{"id":"https://openalex.org/W4415929619","doi":"https://doi.org/10.1016/j.fertnstert.2025.10.030","title":"Rethinking embryology dogma","display_name":"Rethinking embryology dogma","publication_year":2025,"publication_date":"2025-11-05","ids":{"openalex":"https://openalex.org/W4415929619","doi":"https://doi.org/10.1016/j.fertnstert.2025.10.030","pmid":"https://pubmed.ncbi.nlm.nih.gov/41202946"},"language":"en","primary_location":{"id":"doi:10.1016/j.fertnstert.2025.10.030","doi":"https://doi.org/10.1016/j.fertnstert.2025.10.030","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.fertnstert.2025.10.030","pdf_url":null,"source":{"id":"https://openalex.org/S45445671","display_name":"Fertility and Sterility","issn_l":"0015-0282","issn":["0015-0282","1556-5653"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fertility and Sterility","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040907031","display_name":"Catherine Racowsky","orcid":"https://orcid.org/0000-0002-8961-7896","observed_orcids":["https://orcid.org/0000-0002-8961-7896"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Catherine Racowsky","raw_affiliation_strings":["Ostara Scientific Consulting, Montauban, France. Electronic address: catherine.racowsky@gmail.com","Department of Obstetrics, Gynecology and Reproductive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA:. Electronic address: catherine.racowsky@gmail.com"],"raw_orcid":"https://orcid.org/0000-0002-8961-7896","affiliations":[{"raw_affiliation_string":"Ostara Scientific Consulting, Montauban, France. Electronic address: catherine.racowsky@gmail.com","institution_ids":[]},{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA:. Electronic address: catherine.racowsky@gmail.com","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jacques Cohen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jacques Cohen","raw_affiliation_strings":["Conceivable Life Sciences, New York, New York; IVF 2.0, Liverpool, Merseyside, United Kingdom","Professor EmeritaConceivable Life Sciences, 160 Mercer Street, New York, NY 10012; IVF 2.0, 40 Rodney Street, Liverpool, Merseyside, L1 9AA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Conceivable Life Sciences, New York, New York; IVF 2.0, Liverpool, Merseyside, United Kingdom","institution_ids":[]},{"raw_affiliation_string":"Professor EmeritaConceivable Life Sciences, 160 Mercer Street, New York, NY 10012; IVF 2.0, 40 Rodney Street, Liverpool, Merseyside, L1 9AA, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050479075","display_name":"David K. Gardner","orcid":"https://orcid.org/0000-0003-3138-8274","observed_orcids":["https://orcid.org/0000-0003-3138-8274"]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"David K. Gardner","raw_affiliation_strings":["School of BioSciences, University of Melbourne, Parkville, Victoria, Australia; Melbourne IVF, Collingwood, Victoria, Australia","School of BioSciences, University of Melbourne, Parkville, Vic, Australia; Melbourne IVF, Collingwood, Vic, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of BioSciences, University of Melbourne, Parkville, Victoria, Australia; Melbourne IVF, Collingwood, Victoria, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"School of BioSciences, University of Melbourne, Parkville, Vic, Australia; Melbourne IVF, Collingwood, Vic, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081189347","display_name":"Denny Sakkas","orcid":"https://orcid.org/0000-0002-9509-6791","observed_orcids":["https://orcid.org/0000-0002-9509-6791"]},"institutions":[{"id":"https://openalex.org/I4210165102","display_name":"Boston IVF","ror":"https://ror.org/05xckek43","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210165102"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Denny Sakkas","raw_affiliation_strings":["Boston IVF IVIRMA-Global Research Alliance, Waltham, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston IVF IVIRMA-Global Research Alliance, Waltham, Massachusetts","institution_ids":["https://openalex.org/I4210165102"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033588871","display_name":"Laura Francesca Rienzi","orcid":"https://orcid.org/0000-0001-8104-3958","observed_orcids":["https://orcid.org/0000-0001-8104-3958"]},"institutions":[{"id":"https://openalex.org/I190397597","display_name":"University of Urbino","ror":"https://ror.org/04q4kt073","country_code":"IT","type":"education","lineage":["https://openalex.org/I190397597"]},{"id":"https://openalex.org/I4210162344","display_name":"Clinica Valle Giulia","ror":"https://ror.org/05aq4y378","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210162344"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Laura Rienzi","raw_affiliation_strings":["IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Rome, Italy; Department of Biomolecular Sciences, University of Urbino \"Carlo Bo,\" Urbino, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Rome, Italy; Department