{"id":"https://openalex.org/W4415733738","doi":"https://doi.org/10.4103/pajo.pajo_94_25","title":"Periocular keratoacanthoma: A clinicopathologic study and diagnostic challenges","display_name":"Periocular keratoacanthoma: A clinicopathologic study and diagnostic challenges","publication_year":2025,"publication_date":"2025-10-01","ids":{"openalex":"https://openalex.org/W4415733738","doi":"https://doi.org/10.4103/pajo.pajo_94_25"},"language":"en","primary_location":{"id":"doi:10.4103/pajo.pajo_94_25","doi":"https://doi.org/10.4103/pajo.pajo_94_25","is_oa":true,"landing_page_url":"https://doi.org/10.4103/pajo.pajo_94_25","pdf_url":null,"source":{"id":"https://openalex.org/S4210203676","display_name":"The Pan-American Journal of Ophthalmology","issn_l":"2666-4909","issn":["2666-4909"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Pan-American Journal of Ophthalmology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4103/pajo.pajo_94_25","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5120203345","display_name":"Eduardo Ballalai Bordon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801766832","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Eduardo Ballalai Bordon","raw_affiliation_strings":["Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada","institution_ids":["https://openalex.org/I2801766832","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031376583","display_name":"Emily Marcotte","orcid":"https://orcid.org/0009-0002-8648-7093","observed_orcids":["https://orcid.org/0009-0002-8648-7093"]},"institutions":[{"id":"https://openalex.org/I2801766832","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Emily Marcotte","raw_affiliation_strings":["Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada","institution_ids":["https://openalex.org/I2801766832","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044038312","display_name":"Jacqueline Coblentz","orcid":"https://orcid.org/0000-0003-1018-7473","observed_orcids":["https://orcid.org/0000-0003-1018-7473"]},"institutions":[{"id":"https://openalex.org/I2801766832","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jacqueline Coblentz","raw_affiliation_strings":["Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada","institution_ids":["https://openalex.org/I2801766832","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085674540","display_name":"Guilherme Feltrin de Barros","orcid":"https://orcid.org/0000-0002-0837-6411","observed_orcids":["https://orcid.org/0000-0002-0837-6411"]},"institutions":[{"id":"https://openalex.org/I2801766832","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Guilherme Feltrin Barros","raw_affiliation_strings":["Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada","institution_ids":["https://openalex.org/I2801766832","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028019532","display_name":"Christian El\u2010Hadad","orcid":"https://orcid.org/0000-0003-3601-0123","observed_orcids":["https://orcid.org/0000-0003-3601-0123"]},"institutions":[{"id":"https://openalex.org/I2801766832","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Christian El-Hadad","raw_affiliation_strings":["Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada","institution_ids":["https://openalex.org/I2801766832","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111849862","display_name":"Massimo Mazza","orcid":"https://orcid.org/0009-0005-3078-9991","observed_orcids":["https://orcid.org/0009-0005-3078-9991"]},"institutions":[{"id":"https://openalex.org/I2801766832","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Massimo Mazza","raw_affiliation_strings":["Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada","institution_ids":["https://openalex.org/I2801766832","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119490949","display_name":"Morgan Yurchuk","orcid":"https://orcid.org/0009-0007-4802-0448","observed_orcids":["https://orcid.org/0009-0007-4802-0448"]},"institutions":[{"id":"https://openalex.org/I2801766832","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Morgan