{"id":"https://openalex.org/W4415689262","doi":"https://doi.org/10.1007/s00259-025-07578-4","title":"Effective treatment of human prostate carcinoma xenografts with Single-Dose PSMA-targeted [211At]YF2","display_name":"Effective treatment of human prostate carcinoma xenografts with Single-Dose PSMA-targeted [211At]YF2","publication_year":2025,"publication_date":"2025-10-30","ids":{"openalex":"https://openalex.org/W4415689262","doi":"https://doi.org/10.1007/s00259-025-07578-4","pmid":"https://pubmed.ncbi.nlm.nih.gov/41165817"},"language":"en","primary_location":{"id":"doi:10.1007/s00259-025-07578-4","doi":"https://doi.org/10.1007/s00259-025-07578-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00259-025-07578-4","pdf_url":null,"source":{"id":"https://openalex.org/S191349260","display_name":"European Journal of Nuclear Medicine and Molecular Imaging","issn_l":"1619-7070","issn":["1619-7070","1619-7089"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Nuclear Medicine and Molecular Imaging","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012463373","display_name":"Yutian Feng","orcid":"https://orcid.org/0000-0002-2222-1619","observed_orcids":["https://orcid.org/0000-0002-2222-1619"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yutian Feng","raw_affiliation_strings":["Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057709452","display_name":"Truc T. Huynh","orcid":"https://orcid.org/0000-0001-6423-6715","observed_orcids":["https://orcid.org/0000-0001-6423-6715"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Truc T. Huynh","raw_affiliation_strings":["Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101816276","display_name":"Yongxiang Zheng","orcid":"https://orcid.org/0000-0002-9068-5765","observed_orcids":["https://orcid.org/0000-0002-9068-5765"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yongxiang Zheng","raw_affiliation_strings":["Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rebecca L. Banks","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rebecca L. Banks","raw_affiliation_strings":["Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049568817","display_name":"Martin G. Pomper","orcid":"https://orcid.org/0000-0001-6753-3010","observed_orcids":["https://orcid.org/0000-0001-6753-3010"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin G. Pomper","raw_affiliation_strings":["Department of Radiology, UT Southwestern Medical Center, Dallas, TX, 75390, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, UT Southwestern Medical Center, Dallas, TX, 75390, USA","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003562375","display_name":"Ganesan Vaidyanathan","orcid":"https://orcid.org/0000-0003-3041-8275","observed_orcids":["https://orcid.org/0000-0003-3041-8275"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ganesan Vaidyanathan","raw_affiliation_strings":["Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045964365","display_name":"Michael R. Zalutsky","orcid":"https://orcid.org/0000-0002-5456-0324","observed_orcids":["https://orcid.org/0000-0002-5456-0324"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael R. Zalutsky","raw_affiliation_strings":["Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA. zalut001@mc.duke.edu","Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA"],"raw_orcid":"https://orcid.org/0000-0002-5456-0324","affiliations":[{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA. zalut001@mc.duke.edu","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5045964365"],"corresponding_institution_ids":["https://openalex.org/I4210126298"],"apc_list":{"value":3490,"currency":"USD","value_usd":3490},"apc_paid":null,"fwci":1.555,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.82660272,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"53","issue":"4","first_page":"2304","last_page":"2313"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-specific-membrane-antigen","display_name":"prostate-specific membrane antigen","score":0.8640000224113464},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.7160000205039978},{"id":"https://openalex.org/keywords/alpha-emitting-radionuclide-therapy","display_name":"alpha-emitting radionuclide therapy","score":0.6639999747276306},{"id":"https://openalex.org/keywords/pc-3-xenografts","display_name":"PC-3 xenografts","score":0.8299999833106995},{"id":"https://openalex.org/keywords/tumor-growth-inhibition","display_name":"tumor growth inhibition","score":0.6700000166893005},{"id":"https://openalex.org/keywords/maximum-tolerated-dose","display_name":"maximum tolerated dose","score":0.7900000214576721},{"id":"https://openalex.org/keywords/radiation-toxicity","display_name":"radiation toxicity","score":0.6610000133514404},{"id":"https://openalex.org/keywords/single-dose-treatment","display_name":"single-dose therapy","score":0.5669999718666077},{"id":"https://openalex.org/keywords/survival-benefit","display_name":"survival benefit","score":0.6629999876022339}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8873999714851379},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5720999836921692},{"id":"https://openalex.org/C2993388676","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate carcinoma","level":4,"score":0.5569999814033508},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5512999892234802},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.49639999866485596},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.3952000141143799},{"id":"https://openalex.org/C2776146153","wikidata":"https://www.wikidata.org/wiki/Q7281276","display_name":"Radioimmunotherapy","level":4,"score":0.3465000092983246},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.337799996137619},{"id":"https://openalex.org/C3019894029","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Overall survival","level":2,"score":0.33009999990463257},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3086000084877014},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.2732999920845032},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.2615000009536743}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000954","descriptor_name":"Antigens, Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001246","descriptor_name":"Astatine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D023041","descriptor_name":"Xenograft Model Antitumor Assays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D043425","descriptor_name":"Glutamate Carboxypeptidase II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00259-025-07578-4","doi":"https://doi.org/10.1007/s00259-025-07578-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00259-025-07578-4","pdf_url":null,"source":{"id":"https://openalex.org/S191349260","display_name":"European Journal of Nuclear Medicine and Molecular Imaging","issn_l":"1619-7070","issn":["1619-7070","1619-7089"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Nuclear Medicine and Molecular Imaging","raw_type":"journal-article"},{"id":"pmid:41165817","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41165817","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of nuclear medicine and molecular imaging","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1546887824","display_name":null,"funder_award_id":"CA184228","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2038267290","display_name":"Small Molecule PSMA-Targeted Alpha Therapy","funder_award_id":"R01CA184228","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W1979672521","https://openalex.org/W1980361506","https://openalex.org/W2018649196","https://openalex.org/W2137049679","https://openalex.org/W2343936933","https://openalex.org/W2403516958","https://openalex.org/W2467018059","https://openalex.org/W2740331171","https://openalex.org/W2799908504","https://openalex.org/W2906948885","https://openalex.org/W2954206886","https://openalex.org/W2968654070","https://openalex.org/W2996077865","https://openalex.org/W3094362710","https://openalex.org/W3108377814","https://openalex.org/W3122630556","https://openalex.org/W3125449118","https://openalex.org/W3158974138","https://openalex.org/W3164981285","https://openalex.org/W3172594112","https://openalex.org/W3176267373","https://openalex.org/W3209466759","https://openalex.org/W4225533139","https://openalex.org/W4236153054","https://openalex.org/W4280539505","https://openalex.org/W4281623492","https://openalex.org/W4282927376","https://openalex.org/W4308551039","https://openalex.org/W4313488542","https://openalex.org/W4322757186","https://openalex.org/W4387772562","https://openalex.org/W4392282359","https://openalex.org/W4396540136","https://openalex.org/W4398327992","https://openalex.org/W4399740674","https://openalex.org/W4405465921","https://openalex.org/W4407825915","https://openalex.org/W4408404213","https://openalex.org/W4410278331"],"related_works":["https://openalex.org/W7128542806","https://openalex.org/W4410278331","https://openalex.org/W2602346644","https://openalex.org/W4396540136","https://openalex.org/W4308551039","https://openalex.org/W2585450625","https://openalex.org/W2403516958","https://openalex.org/W4398327992","https://openalex.org/W3164981285","https://openalex.org/W3122630556"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2025-10-30T00:00:00"}