmoudi","raw_affiliation_strings":["Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran. mahmoudim@tums.ac.ir"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran. mahmoudim@tums.ac.ir","institution_ids":["https://openalex.org/I4403928205","https://openalex.org/I70640408"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5027436901","https://openalex.org/A5056940060"],"corresponding_institution_ids":["https://openalex.org/I4210108448","https://openalex.org/I4403928205","https://openalex.org/I4403928248","https://openalex.org/I70640408"],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":null,"fwci":0.5834,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.50959393,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"74","issue":"1","first_page":"158","last_page":"158"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13313","display_name":"Dupuytren's Contracture and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systemic-sclerosis","display_name":"systemic sclerosis","score":1.0},{"id":"https://openalex.org/keywords/fibrosis","display_name":"fibrosis","score":0.7480000257492065},{"id":"https://openalex.org/keywords/tgf-beta-signaling","display_name":"TGF-beta signaling","score":0.8610000014305115},{"id":"https://openalex.org/keywords/raynaud-s-phenomenon","display_name":"Raynaud's phenomenon","score":0.9290000200271606},{"id":"https://openalex.org/keywords/vasospasm","display_name":"vasospasm","score":0.7289999723434448},{"id":"https://openalex.org/keywords/macrophage-polarization","display_name":"macrophage polarization","score":0.8080000281333923},{"id":"https://openalex.org/keywords/m1-m2-macrophages","display_name":"M1/M2 macrophages","score":0.8930000066757202},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.7400000095367432},{"id":"https://openalex.org/keywords/vascular-smooth-muscle-cells","display_name":"vascular smooth muscle cells","score":0.9980000257492065},{"id":"https://openalex.org/keywords/fibroblasts","display_name":"fibroblasts","score":0.9900000095367432},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.9769999980926514},{"id":"https://openalex.org/keywords/integrins","display_name":"integrins","score":0.847000002861023},{"id":"https://openalex.org/keywords/ras-signaling","display_name":"Ras signaling","score":0.6620000004768372},{"id":"https://openalex.org/keywords/myofibroblast-differentiation","display_name":"myofibroblast differentiation","score":0.9789999723434448},{"id":"https://openalex.org/keywords/akt-signaling","display_name":"Akt signaling","score":0.7490000128746033},{"id":"https://openalex.org/keywords/mapk-signaling","display_name":"MAPK signaling","score":0.9990000128746033},{"id":"https://openalex.org/keywords/g-protein-coupled-receptor-signaling","display_name":"G protein-coupled receptor signaling","score":0.9800000190734863},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.6869999766349792},{"id":"https://openalex.org/keywords/hypoxia","display_name":"hypoxia","score":0.6549999713897705},{"id":"https://openalex.org/keywords/autoimmune-connective-tissue-disease","display_name":"autoimmune connective tissue disease","score":0.7720000147819519}],"concepts":[{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.6567999720573425},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6270999908447266},{"id":"https://openalex.org/C207865475","wikidata":"https://www.wikidata.org/wiki/Q1467330","display_name":"Myofibroblast","level":3,"score":0.6202999949455261},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.6017000079154968},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5523999929428101},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.552299976348877},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.49459999799728394},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.49239999055862427},{"id":"https://openalex.org/C195687474","wikidata":"https://www.wikidata.org/wiki/Q409715","display_name":"Integrin","level":3,"score":0.4756999909877777},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.4684000015258789},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.4115000069141388},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.40209999680519104},{"id":"https://openalex.org/C2779395532","wikidata":"https://www.wikidata.org/wiki/Q7916469","display_name":"Vascular smooth muscle","level":3,"score":0.4011000096797943},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38999998569488525},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.33809998631477356},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.3346000015735626},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3181000053882599},{"id":"https://openalex.org/C2776992346","wikidata":"https://www.wikidata.org/wiki/Q111140","display_name":"Endothelium","level":2,"score":0.31779998540878296},{"id":"https://openalex.org/C151166631","wikidata":"https://www.wikidata.org/wiki/Q904514","display_name":"Focal adhesion","level":3,"score":0.2874000072479248},{"id":"https://openalex.org/C150555746","wikidata":"https://www.wikidata.org/wiki/Q210973","display_name":"Cell signaling","level":3,"score":0.2849999964237213},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.27459999918937683},{"id":"https://openalex.org/C2775893135","wikidata":"https://www.wikidata.org/wiki/Q6787792","display_name":"Matricellular protein","level":3,"score":0.2736999988555908},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.2705000042915344},{"id":"https://openalex.org/C137738243","wikidata":"https://www.wikidata.org/wiki/Q189092","display_name":"Cell migration","level":3,"score":0.2703000009059906},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.26440000534057617},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.2621999979019165},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.2535000145435333},{"id":"https://openalex.org/C16224149","wikidata":"https://www.wikidata.org/wiki/Q187637","display_name":"Cell adhesion molecule","level":2,"score":0.25200000405311584}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012595","descriptor_name":"Scleroderma, Systemic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D012595","descriptor_name":"Scleroderma, Systemic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012595","descriptor_name":"Scleroderma, Systemic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016212","descriptor_name":"Transforming