Yurchuk","raw_affiliation_strings":["Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada","institution_ids":["https://openalex.org/I2801766832","https://openalex.org/I5023651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103996050","display_name":"Miguel Noel Burnier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801766832","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Miguel Noel Burnier","raw_affiliation_strings":["Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, MUHC-McGill University Ocular Pathology and Translational Research Laboratory, Montreal, Canada","institution_ids":["https://openalex.org/I2801766832","https://openalex.org/I5023651"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5120203345"],"corresponding_institution_ids":["https://openalex.org/I2801766832","https://openalex.org/I5023651"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.38149964,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11868","display_name":"Cancer and Skin Lesions","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eyelid-tumors","display_name":"eyelid tumors","score":0.8360000252723694},{"id":"https://openalex.org/keywords/histopathology","display_name":"histopathology","score":0.6480000019073486},{"id":"https://openalex.org/keywords/actinic-damage","display_name":"actinic damage","score":0.6700000166893005},{"id":"https://openalex.org/keywords/carcinoma-in-situ","display_name":"carcinoma in situ","score":0.8809999823570251},{"id":"https://openalex.org/keywords/atypia","display_name":"atypia","score":0.6610000133514404},{"id":"https://openalex.org/keywords/squamous-cell-carcinoma-differential-diagnosis","display_name":"squamous cell carcinoma differential diagnosis","score":0.8550000190734863},{"id":"https://openalex.org/keywords/malignant-transformation","display_name":"malignant transformation","score":0.6539999842643738},{"id":"https://openalex.org/keywords/uv-exposure","display_name":"UV exposure","score":0.5889999866485596}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7531999945640564},{"id":"https://openalex.org/C2781302119","wikidata":"https://www.wikidata.org/wiki/Q48228","display_name":"Eyelid","level":2,"score":0.7283999919891357},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.6290000081062317},{"id":"https://openalex.org/C2779022956","wikidata":"https://www.wikidata.org/wiki/Q43748","display_name":"Eyebrow","level":2,"score":0.621999979019165},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5687000155448914},{"id":"https://openalex.org/C60172819","wikidata":"https://www.wikidata.org/wiki/Q4452387","display_name":"Canthus","level":3,"score":0.5378999710083008},{"id":"https://openalex.org/C2778478263","wikidata":"https://www.wikidata.org/wiki/Q212743","display_name":"Acanthosis","level":3,"score":0.5123999714851379},{"id":"https://openalex.org/C2777624698","wikidata":"https://www.wikidata.org/wiki/Q505531","display_name":"Dermis","level":2,"score":0.4952999949455261},{"id":"https://openalex.org/C2781283455","wikidata":"https://www.wikidata.org/wiki/Q1960558","display_name":"Atypia","level":2,"score":0.4668000042438507},{"id":"https://openalex.org/C2777873816","wikidata":"https://www.wikidata.org/wiki/Q422225","display_name":"Actinic keratosis","level":3,"score":0.46380001306533813},{"id":"https://openalex.org/C544855455","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathology","level":2,"score":0.4016000032424927},{"id":"https://openalex.org/C2777845685","wikidata":"https://www.wikidata.org/wiki/Q2166371","display_name":"Seborrheic keratosis","level":2,"score":0.3846000134944916},{"id":"https://openalex.org/C2779286123","wikidata":"https://www.wikidata.org/wiki/Q662298","display_name":"Ectropion","level":3,"score":0.38109999895095825},{"id":"https://openalex.org/C2779915019","wikidata":"https://www.wikidata.org/wiki/Q1640998","display_name":"Hyperkeratosis","level":2,"score":0.3610999882221222},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.3569999933242798},{"id":"https://openalex.org/C3020547009","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathological examination","level":2,"score":0.35679998993873596},{"id":"https://openalex.org/C3019992690","wikidata":"https://www.wikidata.org/wiki/Q92767510","display_name":"Basal cell","level":2,"score":0.35350000858306885},{"id":"https://openalex.org/C2777789703","wikidata":"https://www.wikidata.org/wiki/Q192102","display_name":"Skin cancer","level":3,"score":0.34850001335144043},{"id":"https://openalex.org/C2781019283","wikidata":"https://www.wikidata.org/wiki/Q1852755","display_name":"Trichiasis","level":3,"score":0.3391000032424927},{"id":"https://openalex.org/C2776032170","wikidata":"https://www.wikidata.org/wiki/Q3502247","display_name":"Dermatopathology","level":2,"score":0.3379000127315521},{"id":"https://openalex.org/C2778648961","wikidata":"https://www.wikidata.org/wiki/Q3667186","display_name":"Keratosis","level":2,"score":0.33399999141693115},{"id":"https://openalex.org/C2780860837","wikidata":"https://www.wikidata.org/wiki/Q3801491","display_name":"Epidermolytic hyperkeratosis","level":3,"score":0.3336000144481659},{"id":"https://openalex.org/C2776350330","wikidata":"https://www.wikidata.org/wiki/Q7124339","display_name":"Pagetoid","level":3,"score":0.30640000104904175},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.30300000309944153},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.30169999599456787},{"id":"https://openalex.org/C2994460389","wikidata":"https://www.wikidata.org/wiki/Q681817","display_name":"Epidermoid carcinoma","level":3,"score":0.28790000081062317},{"id":"https://openalex.org/C2777550702","wikidata":"https://www.wikidata.org/wiki/Q838145","display_name":"Leukoplakia","level":3,"score":0.28760001063346863},{"id":"https://openalex.org/C2777779247","wikidata":"https://www.wikidata.org/wiki/Q2420648","display_name":"Eye neoplasm","level":2,"score":0.28690001368522644},{"id":"https://openalex.org/C2909060831","wikidata":"https://www.wikidata.org/wiki/Q1704531","display_name":"Pilomatrixoma","level":2,"score":0.28139999508857727},{"id":"https://openalex.org/C2779049991","wikidata":"https://www.wikidata.org/wiki/Q785827","display_name":"Keratoacanthoma","level":3,"score":0.27219998836517334},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2572000026702881},{"id":"https://openalex.org/C159738032","wikidata":"https://www.wikidata.org/wiki/Q7098087","display_name":"Ophthalmic pathology","level":4,"score":0.2567000091075897},{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.2567000091075897},{"id":"https://openalex.org/C2777661416","wikidata":"https://www.wikidata.org/wiki/Q1035645","display_name":"Carcinoma in situ","level":3,"score":0.2526000142097473}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.4103/pajo.pajo_94_25","doi":"https://doi.org/10.4103/pajo.pajo_94_25","is_oa":true,"landing_page_url":"https://doi.org/10.4103/pajo.pajo_94_25","pdf_url":null,"source":{"id":"https://openalex.org/S4210203676","display_name":"The Pan-American Journal of Ophthalmology","issn_l":"2666-4909","issn":["2666-4909"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Pan-American Journal of Ophthalmology","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:576d34f851c84701b5919a1609c55bee","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/576d34f851c84701b5919a1609c55bee","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Pan-American Journal of Ophthalmology, Vol 7, Iss 1, Pp 191-191 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.4103/pajo.pajo_94_25","doi":"https://doi.org/10.4103/pajo.pajo_94_25","is_oa":true,"landing_page_url":"https://doi.org/10.4103/pajo.pajo_94_25","pdf_url":null,"source":{"id":"https://openalex.org/S4210203676","display_name":"The Pan-American Journal of Ophthalmology","issn_l":"2666-4909","issn":["2666-4909"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Pan-American Journal of