{"id":"https://openalex.org/W4415489698","doi":"https://doi.org/10.3390/nu17213333","title":"Combating Sarcopenia Through Nutrition: Anti-Inflammatory and Antioxidant Properties of Aronia melanocarpa","display_name":"Combating Sarcopenia Through Nutrition: Anti-Inflammatory and Antioxidant Properties of Aronia melanocarpa","publication_year":2025,"publication_date":"2025-10-23","ids":{"openalex":"https://openalex.org/W4415489698","doi":"https://doi.org/10.3390/nu17213333","pmid":"https://pubmed.ncbi.nlm.nih.gov/41228405"},"language":"en","primary_location":{"id":"doi:10.3390/nu17213333","doi":"https://doi.org/10.3390/nu17213333","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu17213333","pdf_url":"https://www.mdpi.com/2072-6643/17/21/3333/pdf?version=1761223940","source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2072-6643/17/21/3333/pdf?version=1761223940","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5098657995","display_name":"Kalina Metodieva","orcid":"https://orcid.org/0009-0006-3902-8424","observed_orcids":["https://orcid.org/0009-0006-3902-8424"]},"institutions":[{"id":"https://openalex.org/I2801117330","display_name":"Medical University Plovdiv","ror":"https://ror.org/02kzxd152","country_code":"BG","type":"education","lineage":["https://openalex.org/I2801117330"]}],"countries":["BG"],"is_corresponding":true,"raw_author_name":"Kalina Metodieva","raw_affiliation_strings":["Department of Medical Biochemistry, Faculty of Pharmacy, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria"],"raw_orcid":"https://orcid.org/0009-0006-3902-8424","affiliations":[{"raw_affiliation_string":"Department of Medical Biochemistry, Faculty of Pharmacy, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria","institution_ids":["https://openalex.org/I2801117330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085290426","display_name":"Iliyan Valeriev Dimitrov","orcid":"https://orcid.org/0000-0001-8988-0072","observed_orcids":["https://orcid.org/0000-0001-8988-0072"]},"institutions":[{"id":"https://openalex.org/I2801117330","display_name":"Medical University Plovdiv","ror":"https://ror.org/02kzxd152","country_code":"BG","type":"education","lineage":["https://openalex.org/I2801117330"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Iliyan Dimitrov","raw_affiliation_strings":["Department of Medical Biochemistry, Faculty of Pharmacy, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria"],"raw_orcid":"https://orcid.org/0000-0001-8988-0072","affiliations":[{"raw_affiliation_string":"Department of Medical Biochemistry, Faculty of Pharmacy, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria","institution_ids":["https://openalex.org/I2801117330"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072333762","display_name":"Anelia Veselinova Bivolarska","orcid":"https://orcid.org/0000-0002-2157-3858","observed_orcids":["https://orcid.org/0000-0002-2157-3858"]},"institutions":[{"id":"https://openalex.org/I2801117330","display_name":"Medical University Plovdiv","ror":"https://ror.org/02kzxd152","country_code":"BG","type":"education","lineage":["https://openalex.org/I2801117330"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Anelia Bivolarska","raw_affiliation_strings":["Department of Medical Biochemistry, Faculty of Pharmacy, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria"],"raw_orcid":"https://orcid.org/0000-0002-2157-3858","affiliations":[{"raw_affiliation_string":"Department of Medical Biochemistry, Faculty of Pharmacy, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria","institution_ids":["https://openalex.org/I2801117330"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5098657995"],"corresponding_institution_ids":["https://openalex.org/I2801117330"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.28433712,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":"21","first_page":"3333","last_page":"3333"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":0.923799991607666,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":0.923799991607666,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.06069999933242798,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.008299999870359898,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sarcopenia","display_name":"sarcopenia","score":1.0},{"id":"https://openalex.org/keywords/aronia-melanocarpa","display_name":"Aronia melanocarpa","score":0.9980000257492065},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8289999961853027},{"id":"https://openalex.org/keywords/chronic-low-grade-inflammation","display_name":"low-grade inflammation","score":0.8059999942779541},{"id":"https://openalex.org/keywords/polyphenols","display_name":"polyphenols","score":0.8690000176429749},{"id":"https://openalex.org/keywords/anthocyanins","display_name":"anthocyanins","score":0.9879999756813049},{"id":"https://openalex.org/keywords/proanthocyanidins","display_name":"proanthocyanidins","score":1.0},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.8999999761581421},{"id":"https://openalex.org/keywords/nrf2","display_name":"Nrf2","score":0.8360000252723694},{"id":"https://openalex.org/keywords/myostatin","display_name":"myostatin","score":0.7829999923706055},{"id":"https://openalex.org/keywords/irisin","display_name":"irisin","score":0.9959999918937683},{"id":"https://openalex.org/keywords/macrophage-polarization","display_name":"macrophage