of Biomolecular Sciences, University of Urbino \"Carlo Bo,\" Urbino, Italy","institution_ids":["https://openalex.org/I190397597","https://openalex.org/I4210162344"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5040907031"],"corresponding_institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"],"apc_list":{"value":4220,"currency":"USD","value_usd":4220},"apc_paid":null,"fwci":0.5491,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.55869018,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"125","issue":"1","first_page":"2","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.5473999977111816,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.5473999977111816,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.42089998722076416,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11732","display_name":"Assisted Reproductive Technology and Twin Pregnancy","score":0.011500000022351742,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/assisted-reproductive-technology","display_name":"assisted reproduction","score":0.6909999847412109},{"id":"https://openalex.org/keywords/in-vitro-fertilization","display_name":"in vitro fertilization","score":0.8579999804496765},{"id":"https://openalex.org/keywords/embryo-culture","display_name":"embryo culture","score":0.5899999737739563},{"id":"https://openalex.org/keywords/embryo-selection","display_name":"embryo selection","score":0.6840000152587891},{"id":"https://openalex.org/keywords/laboratory-automation","display_name":"laboratory automation","score":0.8450000286102295},{"id":"https://openalex.org/keywords/micromanipulation","display_name":"micromanipulation","score":0.7609999775886536},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"artificial intelligence","score":0.6520000100135803},{"id":"https://openalex.org/keywords/reproducibility","display_name":"reproducibility","score":0.8130000233650208},{"id":"https://openalex.org/keywords/process-control","display_name":"process control","score":0.5299999713897705},{"id":"https://openalex.org/keywords/time-lapse-embryo-monitoring","display_name":"time-lapse embryo imaging","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C115901376","wikidata":"https://www.wikidata.org/wiki/Q184199","display_name":"Automation","level":2,"score":0.5412999987602234},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5338000059127808},{"id":"https://openalex.org/C27971861","wikidata":"https://www.wikidata.org/wiki/Q131683","display_name":"Embryology","level":2,"score":0.5202000141143799},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.45019999146461487},{"id":"https://openalex.org/C2994278967","wikidata":"https://www.wikidata.org/wiki/Q7314318","display_name":"Reproductive technology","level":4,"score":0.44859999418258667},{"id":"https://openalex.org/C2779903281","wikidata":"https://www.wikidata.org/wiki/Q6888026","display_name":"Modalities","level":2,"score":0.44190001487731934},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.4108000099658966},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.3919999897480011},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.35910001397132874},{"id":"https://openalex.org/C176553487","wikidata":"https://www.wikidata.org/wiki/Q7855819","display_name":"Turnaround time","level":2,"score":0.33730000257492065},{"id":"https://openalex.org/C55587333","wikidata":"https://www.wikidata.org/wiki/Q1133029","display_name":"Engineering ethics","level":1,"score":0.3361999988555908},{"id":"https://openalex.org/C207267971","wikidata":"https://www.wikidata.org/wiki/Q120208","display_name":"Emerging technologies","level":2,"score":0.33149999380111694},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3230000138282776},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.31610000133514404},{"id":"https://openalex.org/C58328972","wikidata":"https://www.wikidata.org/wiki/Q184609","display_name":"Expert system","level":2,"score":0.30730000138282776},{"id":"https://openalex.org/C2993153387","wikidata":"https://www.wikidata.org/wiki/Q285223","display_name":"Genetic diagnosis","level":3,"score":0.30300000309944153},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30149999260902405},{"id":"https://openalex.org/C59659247","wikidata":"https://www.wikidata.org/wiki/Q11990","display_name":"Reproduction","level":2,"score":0.29910001158714294},{"id":"https://openalex.org/C512716672","wikidata":"https://www.wikidata.org/wiki/Q200117","display_name":"In vitro fertilisation","level":3,"score":0.29910001158714294},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.2987000048160553},{"id":"https://openalex.org/C135964268","wikidata":"https://www.wikidata.org/wiki/Q3427336","display_name":"Human reproduction","level":2,"score":0.28029999136924744},{"id":"https://openalex.org/C2776291640","wikidata":"https://www.wikidata.org/wiki/Q2912517","display_name":"Value (mathematics)","level":2,"score":0.27900001406669617},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.27649998664855957},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.27079999446868896},{"id":"https://openalex.org/C43214815","wikidata":"https://www.wikidata.org/wiki/Q7310987","display_name":"Reliability (semiconductor)","level":3,"score":0.2669999897480011},{"id":"https://openalex.org/C2780673598","wikidata":"https://www.wikidata.org/wiki/Q285223","display_name":"Genetic testing","level":2,"score":0.26100000739097595},{"id":"https://openalex.org/C2781162219","wikidata":"https://www.wikidata.org/wiki/Q26250693","display_name":"Replicate","level":2,"score":0.258899986743927},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.25679999589920044},{"id":"https://openalex.org/C2780226545","wikidata":"https://www.wikidata.org/wiki/Q6888030","display_name":"Modality (human\u2013computer interaction)","level":2,"score":0.25589999556541443},{"id":"https://openalex.org/C2993458768","wikidata":"https://www.wikidata.org/wiki/Q3477549","display_name":"Special section","level":2,"score":0.2558000087738037}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004626","descriptor_name":"Embryology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004626","descriptor_name":"Embryology","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D004626","descriptor_name":"Embryology","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005307","descriptor_name":"Fertilization in Vitro","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D027724","descriptor_name":"Reproductive Techniques, Assisted","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D046149","descriptor_name":"Embryo Culture Techniques","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.fertnstert.2025.10.030","doi":"https://doi.org/10.1016/j.fertnstert.2025.10.030","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.fertnstert.2025.10.030","pdf_url":null,"source":{"id":"https://openalex.org/S45445671","display_name":"Fertility and Sterility","issn_l":"0015-0282","issn":["0015-0282","1556-5653"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fertility and Sterility","raw_type":"journal-article"},{"id":"pmid:41202946","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41202946","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fertility and sterility","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W1977993923","https://openalex.org/W1978583190","https://openalex.org/W1978590716","https://openalex.org/W1989455265","https://openalex.org/W1994609982","https://openalex.org/W2032297601","https://openalex.org/W2033911590","https://openalex.org/W2069463805","https://openalex.org/W2080018890","https://openalex.org/W2086624692","https://openalex.org/W2086970734","https://openalex.org/W2090718593","https://openalex.org/W2091904117","https://openalex.org/W2103469980","https://openalex.org/W2123860397","https://openalex.org/W2128178522","https://openalex.org/W2131531401","https://openalex.org/W2139241449","https://openalex.org/W2149020863","https://openalex.org/W2157443948","https://openalex.org/W2160428364","https://openalex.org/W2160870513","https://openalex.org/W2182830251","https://openalex.org/W2288983040","https://openalex.org/W2298236605","https://openalex.org/W2524720610","https://openalex.org/W2574385986","https://openalex.org/W2920847689","https://openalex.org/W2927960701","https://openalex.org/W2949941775","https://openalex.org/W3015106848","https://openalex.org/W3132626214","https://openalex.org/W3164947299","https://openalex.org/W3201158319","https://openalex.org/W3208267925","https://openalex.org/W4200543910","https://openalex.org/W4223642954","https://openalex.org/W4308718750","https://openalex.org/W4311671368","https://openalex.org/W4315646576","https://openalex.org/W4376636088","https://openalex.org/W4378190661","https://openalex.org/W4385380242","https://openalex.org/W4385845014","https://openalex.org/W4387893901","https://openalex.org/W4390979791","https://openalex.org/W4394807164","https://openalex.org/W4394857110","https://openalex.org/W4401461817","https://openalex.org/W4401931228","https://openalex.org/W4402567256","https://openalex.org/W4404214517","https://openalex.org/W4404789323","https://openalex.org/W4405471566","https://openalex.org/W4409287487","https://openalex.org/W4409732810","https://openalex.org/W4409732887","https://openalex.org/W4409776923","https://openalex.org/W4409905485","https://openalex.org/W4412938437"],"related_works":["https://openalex.org/W7163383817","https://openalex.org/W3194926497","https://openalex.org/W7160415447","https://openalex.org/W3214095588","https://openalex.org/W7204277587","https://openalex.org/W4409732831","https://openalex.org/W7165359543","https://openalex.org/W4391357888","https://openalex.org/W4311671368","https://openalex.org/W3207904914"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-11-05T00:00:00"}