Ophthalmology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1137579","https://openalex.org/W1969664524","https://openalex.org/W1977267517","https://openalex.org/W1983078541","https://openalex.org/W2002075820","https://openalex.org/W2042477551","https://openalex.org/W2064758864","https://openalex.org/W2180876464","https://openalex.org/W2597046167","https://openalex.org/W2962282978","https://openalex.org/W3046092828","https://openalex.org/W3154263860","https://openalex.org/W4310113789"],"related_works":["https://openalex.org/W4415177547","https://openalex.org/W3046092828","https://openalex.org/W2082017926","https://openalex.org/W2021688035","https://openalex.org/W4206151896","https://openalex.org/W6981084045","https://openalex.org/W7172258182","https://openalex.org/W3204603207","https://openalex.org/W7128023963","https://openalex.org/W4283826269"],"abstract_inverted_index":{"Abstract":[0],"Purpose:":[1],"Keratoacanthoma":[2],"(KA)":[3],"is":[4,224],"a":[5,11,61,161,239,258],"cutaneous":[6],"neoplasm":[7],"that":[8],"presents":[9],"as":[10,21],"rapidly":[12],"growing":[13],"tumor":[14],"on":[15,99],"ultraviolet":[16],"light-exposed":[17],"skin.":[18],"It":[19],"appears":[20],"an":[22],"exophytic,":[23],"crater-like":[24],"lesion":[25,253],"filled":[26],"with":[27,164,193],"keratin.":[28],"In":[29],"periocular":[30],"sites,":[31],"the":[32,54,80,113,218,225],"eyelids":[33],"are":[34],"most":[35],"often":[36],"affected.":[37],"Clinically,":[38],"diagnosis":[39,261],"and":[40,57,70,75,85,95,104,150,167,169,204,236,252,265],"distinction":[41],"from":[42,79],"squamous":[43],"cell":[44],"carcinoma":[45,175],"can":[46],"be":[47],"difficult.":[48],"This":[49],"study":[50],"aims":[51],"to":[52,66,92,174,249,257],"describe":[53],"histopathological":[55,71,94,105],"features":[56,106],"epidemiological":[58,96],"characteristics":[59],"of":[60,64,220,228,233,241],"large":[62],"series":[63],"KA":[65],"highlight":[67],"its":[68],"clinical":[69,102,260,263],"features.":[72],"Patients,":[73],"Materials,":[74],"Methods:":[76],"Forty-nine":[77],"cases":[78,159,192,211,242],"MUHC-McGill":[81],"University":[82],"Ocular":[83],"Pathology":[84],"Translational":[86],"Research":[87],"Laboratory":[88],"(1997\u20132022)":[89],"were":[90,107,120,123,189],"reviewed":[91],"determine":[93],"traits.":[97],"Data":[98],"age,":[100],"sex,":[101],"site,":[103],"extracted.":[108],"Results:":[109],"Among":[110],"49":[111],"cases,":[112],"average":[114],"age":[115,251],"was":[116,179,200],"65":[117],"years;":[118],"60%":[119],"male.":[121],"Sites":[122],"upper":[124],"eyelid":[125,132,229],"39%":[126,133,182],"(":[127,134,140,146,153,183],"n":[128,135,141,147,154,184],"=":[129,136,142,148,155,185],"19),":[130,137],"lower":[131],"canthus":[138],"8%":[139],"4),":[143],"eyebrow":[144],"2%":[145],"1),":[149],"unspecified":[151],"12%":[152],"6).":[156],"Histopathologically,":[157],"all":[158,208],"displayed":[160],"keratin-filled":[162],"crater":[163],"epidermal":[165],"acanthosis":[166],"hyperkeratosis":[168],"parakeratosis.":[170],"Mild-to-severe":[171],"atypia,":[172],"up":[173],"in":[176,181,191,202,207,238,262],"situ":[177],"(CIS),":[178],"found":[180],"19).":[186],"Mitotic":[187],"figures":[188],"present":[190],"atypia.":[194],"Extensive":[195],"or":[196],"focal":[197],"actinic":[198],"damage":[199],"identified":[201],"superficial":[203],"deep":[205],"dermis":[206],"cases.":[209],"Most":[210],"showed":[212],"chronic,":[213],"nongranulomatous":[214],"inflammation.":[215],"Conclusions:":[216],"To":[217],"best":[219],"our":[221],"knowledge,":[222],"this":[223],"largest":[226],"cohort":[227],"KA.":[230],"The":[231],"presence":[232],"mild-to-severe":[234],"atypia":[235],"CIS":[237],"minority":[240],"did":[243],"not":[244],"indicate":[245],"malignant":[246],"transformation.":[247],"Attention":[248],"patient":[250],"location":[254],"may":[255],"contribute":[256],"correct":[259],"practice":[264],"improve":[266],"diagnostic":[267],"confidence.":[268]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2025-10-31T00:00:00"}