polarization","score":0.9509999752044678},{"id":"https://openalex.org/keywords/functional-foods","display_name":"functional foods","score":0.6769999861717224},{"id":"https://openalex.org/keywords/nutraceuticals","display_name":"nutraceuticals","score":0.9940000176429749},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"skeletal muscle","score":0.7360000014305115},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.6520000100135803},{"id":"https://openalex.org/keywords/mitochondrial-dysfunction","display_name":"mitochondrial dysfunction","score":0.4699999988079071},{"id":"https://openalex.org/keywords/satellite-cells","display_name":"satellite cells","score":0.7570000290870667}],"concepts":[{"id":"https://openalex.org/C17857428","wikidata":"https://www.wikidata.org/wiki/Q533025","display_name":"Nutraceutical","level":2,"score":0.8424000144004822},{"id":"https://openalex.org/C2776214593","wikidata":"https://www.wikidata.org/wiki/Q1787939","display_name":"Sarcopenia","level":2,"score":0.7372999787330627},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.652400016784668},{"id":"https://openalex.org/C2780132029","wikidata":"https://www.wikidata.org/wiki/Q752276","display_name":"Functional food","level":2,"score":0.5837000012397766},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5831000208854675},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.508899986743927},{"id":"https://openalex.org/C3019569299","wikidata":"https://www.wikidata.org/wiki/Q645858","display_name":"Food supplement","level":2,"score":0.36309999227523804},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3443000018596649},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.32350000739097595},{"id":"https://openalex.org/C3018263421","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Human studies","level":2,"score":0.3165999948978424},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.29409998655319214},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.26969999074935913},{"id":"https://openalex.org/C2993539680","wikidata":"https://www.wikidata.org/wiki/Q902552","display_name":"Antioxidant capacity","level":3,"score":0.26809999346733093},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.267300009727478},{"id":"https://openalex.org/C3018363719","wikidata":"https://www.wikidata.org/wiki/Q645858","display_name":"Dietary supplement","level":2,"score":0.2669000029563904}],"mesh":[{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D046936","descriptor_name":"Photinia","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D046936","descriptor_name":"Photinia","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D046936","descriptor_name":"Photinia","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D046936","descriptor_name":"Photinia","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D059808","descriptor_name":"Polyphenols","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D059808","descriptor_name":"Polyphenols","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D059808","descriptor_name":"Polyphenols","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D059808","descriptor_name":"Polyphenols","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3390/nu17213333","doi":"https://doi.org/10.3390/nu17213333","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu17213333","pdf_url":"https://www.mdpi.com/2072-6643/17/21/3333/pdf?version=1761223940","source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},{"id":"pmid:41228405","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41228405","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:11415027","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12610215","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/nu17213333","doi":"https://doi.org/10.3390/nu17213333","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu17213333","pdf_url":"https://www.mdpi.com/2072-6643/17/21/3333/pdf?version=1761223940","source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4415489698.pdf","grobid_xml":"https://content.openalex.org/works/W4415489698.grobid-xml"},"referenced_works_count":83,"referenced_works":["https://openalex.org/W29996380","https://openalex.org/W745996040","https://openalex.org/W1659590378","https://openalex.org/W1890731962","https://openalex.org/W1972557285","https://openalex.org/W1987857240","https://openalex.org/W1999765859","https://openalex.org/W2017357618","https://openalex.org/W2039436949","https://openalex.org/W2054897365","https://openalex.org/W2074127314","https://openalex.org/W2077102648","https://openalex.org/W2086667809","https://openalex.org/W2090026968","https://openalex.org/W2127835340","https://openalex.org/W2134036439","https://openalex.org/W2138555287","https://openalex.org/W2154248702","https://openalex.org/W2171139057","https://openalex.org/W2171742547","https://openalex.org/W2233620519","https://openalex.org/W2402945316","https://openalex.org/W2460249618","https://openalex.org/W2521574223","https://openalex.org/W2577591739","https://openalex.org/W2591792909","https://openalex.org/W2605674430","https://openalex.org/W2621432705","https://openalex.org/W2690979696","https://openalex.org/W2748094183","https://openalex.org/W2766495174","https://openalex.org/W2775780002","https://openalex.org/W2791564057","https://openalex.org/W2791950564","https://openalex.org/W2792991438","https://openalex.org/W2793011605","