Growth Factor beta","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00011-025-02126-0","doi":"https://doi.org/10.1007/s00011-025-02126-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00011-025-02126-0","pdf_url":null,"source":{"id":"https://openalex.org/S55943811","display_name":"Inflammation Research","issn_l":"1023-3830","issn":["1023-3830","1420-908X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation Research","raw_type":"journal-article"},{"id":"pmid:41196296","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41196296","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation research : official journal of the European Histamine Research Society ... [et al.]","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":138,"referenced_works":["https://openalex.org/W1517079251","https://openalex.org/W1554671829","https://openalex.org/W1615763555","https://openalex.org/W1663976198","https://openalex.org/W1760215417","https://openalex.org/W1962973527","https://openalex.org/W1968163551","https://openalex.org/W1987354436","https://openalex.org/W1993976160","https://openalex.org/W2001029428","https://openalex.org/W2011330826","https://openalex.org/W2012993485","https://openalex.org/W2016648062","https://openalex.org/W2018185237","https://openalex.org/W2019788712","https://openalex.org/W2020773931","https://openalex.org/W2045752938","https://openalex.org/W2052334769","https://openalex.org/W2054133760","https://openalex.org/W2058645214","https://openalex.org/W2060346337","https://openalex.org/W2068556120","https://openalex.org/W2078733754","https://openalex.org/W2082335687","https://openalex.org/W2087381746","https://openalex.org/W2108811339","https://openalex.org/W2109353818","https://openalex.org/W2117103793","https://openalex.org/W2121137478","https://openalex.org/W2127829790","https://openalex.org/W2145040563","https://openalex.org/W2146945647","https://openalex.org/W2158591068","https://openalex.org/W2160342986","https://openalex.org/W2162843964","https://openalex.org/W2166503846","https://openalex.org/W2172009773","https://openalex.org/W2342479713","https://openalex.org/W2376694621","https://openalex.org/W2419274075","https://openalex.org/W2507731631","https://openalex.org/W2753771625","https://openalex.org/W2768542634","https://openalex.org/W2789951935","https://openalex.org/W2793465679","https://openalex.org/W2797128264","https://openalex.org/W2797846941","https://openalex.org/W2884840527","https://openalex.org/W2893990283","https://openalex.org/W2901229709","https://openalex.org/W2907407196","https://openalex.org/W2909615353","https://openalex.org/W2916644418","https://openalex.org/W2943665612","https://openalex.org/W2946216991","https://openalex.org/W2957504779","https://openalex.org/W2967026559","https://openalex.org/W2998177202","https://openalex.org/W3003289036","https://openalex.org/W3005055481","https://openalex.org/W3007541218","https://openalex.org/W3008900858","https://openalex.org/W3015333345","https://openalex.org/W3020717237","https://openalex.org/W3022069578","https://openalex.org/W3039944231","https://openalex.org/W3087967802","https://openalex.org/W3089907429","https://openalex.org/W3093427802","https://openalex.org/W3110753020","https://openalex.org/W3114492223","https://openalex.org/W3121001695","https://openalex.org/W3130594016","https://openalex.org/W3136061297","https://openalex.org/W3159969612","https://openalex.org/W3160504883","https://openalex.org/W3192380806","https://openalex.org/W3194258688","https://openalex.org/W3196312012","https://openalex.org/W3206018754","https://openalex.org/W3207022084","https://openalex.org/W3210398420","https://openalex.org/W3210822826","https://openalex.org/W3217612452","https://openalex.org/W4200095324","https://openalex.org/W4200225407","https://openalex.org/W4205104064","https://openalex.org/W4205560753","https://openalex.org/W4210241558","https://openalex.org/W4210505880","https://openalex.org/W4211001791","https://openalex.org/W4211149849","https://openalex.org/W4214535082","https://openalex.org/W4214815303","https://openalex.org/W4214937033","https://openalex.org/W4224300609","https://openalex.org/W4280500566","https://openalex.org/W4281668758","https://openalex.org/W4281691521","https://openalex.org/W4281749682","https://openalex.org/W4285092123","https://openalex.org/W4286486104","https://openalex.org/W4286494884","https://openalex.org/W4288721956","https://openalex.org/W4304127942","https://openalex.org/W4307870015","https://openalex.org/W4310080081","https://openalex.org/W4310208931","https://openalex.org/W4311391401","https://openalex.org/W4316363600","https://openalex.org/W4317743333","https://openalex.org/W4321787862","https://openalex.org/W4360942028","https://openalex.org/W4362579017","https://openalex.org/W4365452585","https://openalex.org/W4372047048","https://openalex.org/W4377206081","https://openalex.org/W4378640103","https://openalex.org/W4380686378","https://openalex.org/W4381144541","https://openalex.org/W4385232682","https://openalex.org/W4385334930","https://openalex.org/W4386499069","https://openalex.org/W4386917815","https://openalex.org/W4387710865","https://openalex.org/W4388124828","https://openalex.org/W4388465360","https://openalex.org/W4391278210","https://openalex.org/W4391798212","https://openalex.org/W4391843307","https://openalex.org/W4393375428","https://openalex.org/W4394806161","https://openalex.org/W4398160671","https://openalex.org/W4399431720","https://openalex.org/W4399668885","https://openalex.org/W4399731913","https://openalex.org/W4400352989","https://openalex.org/W4403313438"],"related_works":["https://openalex.org/W2016477532","https://openalex.org/W4395055913","https://openalex.org/W2027405146","https://openalex.org/W2890783655","https://openalex.org/W3209491216","https://openalex.org/W2572822383","https://openalex.org/W2120264475","https://openalex.org/W2113859552","https://openalex.org/W1975509879","https://openalex.org/W2738265025"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2025-11-06T00:00:00"}