https://openalex.org/W2884081989","https://openalex.org/W2899278816","https://openalex.org/W2909362029","https://openalex.org/W2910379869","https://openalex.org/W2980847561","https://openalex.org/W3006467041","https://openalex.org/W3023973595","https://openalex.org/W3035616020","https://openalex.org/W3081112033","https://openalex.org/W3093698643","https://openalex.org/W3107344158","https://openalex.org/W3118708117","https://openalex.org/W3121720242","https://openalex.org/W3158577831","https://openalex.org/W3167563853","https://openalex.org/W3177140844","https://openalex.org/W3187269078","https://openalex.org/W3189795024","https://openalex.org/W3214914277","https://openalex.org/W4205123661","https://openalex.org/W4210977582","https://openalex.org/W4211144975","https://openalex.org/W4212972763","https://openalex.org/W4213091566","https://openalex.org/W4280557222","https://openalex.org/W4293590200","https://openalex.org/W4297505016","https://openalex.org/W4308971492","https://openalex.org/W4310382501","https://openalex.org/W4311216533","https://openalex.org/W4318206859","https://openalex.org/W4323923461","https://openalex.org/W4366245917","https://openalex.org/W4367673934","https://openalex.org/W4385475981","https://openalex.org/W4385620143","https://openalex.org/W4387415607","https://openalex.org/W4392360685","https://openalex.org/W4394681497","https://openalex.org/W4401014110","https://openalex.org/W4402987175","https://openalex.org/W4403202322","https://openalex.org/W4404076953","https://openalex.org/W4405640647","https://openalex.org/W4409111086","https://openalex.org/W4410300282","https://openalex.org/W4411744112"],"related_works":[],"abstract_inverted_index":{"Introduction:":[0],"Sarcopenia,":[1],"the":[2,62,71,151,239,253,269],"progressive":[3],"age-related":[4],"decline":[5],"in":[6,25,81,158,176,276],"skeletal":[7,139,234],"muscle":[8,140,177,235],"mass,":[9],"strength,":[10],"and":[11,20,30,43,54,73,79,105,115,126,142,156,171,173,195,201,208,225,228,249,255,262,273],"function,":[12],"represents":[13],"a":[14,92,186,190,246],"major":[15],"contributor":[16],"to":[17,66,86,205,267],"morbidity,":[18],"frailty,":[19],"reduced":[21],"quality":[22],"of":[23,61,107,193,257],"life":[24],"older":[26],"adults.":[27],"Oxidative":[28],"stress":[29,78,155],"chronic":[31],"low-grade":[32],"inflammation":[33,80,157],"are":[34],"increasingly":[35],"recognized":[36],"as":[37,83,85,91,185,245],"central":[38],"mechanisms":[39],"driving":[40],"its":[41],"onset":[42],"progression,":[44],"through":[45],"pathways":[46,231],"involving":[47],"mitochondrial":[48],"dysfunction,":[49],"impaired":[50],"satellite":[51],"cell":[52],"activity,":[53,224],"dysregulated":[55],"protein":[56],"turnover.":[57],"Objective:":[58],"The":[59],"purpose":[60],"following":[63],"manuscript":[64],"is":[65,183,265],"summarize":[67],"current":[68],"research":[69,264],"on":[70,138,161],"molecular":[72],"cellular":[74],"interactions":[75],"between":[76,113,153],"oxidative":[77,154],"sarcopenia,":[82,159],"well":[84],"assess":[87],"Aronia":[88,179],"melanocarpa\u2019s":[89,243],"potential":[90,244],"nutritional":[93,209],"intervention.":[94],"Methods:":[95],"A":[96],"narrative":[97,148],"review":[98,149],"was":[99],"conducted":[100],"by":[101],"searching":[102],"PubMed,":[103],"Scopus,":[104],"Web":[106],"Science":[108],"for":[109,233,252],"peer-reviewed":[110],"literature":[111],"published":[112],"2000":[114],"2024.":[116],"Keywords":[117],"included":[118],"\u201csarcopenia\u201d,":[119],"\u201coxidative":[120],"stress\u201d,":[121],"\u201cinflammation\u201d,":[122],"\u201cAronia":[123],"melanocarpa\u201d,":[124],"\u201cpolyphenols\u201d,":[125],"even":[127],"\u201cfunctional":[128],"foods\u201d.":[129],"Eligible":[130],"publications":[131],"provided":[132],"mechanistic,":[133],"preclinical,":[134,206],"or":[135],"clinical":[136,263],"findings":[137],"biology":[141],"A.":[143,211,242],"melanocarpa":[144,180,212],"bioactivity.":[145],"Results:":[146],"This":[147],"examines":[150],"relationship":[152],"focusing":[160],"NF-\u03baB-mediated":[162],"inflammatory":[163],"signaling,":[164],"Nrf-2-dependent":[165],"antioxidant":[166,200,222],"defenses,":[167],"myokines":[168],"like":[169],"myostatin":[170],"irisin,":[172],"macrophage":[174],"polarization":[175],"homeostasis.":[178],"(black":[181],"chokeberry)":[182],"highlighted":[184],"polyphenol-rich":[187],"fruit":[188],"with":[189],"distinct":[191],"profile":[192],"anthocyanins":[194],"proanthocyanidins":[196],"that":[197],"have":[198],"strong":[199],"anti-inflammatory":[202],"properties.":[203],"According":[204],"clinical,":[207],"studies,":[210],"bioactives":[213],"modulate":[214],"redox":[215],"balance,":[216],"suppress":[217],"pro-inflammatory":[218],"cytokine":[219],"production,":[220],"increase":[221],"enzyme":[223],"regulate":[226],"metabolic":[227],"regenerative":[229],"signaling":[230],"important":[232],"health.":[236],"Conclusions:":[237],"Overall,":[238],"data":[240],"suggest":[241],"functional":[247],"food":[248],"nutraceutical":[250],"candidate":[251],"prevention":[254],"treatment":[256],"sarcopenia.":[258],"However,":[259],"further":[260],"translational":[261],"needed":[266],"determine":[268],"appropriate":[270],"intake,":[271],"bioavailability,":[272],"long-term":[274],"efficacy":[275],"human":[277],"populations.":[278]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2025-10-24T00:00:00"}